Abstract:
:Lobomycosis is a subcutaneous mycosis of chronic evolution caused by the Lacazia loboi fungus. Its distribution is almost exclusive in the Americas, and it has a particularly high prevalence in the Amazon basin. Cases of lobomycosis have been reported only in dolphins and humans. Its prevalence is higher among men who are active in the forest, such as rubber tappers, bushmen, miners, and Indian men. It is recognized that the traumatic implantation of the fungus on the skin is the route by which humans acquire this infection. The lesions affect mainly exposed areas such as the auricles and upper and lower limbs and are typically presented as keloid-like lesions. Currently, surgical removal is the therapeutic procedure of choice in initial cases. Despite the existing data and studies to date, the active immune mechanisms in this infection and its involvement in the control or development of lacaziosis have not been fully clarified. In recent years, little progress has been made in the appraisal of the epidemiologic aspects of the disease. So far, we have neither a population-based study nor any evaluation directed to the forest workers.
journal_name
Ther Clin Risk Managjournal_title
Therapeutics and clinical risk managementauthors
Francesconi VA,Klein AP,Santos AP,Ramasawmy R,Francesconi Fdoi
10.2147/TCRM.S46251subject
Has Abstractpub_date
2014-10-09 00:00:00pages
851-60eissn
1176-6336issn
1178-203Xpii
tcrm-10-851journal_volume
10pub_type
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