Influence of environmental iodine deficiency on neonatal thyroid screening results.

Abstract:

:During a multicentric pilot screening program for congenital hypothyroidism a comparison between the results obtained from Urbino, an area characterized by low iodine supply and endemic goiter, and Rome, a non-endemic area, has been made. The evaluation of neonatal urinary iodine excretion in the two areas showed significantly lower iodine urinary excretion levels in Urbino than in Rome. A shift of TSH at screening toward higher values as well as a higher percentage of recall in Urbino area than in Rome was observed. This finding, which well correlates with a low environmental iodine supply, emphasizes the importance of screening for congenital hypothyroidism as a suitable index of the presence and action of goitrogenic factors in the environment.

journal_name

J Endocrinol Invest

authors

Carta Sorcini M,Diodato A,Fazzini C,Sabini G,Carta S,Grandolfo ME,Guidi M,Vasta M,Locatelli De Maestri J,Donati L

doi

10.1007/BF03350156

subject

Has Abstract,Author List Incomplete

pub_date

1988-04-01 00:00:00

pages

309-12

issue

4

eissn

0391-4097

issn

1720-8386

journal_volume

11

pub_type

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