Abstract:
INTRODUCTION:Sepsis and septic shock are important causes of mortality in intensive care unit patients, hence early diagnosis and therapy are important in management of their treatment. The available information on sepsis patients is not enough to recommend or to discard the routine evaluation of triglyceride (TG) levels at the onset of sepsis. The aim of this study was to investigate the association of hypertriglyceridemia and clinical outcome (or mortality) in patients with severe sepsis. MATERIALS AND METHODS:Between January 1 and December 31, 2011, a total of 84 patients with sepsis from the intensive internal care unit at the Kayseri Training and Research Hospital, Kayseri, Turkey, were investigated retrospectively. Sepsis was defined according to the American College of Chest Physicians/Society of Critical Care Medicine/European Society of Intensive Care Medicine consensus conference definitions. For each patient, survival was recorded at the end of the last day of hospitalization as dead or alive. The TG values were taken retrospectively from the records, which were performed routinely for each patient with sepsis at the time of diagnosis. TG >150 mg/dL was considered as hypertriglyceridemia. RESULTS:The percentages of male and female patients were 44% and 56%, respectively. The mean age of patients was 71.49±11.071 years. The percentage of patients with TG values more than 150 mg/dL was 81% (25/31) in the non-survivor group and 19% (6/31) in the survivor group. There was a significant difference regarding TG values between groups (P=0.039). DISCUSSION:It was observed in this study that patients in the intensive care unit with sepsis had high TG levels. We also observed that the TG level >150 mg/dL at 0 hour (onset of sepsis) was a significant predictive marker of sepsis mortality rate. The contribution of hypertriglyceridemia to mortality might be modest compared to increase in severity of illness, but, nevertheless, these simple measurements represent a potential therapeutic target in sepsis.
journal_name
Ther Clin Risk Managjournal_title
Therapeutics and clinical risk managementauthors
Cetinkaya A,Erden A,Avci D,Karagoz H,Karahan S,Basak M,Bulut K,Gencer V,Mutlu Hdoi
10.2147/TCRM.S57791subject
Has Abstractpub_date
2014-02-27 00:00:00pages
147-50eissn
1176-6336issn
1178-203Xpii
tcrm-10-147journal_volume
10pub_type
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
doi:10.2147/TCRM.S84789
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journal_title:Therapeutics and clinical risk management
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journal_title:Therapeutics and clinical risk management
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abstract::[This corrects the article on p. 741 in vol. 14, PMID: 29719401.]. ...
journal_title:Therapeutics and clinical risk management
pub_type: 已发布勘误
doi:10.2147/TCRM.S177217
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/tcrm.s1997
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S30135
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S33674
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S170642
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S137144
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S107808
更新日期:2016-06-24 00:00:00
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
doi:10.2147/TCRM.S145039
更新日期:2018-05-31 00:00:00
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/tcrm.2007.3.2.213
更新日期:2007-06-01 00:00:00
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S143247
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/tcrm.s3694
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
doi:10.2147/TCRM.S84792
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
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journal_title:Therapeutics and clinical risk management
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更新日期:2018-10-08 00:00:00
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journal_title:Therapeutics and clinical risk management
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更新日期:2018-04-17 00:00:00
abstract:AIM:The aim of this study was to evaluate the efficacy of, and patients' subjective responses to, periodontal ligament (PDL) anesthetic injection compared to traditional local-anesthetic infiltration injection for the nonsurgical extraction of one posterior maxillary permanent tooth. MATERIALS AND METHODS:All patients...
journal_title:Therapeutics and clinical risk management
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更新日期:2017-10-06 00:00:00
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
doi:10.2147/TCRM.S175215
更新日期:2018-10-17 00:00:00
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章
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journal_title:Therapeutics and clinical risk management
pub_type: 杂志文章,评审
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