Long-term GH treatment of GH-deficient adults: comparison between one and two daily injections.

abstract：:Plasma adrenocorticotropic hormone (ACTH) and beta-endorphin (beta-EP) concentrations were measured by radioimmunoassay in 122 newborns, born vaginally after spontaneous labor between the 38th and the 41st week of pregnancy. Blood samples were taken from umbilical cord in 10 newborns and from antecubital vein in the r...

journal_title：Journal of endocrinological investigation

authors： Gemelli M,Mamì C,Manganaro R,De Luca F,Saja A,Costa G

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Vitamin D exerts pleiotropic effects and few studies are available in the Italian population. AIM:Aim of our study was to evaluate vitamin D status in children living in Northern Italy. METHODS:We studied vitamin D levels in a population of 113 normal weight (NW) and 444 obese (OB) children, prepubertal an...

journal_title：Journal of endocrinological investigation

authors： Bellone S,Esposito S,Giglione E,Genoni G,Fiorito C,Petri A,Bona G,Prodam F

更新日期：2014-09-01 00:00:00

abstract：:Not only thyroid adenomas and carcinomas, but also the majority of single and well delimited goiter nodules, even if morphologically heterogeneous, are of clonal origin. However, it is still unknown whether the nodules of rapidly growing, recurrent goiters are clonal or polyclonal. We investigated by PCR-based analysi...

journal_title：Journal of endocrinological investigation

authors： Harrer P,Broecker M,Zint A,Schatz H,Zumtobel V,Derwahl M

更新日期：1998-06-01 00:00:00

abstract：PURPOSE:Post-finasteride syndrome (PFS) has been reported in a subset of patients treated with finasteride (an inhibitor of the enzyme 5alpha-reductase) for androgenetic alopecia. These patients showed, despite the suspension of the treatment, a variety of persistent symptoms, like sexual dysfunction and cognitive and ...

journal_title：Journal of endocrinological investigation

authors： Borgo F,Macandog AD,Diviccaro S,Falvo E,Giatti S,Cavaletti G,Melcangi RC

更新日期：2020-09-19 00:00:00

abstract：BACKGROUND:Visfatin [pre-B cell colony- enhancing factor (PBEF)] is a cytokine highly expressed in visceral fat that exhibits insulin-mimetic properties. However, its role in insulin-resistant states, such as in metabolic syndrome (MetS), remains largely unknown. OBJECTIVE:To investigate the possible differences of pl...

journal_title：Journal of endocrinological investigation

authors： Filippatos TD,Derdemezis CS,Kiortsis DN,Tselepis AD,Elisaf MS

更新日期：2007-04-01 00:00:00

abstract：:Aim of the study was to compare urinary galactosyl-hydroxylysine (GHyl), deoxypyridinoline (D-Pyr) and pyridinoline (Pyr) before and after 5 to 9 months of hormone replacement therapy (HRT) in postmenopausal women. The urinary markers were measured by HPLC in the second void of fasting samples and were expressed as ra...

journal_title：Journal of endocrinological investigation

authors： Marabini R,Sirtori P,Chionna R,Barzizza L,Rubinacci A

更新日期：1996-03-01 00:00:00

abstract：:Circulating TSH bioactivity may vary in several clinical and experimental conditions. Since the reliability of the current methods for the measurement of TSH bioactivity is limited, a new bioassay based on cAMP accumulation in Chinese Hamster Ovary cells transfected with recombinant human TSH receptor (CHO-R) was set ...

journal_title：Journal of endocrinological investigation

authors： Persani L,Tonacchera M,Beck-Peccoz P,Vitti P,Mammoli C,Chiovato L,Elisei R,Faglia G,Ludgate M,Vassart G

更新日期：1993-07-01 00:00:00

abstract：:Endocrine changes have been reported in treated epileptic subjects, who often exhibit sexual dysfunctions, but the endocrine effects of single antiepileptic drugs have not been completely elucidated. In this study we have investigated the influence of phenobarbital (PB) on adenopituitary function and on peripheral sex...

journal_title：Journal of endocrinological investigation

authors： Murialdo G,Manni R,De Maria A,Bonura ML,Polleri A,Tartara A

更新日期：1987-02-01 00:00:00

abstract：:Thyrocytes from normal and goitrous portions of the thyroid gland from a patient with an enormous (635 gm) goiter were cultured in media, and their relative abilities to uptake thymidine, synthesize DNA, and secrete Tg and T4 were assessed. Tg, T4 and the ratio Tg/T4 in media at 72 h were 120 micrograms/dl, 1.6 microg...

journal_title：Journal of endocrinological investigation

authors： Tseng YC,Burman KD,Baker JR Jr,D'Avis J,Wartofsky L

更新日期：1987-10-01 00:00:00

abstract：:The authors report the results of a correlation study between the direct Immunobead Test (d-IBT) and other techniques for antisperm antibodies detection. The Gelatin Agglutination Test (GAT) and Tray Agglutination Test (TAT) were used to detect antibodies in blood serum and seminal plasma ("indirect methods"). The Dir...

journal_title：Journal of endocrinological investigation

authors： Dondero F,Lenzi A,Gandini L,Lombardo F,Culasso F

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The aim of the study was to evaluate diurnal blood pressure (BP) profiles in patients with primary aldosteronism and to compare them to those in subjects with essential hypertension. The effects of specific therapy on the circadian BP profiles have been studied. MATERIALS AND METHODS:Sixty-four patients wit...

journal_title：Journal of endocrinological investigation

authors： Zacharieva S,Orbetzova M,Elenkova A,Stoynev A,Yaneva M,Schigarminova R,Kalinov K,Nachev E

更新日期：2006-01-01 00:00:00

abstract：:Molecular diagnostics of the LHR gene was conducted in a 5-year-old boy with clinical symptoms and hormonal profile typical of precocious puberty. His parents and 4 sisters were also diagnosed. Single-strand conformation polymorphism analysis under temperature gradient conditions (Multitemperature SSCP) of 3 overlappi...

journal_title：Journal of endocrinological investigation

authors： Ignacak M,Starzyk J,Dziatkowiak H,Trzeciak WH

更新日期：2002-03-01 00:00:00

abstract：AIM:In the last years there has been a progressive reduction of the average duration of sleep and an increase in the incidence of sleep disturbances. At the same time, an increase of the incidence of the metabolic syndrome has been described, partly attributable to the progressive worsening of dietary habits and the in...

journal_title：Journal of endocrinological investigation

authors： Gramaglia E,Ramella Gigliardi V,Olivetti I,Tomelini M,Belcastro S,Calvi E,Dotta A,Ghigo E,Benso A,Broglio F

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Two yr after legislation of salt iodization of 40 parts per million (ppm) in 1994, goiter was still endemic and urinary iodine concentration (UIC) remained elevated in many provinces of Iran. Goiter prevalence and UIC were compared 2 and 7 yr after sustained consumption of uniformly iodized salt by Iranian ho...

journal_title：Journal of endocrinological investigation

authors： Azizi F,Mehran L,Sheikholeslam R,Ordookhani A,Naghavi M,Hedayati M,Padyab M,Mirmiran P

更新日期：2008-05-01 00:00:00

abstract：:The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

journal_title：Journal of endocrinological investigation

authors： Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

更新日期：1989-01-01 00:00:00

abstract：:Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been analyzed for total pro...

journal_title：Journal of endocrinological investigation

authors： Federspil G,Vettor R,Bossi A,Sicolo N

更新日期：1979-04-01 00:00:00

abstract：:The activities of total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were measured in cancerous and non-cancerous adjacent tissues from 15 patients with follicular thyroid cancer containing single nodule. SOD and GSH-Px activities were found lower but malondialdehyde levels hi...

journal_title：Journal of endocrinological investigation

authors： Durak I,Bayram F,Kavutcu M,Canbolat O,Oztürk HS

更新日期：1996-05-01 00:00:00

abstract：:The aim of the study was to assess iodine status in over 3800 young male subjects aged 18, living in 6 different provinces of Piemonte and in Aosta Valley, Italy. A cross-sectional study on 3837 young male subjects undergoing medical evaluation preliminary to military enrolment was performed. Spot urine samples were o...

journal_title：Journal of endocrinological investigation

authors： Fonzo D,Germano L,Gallone G,Migliardi M

更新日期：2003-12-01 00:00:00

abstract：PURPOSE:This study investigated the relationship between seasonal variations in 25-hydroxyvitamin D (25(OH)D) levels and growth in prepubertal children during both the pretreatment year and the first year of GH treatment. METHODS:The study included 249 short prepubertal children with a broad range of GH secretion, GH(...

journal_title：Journal of endocrinological investigation

authors： Andersson B,Swolin-Eide D,Kriström B,Gelander L,Magnusson P,Albertsson-Wikland K

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The aim of this study is to analyze our preliminary results from minimally invasive video-assisted parathyroidectomy (MIVAP) and demonstrate the feasibility of MIVAP also in non-referral centers. MATERIAL AND METHODS:During a period from June 2005 to January 2008, in the General Surgery Department of Univer...

journal_title：Journal of endocrinological investigation

authors： Dobrinja C,Trevisan G,Liguori G

更新日期：2009-02-01 00:00:00

abstract：:Thyrotropin binding characteristics and adenylate cyclase (AC) activity of thyroid plasma membranes were studied in 52 tissues from normal and diseased human thyroids. Data from normal glands, Graves' goiters, non toxic multinodular goiters and nodular and perinodular tissue of toxic nodular goiters show the same basa...

journal_title：Journal of endocrinological investigation

authors： Carayon P,Guibout M,Lissitzky S

更新日期：1978-10-01 00:00:00

abstract：:Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...

journal_title：Journal of endocrinological investigation

authors： Liu D,Zhu Y,Yang C,Long J,Yao C,Li J,Wang S

更新日期：2012-05-01 00:00:00

abstract：:We have measured eye muscle antibodies, in immunoblotting, in the serum from five patients with severe ophthalmopathy associated with Graves' hyperthyroidism who underwent plasmapheresis, correlating their levels with clinical features of the eye disorder and response to treatment. Blood taken before each plasma excha...

journal_title：Journal of endocrinological investigation

authors： Atabay C,Schrooyen M,Zhang ZG,Salvi M,Glinoer D,Wall JR

更新日期：1993-10-01 00:00:00

abstract：:Plasma insulin immunoreactivity (IRI) results from high molecular weight substances with insulin immunoreactivity (HWIRI), proinsulin (PI) and insulin (I). Their respective concentrations and percentages of IRI were determined preoperatively in the hepatic and peripheral circulations and after surgery in the latter tw...

journal_title：Journal of endocrinological investigation

authors： Villaume C,Beck B,Pointel JP,Drouin P,Debry G

更新日期：1982-09-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：:Cimetidine, an H2 receptor antagonist, is a potent stimulant of PRL secretion in normal women. In the present study, the PRL response to cimetidine was studied in 34 normal pregnant women and their fetuses during labor. Serum maternal PRL levels increased significantly after the acute iv injection of 400 mg cimetidine...

journal_title：Journal of endocrinological investigation

authors： Messinis IE,Tsirkas N,Diamantis K,Vasakos S,Tsolas O,Lolis D

更新日期：1988-12-01 00:00:00

abstract：:The occurrence of metabolic bone disease in patients with renal dysfunction is due to the key role played by the kidney in regulating calcium-phosphate metabolism. The incidence of hip fractures in end-stage renal disease is 3- to 4-fold higher than the general population, while poor data about vertebral fractures sho...

journal_title：Journal of endocrinological investigation

authors： Fusaro M,D'Angelo A,Scalzo G,Gallieni M,Giannini S,Guglielmi G

更新日期：2010-05-01 00:00:00

abstract：:Between 1973 and 1980, 93 patients with Graves' disease underwent subtotal thyroidectomy by the same surgeon (the size of thyroid remnant was 4 g per side). No case of operative mortality, no case of thyroid storm nor of surgical complications occurred. Three months after surgery 40% of patients were euthyroid, 25% ha...

journal_title：Journal of endocrinological investigation

authors： Busnardo B,Girelli ME,Rubello D,Eccher C,Betterle C

更新日期：1988-05-01 00:00:00

abstract：:In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resul...

journal_title：Journal of endocrinological investigation

authors： Eichler I,Frisch H,Eichler HG,Soukop W

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To assess the relationship of waist circumference and weight/height ratio with height, and their association with components of the metabolic syndrome, in Type 2 diabetic patients. DESIGN:multicenter cross-sectional survey on a cohort enrolled in a prospective observational study. SUBJECTS:13,232 patients (...

journal_title：Journal of endocrinological investigation

authors： Mannucci E,Alegiani SS,Monami M,Sarli E,Avogaro A,DAI (Diabetes and Informatics) Study Group.

更新日期：2004-06-01 00:00:00