Role of vitamin K on biochemical markers, bone mineral density, and fracture risk.

Abstract:

:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K played a significant role in human health beyond its well-established function in blood clotting. In fact, among the proteins known or suspected to be involved in bone and vascular biology there are several members of the vitamin K dependent or gamma-carboxyglutamic acid protein family. Based on the current evidence from epidemiologic and intervention studies, there are insufficient data to recommend a routine supplementation of vitamin K for optimal bone health. New experimental and placebo-controlled studies in humans should clarify our understanding of the role vitamin K plays in improving bone health.

journal_name

J Endocrinol Invest

authors

Francucci CM,Rilli S,Fiscaletti P,Boscaro M

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

24-8

issue

6 Suppl

eissn

0391-4097

issn

1720-8386

journal_volume

30

pub_type

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