Circulating Biomarkers of Handgrip Strength and Lung Function in Chronic Obstructive Pulmonary Disease.

abstract：BACKGROUND:The combination of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a selective long-acting β₂ agonist, is in development for the treatment of chronic obstructive pulmonary disease (COPD). This study evaluated the pharmacokinetics, safety and tolerability, and pharmacod...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mehta R,Kelleher D,Preece A,Hughes S,Crater G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Z,Lin L,Liu X

更新日期：2017-03-15 00:00:00

abstract：Background:In contrast to cigarette smoking, the association between water pipe smoking and airway hyperresponsiveness remains widely unexplored. Methods:A bronchoprovocation challenge with mannitol was performed in young adults recruited at the University of Basel, Switzerland. Subjects were categorized as acute wate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Scherr A,Schmidlin J,Albisser S,Tamm M,Stolz D

更新日期：2018-01-03 00:00:00

abstract：BACKGROUND:COPD-related deaths are increasing in Japan, with ~5.3 million people at risk. METHODS:The SHINE was a 26-week, multicenter, randomized, double-blind, parallel-group study that evaluated safety and efficacy of indacaterol (IND)/glycopyrronium (GLY) 110/50 μg once daily (od) compared with GLY 50 μg od, IND 1...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hashimoto S,Ikeuchi H,Murata S,Kitawaki T,Ikeda K,Banerji D

更新日期：2016-10-11 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：BACKGROUND:Despite the availability of national and international guidelines, evidence suggests that chronic obstructive pulmonary disease (COPD) treatment is not always prescribed according to recommendations. This study evaluated the current management of patients with COPD using a large UK primary-care database. ME...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Price D,West D,Brusselle G,Gruffydd-Jones K,Jones R,Miravitlles M,Rossi A,Hutton C,Ashton VL,Stewart R,Bichel K

更新日期：2014-08-27 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00

abstract：Introduction:Training in correct inhaler use, ideally in person or by video demonstration, can minimize errors but is rarely provided in clinics. This open-label, low-intervention study evaluated critical error rates with dry-powder inhalers (DPIs), before and after training, in patients with chronic obstructive pulmon...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Collier DJ,Wielders P,van der Palen J,Heyes L,Midwinter D,Collison K,Preece A,Barnes N,Sharma R

更新日期：2020-06-09 00:00:00

abstract：Purpose:To date, no consensus exists on the effects of systemic steroid use on pneumonic chronic obstructive pulmonary disease (COPD) exacerbation owing to trial design issues in previous trials involving these conditions. This multicenter study aimed to evaluate more precisely the effectiveness of the use of systemic ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shiroshita A,Shiba H,Tanaka Y,Nishi A,Sato K,Shirakawa C,Kataoka Y

更新日期：2020-10-19 00:00:00

abstract：Purpose:Previous studies have described the incidence, risk factors, and outcomes for patients with acute exacerbations of COPD (AECOPD) developing acute kidney injury (AKI). However, little is known about the differences between community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI) in patients with AECOPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cao CC,Chen DW,Li J,Ma MQ,Chen YB,Cao YZ,Hua X,Shao W,Wan X

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Pulmonary Daoyin (PD) (evolved from ancient Chinese daoyin skills), is a rehabilitation technology that combines specially designed movements of the arms and body and controlled breathing exercises, to improve the physiological and psychological status of patients with chronic respiratory disea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang HL,Li JS,Yu XQ,Li SY,Halmurat U,Xie Y,Wang YF,Li FS,Wang MH

更新日期：2017-08-04 00:00:00

abstract：OBJECTIVE:To determine the feasibility and efficacy of a six-month, cell phone-based exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD) following pulmonary rehabilitation. METHODS:Participants who completed a two-week run-in were randomly assigned to either MOBILE-Coached ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nguyen HQ,Gill DP,Wolpin S,Steele BG,Benditt JO

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Effects of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) patients with severely impaired health status are poorly documented since these patients are usually excluded from clinical trials. This retrospective, observational study aims to study the impact of disease on health ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Ranst D,Otten H,Meijer JW,van 't Hul AJ

更新日期：2011-01-01 00:00:00

abstract：Background:Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metr...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Adhikari TB,Acharya P,Högman M,Neupane D,Karki A,Drews A,Cooper BG,Sigsgaard T,Kallestrup P

更新日期：2020-09-29 00:00:00

abstract：:[This corrects the article on p. 2147 in vol. 13, PMID: 30034230.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-10-30 00:00:00

abstract：OBJECTIVE:To investigate the gene-expression profile of chronic obstructive pulmonary disease (COPD) patients and explore the possible therapeutic targets. METHODS:The microarray raw dataset GSE29133, including three COPD samples and three normal samples, was obtained from Gene Expression Omnibus. After data preproces...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wei L,Xu D,Qian Y,Huang G,Ma W,Liu F,Shen Y,Wang Z,Li L,Zhang S,Chen Y

更新日期：2015-06-10 00:00:00

abstract：Background:In COPD disturbed sleep is related to exacerbation frequency, poor quality of life, and early mortality. We developed the Manchester Respiratory-related Sleep Symptoms scale (MaRSS) to assess sleep-time symptoms in COPD. Methods:Focus groups including COPD and age-matched controls were used to develop an it...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Khan N,Vestbo J,Garrow A,Karur P,Kolsum U,Tyson S,Singh D,Yorke J

更新日期：2018-11-29 00:00:00

abstract：INTRODUCTION:Early palliative care is not a common practice for patients with COPD. Important barriers are the identification of patients for palliative care and the organization of such care in this patient group. OBJECTIVE:Pulmonologists have a central role in providing good quality palliative care for patients with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Dekhuijzen P,Vissers K,Engels Y,Heijdra Y

更新日期：2017-01-17 00:00:00

abstract：:COPD is a complex, heterogeneous condition. Even in the early clinical stages, COPD carries a significant burden, with breathlessness frequently leading to a reduction in exercise capacity and changes that correlate with long-term patient outcomes and mortality. Implementation of an effective management strategy is re...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ariel A,Altraja A,Belevskiy A,Boros PW,Danila E,Fležar M,Koblizek V,Fridlender ZG,Kostov K,Krams A,Milenkovic B,Somfay A,Tkacova R,Tudoric N,Ulmeanu R,Valipour A

更新日期：2017-12-21 00:00:00

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：:Cigarette smoking results in the accumulation of iron both systemically and locally, in the lung thereby causing imbalance in iron homeostasis. This disruption in iron homeostasis can be associated with oxidative stress and consequent tissue injury. Therefore, in this study, we tested the association between iron home...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ghio AJ,Hilborn ED

更新日期：2017-07-18 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a global health problem. Being a progressive disease characterized by inflammation and predominantly caused by tobacco smoking, it deteriorates pulmonary and skeletal muscle functioning, and reduces physical behavior, societal participation and quality of life. During th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： de Boer WI,Yao H,Rahman I

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:COPD is a debilitating disease that affects patients' daily lives. One's daily physical activity (DPA) decreases due to multifactorial causes, and this decrease is correlated with a poor prognosis in COPD patients. Muscle wasting may at least be partly due to increased activity of the ubiquitin proteasome pa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee KY,Chen TT,Chiang LL,Chuang HC,Feng PH,Liu WT,Chen KY,Ho SC

更新日期：2017-05-22 00:00:00

abstract：:Smoking-related interstitial lung disease (ILD) consists of a heterogeneous group of disorders that are considered a distinct entity. The 2013 American Thoracic Society and European Respiratory Society recommendations classified respiratory bronchiolitis (RB)/RB-ILD and desquamative interstitial pneumonia (DIP) as smo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bak SH,Lee HY

更新日期：2017-11-01 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:Although chronic obstructive pulmonary disease (COPD) is closely associated with gastroesophageal reflux disease (GERD), the clinical significance of laryngopharyngeal reflux (LPR) is not fully understood in COPD. METHODS:Prospective cohorts were established among 118 patients with COPD from March 2013 to J...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jung YH,Lee DY,Kim DW,Park SS,Heo EY,Chung HS,Kim DK

更新日期：2015-07-15 00:00:00

abstract：Background:Since most internal medicine nurses work with chronic obstructive pulmonary disease (COPD) patients daily, their ability to meet the needs of COPD patients is an important issue. Our study aimed to assess COPD-related knowledge in internal medicine nurses. Methods:A descriptive cross-sectional study includi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ma Y,Peng Y,Chen P,Nie N,Chen Y

更新日期：2019-12-17 00:00:00

abstract：Objectives:To describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada. Methods:We linked Alberta health databases to identify patients aged ≥35 years with incident COPD between April 2010 and March 2017. Incident cases were define...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tran DT,Akpinar I,Mayers I,Makhinova T,Jacobs P

更新日期：2019-09-26 00:00:00

abstract：PURPOSE:The purpose of this study was to define the prevalence of undiagnosed airflow obstruction (AO) among subjects with a history of smoking but no previous diagnosis of chronic lung disease. The finding of AO likely represents diagnosis of chronic obstructive pulmonary disease. PATIENTS:People aged ≥30 years with ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fu SN,Yu WC,Wong CK,Lam MC

更新日期：2016-09-27 00:00:00