Lack of paradoxical bronchoconstriction after administration of tiotropium via Respimat® Soft Mist™ Inhaler in COPD.

abstract：Purpose:COPD is a multisystem disease and there is a need for clinical serum markers that can assess the decline in lung and muscle function in COPD. The goal of this study was to evaluate the potential association of serum club-cell protein 16 (CC16), α-1 acid glycoprotein (AGP) and total sialic acid (TSA) with spirom...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Qaisar R,Karim A,Muhammad T

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Glycopyrronium is a once-daily (od) long-acting muscarinic antagonist for the maintenance treatment of chronic obstructive pulmonary disease (COPD). The GLOW7 study evaluated the efficacy and safety of od glycopyrronium 50 μg in predominantly Chinese patients with moderate-to-severe COPD. METHODS:In this 26...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang C,Sun T,Huang Y,Humphries M,Bai L,Li L,Wang Q,Kho P,Firth R,D'Andrea P

更新日期：2015-01-05 00:00:00

abstract：:Pulmonary emphysema is usually the result of chronic exposure to cigarette smoke in at risk individuals. To investigate the hypothesis that lung damage in emphysema results from coincident weakening in the structural properties of the tissue and increased mechanical forces--as one explanation of the continued developm...

journal_title：International journal of chronic obstructive pulmonary disease

authors： de Ryk J,Thiesse J,Namati E,McLennan G

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the relationship of smoking duration with respiratory symptoms and history of chronic obstructive pulmonary disease (COPD) in the South Carolina Behavioral Risk Factor Surveillance System survey in 2012. METHODS:Data from 4,135 adults aged ≥45 years with a smoking his...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Y,Pleasants RA,Croft JB,Wheaton AG,Heidari K,Malarcher AM,Ohar JA,Kraft M,Mannino DM,Strange C

更新日期：2015-07-21 00:00:00

abstract：INTRODUCTION:According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as mortal...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sawalha S,Hedman L,Rönmark E,Lundbäck B,Lindberg A

更新日期：2017-04-24 00:00:00

abstract：Rationale:COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives:To assess and synthesize the available evidence among...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ntritsos G,Franek J,Belbasis L,Christou MA,Markozannes G,Altman P,Fogel R,Sayre T,Ntzani EE,Evangelou E

更新日期：2018-05-10 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：BACKGROUND:COPD patients are often prescribed multiple medications for their respiratory disease and comorbidities. This can lead to complex medication regimens resulting in poor adherence, medication errors, and drug-drug interactions. The relationship between clinical outcomes and medication burden beyond medication ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Negewo NA,Gibson PG,Wark PA,Simpson JL,McDonald VM

更新日期：2017-10-06 00:00:00

abstract：Objective:The presence of both emphysema and airway wall thickening determined via volumetric computed tomography (CT) is defined as mixed phenotype. The long-term clinical course of this phenotype has not been studied in depth. This study compared the mixed phenotype to other phenotypes of chronic obstructive pulmonar...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lim JU,Kim EK,Lim SY,Lee JH,Lee JS,Lee SD,Oh YM,Rhee CK,KOLD Study Group.

更新日期：2019-12-30 00:00:00

abstract：Background:This study examines the effects of the COPD-specific health promoting self-management intervention "Better living with COPD" on different self-management-related domains, self-efficacy, and sense of coherence (SOC). Methods:In a randomized controlled design, 182 people with COPD were allocated to either an ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bringsvor HB,Langeland E,Oftedal BF,Skaug K,Assmus J,Bentsen SB

更新日期：2018-11-08 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：BACKGROUND:The diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Z,Lin L,Liu X

更新日期：2017-03-15 00:00:00

abstract：Purpose:Chest physiotherapy is an important tool in the treatment of COPD. Intrapulmonary percussive ventilation (IPV) and high-frequency chest wall oscillation (HFCWO) are techniques designed to create a global percussion of the lung which removes secretions and probably clears the peripheral bronchial tree. We tested...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nicolini A,Grecchi B,Ferrari-Bravo M,Barlascini C

更新日期：2018-02-16 00:00:00

abstract：Objective:Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods:A total of 543 patients with COPD (FEV1 <80% and FEV1/FVC <70%) were included between January 2003 and January 2004. Patients were stable for at least 6 weeks before inclusion and were followed for 5 yea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Aramburu A,Arostegui I,Moraza J,Barrio I,Aburto M,García-Loizaga A,Uranga A,Zabala T,Quintana JM,Esteban C

更新日期：2019-03-07 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：Background:Adherence to treatment is key to achieve desired outcomes. In COPD, adherence is generally suboptimal and is impaired by treatment complexity. Objective:To estimate the clinical and economic impact of an improvement in treatment adherence due to an increased use of once-daily single-inhaler triple therapy (...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Miravitlles M,Marín A,Huerta A,Carcedo D,Villacampa A,Puig-Junoy J

更新日期：2020-07-10 00:00:00

abstract：:Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Limpawattana P,Putraveephong S,Inthasuwan P,Boonsawat W,Theerakulpisut D,Chindaprasirt J

更新日期：2017-04-18 00:00:00

abstract：:Currently, there is no cure for chronic obstructive pulmonary disease (COPD). The limited efficacy of current therapies for COPD indicates a pressing need to develop new treatments to prevent the progression of the disease, which consumes a significant amount of health care resources and is an important cause of morta...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Caramori G,Chung KF,Adcock IM

更新日期：2014-02-24 00:00:00

abstract：:COPD is uniquely situated as a chronic disease at the beginning of the 21st century; it is not only an established major cause of mortality and morbidity but is increasing in prevalence despite current medical interventions. In addition COPD is not a stable disease but its natural history is punctuated by periods of a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wilkinson T,Wedzicha JA

更新日期：2006-01-01 00:00:00

abstract：Background:Chronic obstructive pulmonary disease (COPD) is prevalent and poses a heavy burden worldwide. However, patients know little about COPD, and primary health care providers have poor therapy capability in China. Enjoying Breathing Program aims to establish a new comprehensive COPD patient management system, inc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jia C,Zhang C,Fang F,Huang K,Dong F,Gu X,Niu H,Li S,Wang C,Yang T

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) experience respiratory symptoms, which impair quality of life. This pooled analysis of two Phase III studies assessed the impact of aclidinium/formoterol on patients with COPD categorized by symptom status. METHODS:Data were pooled from two 24-week,...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Miravitlles M,Chapman KR,Chuecos F,Ribera A,Gil EG

更新日期：2016-08-29 00:00:00

abstract：:[This corrects the article on p. 2147 in vol. 13, PMID: 30034230.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-10-30 00:00:00

abstract：:Cigarette smoking is an established cause of lung cancer. However, pulmonary fibrosis is also an independent risk factor for the development of lung cancer. Smoking-related interstitial fibrosis (SRIF) has recently been reported. We hypothesized that adenocarcinomas in lungs with SRIF might show distinct molecular cha...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Primiani A,Dias-Santagata D,Iafrate AJ,Kradin RL

更新日期：2014-05-24 00:00:00

abstract：Objective:Chronic obstructive pulmonary disease (COPD) is associated with atherosclerosis. Previous studies including limited sample sizes have shown the prevalence of peripheral arterial occlusive disease (PAOD) among COPD patients. We sought to investigate the incidence of PAOD among COPD patients in Taiwan using a n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liao KM,Kuo LT,Lu HY

更新日期：2019-07-04 00:00:00

abstract：BACKGROUND:With the growing burden of COPD and associated morbidity and mortality, a need for self-management has been identified. The Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD) manual was developed to support self-management in COPD patients. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blackmore C,Johnson-Warrington VL,Williams JE,Apps LD,Young HM,Bourne C,Singh SJ

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:To estimate the potential cost savings by following the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline recommendations in patients being treated for chronic obstructive pulmonary disease (COPD) with the combination of long-acting β(2)-agonist (LABA), long-acting muscarinic an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asche CV,Leader S,Plauschinat C,Raparla S,Yan M,Ye X,Young D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is a short questionnaire that has facilitated health status measurements in subjects with COPD. However, it remains controversial as to whether the CAT can be used as a suitable substitute for the St George's Respiratory Questionnaire (SG...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morishita-Katsu M,Nishimura K,Taniguchi H,Kimura T,Kondoh Y,Kataoka K,Ogawa T,Watanabe F,Arizono S,Nishiyama O,Nakayasu K,Imaizumi K,Hasegawa Y

更新日期：2016-07-07 00:00:00

abstract：Background:People living with both chronic obstructive pulmonary disease (COPD) and frailty have high potential to benefit from exercise-based interventions, including pulmonary rehabilitation, but face challenges completing them. Research to understand ways to optimise exercise-based interventions in this group is lac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Brighton LJ,Evans CJ,Man WDC,Maddocks M

更新日期：2020-04-20 00:00:00

abstract：Introduction:COPD is an inflammatory airway pathology associated with recurrent infection by nontypeable Haemophilus influenzae (NTHi) that is not effectively managed by macrolide antibiotic therapy. We hypothesised that NTHi is able to reside intracellularly within COPD-derived airway epithelial cells (AEC), and that ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Poh WP,Kicic A,Lester SE,Nguyen PT,Bakaletz LO,Reynolds PN,Hodge S,Roscioli E

更新日期：2020-06-04 00:00:00

abstract：BACKGROUND:Previous studies have relied on international spirometry criteria to diagnose COPD in patients with lung cancer without considering the effect lung cancer might have on spirometric results. The aim of this study was to examine the prevalence of COPD and emphysema at the time of primary lung cancer diagnosis ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ytterstad E,Moe PC,Hjalmarsen A

更新日期：2016-03-23 00:00:00