当前位置： SCI文献检索 > JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION期刊下所有文献 > Osteocalcin levels in patients with microprolactinoma before and during medical treatment.

Osteocalcin levels in patients with microprolactinoma before and during medical treatment.

Abstract：

:Osteocalcin (OC) concentration, a specific index of bone formation, was measured in 29 female patients with microprolactinoma (serum prolactin, PRL: 105 +/- 10.9 ng/ml; mean +/- SE). Mean OC levels were significantly lower than in controls (1.7 +/- 0.2 vs 5.1 +/- 0.3 ng/ml; p less than 0.001), being below the normal range in 28 out of 29 patients. All patients were treated with dopaminergic agents (dihydroergocriptine, bromocriptine or cabergoline). After treatment mean serum PRL levels were significantly reduced (12 +/- 3.1 ng/ml; p less than 0.001), a full normalization being obtained in 26 patients. There were no significant differences in both basal and after treatment PRL levels among patients treated with different drugs, although a greater PRL decrease was induced by cabergoline. Serum OC levels significantly increased after 12 month therapy (4.7 +/- 0.6 ng/ml, p less than 0.001), a normal concentration being reached in 14 of 29 cases. During treatment there were no significant differences in serum estradiol and PRL concentrations between patients who normalized or not their OC levels, while the reduction in PRL levels with respect to baseline was more pronounced in the former group. The absolute increase in OC levels positively correlated with serum PRL decrements (p less than 0.01). It is noteworthy that serum OC normalized in 1/10 patients during dihydroergocriptine, 3/8 during bromocriptine and 10/11 during cabergoline. Four patients, previously treated with dihydroergocriptine and bromocriptine without normalizing OC and PRL levels, underwent a second course of therapy with cabergoline and then normalized OC concentrations.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

J Endocrinol Invest

journal_title

Journal of endocrinological investigation

authors

Sartorio A,Conti A,Ambrosi B,Muratori M,Morabito F,Faglia G

doi

10.1007/BF03350694

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

419-22

issue

5

eissn

0391-4097

issn

1720-8386

journal_volume

13

pub_type

杂志文章

相关文献

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION文献大全
  • Effect of cimetidine on maternal and fetal prolactin secretion during labor.

    abstract：:Cimetidine, an H2 receptor antagonist, is a potent stimulant of PRL secretion in normal women. In the present study, the PRL response to cimetidine was studied in 34 normal pregnant women and their fetuses during labor. Serum maternal PRL levels increased significantly after the acute iv injection of 400 mg cimetidine...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350225

    authors： Messinis IE,Tsirkas N,Diamantis K,Vasakos S,Tsolas O,Lolis D

    更新日期：1988-12-01 00:00:00

  • Serum 25-hydroxyvitamin D status among Saudi children with and without a history of fracture.

    abstract：BACKGROUND:The significance of vitamin D deficiency in the incidence of bone fractures in children has been under investigated. Here, we aimed to associate serum 25-hydroxyvitamin D levels and fractures in Saudi children. MATERIALS AND METHODS:This cross-sectional study was conducted in 1022 Saudi children without fra...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-016-0496-7

    authors： Al-Daghri NM,Aljohani N,Rahman S,Sabico S,Al-Attas OS,Alokail MS,Al-Ajlan A,Chrousos GP

    更新日期：2016-10-01 00:00:00

  • Remission of acromegaly after treatment withdrawal in patients controlled by cabergoline alone or in combination with octreotide: results from a multicenter study.

    abstract：PURPOSE:Remission of acromegaly has been reported after somatostatin analogs withdrawal, but not after withdrawal of combination therapy with cabergoline, and only in case reports of patients controlled by cabergoline alone. METHODS:To establish the remission rates (normal IGF-1 for age/sex: IGF-1 ≤ 1.00 xULN) after w...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s40618-016-0595-5

    authors： Casagrande A,Bronstein MD,Jallad RS,Mota JI,Tabet A,Abucham J

    更新日期：2017-05-01 00:00:00

  • 25-Hydroxycholecalciferol as an antagonist of adverse corticosteroid effects on phosphate and calcium metabolism in man.

    abstract：:The present study was performed in 30 patients who needed steroid therapy: courses of triamcinolone or DTM 8-15 given orally lasted 30 days. In 15 of these patients glucoactive corticosteroids were administered in combination with 5 micrograms/day of 25OH-vitamin D3 (25OHD3). 47Calcium oral test and 99mTc-MDP kinetics...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348448

    authors： Nuti R,Vattimo A,Turchetti V,Righi G

    更新日期：1984-10-01 00:00:00

  • Thyrotropin-releasing hormone-like material in human retina.

    abstract：:Thyrotropin-releasing hormone (TRH)-like material was found in human retina obtained at autopsy from eyes used for corneal grafts. The TRH-like material was extracted with methanol and was found to be indistinguishable from synthetic TRH in its immunoreactivity and bioreactivity and in its proteolytic degradation by f...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348274

    authors： Martino E,Nardi M,Vaudagna G,Simonetti S,Cilotti A,Pinchera A,Venturi G,Seo H,Baschieri L

    更新日期：1980-07-01 00:00:00

  • Case of an ivory vertebra.

    abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03343770

    authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

    更新日期：2000-09-01 00:00:00

  • Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury.

    abstract：PURPOSE:Spinal cord injury (SCI) affects sexual health of both male and female, but little attention has been given to sexuality of SCI women. Similar to penile erection, vaginal lubrication represents a neurovascular event and then both denervation and vascular damage might contribute to its impairment. Nevertheless, ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01185-w

    authors： D'Andrea S,Castellini C,Paladino V,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

    更新日期：2020-07-01 00:00:00

  • Effects of PCSK9 inhibitors on LDL cholesterol, cardiovascular morbidity and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials.

    abstract：BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,meta分析

    doi：10.1007/s40618-019-01019-4

    authors： Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

    更新日期：2019-09-01 00:00:00

  • Long-term follow-up of patients with hyperthyroidism due to Graves' disease treated with methimazole. Comparison of usual treatment schedule with drug discontinuation vs continuous treatment with low methimazole doses: a retrospective study.

    abstract：:Antithyroid drugs may be proposed as the firstline therapy for hyperthyroidism due to Graves' disease since some patients undergo prolonged remission after drug withdrawal. On the other hand, some studies, though controversial, indicated that methimazole (MMI) has some immunomodulating activity. We retrospectively ana...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346433

    authors： Mazza E,Carlini M,Flecchia D,Blatto A,Zuccarini O,Gamba S,Beninati S,Messina M

    更新日期：2008-10-01 00:00:00

  • Different degrees of GH deficiency evidenced by GHRH+arginine test and IGF-I levels in adults with pituritary disease.

    abstract：:To verify if the entity of the peak GH responses to the GHRH+arginine (ARG) test is able to show different degree forms of GH deficiency (GHD), we linked these responses with the number of other anterior pituitary deficits. These anterior pituitary deficits were also related with IGF-I levels. To this purpose, we stud...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03345381

    authors： Aimaretti G,Corneli G,Di Somma C,Baldelli R,Gasco V,Rovere S,Migliaretti G,Colao A,Tamburrano G,Lombardi G,Ghigo E,Camanni F

    更新日期：2005-03-01 00:00:00

  • Control of circadian and episodic variations of adrenal androgens secretion in man.

    abstract：:The 24-h profiles of plasma cortisol (F), 11-beta-hydroxyandrostenedione (11OHAD), androstenedione (AD), dehydroisoandrosterone (DHEA) and testosterone (T) were obtained simultaneously in 11 normal males sampled at 15-min intervals. The data were submitted to a detailed quantitative analysis including the estimation o...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348129

    authors： Lejeune-Lenain C,Van Cauter E,Désir D,Beyloos M,Franckson JR

    更新日期：1987-06-01 00:00:00

  • Morning plasma free cortisol: inability to distinguish patients with mild Cushing syndrome from patients with pseudo-Cushing states.

    abstract：:Patients with Cushing syndrome have elevated 24 h urinary free cortisol excretion and loss of diurnal rhythm of plasma cortisol, however, morning total plasma cortisol concentrations are often similar to those of normal individuals. To test the hypothesis that an elevated morning plasma free cortisol could distinguish...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF03349791

    authors： Friedman TC,Yanovski JA

    更新日期：1995-10-01 00:00:00

  • UCP1 -3826 AG+GG genotypes, adiponectin, and leptin/adiponectin ratio in severe obesity.

    abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are well-recognized complications of obesity. This study was designed to evaluate the role of the UCP1 -3826 A>G polymorphism, adiponectin levels, leptin/adiponectin ratio (L/A), and main biochemical parameters in 102 unrelated se...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346500

    authors： Labruna G,Pasanisi F,Nardelli C,Tarantino G,Vitale DF,Bracale R,Finelli C,Genua MP,Contaldo F,Sacchetti L

    更新日期：2009-06-01 00:00:00

  • Endogenous testicular D-aspartic acid regulates gonadal aromatase activity in boar.

    abstract：:D-aspartic acid (D-Asp), aromatase enzyme activity and the putative D-Asp involvement on aromatase induction have been studied in the testis of mature boars. The peroxidase-antiperoxidase and the indirect immunofluorescence methods, applied to cryostat and paraffin sections, were used to evaluate D-Asp and aromatase d...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03344087

    authors： Lamanna C,Assisi L,Botte V,Di Fiore MM

    更新日期：2006-02-01 00:00:00

  • Meal intake similarly reduces circulating concentrations of octanoyl and total ghrelin in humans.

    abstract：UNLABELLED:ABSTRACT. Several data show that meal intake and nutritional status regulate circulating ghrelin concentrations in humans. Ghrelin mainly circulates in two different forms: octanoyl and des-octanoyl ghrelin. Most circulating ghrelin is des-octanoyl ghrelin which is considered inactive because it lacks endocr...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：

    authors： Lucidi P,Murdolo G,Di Loreto C,Parlanti N,De Cicco A,Ranchelli A,Fatone C,Taglioni C,Fanelli C,Santeusanio F,De Feo P

    更新日期：2004-05-01 00:00:00

  • Glucagon test in insulinoma: Is it useful?

    abstract：:Diagnosis of endogenous hyperinsulinism caused by insulinoma is based on confirmation of hypoglycemia during the symptoms associated to elevated insulin levels. Patients with insulinoma may demonstrate an excessive insulin response and subsequent hypoglycemia after 1 mg of glucagon iv injection. Glucagon test was perf...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.3275/7879

    authors： Felício JS,Martins CL,Mileo KB,Semer M,Kalinin L,Nery M,Machado MC,Liberman B

    更新日期：2012-06-01 00:00:00

  • The influence of high glucose and high insulin on mechanisms controlling cell cycle progression and arrest in mouse C2C12 myoblasts: the comparison with IGF-I effect.

    abstract：BACKGROUND:Myogenesis is susceptible to the availability of nutrients and humoral factors and suboptimal fetal environments affect the number of myofibers and muscle mass. AIM:We examined the mechanisms regulating cell cycle progression and arrest in skeletal myoblasts. MATERIALS AND METHODS:Mouse C2C12 myoblasts wer...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-013-0007-z

    authors： Grabiec K,Gajewska M,Milewska M,Błaszczyk M,Grzelkowska-Kowalczyk K

    更新日期：2014-03-01 00:00:00

  • Hypoproteinemia in acromegaly.

    abstract：:Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been analyzed for total pro...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03349317

    authors： Federspil G,Vettor R,Bossi A,Sicolo N

    更新日期：1979-04-01 00:00:00

  • Prevalence of metabolic syndrome in rural and urban Chinese population in Qingdao.

    abstract：AIMS:To investigate the prevalence of metabolic syndrome and its components in both rural and urban Chinese population. SUBJECTS AND METHODS:A population-based crosssectional survey was conducted in Qingdao, China in 2006 with 6100 Chinese aged 35-74 yr invited and 5355 who attended; 3357 subjects, 1562 urban (46.5%) ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/BF03346711

    authors： Zhao J,Pang ZC,Zhang L,Gao WG,Wang SJ,Ning F,Nan HR,Ren J,Qiao Q,Qingdao 2006 Diabetes Survey Group.

    更新日期：2011-06-01 00:00:00

  • Monitoring testosterone replacement therapy with transdermal gel: when and how?

    abstract：PURPOSE:Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage to bring and maintain serum T levels in the normal physiologic ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-019-01082-x

    authors： Sansone A,Sansone M,Selleri R,Schiavo A,Gianfrilli D,Pozza C,Zitzmann M,Lenzi A,Romanelli F

    更新日期：2019-12-01 00:00:00

  • Primary hypothyroidism-associated TSH-secreting pituitary adenoma/hyperplasia presenting as a bleeding nasal mass and extremely elevated TSH level.

    abstract：:A 41-year-old male with primary hypothyroidism and a huge TSH-secreting pituitary tumor presented with a bleeding nasal mass that was initially misdiagnosed as a paraganglioma. Other unique features of the case include lack of complaints related to hypothyroidism, an extremely elevated TSH level of 3474 mU/l, and a lo...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03343584

    authors： Ghannam NN,Hammami MM,Muttair Z,Bakheet SM

    更新日期：1999-06-01 00:00:00

  • Immunohistochemical detection of E-cadherin, alpha- and beta-catenins in papillary thyroid carcinoma.

    abstract：:E-cadherin and catenins play a major role in neoplastic cell behavior as a suppressor of invasion and/or metastasis. The aim of this study was to determine E-cadherin, alpha-catenin and beta-catenin expressions in papillary thyroid carcinoma (PTC) and to correlate the results of expression to initial clinicopathologic...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03345079

    authors： Kapran Y,Ozbey N,Molvalilar S,Sencer E,Dizdaroğlu F,Ozarmağan S

    更新日期：2002-07-01 00:00:00

  • Dietary fatty acids modify insulin secretion of rat pancreatic islet cells in vitro.

    abstract：:The type of dietary fat affects the action of insulin by changes induced in the fatty acid composition of cell membranes. Little is known, however, about the effects of dietary fatty acids on insulin secretion or the possible relation between the fatty acid composition of the membrane phospholipids and insulin secreti...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03344034

    authors： Tinahones FJ,Pareja A,Soriguer FJ,Gómez-Zumaquero JM,Cardona F,Rojo-Martínez G

    更新日期：2002-05-01 00:00:00

  • Serum levels of adipokines in gestational diabetes: a systematic review.

    abstract：OBJECTIVE:To determine the difference of serum levels of 10 adipokines (apelin, chemerin, fatty acid-binding protein-4, fibroblast growth factor-21, monocyte chemoattractant protein-1, nesfatin-1, omentin-1, resistin, vaspin, and visfatin) among women with gestational diabetes and healthy pregnant controls. MATERIALS ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-018-0973-2

    authors： Bellos I,Fitrou G,Pergialiotis V,Perrea DN,Daskalakis G

    更新日期：2019-06-01 00:00:00

  • The (-174) G/C polymorphism in the interleukin-6 gene is associated with risk of papillary thyroid carcinoma in Turkish patients.

    abstract：INTRODUCTION:Interleukins and cytokines play an important role in the pathogenesis of many cancers.We aimed to evaluate the interleukin (IL)-6 gene polymorphisms in patients with papillary thyroid carcinoma (PTC) and control subjects. MATERIAL AND METHODS:In this study, 42 patients with PTC and 340 healthy controls we...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346494

    authors： Ozgen AG,Karadeniz M,Erdogan M,Berdeli A,Saygili F,Yilmaz C

    更新日期：2009-06-01 00:00:00

  • Therapeutic effects of the selective farnesoid X receptor agonist obeticholic acid in a monocrotaline-induced pulmonary hypertension rat model.

    abstract：BACKGROUND:Activation of the farnesoid X receptor (FXR), a member of the nuclear receptor steroid superfamily, leads to anti-inflammatory and anti-fibrotic effects in several tissues, including the lung. We have recently demonstrated a protective effect of the farnesoid X receptor (FXR) agonist obeticholic acid (OCA) i...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-019-1009-2

    authors： Comeglio P,Filippi S,Sarchielli E,Morelli A,Cellai I,Corno C,Adorini L,Vannelli GB,Maggi M,Vignozzi L

    更新日期：2019-08-01 00:00:00

  • Acute effects of acylated and unacylated ghrelin on total and high molecular weight adiponectin inmorbidly obese subjects.

    abstract：BACKGROUND:Energy homeostasis and body weight are regulated by a highly complex network involving the brain, the digestive tract, and white adipose tissue (WAT). Knowledge about signaling pathways connecting digestive tract and WAT is limited. Gut hormone ghrelin and adipokine adiponectin are both decreased in obesity ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/BF03346709

    authors： Kiewiet RM,Hazell MJ,van Aken MO,van der Weerd K,Visser JA,Themmen AP,van der Lely AJ

    更新日期：2011-06-01 00:00:00

  • Association of comorbid depression, anxiety, and stress disorders with Type 2 diabetes in Bahrain, a country with a very high prevalence of Type 2 diabetes.

    abstract：:This study examined the association of depression, anxiety, and stress with Type 2 diabetes (T2DM) in Bahrain, an island-country with a very high prevalence of T2DM. This was a cross-sectional study involving administering Depression Anxiety Stress Scales (DASS)-21 structured depression, anxiety, and stress scale to 1...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03345642

    authors： Almawi W,Tamim H,Al-Sayed N,Arekat MR,Al-Khateeb GM,Baqer A,Tutanji H,Kamel C

    更新日期：2008-11-01 00:00:00

  • Pro-gamma-MSH levels in various disorders of pituitary-adrenal axis.

    abstract：:N-Terminal (1-76) portion of proopiomelanocortin (hNT) was measured in normals, Addison's, Nelson's, Cushing's disease, and in dexamethasone suppressible hyperaldosteronism (DSH) by using a specific homologous RIA. Mean basal immunoreactive hNT level was 94.2 +/- 6 pg/ml (mean +/- SE) in normal subjects. In Cushing's ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348575

    authors： Boscaro M,Giacomazzi P,Sonino N,Fallo F,Girard F,Bertagna X,Mantero F

    更新日期：1990-01-01 00:00:00

  • Puerperal breast feeding does not stimulate circulating opioids in humans.

    abstract：:ACTH, beta lipotropin (beta LPH), beta endorphin (beta EP), Prolactin (PRL) and Cortisol were measured in the first five days of puerperium at 9:00, before and 30 minutes after suckling, in 7 healthy lactating women. With the exception of PRL plasma levels which decline, although remaining at high concentrations durin...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350534

    authors： Genazzani AR,Facchinetti F,Parrini D,Petraglia F,La Rosa R,Puggioni R,D'Antona N

    更新日期：1982-11-01 00:00:00