Human insulin-specific immunoglobulin G antibody and hypoglycemic attacks after the injection of gold thioglucose.

abstract：:We examined the distribution of nuclear T3 in mature rat brain with the aim of determining specific targets of thyroid hormones within this tissue. Saturation experiments, performed in 9 different structures of the brain and in 4 parts of the cortex, revealed the presence of a single class of binding sites with a mean...

journal_title：Journal of endocrinological investigation

authors： Ruel J,Faure R,Dussault JH

更新日期：1985-08-01 00:00:00

abstract：PURPOSE:Hypercortisolism has detrimental effects on bone metabolism with the consequences of bone loss and bone fractures. We aimed to evaluate the frequency of vertebral fragility fractures and to determine the factors associated with Cushing's syndrome (CS). METHODS:A total of 135 patients diagnosed with Cushing's s...

journal_title：Journal of endocrinological investigation

authors： Apaydın T,Yavuz DG

更新日期：2021-01-09 00:00:00

abstract：:Erythrocytes glutathione (GSH) levels were measured in erythrocytes from 33 subjects, at baseline and after 2-hour glucose loading in order to investigate the effect of glucose ingestion on the erythrocyte GSH. According to the World Health Organisation criteria 18 subjects had normal glucose tolerance (NGT)(mean age ...

journal_title：Journal of endocrinological investigation

authors： Konukoğlu D,Hatemi H,Ozer EM,Gönen S,Akçay T

更新日期：1997-09-01 00:00:00

abstract：:The type of dietary fat affects the action of insulin by changes induced in the fatty acid composition of cell membranes. Little is known, however, about the effects of dietary fatty acids on insulin secretion or the possible relation between the fatty acid composition of the membrane phospholipids and insulin secreti...

journal_title：Journal of endocrinological investigation

authors： Tinahones FJ,Pareja A,Soriguer FJ,Gómez-Zumaquero JM,Cardona F,Rojo-Martínez G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Myogenesis is susceptible to the availability of nutrients and humoral factors and suboptimal fetal environments affect the number of myofibers and muscle mass. AIM:We examined the mechanisms regulating cell cycle progression and arrest in skeletal myoblasts. MATERIALS AND METHODS:Mouse C2C12 myoblasts wer...

journal_title：Journal of endocrinological investigation

authors： Grabiec K,Gajewska M,Milewska M,Błaszczyk M,Grzelkowska-Kowalczyk K

更新日期：2014-03-01 00:00:00

abstract：:Traumatic brain injury (TBI) combined with fractures of long bones or large joints is often associated with enhanced osteogenesis (early fracture healing accompanied by hypertrophic callus formation and/or heterotopic ossifications). Humoral factors that cause enhanced osteogenesis in patients with TBI are not yet ide...

journal_title：Journal of endocrinological investigation

authors： Wildburger R,Zarkovic N,Tonkovic G,Skoric T,Frech S,Hartleb M,Loncaric I,Zarkovic K

更新日期：1998-02-01 00:00:00

abstract：:During a multicentric pilot screening program for congenital hypothyroidism a comparison between the results obtained from Urbino, an area characterized by low iodine supply and endemic goiter, and Rome, a non-endemic area, has been made. The evaluation of neonatal urinary iodine excretion in the two areas showed sign...

journal_title：Journal of endocrinological investigation

authors： Carta Sorcini M,Diodato A,Fazzini C,Sabini G,Carta S,Grandolfo ME,Guidi M,Vasta M,Locatelli De Maestri J,Donati L

更新日期：1988-04-01 00:00:00

abstract：:Subclinical hypothyroidism (SH) is a common clinical problem, particularly in adulthood and the elderly. Its prevalence is conditioned by several etiological and risk factors. The highest age- and sex-specific rates are in women over 60. SH may be associated with manifestations of mild thyroid failure, which may rever...

journal_title：Journal of endocrinological investigation

authors： Arrigo T,Wasniewska M,Crisafulli G,Lombardo F,Messina MF,Rulli I,Salzano G,Valenzise M,Zirilli G,De Luca F

更新日期：2008-01-01 00:00:00

abstract：:Our aim was to investigate the effect of GnRH-agonist (GnRH-a) induced suppression of plasma sex steroids on serum GH, insulin like growth factor-I (IGF-I) and insulin levels after an oral glucose load (OGTT) in women with polycystic ovary syndrome (PCOS). Serum insulin, GH and IGF-I levels during a 75-g 4-h OGTT were...

journal_title：Journal of endocrinological investigation

authors： Tropeano G,Liberale I,Vuolo IP,Barini A,Caroli G,Carfagna P,Menini E

更新日期：1997-04-01 00:00:00

abstract：:Osteocalcin (OC) concentration, a specific index of bone formation, was measured in 29 female patients with microprolactinoma (serum prolactin, PRL: 105 +/- 10.9 ng/ml; mean +/- SE). Mean OC levels were significantly lower than in controls (1.7 +/- 0.2 vs 5.1 +/- 0.3 ng/ml; p less than 0.001), being below the normal r...

journal_title：Journal of endocrinological investigation

authors： Sartorio A,Conti A,Ambrosi B,Muratori M,Morabito F,Faglia G

更新日期：1990-05-01 00:00:00

abstract：:Ghrelin is a 28-amino-acid hormone produced mainly by the stomach which strongly promotes food intake. It is the only known peripheral orexigenic hormone that induces the release of GH. Ghrelin has been proposed as a link between the enteric system and central regulation of energy balance and growth. Although it has r...

journal_title：Journal of endocrinological investigation

authors： Seoane LM,Al-Massadi O,Barreiro F,Dieguez C,Casanueva FF

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Female Sexual Dysfunction (FSD) is a still poorly studied and underdiagnosed condition. The aim of the study was to produce an improved version of FSFI-6 (6-Item Version of the Female Sexual Function Index), entitled Female Sexual Dysfunction Index-6 (FSDI-6), and to estimate its accuracy as a screening instrum...

journal_title：Journal of endocrinological investigation

authors： Maseroli E,Fanni E,Fambrini M,Ragghianti B,Limoncin E,Mannucci E,Maggi M,Vignozzi L

更新日期：2016-04-01 00:00:00

abstract：:It has been shown that human calcitonin (hCT) is absorbed through the nasal mucosa when administered together with promoters like sodium glycocholate (SGC) or dihydrofusinate. The aim of this study was to compare the clinical and metabolic effect of intranasal (in) and intramuscular (im) hCT in patients with osteoporo...

journal_title：Journal of endocrinological investigation

authors： Pontiroli AE,Pajetta E,Calderara A,Alberetto M,Pozza G,Manganelli V,Resmini G,Tessari L,Maresca V

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Hyperglycemia is a common, but not well-characterized side effect of glucocorticoid treatment. AIM:To study the effect of pulse dexamethasone treatment on carbohydrate metabolism among multiple myeloma patients. MATERIAL/SUBJECTS AND METHODS:A randomized crossover observational study in a teaching hospital...

journal_title：Journal of endocrinological investigation

authors： Véber O,Wilde A,Demeter J,Tamás G,Mucsi I,Tabák AG

更新日期：2014-04-01 00:00:00

abstract：:The effects of graded infusions of atrial natriuretic peptide (ANP) on hemodynamics, renal function, plasma renin activity (PRA) and plasma arginine vasopressin (AVP) were investigated in a two part study in 6 volunteers. Three 30-min iv infusions of either saline control or ANP at graded rates of 4, 10 and 40 pmol kg...

journal_title：Journal of endocrinological investigation

authors： Williams TD,Walsh KP,Pitts E,Sutton R,Lightman SL

更新日期：1988-01-01 00:00:00

abstract：:We describe a patient with Cushing's syndrome and metastatic small cell lung cancer. The plasma ACTH concentrations were markedly elevated (91.6 pmol/L), and the AM cortisol did not suppress by > 50% overnight after administration of 8 mg dexamethasone, both consistent with the ectopic ACTH syndrome. Immunohistochemic...

journal_title：Journal of endocrinological investigation

authors： Auchus RJ,Mastorakos G,Friedman TC,Chrousos GP

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:The determination of (a) iodine deficiency, and (b) the relation between the iodized salt consumption in the Isparta province of Turkey. METHODS:Five hundred students between 6-11 yr of age were evaluated. With a questionnaire, the subjects were asked whether they were using iodine-containing salt or not. Af...

journal_title：Journal of endocrinological investigation

authors： Cetin H,Kisioglu AN,Gursoy A,Bilaloglu E,Ayata A

更新日期：2006-09-01 00:00:00

abstract：:In healthy pregnant women, the regulation of thyroid function depends upon several factors. Three factors act independently to increase thyroid hormone requirements: 1) the marked increase in the binding capacity of serum due to high TBG levels; 2) the direct stimulation of the thyroid by human chorionic gonadotropin,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D

更新日期：1993-05-01 00:00:00

abstract：:Few data are available on serum free thyroid hormone concentration in patients with T3-toxicosis. In this study total and free T4 and T3 and TBG were evaluated in 35 subjects with T3-toxicosis, including 12 with untreated Graves' disease, 5 Graves' patients on methimazole treatment, 13 with autonomous adenoma, 3 with ...

journal_title：Journal of endocrinological investigation

authors： Ferrari C,Romussi M,Rampini P,Benco R,Boghen M,Paracchi A,Frezzati S

更新日期：1983-02-01 00:00:00

abstract：:We treated a 10 6/12 year old prepubertal male with hypophosphatemic rickets, who was growing poorly despite appropriate treatment with calcitriol and phosphate, with exogenous growth hormone (for an initial trial period of 4 months, followed by 14 months of continuous treatment at a dose of 4 IU three times weekly) e...

journal_title：Journal of endocrinological investigation

authors： Lanes R,Harrison HE

更新日期：1990-11-01 00:00:00

abstract：:In acromegaly, clinical features are of the utmost importance, and biochemical confirmation is rarely difficult. However, some clinically manifest acromegalics have subtle abnormalities in GH secretion resulting in post-glucose GH nadir in the designated "normal" range with high IGF-I levels. Clinical decision may be ...

journal_title：Journal of endocrinological investigation

authors： Popovic V

更新日期：2005-01-01 00:00:00

abstract：:Hexarelin (Hex) is a synthetic hexapeptide with potent GH-releasing activity in both animals and men. Aim of this study was to evaluate the GH response to a maximal dose of Hex and GH-releasing hormone (GHRH) in a group of patients with Prader-Willi syndrome (PWS). Seven patients (4 boys and 3 girls, age 2.4-14.2 yr) ...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Raguso G,Palmiotto T,Faedda A,Gurreri F,Neri G,Deghenghi R,Loche S

更新日期：1998-09-01 00:00:00

abstract：:It has been reported that adult obese subjects present a reduced growth hormone secretion. As no data are available in the pubertal period, which is characterized in lean subjects by an increased spontaneous growth hormone secretion, the growth hormone circadian concentration was studied in a group of 18 obese male su...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Del Monte P,Fortini P,Resentini M,Morabito F,Giordano G

更新日期：1988-07-01 00:00:00

abstract：:The physiological pulsatile secretion of GH in humans might be important for the metabolic effects of GH. In the treatment of GH-deficient (GHD) patients, the most common regimen is a single sc injection at bedtime. It has not been completely established if this is the optimal mode of GH administration during long-ter...

journal_title：Journal of endocrinological investigation

authors： Höybye C,Rudling M

更新日期：2006-12-01 00:00:00

abstract：:Pyoderma gangrenosum is a rare chronic and recurrent skin disease characterized by progressing lesions from papulopustules to large necrotic sterile ulcers. Its definite etiology remains unknown. In a 40-year-old woman with typical pyoderma gangrenosum an intrasellar mass with suprasellar extension was diagnosed and r...

journal_title：Journal of endocrinological investigation

authors： Chanson P,Timsit J,Kujas M,Violante A,Guillausseau PJ,Derome PJ,Warnet A,Lubetzki J

更新日期：1990-09-01 00:00:00

abstract：:The assessment of growth hormone (GH) secretory status is often difficult because of the intermittent nature of GH release and resulting wide swings in plasma GH levels. Urinary GH excretion holds promise as an index of integrated plasma GH free of this limitation, but technical problems have prevented its use until r...

journal_title：Journal of endocrinological investigation

authors： Winer LM,Shaw MA,Baumann G

更新日期：1989-07-01 00:00:00

abstract：:The present study reports the biochemical and immunohistochemical findings in the cytosol of a Hürthle cell carcinoma as compared with that of normal thyroid tissue. Sephadex G-200 chromatography of the extract derived from a Hürthle cell carcinoma and from normal thyroid tissue revealed three identical pools. Pool I ...

journal_title：Journal of endocrinological investigation

authors： De Keyser L,Layfield L,Van Herle A,Costin A,Lewin K

更新日期：1984-10-01 00:00:00

abstract：:N-Terminal (1-76) portion of proopiomelanocortin (hNT) was measured in normals, Addison's, Nelson's, Cushing's disease, and in dexamethasone suppressible hyperaldosteronism (DSH) by using a specific homologous RIA. Mean basal immunoreactive hNT level was 94.2 +/- 6 pg/ml (mean +/- SE) in normal subjects. In Cushing's ...

journal_title：Journal of endocrinological investigation

authors： Boscaro M,Giacomazzi P,Sonino N,Fallo F,Girard F,Bertagna X,Mantero F

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:In our previous study, we introduced a rat model of polycystic ovary syndrome (PCOS) induced by prenatal exposure to a single dose of testosterone on embryonic day 20. In the current study, we aimed to investigate whether prenatal exposure to a single dose of testosterone could also induce metabolic disturbance...

journal_title：Journal of endocrinological investigation

authors： Noroozzadeh M,Ramezani Tehrani F,Sedaghat K,Godini A,Azizi F

更新日期：2015-05-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00