Acute exacerbation of COPD: is it the "stroke of the lungs"?

abstract：:Bronchoconstriction has been reported in asthma and chronic obstructive pulmonary disease (COPD) patients after administration of some aqueous inhalation solutions. We investigated the incidence of this event during long-term clinical trials of tiotropium delivered via Respimat(®) Soft Mist™ Inhaler (SMI). We retrospe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hodder R,Pavia D,Lee A,Bateman E

更新日期：2011-01-01 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD), a respiratory disease characterized by a progressive decline in lung function, is considered to be a leading cause of morbidity and mortality. Long-acting inhaled bronchodilators, such as long-acting β2 agonists (LABAs) or long-acting muscarinic antagonists (LAMAs), are th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramadan WH,Kabbara WK,El Khoury GM,Al Assir SA

更新日期：2015-10-30 00:00:00

abstract：Background:Telerehabilitation (TR) aimed at patients with COPD has shown promising effects on symptoms, physical function, and quality of life, but little research has been conducted to understand the impact of implementation on frontline health professionals. Therefore, the aim of this study was to examine the barrier...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Damhus CS,Emme C,Hansen H

更新日期：2018-08-17 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) seem to have several symptoms in common that impact health. However, methodological differences make this difficult to compare. AIM:Comparisons of symptoms, impact of symptoms on function and health between patients w...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Theander K,Hasselgren M,Luhr K,Eckerblad J,Unosson M,Karlsson I

更新日期：2014-07-18 00:00:00

abstract：Background:People living with both chronic obstructive pulmonary disease (COPD) and frailty have high potential to benefit from exercise-based interventions, including pulmonary rehabilitation, but face challenges completing them. Research to understand ways to optimise exercise-based interventions in this group is lac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Brighton LJ,Evans CJ,Man WDC,Maddocks M

更新日期：2020-04-20 00:00:00

abstract：Purpose:The unpredictable trajectory of COPD can present challenges for patients when faced with a decision regarding a do-not-resuscitate (DNR) directive. The current retrospective analysis was conducted to investigate factors associated with an early DNR decision (prior to last hospital admission) and differences in ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fu PK,Tung YC,Wang CY,Hwang SF,Lin SP,Hsu CY,Chen DR

更新日期：2018-08-14 00:00:00

abstract：BACKGROUND:Krasnoyarsk region is a territory with the widespread risk factors for chronic obstructive pulmonary disease (COPD) such as tobacco smoke, air pollution, and occupational exposure. An assessment of COPD prevalence based on medical diagnosis statistics underestimates the true COPD prevalence. This study aims ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Artyukhov IP,Arshukova IL,Dobretsova EA,Dugina TA,Shulmin AV,Demko IV

更新日期：2015-09-02 00:00:00

abstract：BACKGROUND:The hallmark of COPD is chronic airway inflammation, which may be mediated by renin-angiotensin system. The renin-angiotensin system blockers such as angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARBs) have exhibited anti-inflammatory and immunomodulatory effects in pa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim J,Lee JK,Heo EY,Chung HS,Kim DK

更新日期：2016-09-09 00:00:00

abstract：INTRODUCTION:Early palliative care is not a common practice for patients with COPD. Important barriers are the identification of patients for palliative care and the organization of such care in this patient group. OBJECTIVE:Pulmonologists have a central role in providing good quality palliative care for patients with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Dekhuijzen P,Vissers K,Engels Y,Heijdra Y

更新日期：2017-01-17 00:00:00

abstract：Background:Chronic obstructive pulmonary disease (COPD) is an age-related disease, and its incidence rate is increasing every year. MicroRNAs (miRNAs) play critical roles in the COPD process and function as key biomarkers or potential therapeutic targets for patients with COPD. However, the potential roles and function...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu X,Wang J,Luo H,Xu C,Chen X,Zhang R

更新日期：2020-12-31 00:00:00

abstract：Purpose:COPD has been associated with a high number of comorbidities and a relatively high level of health care resource utilization. This study aimed to estimate the social economic impact of COPD in the autonomous community of Extremadura (Spain) in 2015. Patients and methods:This is a retrospective observational st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Merino M,Villoro R,Hidalgo-Vega Á,Carmona C

更新日期：2018-08-21 00:00:00

abstract：Purpose:Previous studies have described the incidence, risk factors, and outcomes for patients with acute exacerbations of COPD (AECOPD) developing acute kidney injury (AKI). However, little is known about the differences between community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI) in patients with AECOPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cao CC,Chen DW,Li J,Ma MQ,Chen YB,Cao YZ,Hua X,Shao W,Wan X

更新日期：2018-07-17 00:00:00

abstract：:COPD is a chronic inflammatory disease of the lungs associated with an abnormal inflammatory response to noxious particles, the most prevalent of which is cigarette smoke. Studies have demonstrated that cigarette smoking is associated with activation of the bone marrow, and chronic smoking can lead to the inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Carlson AA,Smith EA,Reid DJ

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment. However, surprisingly little is known about gender-related differences for circulating inflammatory markers in COPD. PURPOSE:To ch...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Larsson S,Nordenson A,Glader P,Yoshihara S,Lindén A,Slinde F

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Noncommunicable diseases have become a public heath problem in India concomitant with economic development, leading to increases in tobacco consumption, obesity, and changes in diet and lifestyle. Although observation suggests that tobacco consumption is a major risk factor for deaths due to circulatory, pul...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Singh RB,Singh S,Chattopadhya P,Singh K,Singhz V,Kulshrestha SK,Tomar RS,Kumar R,Singh G,Mechirova V,Pella D

更新日期：2007-01-01 00:00:00

abstract：Background and purpose:While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bai C,Ichinose M,Lee SH,Lee KH,Jöns O,Bothner U,Zhao Y,Buhl R

更新日期：2017-11-20 00:00:00

abstract：BACKGROUND:Forced expiratory volume in 1 second (FEV1)/forced expiratory volume in 6 seconds (FEV6) has been proposed as an alternative to FEV1/forced vital capacity (FVC) for detecting airway obstruction. A fixed cut-off value for FEV1/FEV6 in a Korean population is lacking. We investigated a fixed cut-off for FEV1/FE...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KS,Jung JY,Park MS,Kim YS,Kim SK,Chang J,Song JH

更新日期：2016-08-19 00:00:00

abstract：Background:The risk of dying of lung cancer is up to eightfold higher in patients with COPD than in age- and gender-matched controls. The aim of this study was to investigate the factors associated with lung cancer in a large cohort of COPD patients from primary care centers. Methods:To analyze whether age, gender, so...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sandelin M,Mindus S,Thuresson M,Lisspers K,Ställberg B,Johansson G,Larsson K,Janson C

更新日期：2018-06-06 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is one of the most debilitating somatic diseases, having anxiety and depression frequently as comorbidities. The coping style, the way in which the subject manages to control the difficult and stressful situations of life, can influence its evolutio...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Papava I,Oancea C,Enatescu VR,Bredicean AC,Dehelean L,Romosan RS,Timar B

更新日期：2016-06-20 00:00:00

abstract：:[This corrects the article on p. 2147 in vol. 13, PMID: 30034230.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Alpha-1-antitrypsin deficiency (AATD) is associated with a high risk for the development of early-onset emphysema and liver disease. A large majority of subjects with severe AATD carry the ZZ genotype, which can be easily detected. Another rare pathologic variant, the Mmalton allele, causes a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Belmonte I,Barrecheguren M,López-Martínez RM,Esquinas C,Rodríguez E,Miravitlles M,Rodríguez-Frías F

更新日期：2016-10-11 00:00:00

abstract：Background:Phase III studies demonstrated efficacy and safety of nebulized glycopyrrolate inhalation solution (GLY) in subjects with COPD. Secondary analyses were performed to examine the effect of background long-acting beta2-agonist (LABA) use on the efficacy and safety of nebulized GLY. Methods:In two 12-week place...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kerwin EM,Tosiello R,Price B,Sanjar S,Goodin T

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:Glycopyrronium is a once-daily (od) long-acting muscarinic antagonist for the maintenance treatment of chronic obstructive pulmonary disease (COPD). The GLOW7 study evaluated the efficacy and safety of od glycopyrronium 50 μg in predominantly Chinese patients with moderate-to-severe COPD. METHODS:In this 26...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang C,Sun T,Huang Y,Humphries M,Bai L,Li L,Wang Q,Kho P,Firth R,D'Andrea P

更新日期：2015-01-05 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00

abstract：Purpose:We compared clinical characteristics of COPD patients according to symptom variability and evaluated the effect of symptom variability during the first year of enrollment on clinical outcomes of COPD. Methods:We analyzed COPD patients' data from the Korean Obstructive Lung Disease (KOLD) cohort. Symptom variab...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim MA,Suh MK,Park J,Kim JH,Kim TH,Kim EK,Oh YM,Lee SD,Lee JH

更新日期：2019-09-20 00:00:00

abstract：INTRODUCTION:Effects of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) patients with severely impaired health status are poorly documented since these patients are usually excluded from clinical trials. This retrospective, observational study aims to study the impact of disease on health ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Ranst D,Otten H,Meijer JW,van 't Hul AJ

更新日期：2011-01-01 00:00:00

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：BACKGROUND:The relationship between prior health care utilization and respiratory medication prescriptions in an unselected population of patients with COPD is not known. METHODS:We determined the prescribed respiratory medications and respiratory and nonrespiratory health care encounters in 523 Veterans with COPD at ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Seaman J,Leonard AC,Panos RJ

更新日期：2010-04-07 00:00:00