Safety Assessment of the Pharmacotherapy Process at the Nurse and Midwife Level - An Observational Study.

abstract：Purpose:To compare running suture (RS) and interrupted suture (IS) of vesicourethral anastomosis (VUA) during open retropubic radical prostatectomy (RRP) on early urinary continence and extravasation. Patients and Methods:Single center analysis of 211 patients who underwent RRP performed by a single surgeon during 200...

journal_title：Therapeutics and clinical risk management

authors： Köhler N,El-Bandar N,Maxeiner A,Ralla B,Miller K,Busch J,Friedersdorff F

更新日期：2020-12-23 00:00:00

abstract：:The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To investigate the reactivation of the hepatitis B virus (HBV) following transarterial chemoembolization (TACE) in Chinese hepatocellular carcinoma (HCC) patients with low serum HBV DNA level, and to analyze the factors related to HBV reactivation in HCC patients with low serum HBV DNA level. METHODS:From No...

journal_title：Therapeutics and clinical risk management

authors： Shao W,Zhang F,Cong N,Li J,Song J

更新日期：2015-09-07 00:00:00

abstract：:Therapy of soft tissue sarcomas represents an area of significant unmet need in oncology. Angiogenesis has been explored as a potential target both preclinically and clinically, with suggestions of activity. Pazopanib is a multitargeted tyrosine kinase inhibitor with prominent antiangiogenic effects. In a Phase II stu...

journal_title：Therapeutics and clinical risk management

authors： Cranmer LD,Loggers ET,Pollack SM

更新日期：2016-06-09 00:00:00

abstract：:Japanese encephalitis (JE) is one of severe viral encephalitis that affects individuals in Asia, western Pacific countries, and northern Australia. Although 67,900 JE cases have been estimated among 24 JE epidemic countries annually, only 10,426 have been reported in 2011. With the establishment of JE surveillance and...

journal_title：Therapeutics and clinical risk management

authors： Wang H,Liang G

更新日期：2015-03-19 00:00:00

abstract：:Hemodialysis (HD) patients are more susceptible to infective endocarditis (IE) due to the increased risk of bacterial invasion through intravascular access. However, it remains unclear whether the causative organisms and outcomes of IE in HD patients differ from those in non-HD patients. This study clarified the diffe...

journal_title：Therapeutics and clinical risk management

authors： Hsiao CC,Weng CH,Li YJ,Wu HH,Chen YC,Chen YM,Hsu HH,Tian YC

更新日期：2017-05-24 00:00:00

abstract：:Use of non-vitamin K antagonist oral anticoagulants is spreading in the real world. Despite that, a strong need for antidotes/reversal agents is still reported by several physicians. Idarucizumab is a humanized monoclonal antibody fragment that binds specifically to dabigatran. Idarucizumab was approved in 2015 by the...

journal_title：Therapeutics and clinical risk management

authors： Proietti M,Boriani G

更新日期：2018-08-22 00:00:00

abstract：Background:Despite the considerable experience gained thus far using endoscopic technologies, the role of total endoscopic thyroidectomy (ET) for papillary thyroid cancer (PTC) remains controversial. We conducted a systematic review and meta-analysis to investigate the safety and effectiveness of total ET compared with...

journal_title：Therapeutics and clinical risk management

authors： Chen C,Huang S,Huang A,Jia Y,Wang J,Mao M,Zhou J,Wang L

更新日期：2018-12-05 00:00:00

abstract：:The advent of exponential growth of novel agents tested and approved for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) has brought about a need for understanding of the mechanism of action, side-effects, and clinical efficacy of these drugs as they relate to these patients. Thi...

journal_title：Therapeutics and clinical risk management

authors： Patel NK,Finianos A,Whitaker KD,Aragon-Ching JB

更新日期：2014-08-16 00:00:00

abstract：:Background: Endoscopic sinus surgery (ESS) has been the definitive treatment for chronic rhinosinusitis (CRS), but the complications caused perioperatively may affect patients' quality of life (QoL). This study aims to evaluate the effects of enhanced recovery after surgery (ERAS) on improving perioperative QoL in ESS...

journal_title：Therapeutics and clinical risk management

authors： Wu X,Kong W,Zhu Q,Wang W,Xu H,Zhou S,Yang Q

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:Narcolepsy is a lifelong, rare neurological sleep disorder characterized by chronic, excessive attacks of daytime sleepiness. This disease is often extremely incapacitating, interfering with every aspect of life, in work and social settings. OBJECTIVE:The purpose of this study is to specify the treatment co...

journal_title：Therapeutics and clinical risk management

authors： Maresova P,Novotny M,Klímová B,Kuča K

更新日期：2016-11-18 00:00:00

abstract：PURPOSE:To report two cases of chronic postoperative cystoid macular edema, resistant to topical therapy, treated with consecutive intravitreal injections of ketorolac tromethamine. METHODS:Four daily intravitreal injections of 500 μg/0.05 mL of ketorolac were given to each patient. Complete clinical examination and O...

journal_title：Therapeutics and clinical risk management

authors： Tsilimbaris MK,Tsika C,Kymionis GD

更新日期：2016-02-12 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative, dopamine deficiency disorder. The main therapeutic strategies for PD treatment relies on dopamine precursors (levodopa), inhibition of dopamine metabolism (monoamine oxidase [MAO] B and catechol-O-methyl transferase inhibitors), and dopamine receptor agonist...

journal_title：Therapeutics and clinical risk management

authors： Lecht S,Haroutiunian S,Hoffman A,Lazarovici P

更新日期：2007-06-01 00:00:00

abstract：:Hepatoid adenocarcinoma of the stomach (HAS) is a rare subgroup of gastric cancer (GC). Morphologically, this tumor exhibits both adenocarcinomatous and hepatocellular differentiation, and most tumors show immunohistochemical staining for alpha-fetoprotein (AFP) or elevated AFP serum levels. The diagnosis of HAS is fr...

journal_title：Therapeutics and clinical risk management

authors： Søreide JA

更新日期：2019-12-23 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is highly endemic in certain regions including the People's Republic of China and Southeast Asia. Its etiology is unique and multifactorial, involving genetic background, epigenetic, and environment factors, including Epstein-Barr virus (EBV) infection. The presence of EBV in all tumor c...

journal_title：Therapeutics and clinical risk management

authors： Hutajulu SH,Kurnianda J,Tan IB,Middeldorp JM

更新日期：2014-09-05 00:00:00

abstract：BACKGROUND:Pressure ulcers (PUs) in the sacral region can be a complication of surgical procedures performed in the lithotomy position. Previous reports have noted a difference between men and women in PU development related to the supine position, and body weight and body mass index (BMI) have been also described as k...

journal_title：Therapeutics and clinical risk management

authors： Mizuno J,Takahashi T

更新日期：2017-02-17 00:00:00

abstract：:Objective: Intraventricular hemorrhage (IVH) is characterized by acute onset, rapid progression, and high disability and mortality rates. In this study, we investigated the clinical effect of external ventricular drainage combined with continuous lumbar drainage in IVH treatments. Methods: 114 patients with IVH treate...

journal_title：Therapeutics and clinical risk management

authors： Xia D,Jiang X,Li Z,Jin Y,Dai Y

更新日期：2019-05-30 00:00:00

abstract：:Chordomas are rare, locally aggressive skull base neoplasms known for local recurrence and not-infrequent treatment failure. Current evidence supports the role of maximal safe surgical resection. In addition to open skull-base approaches, the endoscopic endonasal approach to clival chordomas has been reported with fav...

journal_title：Therapeutics and clinical risk management

authors： Di Maio S,Yip S,Al Zhrani GA,Alotaibi FE,Al Turki A,Kong E,Rostomily RC

更新日期：2015-05-26 00:00:00

abstract：:The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the alpha(1a) and alpha(1d) adrenergic receptor subtypes. The oral-controlled absorption system (OCAS((R))) represents a drug delivery refinement that incorporates a matrix of gel-f...

journal_title：Therapeutics and clinical risk management

authors： Neill MG,Shahani R,Zlotta AR

更新日期：2008-02-01 00:00:00

abstract：Background:The effect of continuous positive airway pressure (CPAP) on nasal symptoms in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) remains controversial. In addition, possible mechanism(s) remains unclear. Objective:To examine whether CPAP contributes to the onset and exacerbation of allergic rhi...

journal_title：Therapeutics and clinical risk management

authors： Yang Q,Li H,Wu W,Huang X,Tu B,Ma Y,Deng H,Li M,He H,Li C,Yang Y

更新日期：2018-08-24 00:00:00

abstract：:Behçet's disease is an autoinflammatory vasculitis of unknown origin characterized by recurrent oral and genital ulcers, uveitis, arthritis and skin lesions. Additionally, involvement of the gastrointestinal tract, central nervous system and large vessels may occur. The disease is prevalent in countries along the anci...

journal_title：Therapeutics and clinical risk management

authors： van Daele PL,Kappen JH,van Hagen PM,van Laar JA

更新日期：2009-04-01 00:00:00

abstract：:Cetuximab is a monoclonal antibody able to inhibit and to degrade the transmembrane receptor Her-1, also known as epidermal growth factor receptor (EGFR). The inhibition of EGFR is of major importance since the receptor influences many important tumor cell activities including tumor growth, neo-angiogenesis, inhibitio...

journal_title：Therapeutics and clinical risk management

authors： Merlano M,Occelli M

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:The significance of early ischemic changes (EIC) on computed tomography (CT) within 3 hours after stroke onset remains controversial. The semi-quantitative Alberta Stroke Program Early CT Score (ASPECTS) is found to have prognostic value in early stroke. This study assesses factors associated with the presen...

journal_title：Therapeutics and clinical risk management

authors： Thomassen L,Waje-Andreassen U,Naess H

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Hypertension is a highly prevalent risk factor for cardiovascular disease in patients with type 1 diabetes mellitus. Elevated blood pressure (BP) promotes the development and progression of microvascular complications, eg, nephropathy and retinopathy. The purpose of this study was to identify and detect earl...

journal_title：Therapeutics and clinical risk management

authors： Shalaby NM,Shalaby NM

更新日期：2015-10-05 00:00:00

abstract：:Allergic rhinitis and urticaria are common allergic diseases that may have a major negative impact on patients' quality of life. Bilastine, a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. This agent does not interact with ...

journal_title：Therapeutics and clinical risk management

authors： Wang XY,Lim-Jurado M,Prepageran N,Tantilipikorn P,Wang de Y

更新日期：2016-04-13 00:00:00

abstract：:Purpose: This study aimed to assess the effect of intravenous dexmedetomidine (DEX) on sevoflurane EC50 for supraglottic airway device (SAD) insertion in spontaneously breathing morbidly obese patients. Patients and methods: Thirty-eight morbidly obese patients with a body mass index 40-57 kg/m2 who were scheduled for...

journal_title：Therapeutics and clinical risk management

authors： Wan L,Shao LJ,Liu Y,Wang HX,Xue FS,Tian M

更新日期：2019-05-03 00:00:00

abstract：:Cerebral palsy (CP) is the main cause of physical disability in childhood and is an important health issue that has a strong socioeconomic impact. There is no effective treatment for CP and therapeutic approaches report only partial benefits for affected people. In this study we assessed the effects of growth hormone ...

journal_title：Therapeutics and clinical risk management

authors： Devesa J,Alonso B,Casteleiro N,Couto P,Castañón B,Zas E,Reimunde P

更新日期：2011-01-01 00:00:00

abstract：Background:Cardiovascular diseases (CVDs) are the main complication leading to morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). There is a large amount of evidence to support the use of lipid-lowering therapy (LLT) for the prevention of CVD. This study aimed to assess the effectiveness and p...

journal_title：Therapeutics and clinical risk management

authors： Elnaem MH,Mohamed MHN,Huri HZ,Shah ASM

更新日期：2019-01-18 00:00:00

abstract：:Soft tissue sarcomas (STSs) are a group of rare tumors accounting for less than 1% of all adult malignant tumors, a heterogeneous group of more than 50 histological subtypes. Five percent to 30% of STS patients experience local recurrence and 10%-38% present with clinically detectable metastases. Doxorubicin either al...

journal_title：Therapeutics and clinical risk management

authors： Nakamura T,Matsumine A,Sudo A

更新日期：2016-01-13 00:00:00

abstract：:Poorly controlled asthma is currently treated by adding or removing asthma medication in a stepwise fashion to try and improve symptoms and maintain lung function. It is becoming apparent that asthma exacerbations are independent of asthma control and severity, and that the simple method of using rescue courses of cor...

journal_title：Therapeutics and clinical risk management

authors： Shaw DE,Green RH,Bradding P

更新日期：2005-12-01 00:00:00