A functional SNP upstream of the ADRB2 gene is associated with COPD.

abstract：Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

更新日期：2018-03-06 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：:We hypothesized that bronchodilator treatment not only improves hyperinflation and endurance capacity but also muscular efficiency in stable chronic obstructive pulmonary disease (COPD). We aimed to demonstrate that tiotropium and salmeterol improve muscular efficiency compared with placebo. Twenty-five COPD patients ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van der Vaart H,Postma DS,Grevink R,Roemer W,ten Hacken N

更新日期：2011-01-01 00:00:00

abstract：Background:Thirty-day readmission in COPD is common and costly, but potentially preventable. The emergency department (ED) may be a setting for COPD readmission reduction efforts. Objective:To better understand COPD readmission through the ED, ascertain factors associated with 30-day readmission through the ED, and id...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rezaee ME,Ward CE,Nuanez B,Rezaee DA,Ditkoff J,Halalau A

更新日期：2017-12-27 00:00:00

abstract：OBJECTIVE:To determine the feasibility and efficacy of a six-month, cell phone-based exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD) following pulmonary rehabilitation. METHODS:Participants who completed a two-week run-in were randomly assigned to either MOBILE-Coached ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nguyen HQ,Gill DP,Wolpin S,Steele BG,Benditt JO

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed. PATIENTS AND METHODS:This prospective open-label single-arm clinical ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park TS,Hong Y,Lee JS,Oh SY,Lee SM,Kim N,Seo JB,Oh YM,Lee SD,Lee SW

更新日期：2015-07-29 00:00:00

abstract：PURPOSE:COPD remains under-recognized and under-treated. Much of early COPD care is given by primary care physicians but only when COPD is recognized. This survey explores the attitudes, beliefs, and knowledge related to COPD recognition, diagnosis, and treatment from family physicians and nurse practitioners (NPs) and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yawn BP,Wollan PC

更新日期：2008-01-01 00:00:00

abstract：:[This corrects the article on p. 2147 in vol. 13, PMID: 30034230.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-10-30 00:00:00

abstract：Background:Despite wide use of the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) 2011, little is known about between-stage transitions and what factors predict worsening transitions in patients with chronic obstructive pulmonary disease (COPD). Objective:To investigate the transition frequency bet...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bernabeu-Mora R,Sánchez-Martínez MP,Montilla-Herrador J,Oliveira-Sousa SL,Gacto-Sánchez M,Medina-Mirapeix F

更新日期：2020-06-30 00:00:00

abstract：OBJECTIVES:To explore the mediating role of protein interleukin-6 (IL-6) on the relationship between forced expiratory volume in 1 second (FEV1) and 6-minute walk distance (6MWD) and, further, to determine whether status variables (such as age, sex, and body mass index [BMI]) operate as moderators of this mediation rel...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Baldi S,Jose PE,Bruschi C,Pinna GD,Maestri R,Rezzani A,Bellinzona E,Fracchia C,Dacosto E,Crotti P,Montemartini S

更新日期：2014-10-07 00:00:00

abstract：:[This corrects the article on p. 3485 in vol. 13, PMID: 30498338.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-12-05 00:00:00

abstract：:Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Limpawattana P,Putraveephong S,Inthasuwan P,Boonsawat W,Theerakulpisut D,Chindaprasirt J

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. METHODS:Electronic databas...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blakemore A,Dickens C,Guthrie E,Bower P,Kontopantelis E,Afzal C,Coventry PA

更新日期：2014-05-20 00:00:00

abstract：Objective:The presence of both emphysema and airway wall thickening determined via volumetric computed tomography (CT) is defined as mixed phenotype. The long-term clinical course of this phenotype has not been studied in depth. This study compared the mixed phenotype to other phenotypes of chronic obstructive pulmonar...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lim JU,Kim EK,Lim SY,Lee JH,Lee JS,Lee SD,Oh YM,Rhee CK,KOLD Study Group.

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is one of the most debilitating somatic diseases, having anxiety and depression frequently as comorbidities. The coping style, the way in which the subject manages to control the difficult and stressful situations of life, can influence its evolutio...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Papava I,Oancea C,Enatescu VR,Bredicean AC,Dehelean L,Romosan RS,Timar B

更新日期：2016-06-20 00:00:00

abstract：:Currently, there is no cure for chronic obstructive pulmonary disease (COPD). The limited efficacy of current therapies for COPD indicates a pressing need to develop new treatments to prevent the progression of the disease, which consumes a significant amount of health care resources and is an important cause of morta...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Caramori G,Chung KF,Adcock IM

更新日期：2014-02-24 00:00:00

abstract：:[This corrects the article on p. 1401 in vol. 12, PMID: 28546748.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

更新日期：2011-01-01 00:00:00

abstract：:Bronchodilators represent the hallmark of symptomatic treatment of Chronic Obstructive Pulmonary Disease (COPD). There are four categories of bronchodilators: anticholinergics, methylxanthines, short-acting beta2-agonists, and long-acting beta2-agonists such as formoterol. Significant research has been performed to in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Steiropoulos P,Tzouvelekis A,Bouros D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Cardiac autonomic modulation (CAM) is impaired in patients with stable COPD. Exacerbation aggravates the patients' health status and functional capacity. While the clinical and functional effects of exacerbation are known, no studies investigated CAM during exacerbation and whether there is a relationship be...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kabbach EZ,Mazzuco A,Borghi-Silva A,Cabiddu R,Agnoleto AG,Barbosa JF,de Carvalho Junior LCS,Mendes RG

更新日期：2017-07-28 00:00:00

abstract：INTRODUCTION:COPD exacerbation negatively impacts the patient's quality of life and lung function, increases mortality, and increases socioeconomic costs. In a real-world setting, the majority of patients with COPD have mild-to-moderate airflow limitation. Therefore, it is important to evaluate COPD exacerbation in pat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim JK,Lee SH,Lee BH,Lee CY,Kim do J,Min KH,Kim SK,Yoo KH,Jung KS,Hwang YI

更新日期：2016-06-16 00:00:00

abstract：BACKGROUND:Dietary antioxidants have been suggested to have protective role against chronic obstructive pulmonary disease (COPD), but few prospective studies examined this relationship. The prospective study was conducted to evaluate the effect of dietary antioxidants on COPD risk and lung function in the Korean popula...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Joshi P,Kim WJ,Lee SA

更新日期：2015-10-08 00:00:00

abstract：Objectives:To describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada. Methods:We linked Alberta health databases to identify patients aged ≥35 years with incident COPD between April 2010 and March 2017. Incident cases were define...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tran DT,Akpinar I,Mayers I,Makhinova T,Jacobs P

更新日期：2019-09-26 00:00:00

abstract：:The course of COPD is punctuated by acute exacerbations that are associated with an increase in the morbidity and mortality related to this chronic disease and may contribute to its rate of progression. Therefore, preventing and treating exacerbations are major goals of COPD management. The role of tiotropium in the p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tashkin DP

更新日期：2010-02-18 00:00:00

abstract：OBJECTIVE:Comorbidities are characteristic of COPD. However, little is known about the secondary manifestations of COPD in the gastrointestinal tract. Therefore, we aimed to explore the long-term effects of gastrectomy in patients with spirometry-defined COPD or those at risk of COPD. PARTICIPANTS:Subjects included 87...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Saito H,Nomura K,Abe S,Motegi T,Ishii T,Hattori K,Kusunoki Y,Gemma A,Kida K

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are both common diseases that coexist frequently. Patients with both diseases have worse stable state health status when compared with patients with one of these diseases. In many outpatient clinics, health status is monitored routinely in C...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Berkhof FF,Metzemaekers L,Uil SM,Kerstjens HA,van den Berg JW

更新日期：2014-09-22 00:00:00

abstract：BACKGROUND:Recent studies that assessed the relevance of the blood eosinophil count as a biomarker in patients with COPD may have overestimated it because they included patients with asthma-COPD overlap syndrome (ACOS). We investigated the clinical implications of the blood eosinophil count in patients with non-ACOS CO...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Song JH,Lee CH,Kim JW,Lee WY,Jung JY,Park JH,Jung KS,Yoo KH,Park YB,Kim DK

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:The use of chlorofluorocarbons (CFCs) has contributed to the depletion of the stratospheric ozone layer resulting in serious health concerns. Ipratropium bromide/salbutamol sulphate CFC-pressurized metered-dose inhalers (IB/SAL-CFC pMDI) have been in widespread use for many years without any apparent ill con...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bhattacharya A,Bhargava S,Singh V,Talwar D,Whig J,Rebello J,Purandare S,Gogtay J

更新日期：2016-06-30 00:00:00

abstract：:Noninvasive ventilation (NIV) has been one of the major advances in respiratory medicine in the last decade. NIV improves quality of life, prolongs survival, and improves gas exchange and sleep quality in restrictive patients, but evidence available now does not allow us to establish clear criteria for prescribing NIV...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Díaz-Lobato S,Alises SM,Rodríguez EP

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Prediction of future exacerbations of chronic obstructive pulmonary disease (COPD) is a major concern for long-term management of this disease. AIM:To determine which of three multidimensional assessment systems (the body mass index, obstruction, dyspnea, and exercise capacity [BODE] index; dyspnea, obstruc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Motegi T,Jones RC,Ishii T,Hattori K,Kusunoki Y,Furutate R,Yamada K,Gemma A,Kida K

更新日期：2013-01-01 00:00:00