Overlaps and uncertainties of smoking-related idiopathic interstitial pneumonias.

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) experience respiratory symptoms, which impair quality of life. This pooled analysis of two Phase III studies assessed the impact of aclidinium/formoterol on patients with COPD categorized by symptom status. METHODS:Data were pooled from two 24-week,...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Miravitlles M,Chapman KR,Chuecos F,Ribera A,Gil EG

更新日期：2016-08-29 00:00:00

abstract：Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chro...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak N

更新日期：2018-08-10 00:00:00

abstract：Background:Upper limb muscle strength plays an important role in respiratory and pulmonary function, and limited research focuses on the role of strength and endurance of the elbow extensor and flexor. This study was conducted to accurately assess upper limb muscle function and quantified associations with pulmonary fu...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu X,Li P,Wang Z,Lu Y,Li N,Xiao L,Duan H,Wang Z,Li J,Shan C,Wu W

更新日期：2019-09-05 00:00:00

abstract：Purpose:We compared clinical characteristics of COPD patients according to symptom variability and evaluated the effect of symptom variability during the first year of enrollment on clinical outcomes of COPD. Methods:We analyzed COPD patients' data from the Korean Obstructive Lung Disease (KOLD) cohort. Symptom variab...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim MA,Suh MK,Park J,Kim JH,Kim TH,Kim EK,Oh YM,Lee SD,Lee JH

更新日期：2019-09-20 00:00:00

abstract：BACKGROUND:Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. METHODS:Cross-sectional analysis was carried ou...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Perez T,Burgel PR,Paillasseur JL,Caillaud D,Deslée G,Chanez P,Roche N,INITIATIVES BPCO Scientific Committee.

更新日期：2015-08-18 00:00:00

abstract：:TRPM8 plays a key role in COPD. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity. Thus, the aim of this study was to evaluate the possible association between single nucleotide polymorphisms (SNPs) in TRPM8 and COPD or PH in COPD among the Chinese Han population. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xiong M,Wang J,Guo M,Zhou Q,Lu W

更新日期：2016-10-14 00:00:00

abstract：Background:Previous studies have suggested that β2-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods:In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Li JX,Fu WP,Zhang J,Zhang XH,Sun C,Dai LM,Zhong L,Yu L,Zhang YP

更新日期：2018-03-16 00:00:00

abstract：Purpose:Waterpipe (WP) use has become a global trend in young populations. However, there are few well-controlled studies focusing specifically on the chronic effects of exclusive WP use on young adults' respiratory health. We sought to compare in young adults the burden of respiratory symptoms in regular WP smokers (W...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hawari FI,Obeidat NA,Abu Alhalawa M,Al-Busaidi Z,Amara B,Baddar S,Elhabiby M,Elkholy H

更新日期：2019-08-13 00:00:00

abstract：Objective:To determine the clinical and economic consequences of inhaled corticosteroid doses and particle size in patients on triple-inhalation therapy for COPD. Methods:Patients aged ≥40 years who initiated treatment with multi-inhaler triple-inhaled therapy between 1 January 2015 and 31 March were included and foll...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sicras-Mainar A,de Abajo FJ,Izquierdo-Alonso JL

更新日期：2020-12-09 00:00:00

abstract：:Noninvasive ventilation (NIV) has been one of the major advances in respiratory medicine in the last decade. NIV improves quality of life, prolongs survival, and improves gas exchange and sleep quality in restrictive patients, but evidence available now does not allow us to establish clear criteria for prescribing NIV...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Díaz-Lobato S,Alises SM,Rodríguez EP

更新日期：2006-01-01 00:00:00

abstract：Objectives:To describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada. Methods:We linked Alberta health databases to identify patients aged ≥35 years with incident COPD between April 2010 and March 2017. Incident cases were define...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tran DT,Akpinar I,Mayers I,Makhinova T,Jacobs P

更新日期：2019-09-26 00:00:00

abstract：OBJECTIVES:COPD is an abnormal inflammatory response characterized by decreased expression of TLR2 in patients, which is suggested to induce invasive pulmonary aspergillosis (IPA). MicroRNAs (miRNAs) have been shown to play important roles in the pathogenesis of human respiratory system disorders. Therefore, the aim of...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xu H,Wu Y,Li L,Yuan W,Zhang D,Yan Q,Guo Z,Huang W

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:Presence of chronic obstructive pulmonary disease (COPD) in heart failure (HF) has prognostic and therapeutic implications. Exact prevalence estimates are lacking because most previous studies estimated the prevalence of COPD among HF patients while unstable and in the presence of pulmonary congestion. METH...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Valk MJ,Broekhuizen BD,Mosterd A,Zuithoff NP,Hoes AW,Rutten FH

更新日期：2015-06-26 00:00:00

abstract：Purpose:To evaluate clinical periodontal status and microbiologic pathogens in patients with chronic obstructive pulmonary disease (COPD) and periodontitis. Patients and Methods:We conducted a case-control study of 60 periodontitis patients with COPD (case group) and 60 periodontitis patients with normal pulmonary fun...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou X,Wang J,Liu W,Huang X,Song Y,Wang Z,Jia X

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Little is known regarding the relationship between balance impairments and physical activity in COPD. There has been no study investigating the relationship between balance and objectively measured physical activity. Here we investigated the association between balance and physical activity measured by an ac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Iwakura M,Okura K,Shibata K,Kawagoshi A,Sugawara K,Takahashi H,Shioya T

更新日期：2016-07-01 00:00:00

abstract：Purpose:Peripheral blood eosinophilic counts are susceptible to many factors and have variability over time. There are limited studies on association of blood eosinophilia with long-term mortality of chronic obstructive pulmonary disease (COPD) patients and these results remain controversial. Our aims were to explore t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang Y,Liang LR,Zhang S,Lu Y,Chen YY,Shi HZ,Lin YX

更新日期：2020-05-19 00:00:00

abstract：Background:In COPD disturbed sleep is related to exacerbation frequency, poor quality of life, and early mortality. We developed the Manchester Respiratory-related Sleep Symptoms scale (MaRSS) to assess sleep-time symptoms in COPD. Methods:Focus groups including COPD and age-matched controls were used to develop an it...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Khan N,Vestbo J,Garrow A,Karur P,Kolsum U,Tyson S,Singh D,Yorke J

更新日期：2018-11-29 00:00:00

abstract：OBJECTIVES:Emphysema is one of the prognostic factors for rapid lung function decline in patients with COPD, but the impact of incidentally detected emphysema on population without spirometric abnormalities has not been evaluated. This study aimed to determine whether emphysema detected upon computed tomography (CT) sc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Koo HK,Jin KN,Kim DK,Chung HS,Lee CH

更新日期：2016-01-29 00:00:00

abstract：Introduction:Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily durati...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sundh J,Ahmadi Z,Ekström M

更新日期：2018-08-28 00:00:00

abstract：:COPD is uniquely situated as a chronic disease at the beginning of the 21st century; it is not only an established major cause of mortality and morbidity but is increasing in prevalence despite current medical interventions. In addition COPD is not a stable disease but its natural history is punctuated by periods of a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wilkinson T,Wedzicha JA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Prediction of future exacerbations of chronic obstructive pulmonary disease (COPD) is a major concern for long-term management of this disease. AIM:To determine which of three multidimensional assessment systems (the body mass index, obstruction, dyspnea, and exercise capacity [BODE] index; dyspnea, obstruc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Motegi T,Jones RC,Ishii T,Hattori K,Kusunoki Y,Furutate R,Yamada K,Gemma A,Kida K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Glycopyrronium is a once-daily (od) long-acting muscarinic antagonist for the maintenance treatment of chronic obstructive pulmonary disease (COPD). The GLOW7 study evaluated the efficacy and safety of od glycopyrronium 50 μg in predominantly Chinese patients with moderate-to-severe COPD. METHODS:In this 26...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang C,Sun T,Huang Y,Humphries M,Bai L,Li L,Wang Q,Kho P,Firth R,D'Andrea P

更新日期：2015-01-05 00:00:00

abstract：:The aim of the study was to assess the budgetary impact of funding smoking-cessation drugs in COPD patients in Spain. A hybrid model (cohort and Markov) was developed for a 5-year time horizon. Only approved cessation drugs (varenicline, bupropion, and nicotine replacement therapy) were considered. Irrespective of the...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jiménez-Ruiz CA,Solano-Reina S,Signes-Costa J,de Higes-Martinez E,Granda-Orive JI,Lorza-Blasco JJ,Riesco-Miranda JA,Altet-Gomez N,Barrueco M,Oyagüez I,Rejas J,SESEPARAR’s Integrated Tobacco Research Program.

更新日期：2015-09-24 00:00:00

abstract：:Influenza viruses cause respiratory tract infections that in patients with underlying lung diseases such as chronic obstructive pulmonary disease (COPD) are associated with exacerbations and excess morbidity and mortality. Typically, influenza B is associated with relatively mild, local outbreaks, whereas influenza A ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wesseling G

更新日期：2007-01-01 00:00:00

abstract：:Background: Pulmonary hypertension (PH) is one of the most common complications developed during the course of chronic obstructive pulmonary disease (COPD). Platelet activation plays an important role in its pathophysiology, and mean platelet volume (MPV) is considered a respectable index of platelet activation. The a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mohamed MF,Ali A,Abbas A,Awad MS,Gouda M,Sediq AM

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND:Lung volume reduction (LVR) improves breathing mechanics by reducing hyperinflation. Lobar selection usually focuses on choosing the most destroyed emphysematous lobes as seen on an inspiratory CT scan. However, it has never been shown to what extent these densitometric CT parameters predict the least deflat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hetzel J,Boeckeler M,Horger M,Ehab A,Kloth C,Wagner R,Freitag L,Slebos DJ,Lewis RA,Haentschel M

更新日期：2017-08-30 00:00:00

abstract：BACKGROUND:To estimate the potential cost savings by following the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline recommendations in patients being treated for chronic obstructive pulmonary disease (COPD) with the combination of long-acting β(2)-agonist (LABA), long-acting muscarinic an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asche CV,Leader S,Plauschinat C,Raparla S,Yan M,Ye X,Young D

更新日期：2012-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease with an increasing prevalence worldwide. Its potential consequences, including reduced function and reduced social participation, are likely to be associated with decreased health-related quality of life (HRQoL). However, illness percept...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bonsaksen T,Haukeland-Parker S,Lerdal A,Fagermoen MS

更新日期：2014-01-01 00:00:00

abstract：:Though the guidelines for the optimal management of chronic obstructive pulmonary disease (COPD) following an acute exacerbation (AE) are well established, issues associated with poor adherence to nonpharmacological interventions such as self-management advice and pulmonary rehabilitation will impact on hospital readm...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Harrison SL,Goldstein R,Desveaux L,Tulloch V,Brooks D

更新日期：2014-10-29 00:00:00

abstract：INTRODUCTION:Guidelines recommendations for the treatment of COPD are poorly followed. This could be related to the complexity of classification and treatment algorithms. The purpose of this study was to validate a simpler dyspnea-based treatment algorithm for inhaled pharmacotherapy in stable COPD, comparing its conco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cabrera C,Casanova C,Martín Y,Mirabal V,Sánchez Mdel C,Álvarez F,Juliá G,Cabrera-Navarro P,García-Bello MÁ,Marín JM,de-Torres JP,Divo M,Celli B

更新日期：2016-06-08 00:00:00