Abstract:
INTRODUCTION:Guidelines recommendations for the treatment of COPD are poorly followed. This could be related to the complexity of classification and treatment algorithms. The purpose of this study was to validate a simpler dyspnea-based treatment algorithm for inhaled pharmacotherapy in stable COPD, comparing its concordance with the current Global Initiative for Obstructive Lung Disease (GOLD) guideline. METHODS:We enrolled patients who had been diagnosed with COPD in three primary care facilities and two tertiary hospitals in Spain. We determined anthropometric data, forced expiratory volume in the 1st second (percent), exacerbations, and dyspnea based on the modified Medical Research Council scale. We evaluated the new algorithm based on dyspnea and exacerbations and calculated the concordance with the current GOLD recommendations. RESULTS:We enrolled 100 patients in primary care and 150 attending specialized care in a respiratory clinic. There were differences in the sample distribution between cohorts with 41% vs 26% in grade A, 16% vs 12% in grade B, 16% vs 22% in grade C, and 27% vs 40% in grade D for primary and respiratory care, respectively (P=0.005). The coincidence of the algorithm with the GOLD recommendations in primary care was 93% and 91.8% in the respiratory care cohort. CONCLUSION:A simple dyspnea-based treatment algorithm for inhaled pharmacotherapy of COPD could be useful in the management of COPD patients and concurs very well with the recommended schema suggested by the GOLD initiative.
journal_name
Int J Chron Obstruct Pulmon Disauthors
Cabrera C,Casanova C,Martín Y,Mirabal V,Sánchez Mdel C,Álvarez F,Juliá G,Cabrera-Navarro P,García-Bello MÁ,Marín JM,de-Torres JP,Divo M,Celli Bdoi
10.2147/COPD.S100853subject
Has Abstractpub_date
2016-06-08 00:00:00pages
1217-22eissn
1176-9106issn
1178-2005pii
copd-11-1217journal_volume
11pub_type
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journal_title:International journal of chronic obstructive pulmonary disease
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,meta分析,评审
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