Relevance of the Weber effect in contemporary pharmacovigilance of oncology drugs.

abstract：:[This corrects the article on p. 741 in vol. 14, PMID: 29719401.]. ...

journal_title：Therapeutics and clinical risk management

authors：

更新日期：2018-06-26 00:00:00

abstract：OBJECTIVE:International travelers from non-endemic areas are at high risk of contracting malaria due to their lack of immunity. Prevention is therefore of outmost importance and is achieved through effective and safe chemoprophylaxis, which reduces the risk of fatal disease. Among the various antimalarial drugs availab...

journal_title：Therapeutics and clinical risk management

authors： Nicosia V,Colombo G,Consentino M,Di Matteo S,Mika F,De Sanctis S,Ratti S,Vinci M

更新日期：2008-10-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a chronic disease that affects 14.2% of the US adult population. Despite being widespread, little is known about the etiology of CRS. Treatment has been symptomatic and focused on relieving symptoms. Recent investigations into causes of CRS have revealed that most CRS patients have an e...

journal_title：Therapeutics and clinical risk management

authors： Kern EB,Sherris D,Stergiou AM,Katz LM,Rosenblatt LC,Ponikau J

更新日期：2007-06-01 00:00:00

abstract：:Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage. AKs have historically been characterized as being "precancerous"; however, now it is considered by many author...

journal_title：Therapeutics and clinical risk management

authors： Skroza N,Bernardini N,Proietti I,Potenza C

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND AND AIMS:The aims of this study were to explore the correlation between chronic hepatitis B virus (HBV) drug-resistant mutation profiles and the efficacy of nucleoside analog rescue therapy in patients with initial antiviral treatment failure. PATIENTS AND METHODS:Patients with initial antiviral therapy fai...

journal_title：Therapeutics and clinical risk management

authors： Liang LB,Chen LL,Chen EQ,Liao J,Tang H

更新日期：2015-03-12 00:00:00

abstract：:The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:A meta-analysis was conducted to evaluate the clinical outcomes, complications, reoperation rates, and late neurological deterioration between anterior decompression and fusion (ADF) and laminoplasty (LAMP) in the treatment of multilevel cervical ossification of the posterior longitudinal ligament (OPLL). METH...

journal_title：Therapeutics and clinical risk management

authors： Liu W,Hu L,Chou PH,Liu M,Kan W,Wang J

更新日期：2016-04-26 00:00:00

abstract：BACKGROUND/PURPOSE:In-hospital mortality rate of acute ischemic stroke patients remains between 3% and 18%. For improving the quality of stroke care, we investigated the factors that contribute to the risk of in-hospital mortality in acute ischemic stroke patients. MATERIALS AND METHODS:Between January 1, 2007, and De...

journal_title：Therapeutics and clinical risk management

authors： Ong CT,Wong YS,Wu CS,Su YH

更新日期：2016-06-29 00:00:00

abstract：BACKGROUND:Artemether-lumefantrine (AL) has been used as a first-line treatment for uncomplicated Plasmodium falciparum malaria in Ethiopia since 2004. Antimalarial drug resistance is one of the major obstacles for malaria control and curtails the lifespan of several drugs. Thus, continued monitoring of the efficacy of...

journal_title：Therapeutics and clinical risk management

authors： Deressa T,Seid ME,Birhan W,Aleka Y,Tebeje BM

更新日期：2017-02-16 00:00:00

abstract：:A formal risk assessment for identifying high-risk patients is essential in clinical practice and promoted in guidelines for the management of anterior acute myocardial infarction. In this study, we sought to evaluate the performance of different machine learning models in predicting the 1-year mortality rate of anter...

journal_title：Therapeutics and clinical risk management

authors： Li YM,Jiang LC,He JJ,Jia KY,Peng Y,Chen M

更新日期：2020-01-09 00:00:00

abstract：:The management of acute episodes in schizophrenia is frequently initiated in the psychiatric emergency department and requires rapid intervention to relieve distress and psychiatric symptoms. Both non-pharmacological and pharmacological interventions are needed to calm the patient and prevent potential harm to the pat...

journal_title：Therapeutics and clinical risk management

authors： Nuss P,Hummer M,Tessier C

更新日期：2007-03-01 00:00:00

abstract：:The treatment of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) positively changed since the introduction of anti-TNFα drugs. These treatments were shown to reduce the symptoms and signs of the diseases and improve the quality of life. However, a variable percentage of patients do not respond to anti-TNFα o...

journal_title：Therapeutics and clinical risk management

authors： Lubrano E,Perrotta FM

更新日期：2016-10-21 00:00:00

abstract：BACKGROUND:This retrospective cohort study evaluated whether manual lymphatic drainage (MLD) therapy increases the risk of recurrence of breast cancer. METHODS:We analyzed 1,106 women who were diagnosed with stage 0-3 breast cancer between 2007 and 2011 and experienced remission after surgery and adjuvant therapy. The...

journal_title：Therapeutics and clinical risk management

authors： Hsiao PC,Liu JT,Lin CL,Chou W,Lu SR

更新日期：2015-02-27 00:00:00

abstract：:Opioid analgesics are essential in the treatment of moderate to severe cancer-related pain. Opioids are also recognized as important in the management of other severe, persistent refractory painful conditions, such as sickle cell disease and arthritis. In the clinical practice of pain management, stable opioid dosing ...

journal_title：Therapeutics and clinical risk management

authors： Weinstein SM

更新日期：2009-02-01 00:00:00

abstract：:Procarbazine HCl is a 'nonclassical' oral alkylating anticancer agent that was first synthesized in the late 1950s. It has been used in the treatment of many cancers, but its main use is in the treatment of Hodgkin's lymphoma and brain tumors and, to a lesser extent, Non-Hodgkin's lymphoma and primary central nervous ...

journal_title：Therapeutics and clinical risk management

authors： Armand JP,Ribrag V,Harrousseau JL,Abrey L

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Adverse drug reactions are important determinants of inpatient and outpatient morbidity. Thiocolchicoside is a semisynthetic derivate of naturally occurring colchicoside, which is largely used in humans as a centrally acting muscle relaxant. Epileptic seizures after thiocolchicoside intake have been reported...

journal_title：Therapeutics and clinical risk management

authors： Giavina-Bianchi P,Giavina-Bianchi M,Tanno LK,Ensina LF,Motta AA,Kalil J

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Narcolepsy is a lifelong, rare neurological sleep disorder characterized by chronic, excessive attacks of daytime sleepiness. This disease is often extremely incapacitating, interfering with every aspect of life, in work and social settings. OBJECTIVE:The purpose of this study is to specify the treatment co...

journal_title：Therapeutics and clinical risk management

authors： Maresova P,Novotny M,Klímová B,Kuča K

更新日期：2016-11-18 00:00:00

abstract：:Hyperphosphatemia is an inevitable consequence of end stage chronic kidney disease and is present in the majority of dialysis patients. Recent observational data has associated hyperphosphatemia with increased cardiovascular mortality among dialysis patients. Dietary restriction of phosphate and current dialysis presc...

journal_title：Therapeutics and clinical risk management

authors： Mohammed IA,Hutchison AJ

更新日期：2008-10-01 00:00:00

abstract：:Staphylococcus aureus bacteremia is a common disease with a high risk of mortality and complications. An increasing proportion of cases are methicillin-resistant S.aureus (MRSA), and methicillin-resistance is being observed from both community-acquired bacteremias and in healthcare-associated infections. The duration ...

journal_title：Therapeutics and clinical risk management

authors： Bamberger DM

更新日期：2007-08-01 00:00:00

abstract：:Selectins mediate tethering and rolling of leukocytes to the vascular endothelium, the first adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a key role in the pathogenesis of common inflammatory skin disorders such as atopic dermatitis or psoriasis. As a consequence of their ...

journal_title：Therapeutics and clinical risk management

authors： Schön MP

更新日期：2005-09-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is highly endemic in certain regions including the People's Republic of China and Southeast Asia. Its etiology is unique and multifactorial, involving genetic background, epigenetic, and environment factors, including Epstein-Barr virus (EBV) infection. The presence of EBV in all tumor c...

journal_title：Therapeutics and clinical risk management

authors： Hutajulu SH,Kurnianda J,Tan IB,Middeldorp JM

更新日期：2014-09-05 00:00:00

abstract：:Eslicarbazepine is a new dibenzazepine antiepileptic agent. It is a high affinity antagonist of the voltage-gated sodium channel. It is closely related to both carbamazepine and oxcarbazepine. Eslicarbazepine has similar affinity to inactivated sodium channels (channels in just activated neurons) as carbamazepine, and...

journal_title：Therapeutics and clinical risk management

authors： Brown ME,El-Mallakh RS

更新日期：2010-04-15 00:00:00

abstract：:Trichosporon asahii is an emerging opportunistic pathogen that is life-threatening particularly for immunosuppressed patients. Only a few studies have described Trichosporon infection in kidney transplant recipients. This study reports a 67-year-old male kidney transplant recipient who developed fatal fungemia and pne...

journal_title：Therapeutics and clinical risk management

authors： Yang MF,Gao HN,Li LJ

更新日期：2014-09-30 00:00:00

abstract：:Recovery after total hip arthroplasty (THA) is influenced by several psychological aspects, such as depression, anxiety, resilience, and personality traits. We hypothesized that preoperative depression impedes early functional outcome after THA (primary outcome measure). Additional objectives were perioperative change...

journal_title：Therapeutics and clinical risk management

authors： Benditz A,Jansen P,Schaible J,Roll C,Grifka J,Götz J

更新日期：2017-02-21 00:00:00

abstract：INTRODUCTION:Renal cell carcinoma (RCC) represents 2%-3% of all cancers in adults, and its pathogenesis is mainly related to altered cellular response to hypoxia. Lenvatinib, a novel multitarget tyrosine kinase inhibitor (TKI), represents a therapeutic option, in combination with mammalian target of rapamycin (mTOR) in...

journal_title：Therapeutics and clinical risk management

authors： Leonetti A,Leonardi F,Bersanelli M,Buti S

更新日期：2017-06-30 00:00:00

abstract：:Experimental data indicate that several pharmacological agents that have long been used for the management of various diseases unrelated to cancer exhibit profound in vitro and in vivo anticancer activity. This is of major clinical importance, since it would possibly aid in reassessing the therapeutic use of currently...

journal_title：Therapeutics and clinical risk management

authors： Papanagnou P,Baltopoulos P,Tsironi M

更新日期：2015-05-18 00:00:00

abstract：:Hemodialysis (HD) patients are more susceptible to infective endocarditis (IE) due to the increased risk of bacterial invasion through intravascular access. However, it remains unclear whether the causative organisms and outcomes of IE in HD patients differ from those in non-HD patients. This study clarified the diffe...

journal_title：Therapeutics and clinical risk management

authors： Hsiao CC,Weng CH,Li YJ,Wu HH,Chen YC,Chen YM,Hsu HH,Tian YC

更新日期：2017-05-24 00:00:00

abstract：BACKGROUND:The aim of this open-label, randomized, parallel-group pilot study was to evaluate the efficacy of cefditoren pivoxil and levofloxacin in terms of speed of reduction in inflammatory parameters, clinical recovery, and microbiological eradication. METHODS:Forty eligible patients with acute exacerbation of chr...

journal_title：Therapeutics and clinical risk management

authors： Blasi F,Tarsia P,Mantero M,Morlacchi LC,Piffer F

更新日期：2013-01-01 00:00:00

abstract：Background:Hyperparathyroidism is a frequent endocrine disorder with variable clinical manifestations and outcomes. We aimed to evaluate clinical presentations, management and outcomes of hyperparathyroidism. Methods:A retrospective study was conducted to include all patients presented with hyperparathyroidism between...

journal_title：Therapeutics and clinical risk management

authors： Al-Thani H,El-Matbouly M,Al-Sulaiti M,Asim M,Majzoub A,Tabeb A,El-Menyar A

更新日期：2018-07-31 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory skin disease that can have a significant impact on the quality of life of those who are afflicted. Recent advances in the understanding of the pathophysiology of psoriasis have led to the development of new, genetically engineered, targeted therapies for this disease. Among...

journal_title：Therapeutics and clinical risk management

authors： Alwawi EA,Mehlis SL,Gordon KB

更新日期：2008-04-01 00:00:00