Epileptic seizure after treatment with thiocolchicoside.

abstract：Background:The effect of continuous positive airway pressure (CPAP) on nasal symptoms in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) remains controversial. In addition, possible mechanism(s) remains unclear. Objective:To examine whether CPAP contributes to the onset and exacerbation of allergic rhi...

journal_title：Therapeutics and clinical risk management

authors： Yang Q,Li H,Wu W,Huang X,Tu B,Ma Y,Deng H,Li M,He H,Li C,Yang Y

更新日期：2018-08-24 00:00:00

abstract：:The treatment of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) positively changed since the introduction of anti-TNFα drugs. These treatments were shown to reduce the symptoms and signs of the diseases and improve the quality of life. However, a variable percentage of patients do not respond to anti-TNFα o...

journal_title：Therapeutics and clinical risk management

authors： Lubrano E,Perrotta FM

更新日期：2016-10-21 00:00:00

abstract：INTRODUCTION:Sepsis and septic shock are important causes of mortality in intensive care unit patients, hence early diagnosis and therapy are important in management of their treatment. The available information on sepsis patients is not enough to recommend or to discard the routine evaluation of triglyceride (TG) leve...

journal_title：Therapeutics and clinical risk management

authors： Cetinkaya A,Erden A,Avci D,Karagoz H,Karahan S,Basak M,Bulut K,Gencer V,Mutlu H

更新日期：2014-02-27 00:00:00

abstract：Purpose:To determine the early effects of intravitreal anti-VEGF and dexamethasone application on blood flow velocities in patients with retinal vein occlusions. Methods:The ophthalmic (OA) and the central retinal arteries (CRAs) of the affected and unaffected eyes of 21 patients with central retinal vein occlusion (C...

journal_title：Therapeutics and clinical risk management

authors： Ciloglu E,Yıldırım Celikdemir A

更新日期：2019-07-04 00:00:00

abstract：:In January 2012, glucarpidase (Voraxaze(®)) received approval from the US Food and Drug Administration for intravenous treatment of toxic plasma methotrexate concentrations due to impaired renal clearance. Methotrexate, an antifolate agent, has been used for over 60 years in the treatment of various cancers. High-dose...

journal_title：Therapeutics and clinical risk management

authors： Green JM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Internationally, there is a remarkable achievement in the areas of drug discovery, drug design, and clinical trials. New and efficient drug formulation techniques are widely available which have led to success in treatment of several diseases. Despite these achievements, large number of patients continue to ...

journal_title：Therapeutics and clinical risk management

authors： Abubakar AR,Ismail S,Rahman NI,Haque M

更新日期：2015-06-30 00:00:00

abstract：:The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

更新日期：2009-06-01 00:00:00

abstract：:Coronary and cerebrovascular atherothrombosis are the leading cause of mortality and morbidity worldwide. Novel antiplatelet agents have been established for the management of patients with clinically evident coronary atherothrombosis and are increasingly used in these patients. These agents, however, have shown limit...

journal_title：Therapeutics and clinical risk management

authors： Iannopollo G,Camporotondo R,De Ferrari GM,Leonardi S

更新日期：2014-05-02 00:00:00

abstract：Purpose:To analyze the treatment patterns of psoriatic arthritis (PSA) or ankylosing spondylitis (AS) patients under biological therapies and to evaluate in this population the health-care resource consumption and related costs. Patients and Methods:A retrospective analysis was performed on administrative databases of...

journal_title：Therapeutics and clinical risk management

authors： Perrone V,Giacomini E,Sangiorgi D,Andretta M,Menti AM,Naclerio M,Ritrovato D,Degli Esposti L

更新日期：2020-06-09 00:00:00

abstract：:The development of nonsteroidal anti-inflammatory drugs (NSAIDs) selective for cyclooxygenase (COX)-2 (named coxibs) has been driven by the aim of reducing the incidence of serious gastrointestinal (GI) adverse events associated with the administration of traditional (t) NSAIDs - mainly dependent on the inhibition of ...

journal_title：Therapeutics and clinical risk management

authors： Patrignani P,Tacconelli S,Capone ML

更新日期：2008-10-01 00:00:00

abstract：Background:Treatment-related problems (TRPs) may pose risks for patients if unaddressed. With the increased complexity of health care, it is important to target pharmacists' efforts to patients that are at high risk for TRPs. Objectives:The present study aimed to identify medications most commonly associated with TRPs...

journal_title：Therapeutics and clinical risk management

authors： Al-Taani GM,Al-Azzam SI,Alzoubi KH,Aldeyab MA

更新日期：2018-11-16 00:00:00

abstract：:Selectins mediate tethering and rolling of leukocytes to the vascular endothelium, the first adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a key role in the pathogenesis of common inflammatory skin disorders such as atopic dermatitis or psoriasis. As a consequence of their ...

journal_title：Therapeutics and clinical risk management

authors： Schön MP

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Pressure ulcers (PUs) in the sacral region can be a complication of surgical procedures performed in the lithotomy position. Previous reports have noted a difference between men and women in PU development related to the supine position, and body weight and body mass index (BMI) have been also described as k...

journal_title：Therapeutics and clinical risk management

authors： Mizuno J,Takahashi T

更新日期：2017-02-17 00:00:00

abstract：Purpose:Pharmacological errors are among the most common in the healthcare system. This study aimed to determine the level of safety of the pharmacotherapy process at the stage performed by nurses and midwives by indicating the key risk factors affecting patients' safety. Methods:A group of 1276 nurses and 136 midwive...

journal_title：Therapeutics and clinical risk management

authors： Witczak I,Uchmanowicz I,Tartaglia R,Rypicz Ł

更新日期：2020-11-04 00:00:00

abstract：:Purpose: This study aimed to assess the effect of intravenous dexmedetomidine (DEX) on sevoflurane EC50 for supraglottic airway device (SAD) insertion in spontaneously breathing morbidly obese patients. Patients and methods: Thirty-eight morbidly obese patients with a body mass index 40-57 kg/m2 who were scheduled for...

journal_title：Therapeutics and clinical risk management

authors： Wan L,Shao LJ,Liu Y,Wang HX,Xue FS,Tian M

更新日期：2019-05-03 00:00:00

abstract：Purpose:To compare running suture (RS) and interrupted suture (IS) of vesicourethral anastomosis (VUA) during open retropubic radical prostatectomy (RRP) on early urinary continence and extravasation. Patients and Methods:Single center analysis of 211 patients who underwent RRP performed by a single surgeon during 200...

journal_title：Therapeutics and clinical risk management

authors： Köhler N,El-Bandar N,Maxeiner A,Ralla B,Miller K,Busch J,Friedersdorff F

更新日期：2020-12-23 00:00:00

abstract：Background:Anesthesia and surgery may deteriorate liver function in patients with elevated liver enzyme levels; therefore, in these patients, choosing anesthetics with less hepatotoxicity is important. Methods:This retrospective study investigated the effect of total intravenous anesthesia (TIVA) versus inhalation ane...

journal_title：Therapeutics and clinical risk management

authors： Oh SK,Lim BG,Kim YS,Kim SS

更新日期：2020-04-05 00:00:00

abstract：:Objective: Intraventricular hemorrhage (IVH) is characterized by acute onset, rapid progression, and high disability and mortality rates. In this study, we investigated the clinical effect of external ventricular drainage combined with continuous lumbar drainage in IVH treatments. Methods: 114 patients with IVH treate...

journal_title：Therapeutics and clinical risk management

authors： Xia D,Jiang X,Li Z,Jin Y,Dai Y

更新日期：2019-05-30 00:00:00

abstract：:Therapy of soft tissue sarcomas represents an area of significant unmet need in oncology. Angiogenesis has been explored as a potential target both preclinically and clinically, with suggestions of activity. Pazopanib is a multitargeted tyrosine kinase inhibitor with prominent antiangiogenic effects. In a Phase II stu...

journal_title：Therapeutics and clinical risk management

authors： Cranmer LD,Loggers ET,Pollack SM

更新日期：2016-06-09 00:00:00

abstract：Purpose:We conducted this meta-analysis to evaluate the efficacy of hybrid grafts in anterior cruciate ligament reconstruction (ACLR). Methods:We performed an electronic search of the Cochrane Library, PubMed, Embase, and ScienceDirect from the inception of these databases to February 2018, based on the terms "anterio...

journal_title：Therapeutics and clinical risk management

authors： Wang L,Cao JG,Liu J

更新日期：2019-03-14 00:00:00

abstract：:A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act) cycle was used for continuous quality improvement. The proportio...

journal_title：Therapeutics and clinical risk management

authors： Zhu LL,Xu LC,Wang HQ,Jin JF,Wang HF,Zhou Q

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this review was to test contraceptive efficacy, cycle control, tolerability, and acceptability as found in the non-comparative studies with NuvaRing((R)) by those found in the randomized trials comparing NuvaRing and combined oral contraceptives (COCs). All large non-comparative studies and all relevant...

journal_title：Therapeutics and clinical risk management

authors： Roumen FJ

更新日期：2008-04-01 00:00:00

abstract：Background:Despite the considerable experience gained thus far using endoscopic technologies, the role of total endoscopic thyroidectomy (ET) for papillary thyroid cancer (PTC) remains controversial. We conducted a systematic review and meta-analysis to investigate the safety and effectiveness of total ET compared with...

journal_title：Therapeutics and clinical risk management

authors： Chen C,Huang S,Huang A,Jia Y,Wang J,Mao M,Zhou J,Wang L

更新日期：2018-12-05 00:00:00

abstract：AIM:To evaluate the efficacy of glycopyrrolate oral solution (1 mg/5 mL) in managing problem drooling associated with cerebral palsy and other neurologic conditions. METHOD:Thirty-eight patients aged 3-23 years weighing at least 27 lb (12.2 kg) with severe drooling (clothing damp 5-7 days/week) were randomized to glyc...

journal_title：Therapeutics and clinical risk management

authors： Zeller RS,Lee HM,Cavanaugh PF,Davidson J

更新日期：2012-01-01 00:00:00

abstract：:We present here the case of a 33-year-old Chinese female patient with synchronous double primary malignant tumors (chronic myeloid leukemia [CML] and classic Hodgkin lymphoma). This patient was admitted to our hospital because of bilateral cervical lymph node enlargement and recurrent fever for 2 weeks. The complete b...

journal_title：Therapeutics and clinical risk management

authors： Liu Z,Li S,Bai O

更新日期：2017-09-05 00:00:00

abstract：Introduction:Preservation of endodontically treated teeth (ETT) depends upon several patient-related and operator-related factors. The objectives of this study were to assess the effects of different types of coronal restoration and delayed placement on ETT survival. Methods:Data on dates of root canal treatment (RCT)...

journal_title：Therapeutics and clinical risk management

authors： Sadaf D

更新日期：2020-02-21 00:00:00

abstract：BACKGROUND AND AIMS:The aims of this study were to explore the correlation between chronic hepatitis B virus (HBV) drug-resistant mutation profiles and the efficacy of nucleoside analog rescue therapy in patients with initial antiviral treatment failure. PATIENTS AND METHODS:Patients with initial antiviral therapy fai...

journal_title：Therapeutics and clinical risk management

authors： Liang LB,Chen LL,Chen EQ,Liao J,Tang H

更新日期：2015-03-12 00:00:00

abstract：:A formal risk assessment for identifying high-risk patients is essential in clinical practice and promoted in guidelines for the management of anterior acute myocardial infarction. In this study, we sought to evaluate the performance of different machine learning models in predicting the 1-year mortality rate of anter...

journal_title：Therapeutics and clinical risk management

authors： Li YM,Jiang LC,He JJ,Jia KY,Peng Y,Chen M

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:This study aims to investigate differences between continuous epidural infusion (CEI) and programmed intermittent epidural bolus (IEB) analgesia for the Chinese parturients undergoing spontaneous delivery and to approach their safety to parturients and neonates. METHODS:Two hundred healthy American Society ...

journal_title：Therapeutics and clinical risk management

authors： Lin Y,Li Q,Liu J,Yang R,Liu J

更新日期：2016-07-14 00:00:00

abstract：:Erectile dysfunction (ED) is often perceived by both patients and sexual partners as a serious problem that can jeopardize quality of life, psychosocial or emotional well-being, and the partnership in the long term. Since their introduction, oral phosphodiesterase type 5 inhibitors (PDE5Is) have been found to be highl...

journal_title：Therapeutics and clinical risk management

authors： Cho MC,Paick JS

更新日期：2014-05-14 00:00:00