Bacteremia and endocarditis due to methicillin-resistant Staphylococcus aureus: the potential role of daptomycin.

Abstract:

:Staphylococcus aureus bacteremia is a common disease with a high risk of mortality and complications. An increasing proportion of cases are methicillin-resistant S.aureus (MRSA), and methicillin-resistance is being observed from both community-acquired bacteremias and in healthcare-associated infections. The duration of bacteremia and transesophageal echocardiographic findings are useful in predicting the likelihood of complications including endocarditis. Therapy with vancomycin has been the mainstay in the treatment of MRSA bacteremias, but is associated with a long duration of bacteremia on therapy and relapses. Loss of susceptibility to vancomycin, due to thickened cell walls and through the acquisition of the vanA gene, has been described. Daptomycin is newly approved lipopeptide that is highly bactericidal against most strains of MRSA. In a randomized trial, daptomycin was demonstrated to be effective in the treatment of S. aureus bacteremia and right-sided endocarditis. However treatment failures associated with isolates with daptomycin non-susceptibility are reported, and there is a correlation between isolates with reduced vancomycin susceptibility and reduced daptomycin susceptibility. Daptomycin is a useful alternative to vancomycin in the therapy of MRSA bacteremia and endocarditis. However the appropriate role of daptomycin in optimizing therapy with MRSA bacteremia and endocarditis remains to be elucidated.

journal_name

Ther Clin Risk Manag

authors

Bamberger DM

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

675-84

issue

4

eissn

1176-6336

issn

1178-203X

journal_volume

3

pub_type

杂志文章
  • The lupus band test in systemic lupus erythematosus patients.

    abstract::The lupus band test (LBT) is a diagnostic procedure that is used to detect deposits of immunoglobulins and complement components along the dermoepidermal junction in patients with lupus erythematosus (LE). The LBT is positive in about 70%-80% of sun-exposed non-lesional skin specimens obtained from patients with syste...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S10145

    authors: Reich A,Marcinow K,Bialynicki-Birula R

    更新日期:2011-01-24 00:00:00

  • Comparative study on drug safety surveillance between medical students of Malaysia and Nigeria.

    abstract:BACKGROUND:Internationally, there is a remarkable achievement in the areas of drug discovery, drug design, and clinical trials. New and efficient drug formulation techniques are widely available which have led to success in treatment of several diseases. Despite these achievements, large number of patients continue to ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S85019

    authors: Abubakar AR,Ismail S,Rahman NI,Haque M

    更新日期:2015-06-30 00:00:00

  • The use of amisulpride in the treatment of acute psychosis.

    abstract::The management of acute episodes in schizophrenia is frequently initiated in the psychiatric emergency department and requires rapid intervention to relieve distress and psychiatric symptoms. Both non-pharmacological and pharmacological interventions are needed to calm the patient and prevent potential harm to the pat...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2007.3.1.3

    authors: Nuss P,Hummer M,Tessier C

    更新日期:2007-03-01 00:00:00

  • Resistance and the management of complicated skin and skin structure infections: the role of ceftobiprole.

    abstract::Antimicrobial resistant bacteria are an increasing concern due to the resulting increase in morbidity, mortality, and health-care costs associated with the administration of inadequate or delayed antimicrobial therapy. The implications of inadequate antimicrobial therapy in complicated skin and skin structure infectio...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S5823

    authors: Barbour A,Derendorf H

    更新日期:2010-10-05 00:00:00

  • Neutrophil-lymphocyte ratio as an early new marker in AIV-H7N9-infected patients: a retrospective study.

    abstract::Background: Avian AIV-H7N9 influenza progresses rapidly and has a high fatality rate. However, it lacks an early effective biomarker to predict disease severity and fatal outcomes successfully. Our study aimed to explore whether the neutrophil-to-lymphocyte ratio (NLR) taken within 24 h after admission can predict dis...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S206930

    authors: Zhang Y,Zou P,Gao H,Yang M,Yi P,Gan J,Shen Y,Wang W,Zhang W,Li J,Liu P,Li L

    更新日期:2019-07-24 00:00:00

  • Effects of treatment with antimicrobial agents on the human colonic microflora.

    abstract::Antimicrobial agents are the most valuable means available for treating bacterial infections. However, the administration of therapeutic doses of antimicrobial agents to patients is a leading cause of disturbance of the normal gastrointestinal microflora. This disturbance results in diminishing the natural defense mec...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s4328

    authors: Rafii F,Sutherland JB,Cerniglia CE

    更新日期:2008-12-01 00:00:00

  • Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time.

    abstract::Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduc...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s2838

    authors: Ly T,Gulia J,Pyrgos V,Waga M,Shoham S

    更新日期:2008-06-01 00:00:00

  • Successful treatment for acute prosthetic joint infection due to MRSA and Candida albicans: a case report and literature review.

    abstract::Methicillin-resistant Staphylococcus aureus (MRSA) and Candidal prosthetic joint infections (PJIs) are very rare, and the optimal management for these patients is still unknown. A 54-year-old man with traumatic arthritis due to previous electric injury successfully retained the implant despite the successive infection...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S165247

    authors: Xiang Y,Xuan YY,Li G

    更新日期:2018-06-20 00:00:00

  • Cost-effectiveness analysis of HIV treatment in the clinical practice of a public hospital in northern Italy.

    abstract:INTRODUCTION:We carried out an economic analysis to assess the cost-effectiveness of highly active antiretroviral therapy (HAART) regimens in Italy for the management of human immunodeficiency virus (HIV)-infected patients according to clinical practice in the Infectious Diseases Department of "L. Sacco" Hospital, Mila...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S33674

    authors: Rizzardini G,Bonfanti P,Carenzi L,Coen M,Orlando G,Di Matteo S,Colombo GL

    更新日期:2012-01-01 00:00:00

  • Association of diabetes-related distress, depression, medication adherence, and health-related quality of life with glycated hemoglobin, blood pressure, and lipids in adult patients with type 2 diabetes: a cross-sectional study.

    abstract::This study examined the associations of diabetes-related distress (DRD), depressive symptoms, health-related quality of life (HRQoL), and medication adherence with glycemia, blood pressure (BP), and lipid biomarkers in adults with type 2 diabetes mellitus (T2D). This cross-sectional study was conducted in three Malays...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S81623

    authors: Chew BH,Sherina MS,Hassan NH

    更新日期:2015-04-29 00:00:00

  • Diagnosis and treatment of chronic rhinosinusitis: focus on intranasal Amphotericin B.

    abstract::Chronic rhinosinusitis (CRS) is a chronic disease that affects 14.2% of the US adult population. Despite being widespread, little is known about the etiology of CRS. Treatment has been symptomatic and focused on relieving symptoms. Recent investigations into causes of CRS have revealed that most CRS patients have an e...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2007.3.2.319

    authors: Kern EB,Sherris D,Stergiou AM,Katz LM,Rosenblatt LC,Ponikau J

    更新日期:2007-06-01 00:00:00

  • Review of novel therapeutic targets for improving heart failure treatment based on experimental and clinical studies.

    abstract::Heart failure (HF) is a major public health priority due to its epidemiological transition and the world's aging population. HF is typified by continuous loss of contractile function with reduced, normal, or preserved ejection fraction, elevated vascular resistance, fluid and autonomic imbalance, and ventricular dilat...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S106065

    authors: Bonsu KO,Owusu IK,Buabeng KO,Reidpath DD,Kadirvelu A

    更新日期:2016-06-03 00:00:00

  • Inferior vena cava filters in cancer patients: to filter or not to filter.

    abstract:PURPOSE:Cancer and its treatment are recognized risk factors for venous thromboembolism (VTE); active cancer accounts for almost 20% of all newly diagnosed VTE. Inferior vena cava (IVC) filters are utilized to provide mechanical thromboprophylaxis to prevent pulmonary embolism (PE) or to avoid bleeding from systemic an...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S17912

    authors: Abdel-Razeq H,Mansour A,Ismael Y,Abdulelah H

    更新日期:2011-01-01 00:00:00

  • A comparison of McGrath MAC, Pentax AWS, and Macintosh direct laryngoscopes for nasotracheal intubation: a randomized controlled trial.

    abstract:Purpose:Videolaryngoscopy in nasotracheal intubation has been reported to be better than direct laryngoscopy. The most suitable type of videolaryngoscope remains unknown. This study aimed to compare two videolaryngoscopes (McGrath MAC and Pentax AWS) with a Macintosh laryngoscope during nasotracheal intubation. Method...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S220451

    authors: Chae YJ,Kim DH,Park EJ,Oh J,Yi IK

    更新日期:2019-09-18 00:00:00

  • Erratum: A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial [Corrigendum].

    abstract::[This corrects the article on p. 741 in vol. 14, PMID: 29719401.]. ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 已发布勘误

    doi:10.2147/TCRM.S177217

    authors:

    更新日期:2018-06-26 00:00:00

  • Management of children's acute diarrhea by community pharmacies in five towns of Ethiopia: simulated client case study.

    abstract:BACKGROUND:Acute diarrhea is the major cause of child morbidity and mortality in low-income nations. It is the second most common cause of death among children <5 years of age globally. The indispensable role of community pharmacists is clearly observed in the prevention and treatment of diarrhea. However, there is a p...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S98474

    authors: Abegaz TM,Belachew SA,Abebe TB,Gebresilassie BM,Teni FS,Woldie HG

    更新日期:2016-04-05 00:00:00

  • Serum glutathione transferase does not respond to indole-3-carbinol: A pilot study.

    abstract:BACKGROUND:Despite the well recognized protective effect of cruciferous vegetables against various cancers, including human colorectal cancers, little is known about how this effect is conferred. It is thought that some phytochemicals found only in these vegetables confer the protection. These compounds include the glu...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s9568

    authors: McGrath DR,Frydoonfar H,Hunt JJ,Dunkley CJ,Spigelman AD

    更新日期:2010-05-25 00:00:00

  • Randomized Phase III evaluation of the efficacy and safety of a novel glycopyrrolate oral solution for the management of chronic severe drooling in children with cerebral palsy or other neurologic conditions.

    abstract:AIM:To evaluate the efficacy of glycopyrrolate oral solution (1 mg/5 mL) in managing problem drooling associated with cerebral palsy and other neurologic conditions. METHOD:Thirty-eight patients aged 3-23 years weighing at least 27 lb (12.2 kg) with severe drooling (clothing damp 5-7 days/week) were randomized to glyc...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S26893

    authors: Zeller RS,Lee HM,Cavanaugh PF,Davidson J

    更新日期:2012-01-01 00:00:00

  • Cancer treatment-induced mucositis pain: strategies for assessment and management.

    abstract::Mucositis pain is a major clinical problem associated with cancer treatment. Mucosal tissue injury is a dose-limiting side effect and also limits nutritional intake and oral function, resulting in weight loss and nutritional deficits for many patients. The pathophysiology of mucositis is thought to be a complex array ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2006.2.3.251

    authors: Harris DJ

    更新日期:2006-09-01 00:00:00

  • Risk of breast cancer recurrence in patients receiving manual lymphatic drainage: a hospital-based cohort study.

    abstract:BACKGROUND:This retrospective cohort study evaluated whether manual lymphatic drainage (MLD) therapy increases the risk of recurrence of breast cancer. METHODS:We analyzed 1,106 women who were diagnosed with stage 0-3 breast cancer between 2007 and 2011 and experienced remission after surgery and adjuvant therapy. The...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S79118

    authors: Hsiao PC,Liu JT,Lin CL,Chou W,Lu SR

    更新日期:2015-02-27 00:00:00

  • The Postoperative Analgesic Effect of Ultrasound-Guided Bilateral Transversus Abdominis Plane Combined with Rectus Sheath Blocks in Laparoscopic Hepatectomy: A Randomized Controlled Study.

    abstract:Background:Our aim was to investigate the postoperative analgesic effect of ultrasound (US)-guided bilateral transversus abdominis plane (TAP) blocks combined with rectus sheath blocks (RSBs) in laparoscopic hepatectomy. Patients and Methods:A total of 126 patients were allocated into two groups for analysis. Group 1 ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S267735

    authors: Lu X,Yu P,Ou C,Wang J,Zhou Z,Lai R

    更新日期:2020-09-18 00:00:00

  • Efficacy versus safety: the dilemma of using novel platelet inhibitors for the treatment of patients with ischemic stroke and coronary artery disease.

    abstract::Coronary and cerebrovascular atherothrombosis are the leading cause of mortality and morbidity worldwide. Novel antiplatelet agents have been established for the management of patients with clinically evident coronary atherothrombosis and are increasingly used in these patients. These agents, however, have shown limit...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S39216

    authors: Iannopollo G,Camporotondo R,De Ferrari GM,Leonardi S

    更新日期:2014-05-02 00:00:00

  • Clinical potential of vorapaxar in cardiovascular risk reduction in patients with atherosclerosis.

    abstract::Vorapaxar (ZONTIVITY™, formerly known as SCH 530348) is a specific, orally active antagonist of the protease-activated receptor-1 (PAR-1) on platelets. It inhibits thrombin-induced platelet activation by binding to the ectodomain of PAR-1. After animal studies and Phase II studies showed that vorapaxar sufficiently in...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S55469

    authors: Diehl P,Bode C,Duerschmied D

    更新日期:2015-08-03 00:00:00

  • Decompressive craniectomy for severe traumatic brain injury patients with fixed dilated pupils.

    abstract:OBJECTIVE:The outcome of decompressive craniectomy (DC) for severe traumatic brain injury (sTBI) patients with fixed dilated pupils (FDPs) is not clear. The objective of this study was to validate the outcome of DC in sTBI patients with FDPs. PATIENTS:We retrospectively collected data from 207 sTBI patients with FDPs ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S89820

    authors: Mao X,Miao G,Hao S,Tao X,Hou Z,Li H,Tian R,Zhang H,Lu T,Ma J,Zhang X,Cheng H,Liu B

    更新日期:2015-10-22 00:00:00

  • Critical appraisal and clinical utility of atosiban in the management of preterm labor.

    abstract::Preterm birth is the major cause of perinatal morbidity and mortality in the developed world, and spontaneous preterm labor is the commonest cause of preterm birth. Interventions to treat women in spontaneous preterm labor have not reduced the incidence of preterm births but this may be due to increased risk factors, ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s9378

    authors: Sanu O,Lamont RF

    更新日期:2010-04-26 00:00:00

  • Calcification score versus arterial stenosis grading: comparison of two CT-based methods for risk assessment of anastomotic leakage after esophagectomy and gastric pull-up.

    abstract:Purpose:Anastomotic leakage is a major surgical complication following esophagectomy and gastric pull-up. Specific risk factors such as celiac trunk (TC) stenosis and high calcification score of the aorta have been identified, but no data are available on their relative prognostic values. This retrospective study aimed...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S157352

    authors: Chang DH,Brinkmann S,Smith L,Becker I,Schroeder W,Hoelscher AH,Haneder S,Maintz D,Spiro JE

    更新日期:2018-04-17 00:00:00

  • Tamsulosin oral controlled absorption system (OCAS) in the treatment of benign prostatic hypertrophy.

    abstract::The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the alpha(1a) and alpha(1d) adrenergic receptor subtypes. The oral-controlled absorption system (OCAS((R))) represents a drug delivery refinement that incorporates a matrix of gel-f...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s86

    authors: Neill MG,Shahani R,Zlotta AR

    更新日期:2008-02-01 00:00:00

  • Retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys.

    abstract::Background: To report our experience with retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys. Methods: We retrospectively reviewed the medical records of 7 patients who underwent retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy at our inst...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S202454

    authors: Qin J,Wang P,Jing T,Kong D,Ye S,Xia D,Wang S

    更新日期:2019-06-11 00:00:00

  • Review of the combined contraceptive vaginal ring, NuvaRing.

    abstract::The purpose of this review was to test contraceptive efficacy, cycle control, tolerability, and acceptability as found in the non-comparative studies with NuvaRing((R)) by those found in the randomized trials comparing NuvaRing and combined oral contraceptives (COCs). All large non-comparative studies and all relevant...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s1964

    authors: Roumen FJ

    更新日期:2008-04-01 00:00:00

  • Early Continence and Extravasation After Open Retropubic Radical Prostatectomy - Interrupted vs Continuous Suturing for Vesicourethral Anastomosis.

    abstract:Purpose:To compare running suture (RS) and interrupted suture (IS) of vesicourethral anastomosis (VUA) during open retropubic radical prostatectomy (RRP) on early urinary continence and extravasation. Patients and Methods:Single center analysis of 211 patients who underwent RRP performed by a single surgeon during 200...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S278454

    authors: Köhler N,El-Bandar N,Maxeiner A,Ralla B,Miller K,Busch J,Friedersdorff F

    更新日期:2020-12-23 00:00:00