Clinical use of lenvatinib in combination with everolimus for the treatment of advanced renal cell carcinoma.

abstract：:Antimicrobial resistant bacteria are an increasing concern due to the resulting increase in morbidity, mortality, and health-care costs associated with the administration of inadequate or delayed antimicrobial therapy. The implications of inadequate antimicrobial therapy in complicated skin and skin structure infectio...

journal_title：Therapeutics and clinical risk management

authors： Barbour A,Derendorf H

更新日期：2010-10-05 00:00:00

abstract：:Hepatoid adenocarcinoma of the stomach (HAS) is a rare subgroup of gastric cancer (GC). Morphologically, this tumor exhibits both adenocarcinomatous and hepatocellular differentiation, and most tumors show immunohistochemical staining for alpha-fetoprotein (AFP) or elevated AFP serum levels. The diagnosis of HAS is fr...

journal_title：Therapeutics and clinical risk management

authors： Søreide JA

更新日期：2019-12-23 00:00:00

abstract：:Background: To report our experience with retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys. Methods: We retrospectively reviewed the medical records of 7 patients who underwent retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy at our inst...

journal_title：Therapeutics and clinical risk management

authors： Qin J,Wang P,Jing T,Kong D,Ye S,Xia D,Wang S

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Acute diarrhea is the major cause of child morbidity and mortality in low-income nations. It is the second most common cause of death among children <5 years of age globally. The indispensable role of community pharmacists is clearly observed in the prevention and treatment of diarrhea. However, there is a p...

journal_title：Therapeutics and clinical risk management

authors： Abegaz TM,Belachew SA,Abebe TB,Gebresilassie BM,Teni FS,Woldie HG

更新日期：2016-04-05 00:00:00

abstract：:A "Meeting on Upstream Rotavirus Vaccines and Emerging Vaccine Producers" was held at the World Health Organization in Geneva, Switzerland on March 28-30, 2006. The purpose was to discuss, evaluate, and weigh the importance of additional rotavirus vaccine candidates following the successful international licensure of ...

journal_title：Therapeutics and clinical risk management

authors： Ward RL,McNeal MM,Steele AD

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Available literature suggests that the advantage of animal-derived surfactants over first-generation synthetic agents derives from the presence of surface-active proteins and their phospholipid content. Here we summarize the results of clinical trials comparing animal-derived surfactant preparations with o...

journal_title：Therapeutics and clinical risk management

authors： Logan JW,Moya FR

更新日期：2009-02-01 00:00:00

abstract：:Mucositis pain is a major clinical problem associated with cancer treatment. Mucosal tissue injury is a dose-limiting side effect and also limits nutritional intake and oral function, resulting in weight loss and nutritional deficits for many patients. The pathophysiology of mucositis is thought to be a complex array ...

journal_title：Therapeutics and clinical risk management

authors： Harris DJ

更新日期：2006-09-01 00:00:00

abstract：:Lobomycosis is a subcutaneous mycosis of chronic evolution caused by the Lacazia loboi fungus. Its distribution is almost exclusive in the Americas, and it has a particularly high prevalence in the Amazon basin. Cases of lobomycosis have been reported only in dolphins and humans. Its prevalence is higher among men who...

journal_title：Therapeutics and clinical risk management

authors： Francesconi VA,Klein AP,Santos AP,Ramasawmy R,Francesconi F

更新日期：2014-10-09 00:00:00

abstract：:The development of nonsteroidal anti-inflammatory drugs (NSAIDs) selective for cyclooxygenase (COX)-2 (named coxibs) has been driven by the aim of reducing the incidence of serious gastrointestinal (GI) adverse events associated with the administration of traditional (t) NSAIDs - mainly dependent on the inhibition of ...

journal_title：Therapeutics and clinical risk management

authors： Patrignani P,Tacconelli S,Capone ML

更新日期：2008-10-01 00:00:00

abstract：:In January 2012, glucarpidase (Voraxaze(®)) received approval from the US Food and Drug Administration for intravenous treatment of toxic plasma methotrexate concentrations due to impaired renal clearance. Methotrexate, an antifolate agent, has been used for over 60 years in the treatment of various cancers. High-dose...

journal_title：Therapeutics and clinical risk management

authors： Green JM

更新日期：2012-01-01 00:00:00

abstract：:Eslicarbazepine is a new dibenzazepine antiepileptic agent. It is a high affinity antagonist of the voltage-gated sodium channel. It is closely related to both carbamazepine and oxcarbazepine. Eslicarbazepine has similar affinity to inactivated sodium channels (channels in just activated neurons) as carbamazepine, and...

journal_title：Therapeutics and clinical risk management

authors： Brown ME,El-Mallakh RS

更新日期：2010-04-15 00:00:00

abstract：:The C-MAC videolaryngoscope was evaluated for intubation in patients with predicted extremely difficult airway. The presented cases are patients with neoplasm tumors in larynx. In all cases, awake intubation using C-MAC videolaryngoscope was performed in patients breathing spontaneously, under local anaesthesia, with ...

journal_title：Therapeutics and clinical risk management

authors： Gaszyński T

更新日期：2018-03-14 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a chronic disease that affects 14.2% of the US adult population. Despite being widespread, little is known about the etiology of CRS. Treatment has been symptomatic and focused on relieving symptoms. Recent investigations into causes of CRS have revealed that most CRS patients have an e...

journal_title：Therapeutics and clinical risk management

authors： Kern EB,Sherris D,Stergiou AM,Katz LM,Rosenblatt LC,Ponikau J

更新日期：2007-06-01 00:00:00

abstract：:Cerebral palsy (CP) is the main cause of physical disability in childhood and is an important health issue that has a strong socioeconomic impact. There is no effective treatment for CP and therapeutic approaches report only partial benefits for affected people. In this study we assessed the effects of growth hormone ...

journal_title：Therapeutics and clinical risk management

authors： Devesa J,Alonso B,Casteleiro N,Couto P,Castañón B,Zas E,Reimunde P

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The aims of this study were to explore the correlation between chronic hepatitis B virus (HBV) drug-resistant mutation profiles and the efficacy of nucleoside analog rescue therapy in patients with initial antiviral treatment failure. PATIENTS AND METHODS:Patients with initial antiviral therapy fai...

journal_title：Therapeutics and clinical risk management

authors： Liang LB,Chen LL,Chen EQ,Liao J,Tang H

更新日期：2015-03-12 00:00:00

abstract：:COVID-19 pandemic is inducing acute respiratory distress syndrome, multi-organ failure, and eventual death. Respiratory failure is the leading cause of mortality in the elderly population with pre-existing medical conditions. This group is particularly vulnerable to infections due to a declined immune system, comorbid...

journal_title：Therapeutics and clinical risk management

authors： Rahman S,Singh K,Dhingra S,Charan J,Sharma P,Islam S,Jahan D,Iskandar K,Samad N,Haque M

更新日期：2020-10-20 00:00:00

abstract：Background:Although complications have been associated with head clamp systems, few reports have described head slippage. The present study aimed to determine risk factors for head slippage and speculated that the position of head holder pins might be associated. Patients and Methods:We reviewed medical records and co...

journal_title：Therapeutics and clinical risk management

authors： Sakakura K,Fujimoto A,Ichikawa N,Ishikawa E,Matsumura A,Enoki H,Okanishi T

更新日期：2020-03-25 00:00:00

abstract：:Hyperphosphatemia is an inevitable consequence of end stage chronic kidney disease and is present in the majority of dialysis patients. Recent observational data has associated hyperphosphatemia with increased cardiovascular mortality among dialysis patients. Dietary restriction of phosphate and current dialysis presc...

journal_title：Therapeutics and clinical risk management

authors： Mohammed IA,Hutchison AJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Influenza A H1N1 and H3N2 are two influenza waves that have been identified in past years. METHODS:Data from 77 inpatients from three tertiary hospitals were included and statistical analysis was performed in three different clusters. RESULTS:Thirty-four patients (44.2%) had respiratory distress upon admis...

journal_title：Therapeutics and clinical risk management

authors： Petridis D,Zarogoulidis P,Kallianos A,Kioumis I,Trakada G,Spyratos D,Papaiwannou A,Porpodis K,Huang H,Rapti A,Hohenforst-Schmidt W,Zarogoulidis K

更新日期：2014-02-07 00:00:00

abstract：:Metachromatic leukodystrophy (MLD) disorder is a rare lysosomal storage disorder that leads to severe neurological symptoms and an early death. MLD occurs due to the deficiency of enzyme arylsulfatase A (ARSA) in leukocytes, and patients with MLD excrete sulfatide in their urine. In this study, the ARSA gene in 12 non...

journal_title：Therapeutics and clinical risk management

authors： Dehghan Manshadi M,Kamalidehghan B,Aryani O,Khalili E,Dadgar S,Tondar M,Ahmadipour F,Yong Meng G,Houshmand M

更新日期：2017-06-16 00:00:00

abstract：:The myelodysplastic syndromes (MDS) are a heterogeneous group of disorders that manifest as bone marrow failure with the risk of life threatening infections and bleeding. A third of these patients may transform to acute leukemia. Age and co-morbidities have limited treatment in the majority to supportive care with a m...

journal_title：Therapeutics and clinical risk management

authors： Raj K,Mufti GJ

更新日期：2006-12-01 00:00:00

abstract：:Glucocorticoids are commonly used in various fields within medicine. One of their most common and clinically significant side effects is glucocorticoid-induced osteoporosis (GIOP). GIOP is a disease leading to progressive decreases in bone mineral density, decreased bone strength, and increased risk of skeletal fractu...

journal_title：Therapeutics and clinical risk management

authors： Lau AN,Adachi JD

更新日期：2010-10-21 00:00:00

abstract：Purpose:To determine the early effects of intravitreal anti-VEGF and dexamethasone application on blood flow velocities in patients with retinal vein occlusions. Methods:The ophthalmic (OA) and the central retinal arteries (CRAs) of the affected and unaffected eyes of 21 patients with central retinal vein occlusion (C...

journal_title：Therapeutics and clinical risk management

authors： Ciloglu E,Yıldırım Celikdemir A

更新日期：2019-07-04 00:00:00

abstract：Purpose:To analyze the treatment patterns of psoriatic arthritis (PSA) or ankylosing spondylitis (AS) patients under biological therapies and to evaluate in this population the health-care resource consumption and related costs. Patients and Methods:A retrospective analysis was performed on administrative databases of...

journal_title：Therapeutics and clinical risk management

authors： Perrone V,Giacomini E,Sangiorgi D,Andretta M,Menti AM,Naclerio M,Ritrovato D,Degli Esposti L

更新日期：2020-06-09 00:00:00

abstract：:Treatment of advanced, recurrent or persistent cervical cancer includes radiotherapy and chemotherapy. Radiation has been the primary treatment modality for locoregionally advanced cervical cancer. Concomitant systemic cisplatin chemotherapy and radiation have shown high response rates with improvements in durable rem...

journal_title：Therapeutics and clinical risk management

authors： Robati M,Holtz D,Dunton CJ

更新日期：2008-02-01 00:00:00

abstract：Background:Cardiovascular diseases (CVDs) are the main complication leading to morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). There is a large amount of evidence to support the use of lipid-lowering therapy (LLT) for the prevention of CVD. This study aimed to assess the effectiveness and p...

journal_title：Therapeutics and clinical risk management

authors： Elnaem MH,Mohamed MHN,Huri HZ,Shah ASM

更新日期：2019-01-18 00:00:00

abstract：:Hemodialysis (HD) patients are more susceptible to infective endocarditis (IE) due to the increased risk of bacterial invasion through intravascular access. However, it remains unclear whether the causative organisms and outcomes of IE in HD patients differ from those in non-HD patients. This study clarified the diffe...

journal_title：Therapeutics and clinical risk management

authors： Hsiao CC,Weng CH,Li YJ,Wu HH,Chen YC,Chen YM,Hsu HH,Tian YC

更新日期：2017-05-24 00:00:00

abstract：:Hepatitis C virus (HCV) management in the transplant setting is still an open issue. The therapeutic strategies being addressed include: (a) pre-transplant prophylaxis (to prevent the infection of the transplanted organ); (b) post-transplant prophylaxis (to reduce the possibility of developing acute hepatitis); (c) ma...

journal_title：Therapeutics and clinical risk management

authors： Picciotto A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Iron-deficiency anemia is the most common nutritional cause of anemia in pregnancy and is often responsible for puerperal anemia. Puerperal anemia can impair postpartum maternal and neonatal well-being. OBJECTIVE:To determine the effect of treatment of moderate puerperal iron-deficiency anemia using a singl...

journal_title：Therapeutics and clinical risk management

authors： Iyoke CA,Emegoakor FC,Ezugwu EC,Lawani LO,Ajah LO,Madu JA,Ezegwui HU,Ezugwu FO

更新日期：2017-05-17 00:00:00

abstract：:The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

更新日期：2009-06-01 00:00:00