Amiodarone and risk of liver cirrhosis: a nationwide, population-based study.

abstract：Background:Cardiovascular diseases (CVDs) are the main complication leading to morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). There is a large amount of evidence to support the use of lipid-lowering therapy (LLT) for the prevention of CVD. This study aimed to assess the effectiveness and p...

journal_title：Therapeutics and clinical risk management

authors： Elnaem MH,Mohamed MHN,Huri HZ,Shah ASM

更新日期：2019-01-18 00:00:00

abstract：Purpose:To analyze the treatment patterns of psoriatic arthritis (PSA) or ankylosing spondylitis (AS) patients under biological therapies and to evaluate in this population the health-care resource consumption and related costs. Patients and Methods:A retrospective analysis was performed on administrative databases of...

journal_title：Therapeutics and clinical risk management

authors： Perrone V,Giacomini E,Sangiorgi D,Andretta M,Menti AM,Naclerio M,Ritrovato D,Degli Esposti L

更新日期：2020-06-09 00:00:00

abstract：:Background: Endoscopic sinus surgery (ESS) has been the definitive treatment for chronic rhinosinusitis (CRS), but the complications caused perioperatively may affect patients' quality of life (QoL). This study aims to evaluate the effects of enhanced recovery after surgery (ERAS) on improving perioperative QoL in ESS...

journal_title：Therapeutics and clinical risk management

authors： Wu X,Kong W,Zhu Q,Wang W,Xu H,Zhou S,Yang Q

更新日期：2019-06-04 00:00:00

abstract：OBJECTIVE:To determine the influence of various patient-specific factors, use of concomitant medications, and weekly vitamin K intake on total weekly warfarin maintenance dose (TWD). METHODS:Information collected, via retrospective chart review, included TWD, general demographics, vitamin K consumption, target INR ran...

journal_title：Therapeutics and clinical risk management

authors： Whitley HP,Fermo JD,Chumney EC,Brzezinski WA

更新日期：2007-06-01 00:00:00

abstract：:Paclitaxel is an anticancer agent effective for the treatment of breast, ovarian, lung, and head and neck cancer. Because of water insolubility, paclitaxel is formulated with the micelle-forming vehicle Cremophor EL to enhance drug solubility. However, the addition of Cremophor EL results in hypersensitivity reactions...

journal_title：Therapeutics and clinical risk management

authors： Scripture CD,Figg WD,Sparreboom A

更新日期：2005-06-01 00:00:00

abstract：:A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act) cycle was used for continuous quality improvement. The proportio...

journal_title：Therapeutics and clinical risk management

authors： Zhu LL,Xu LC,Wang HQ,Jin JF,Wang HF,Zhou Q

更新日期：2012-01-01 00:00:00

abstract：Objectives:International experts recently characterized interstitial pneumonia with autoimmune features (IPAF) as a provisional diagnosis for patients with interstitial lung disease who have characteristics of autoimmune disease but do not meet criteria for a specific autoimmune disease. We describe clinical characteri...

journal_title：Therapeutics and clinical risk management

authors： McCoy SS,Mukadam Z,Meyer KC,Kanne JP,Meyer CA,Martin MD,Sampene E,Aesif SW,Rice LN,Bartels CM

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:International travelers from non-endemic areas are at high risk of contracting malaria due to their lack of immunity. Prevention is therefore of outmost importance and is achieved through effective and safe chemoprophylaxis, which reduces the risk of fatal disease. Among the various antimalarial drugs availab...

journal_title：Therapeutics and clinical risk management

authors： Nicosia V,Colombo G,Consentino M,Di Matteo S,Mika F,De Sanctis S,Ratti S,Vinci M

更新日期：2008-10-01 00:00:00

abstract：:Japanese encephalitis (JE) is one of severe viral encephalitis that affects individuals in Asia, western Pacific countries, and northern Australia. Although 67,900 JE cases have been estimated among 24 JE epidemic countries annually, only 10,426 have been reported in 2011. With the establishment of JE surveillance and...

journal_title：Therapeutics and clinical risk management

authors： Wang H,Liang G

更新日期：2015-03-19 00:00:00

abstract：:Treatment of HIV-1 infection has produced dramatic success for many patients. Nevertheless, viral resistance continues to limit the efficacy of currently available agents in many patients. The CCR5 antagonists are a new class of antiretroviral agents that target a necessary coreceptor for viral entry of many strains o...

journal_title：Therapeutics and clinical risk management

authors： Schlecht HP,Schellhorn S,Dezube BJ,Jacobson JM

更新日期：2008-04-01 00:00:00

abstract：:Ongoing neuronal death in Parkinson's disease (PD) causes an altered neurotransmission of various biogenic amines, particularly dopamine. As these changes do not follow a distinct pattern, they vary individually, and are differently pronounced. As a result, a heterogeneous onset of motor and nonmotor features occurs i...

journal_title：Therapeutics and clinical risk management

authors： Müller T

更新日期：2016-08-02 00:00:00

abstract：Purpose:We aimed to build a model to qualitatively and quantitatively evaluate publications of research of spinal cord injury rehabilitation from 1997 to 2016. Methods:Data were obtained from the Web of Science Core Collection on October 6, 2017. We conducted a qualitative and quantitative analysis of publication outp...

journal_title：Therapeutics and clinical risk management

authors： Liu X,Liu N,Zhou M,Lu Y,Li F

更新日期：2018-12-17 00:00:00

abstract：:Metachromatic leukodystrophy (MLD) disorder is a rare lysosomal storage disorder that leads to severe neurological symptoms and an early death. MLD occurs due to the deficiency of enzyme arylsulfatase A (ARSA) in leukocytes, and patients with MLD excrete sulfatide in their urine. In this study, the ARSA gene in 12 non...

journal_title：Therapeutics and clinical risk management

authors： Dehghan Manshadi M,Kamalidehghan B,Aryani O,Khalili E,Dadgar S,Tondar M,Ahmadipour F,Yong Meng G,Houshmand M

更新日期：2017-06-16 00:00:00

abstract：AIM:The aim of this study was to evaluate the efficacy of, and patients' subjective responses to, periodontal ligament (PDL) anesthetic injection compared to traditional local-anesthetic infiltration injection for the nonsurgical extraction of one posterior maxillary permanent tooth. MATERIALS AND METHODS:All patients...

journal_title：Therapeutics and clinical risk management

authors： Al-Shayyab MH

更新日期：2017-10-06 00:00:00

abstract：:Adoptive T-cell immunotherapy is a rapidly growing field and is shifting the paradigm of clinical cancer treatment. Axicabtagene ciloleucel (axi-cel) is an anti-CD19 chimeric antigen receptor T-cell therapy that was initially developed at the National Cancer Institute and has recently been commercially approved by the...

journal_title：Therapeutics and clinical risk management

authors： Jain MD,Bachmeier CA,Phuoc VH,Chavez JC

更新日期：2018-05-31 00:00:00

abstract：Introduction:Severe hand, foot, and mouth disease (HFMD) may lead to serious complications, which cause child mortality during outbreaks. The aim of this study was to determine whether neutrophil-to-lymphocyte ratio (NLR) can predict death risk in severe HFMD. Methods:Medical records for 664 severe HFMD patients were ...

journal_title：Therapeutics and clinical risk management

authors： Li Y,Wang M,Wang W,Feng D,Deng H,Zhang Y,Dang S,Zhai S

更新日期：2020-10-23 00:00:00

abstract：Background:Our aim was to investigate the postoperative analgesic effect of ultrasound (US)-guided bilateral transversus abdominis plane (TAP) blocks combined with rectus sheath blocks (RSBs) in laparoscopic hepatectomy. Patients and Methods:A total of 126 patients were allocated into two groups for analysis. Group 1 ...

journal_title：Therapeutics and clinical risk management

authors： Lu X,Yu P,Ou C,Wang J,Zhou Z,Lai R

更新日期：2020-09-18 00:00:00

abstract：:Some specific features of the 24 h blood pressure (BP) pattern are linked to the progressive injury of target tissues and the triggering of cardiac and cerebrovascular events. In particular, many studies show the extent of the nocturnal BP decline relative to the diurnal BP mean (the diurnal/nocturnal ratio, an index ...

journal_title：Therapeutics and clinical risk management

authors： Hermida RC,Ayala DE,Calvo C

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Acute heart failure (AHF) is a serious condition that is associated with increased mortality in critically ill patients. Previous studies indicated that environmental exposure to cadmium increases mortality of general populations. However, the relationship of cadmium exposure and mortality is unclear for AHF...

journal_title：Therapeutics and clinical risk management

authors： Hsu CW,Weng CH,Lee CC,Lin-Tan DT,Chu PH,Chen KH,Yen TH,Huang WH

更新日期：2017-03-27 00:00:00

abstract：Purpose:To determine the early effects of intravitreal anti-VEGF and dexamethasone application on blood flow velocities in patients with retinal vein occlusions. Methods:The ophthalmic (OA) and the central retinal arteries (CRAs) of the affected and unaffected eyes of 21 patients with central retinal vein occlusion (C...

journal_title：Therapeutics and clinical risk management

authors： Ciloglu E,Yıldırım Celikdemir A

更新日期：2019-07-04 00:00:00

abstract：Background:There are many surgical procedures that can be used to relieve compression caused by thoracic ossification of the ligamentum flavum (TOLF). The present study aims to retrospectively observe the differences in subsection laminectomy with pedicle screw fixation (SLPF) and lamina osteotomy and replantation with...

journal_title：Therapeutics and clinical risk management

authors： Zhang JT,Lei T,Yang L,Lin YS,Wang ZH,Cao JM

更新日期：2020-04-17 00:00:00

abstract：:The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

更新日期：2009-06-01 00:00:00

abstract：:Erectile dysfunction (ED) is often perceived by both patients and sexual partners as a serious problem that can jeopardize quality of life, psychosocial or emotional well-being, and the partnership in the long term. Since their introduction, oral phosphodiesterase type 5 inhibitors (PDE5Is) have been found to be highl...

journal_title：Therapeutics and clinical risk management

authors： Cho MC,Paick JS

更新日期：2014-05-14 00:00:00

abstract：:Coronary and cerebrovascular atherothrombosis are the leading cause of mortality and morbidity worldwide. Novel antiplatelet agents have been established for the management of patients with clinically evident coronary atherothrombosis and are increasingly used in these patients. These agents, however, have shown limit...

journal_title：Therapeutics and clinical risk management

authors： Iannopollo G,Camporotondo R,De Ferrari GM,Leonardi S

更新日期：2014-05-02 00:00:00

abstract：BACKGROUND:Adverse drug reactions are important determinants of inpatient and outpatient morbidity. Thiocolchicoside is a semisynthetic derivate of naturally occurring colchicoside, which is largely used in humans as a centrally acting muscle relaxant. Epileptic seizures after thiocolchicoside intake have been reported...

journal_title：Therapeutics and clinical risk management

authors： Giavina-Bianchi P,Giavina-Bianchi M,Tanno LK,Ensina LF,Motta AA,Kalil J

更新日期：2009-06-01 00:00:00

abstract：:Heart failure (HF) is a major public health priority due to its epidemiological transition and the world's aging population. HF is typified by continuous loss of contractile function with reduced, normal, or preserved ejection fraction, elevated vascular resistance, fluid and autonomic imbalance, and ventricular dilat...

journal_title：Therapeutics and clinical risk management

authors： Bonsu KO,Owusu IK,Buabeng KO,Reidpath DD,Kadirvelu A

更新日期：2016-06-03 00:00:00

abstract：Background:Wells and Geneva scores are widely used in the assessment of pretest probability of pulmonary embolism (PE). Objective:The objective of this study was to examine the hypothesis that mean platelet volume (MPV) may better predict PE than the clinical prediction rules. Methods:A study was performed among pati...

journal_title：Therapeutics and clinical risk management

authors： Lipinska A,Ledakowicz-Polak A,Krauza G,Przybylak K,Zielinska M

更新日期：2018-11-09 00:00:00

abstract：INTRODUCTION:Available literature suggests that the advantage of animal-derived surfactants over first-generation synthetic agents derives from the presence of surface-active proteins and their phospholipid content. Here we summarize the results of clinical trials comparing animal-derived surfactant preparations with o...

journal_title：Therapeutics and clinical risk management

authors： Logan JW,Moya FR

更新日期：2009-02-01 00:00:00

abstract：Objective:Retrospective studies and a meta-analysis were performed to evaluate the safety and effectiveness of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP) during cardiac surgery under extracorporeal circulation. Methods:Computerized literature searches were performed in Medl...

journal_title：Therapeutics and clinical risk management

authors： Hua P,Liu J,Tao J,Lin X,Zou R,Zhang D,Yang S

更新日期：2018-02-20 00:00:00

abstract：AIM:To compare the long-term survival outcomes of radiofrequency ablation and liver resection for single very early/early stage hepatocellular carcinoma (HCC). METHODS:The Cochrane Library (Issue 3, 2015), Embase (1974 to March 15, 2015), PubMed (1950 to March 15, 2015), Web of Science (1900 to March 15, 2015), and Ch...

journal_title：Therapeutics and clinical risk management

authors： He ZX,Xiang P,Gong JP,Cheng NS,Zhang W

更新日期：2016-02-23 00:00:00