Successful treatment for acute prosthetic joint infection due to MRSA and Candida albicans: a case report and literature review.

Abstract:

:Methicillin-resistant Staphylococcus aureus (MRSA) and Candidal prosthetic joint infections (PJIs) are very rare, and the optimal management for these patients is still unknown. A 54-year-old man with traumatic arthritis due to previous electric injury successfully retained the implant despite the successive infection with MRSA and Candida albicans after total knee arthroplasty (TKA). Continuous lavage with vancomycin was used to control MRSA infection and repeated local washout plus oral swallow with voriconazole tablet were administered to eradicate C. albicans. Additional three reported cases were identified by the criteria of selecting patients with concomitant and/or successive MRSA and Candidal PJIs. Different methods were applied with variable outcomes. Therefore, several risk factors such as intra-articular corticosteroid injection, high frequency of door openings in the operating room, excessive blood loss and allogeneic red blood cell transfusions should be avoided. Debridement, antibiotics and implant retention (DAIR) can be an alternative in dedicated patients to control acute MRSA and Candidal PJIs. Particularly, repeated intra-articular washout with susceptible drugs and a prolonged duration of oral antibiotics was essential for microbial control.

journal_name

Ther Clin Risk Manag

authors

Xiang Y,Xuan YY,Li G

doi

10.2147/TCRM.S165247

subject

Has Abstract

pub_date

2018-06-20 00:00:00

pages

1133-1139

eissn

1176-6336

issn

1178-203X

pii

tcrm-14-1133

journal_volume

14

pub_type

杂志文章
  • The use of the C-MAC videolaryngoscope for awake intubation in patients with a predicted extremely difficult airway: case series.

    abstract::The C-MAC videolaryngoscope was evaluated for intubation in patients with predicted extremely difficult airway. The presented cases are patients with neoplasm tumors in larynx. In all cases, awake intubation using C-MAC videolaryngoscope was performed in patients breathing spontaneously, under local anaesthesia, with ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S150536

    authors: Gaszyński T

    更新日期:2018-03-14 00:00:00

  • Treatment with Saccharomyces boulardii and Escherichia coli Nissle is safe and associated with reduced nosocomial transmission of vanB vancomycin-resistant Enterococcus faecium on an early rehabilitation ward in Germany: a retrospective analysis.

    abstract:Purpose:According to the WHO vancomycin-resistant Enterococcus faecium (VRE) belongs to the microorganisms for which new antibiotics are urgently needed. Depending on the type of vancomycin resistance vanA gene VRE is differentiated from vanB VRE and other types. In this retrospective analysis the results of VRE survei...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S179208

    authors: Borgmann S,Rieß B,Siegmund R,Werner G,Klare I

    更新日期:2019-02-27 00:00:00

  • Periodontal ligament injection versus routine local infiltration for nonsurgical single posterior maxillary permanent tooth extraction: comparative double-blinded randomized clinical study.

    abstract:AIM:The aim of this study was to evaluate the efficacy of, and patients' subjective responses to, periodontal ligament (PDL) anesthetic injection compared to traditional local-anesthetic infiltration injection for the nonsurgical extraction of one posterior maxillary permanent tooth. MATERIALS AND METHODS:All patients...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S143173

    authors: Al-Shayyab MH

    更新日期:2017-10-06 00:00:00

  • Use of idarucizumab in reversing dabigatran anticoagulant effect: a critical appraisal.

    abstract::Use of non-vitamin K antagonist oral anticoagulants is spreading in the real world. Despite that, a strong need for antidotes/reversal agents is still reported by several physicians. Idarucizumab is a humanized monoclonal antibody fragment that binds specifically to dabigatran. Idarucizumab was approved in 2015 by the...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S140377

    authors: Proietti M,Boriani G

    更新日期:2018-08-22 00:00:00

  • Review of novel therapeutic targets for improving heart failure treatment based on experimental and clinical studies.

    abstract::Heart failure (HF) is a major public health priority due to its epidemiological transition and the world's aging population. HF is typified by continuous loss of contractile function with reduced, normal, or preserved ejection fraction, elevated vascular resistance, fluid and autonomic imbalance, and ventricular dilat...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S106065

    authors: Bonsu KO,Owusu IK,Buabeng KO,Reidpath DD,Kadirvelu A

    更新日期:2016-06-03 00:00:00

  • Randomized Phase III evaluation of the efficacy and safety of a novel glycopyrrolate oral solution for the management of chronic severe drooling in children with cerebral palsy or other neurologic conditions.

    abstract:AIM:To evaluate the efficacy of glycopyrrolate oral solution (1 mg/5 mL) in managing problem drooling associated with cerebral palsy and other neurologic conditions. METHOD:Thirty-eight patients aged 3-23 years weighing at least 27 lb (12.2 kg) with severe drooling (clothing damp 5-7 days/week) were randomized to glyc...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S26893

    authors: Zeller RS,Lee HM,Cavanaugh PF,Davidson J

    更新日期:2012-01-01 00:00:00

  • Effect of continuous positive airway pressure on allergic rhinitis in patients with obstructive sleep apnea-hypopnea syndrome.

    abstract:Background:The effect of continuous positive airway pressure (CPAP) on nasal symptoms in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) remains controversial. In addition, possible mechanism(s) remains unclear. Objective:To examine whether CPAP contributes to the onset and exacerbation of allergic rhi...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S170548

    authors: Yang Q,Li H,Wu W,Huang X,Tu B,Ma Y,Deng H,Li M,He H,Li C,Yang Y

    更新日期:2018-08-24 00:00:00

  • Role of teriparatide in treatment of glucocorticoid-induced osteoporosis.

    abstract::Glucocorticoids are commonly used in various fields within medicine. One of their most common and clinically significant side effects is glucocorticoid-induced osteoporosis (GIOP). GIOP is a disease leading to progressive decreases in bone mineral density, decreased bone strength, and increased risk of skeletal fractu...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S7776

    authors: Lau AN,Adachi JD

    更新日期:2010-10-21 00:00:00

  • Reducing drug-herb interaction risk with a computerized reminder system.

    abstract:BACKGROUND:Traditional Chinese medicine (TCM) and Western medicine are both popular in Taiwan. Approximately 14.1% of Taiwanese residents use Western drugs and Chinese herbs concurrently; therefore, drug-herb interaction is critical to patient safety. This paper presents a new procedure for reducing the risk of drug in...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S78124

    authors: Lin SS,Tsai CL,Tu CY,Hsieh CL

    更新日期:2015-02-16 00:00:00

  • Anthracycline extravasation injuries: management with dexrazoxane.

    abstract::The application of anthracyclines in anticancer therapy may result in accidental extravasation injury and can be a serious complication of their use. Tissue necrosis with skin ulceration is a possible outcome in the inadvertent extravasation of anthracyclines during intravenous administration. Until recently, there ha...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s3694

    authors: Jordan K,Behlendorf T,Mueller F,Schmoll HJ

    更新日期:2009-04-01 00:00:00

  • Radiofrequency ablation versus resection for Barcelona clinic liver cancer very early/early stage hepatocellular carcinoma: a systematic review.

    abstract:AIM:To compare the long-term survival outcomes of radiofrequency ablation and liver resection for single very early/early stage hepatocellular carcinoma (HCC). METHODS:The Cochrane Library (Issue 3, 2015), Embase (1974 to March 15, 2015), PubMed (1950 to March 15, 2015), Web of Science (1900 to March 15, 2015), and Ch...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S96760

    authors: He ZX,Xiang P,Gong JP,Cheng NS,Zhang W

    更新日期:2016-02-23 00:00:00

  • Association of diabetes-related distress, depression, medication adherence, and health-related quality of life with glycated hemoglobin, blood pressure, and lipids in adult patients with type 2 diabetes: a cross-sectional study.

    abstract::This study examined the associations of diabetes-related distress (DRD), depressive symptoms, health-related quality of life (HRQoL), and medication adherence with glycemia, blood pressure (BP), and lipid biomarkers in adults with type 2 diabetes mellitus (T2D). This cross-sectional study was conducted in three Malays...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S81623

    authors: Chew BH,Sherina MS,Hassan NH

    更新日期:2015-04-29 00:00:00

  • Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

    abstract::The myelodysplastic syndromes (MDS) are a heterogeneous group of disorders that manifest as bone marrow failure with the risk of life threatening infections and bleeding. A third of these patients may transform to acute leukemia. Age and co-morbidities have limited treatment in the majority to supportive care with a m...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2006.2.4.377

    authors: Raj K,Mufti GJ

    更新日期:2006-12-01 00:00:00

  • The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis.

    abstract:BACKGROUND:Metabolic syndrome is a worldwide disorder and also the major risk factor of several systemic diseases. Evidence identifying the association between metabolic syndrome and nephrolithiasis is lacking, especially in Taiwan. AIM:The aim of this study was to investigate the association between nephrolithiasis a...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S125480

    authors: Liu YT,Yang PY,Yang YW,Sun HY,Lin IC

    更新日期:2017-01-06 00:00:00

  • Erratum: A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial [Corrigendum].

    abstract::[This corrects the article on p. 741 in vol. 14, PMID: 29719401.]. ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 已发布勘误

    doi:10.2147/TCRM.S177217

    authors:

    更新日期:2018-06-26 00:00:00

  • Which drugs cause treatment-related problems? Analysis of 10,672 problems within the outpatient setting.

    abstract:Background:Treatment-related problems (TRPs) may pose risks for patients if unaddressed. With the increased complexity of health care, it is important to target pharmacists' efforts to patients that are at high risk for TRPs. Objectives:The present study aimed to identify medications most commonly associated with TRPs...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S180747

    authors: Al-Taani GM,Al-Azzam SI,Alzoubi KH,Aldeyab MA

    更新日期:2018-11-16 00:00:00

  • New orally active anticoagulant agents for the prevention and treatment of venous thromboembolism in cancer patients.

    abstract::Patients with cancer have a 6-7-fold higher risk of venous thromboembolism (VTE) as compared with non-cancer patients. Effective and safe anticoagulation for the prevention and treatment of VTE is the cornerstone of the management of patients with cancer, aiming to decrease morbidity and mortality and to improve quali...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S49063

    authors: Gerotziafas GT,Mahé I,Elalamy I

    更新日期:2014-06-13 00:00:00

  • Udenafil for the treatment of erectile dysfunction.

    abstract::Erectile dysfunction (ED) is often perceived by both patients and sexual partners as a serious problem that can jeopardize quality of life, psychosocial or emotional well-being, and the partnership in the long term. Since their introduction, oral phosphodiesterase type 5 inhibitors (PDE5Is) have been found to be highl...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S39727

    authors: Cho MC,Paick JS

    更新日期:2014-05-14 00:00:00

  • Clinical utility of ingenol mebutate in the management of actinic keratosis: perspectives from clinical practice.

    abstract::Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage. AKs have historically been characterized as being "precancerous"; however, now it is considered by many author...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S145779

    authors: Skroza N,Bernardini N,Proietti I,Potenza C

    更新日期:2018-10-04 00:00:00

  • Photodynamic diagnosis for follow-up of carcinoma in situ of the bladder.

    abstract:INTRODUCTION:A prospective study to evaluate the reliability of cystoscopy was performed with fluorescence (photodynamic diagnosis, PDD) compared with standard white light (WL) cystoscopy in patients with solitary carcinoma in situ (CIS), undergoing BCG treatment. MATERIALS AND METHODS:Between February 2004 and March ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:

    authors: Colombo R,Naspro R,Bellinzoni P,Fabbri F,Guazzoni G,Scattoni V,Losa A,Rigatti P

    更新日期:2007-12-01 00:00:00

  • Effect of treatment with single total-dose intravenous iron versus daily oral iron(III)-hydroxide polymaltose on moderate puerperal iron-deficiency anemia.

    abstract:BACKGROUND:Iron-deficiency anemia is the most common nutritional cause of anemia in pregnancy and is often responsible for puerperal anemia. Puerperal anemia can impair postpartum maternal and neonatal well-being. OBJECTIVE:To determine the effect of treatment of moderate puerperal iron-deficiency anemia using a singl...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S112227

    authors: Iyoke CA,Emegoakor FC,Ezugwu EC,Lawani LO,Ajah LO,Madu JA,Ezegwui HU,Ezugwu FO

    更新日期:2017-05-17 00:00:00

  • Safety and efficacy of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP): a systematic review and meta-analysis.

    abstract:Objective:Retrospective studies and a meta-analysis were performed to evaluate the safety and effectiveness of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP) during cardiac surgery under extracorporeal circulation. Methods:Computerized literature searches were performed in Medl...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S143247

    authors: Hua P,Liu J,Tao J,Lin X,Zou R,Zhang D,Yang S

    更新日期:2018-02-20 00:00:00

  • The outcome of pediatric patients undergoing congenital cardiac surgery under pulsatile cardiopulmonary bypass in different frequencies.

    abstract:Purpose:To investigate the influence and possible pathophysiological mechanism of pulsatile cardiopulmonary bypass (CPB) in various frequencies in pediatric patients undergoing congenital cardiac surgery. Patients and methods:Clinical data and hemodynamic parameters were collected in 80 patients who underwent congenit...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S170642

    authors: Li G,Jiang W,Zhang Y,Zhang X,Chen J,Zhuang J,Zhou C

    更新日期:2018-09-03 00:00:00

  • Efficacy versus safety: the dilemma of using novel platelet inhibitors for the treatment of patients with ischemic stroke and coronary artery disease.

    abstract::Coronary and cerebrovascular atherothrombosis are the leading cause of mortality and morbidity worldwide. Novel antiplatelet agents have been established for the management of patients with clinically evident coronary atherothrombosis and are increasingly used in these patients. These agents, however, have shown limit...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S39216

    authors: Iannopollo G,Camporotondo R,De Ferrari GM,Leonardi S

    更新日期:2014-05-02 00:00:00

  • Evaluation of external pressure to the sacral region in the lithotomy position using the noninvasive pressure distribution measurement system.

    abstract:BACKGROUND:Pressure ulcers (PUs) in the sacral region can be a complication of surgical procedures performed in the lithotomy position. Previous reports have noted a difference between men and women in PU development related to the supine position, and body weight and body mass index (BMI) have been also described as k...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S122489

    authors: Mizuno J,Takahashi T

    更新日期:2017-02-17 00:00:00

  • Treatment Pattern Analysis and Health-care Resource Consumption on Patients with Psoriatic Arthritis or Ankylosing Spondylitis Treated with Biological Drugs in a Northern Italian Region.

    abstract:Purpose:To analyze the treatment patterns of psoriatic arthritis (PSA) or ankylosing spondylitis (AS) patients under biological therapies and to evaluate in this population the health-care resource consumption and related costs. Patients and Methods:A retrospective analysis was performed on administrative databases of...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S248390

    authors: Perrone V,Giacomini E,Sangiorgi D,Andretta M,Menti AM,Naclerio M,Ritrovato D,Degli Esposti L

    更新日期:2020-06-09 00:00:00

  • Critical appraisal and clinical utility of atosiban in the management of preterm labor.

    abstract::Preterm birth is the major cause of perinatal morbidity and mortality in the developed world, and spontaneous preterm labor is the commonest cause of preterm birth. Interventions to treat women in spontaneous preterm labor have not reduced the incidence of preterm births but this may be due to increased risk factors, ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s9378

    authors: Sanu O,Lamont RF

    更新日期:2010-04-26 00:00:00

  • Dexmedetomidine reduces sevoflurane EC50 for supraglottic airway device insertion in spontaneously breathing morbidly obese patients.

    abstract::Purpose: This study aimed to assess the effect of intravenous dexmedetomidine (DEX) on sevoflurane EC50 for supraglottic airway device (SAD) insertion in spontaneously breathing morbidly obese patients. Patients and methods: Thirty-eight morbidly obese patients with a body mass index 40-57 kg/m2 who were scheduled for...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S199440

    authors: Wan L,Shao LJ,Liu Y,Wang HX,Xue FS,Tian M

    更新日期:2019-05-03 00:00:00

  • Topotecan: An evolving option in the treatment of relapsed small cell lung cancer.

    abstract::The topoisomerase I inhibitor topotecan is the only single-agent therapy approved for the treatment of recurrent small cell lung cancer (SCLC). Many patients with recurrent SCLC may be predisposed to treatment-related adverse events because of the presence of comorbidities such as advanced age, renal impairment, or ex...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:

    authors: Garst J

    更新日期:2007-12-01 00:00:00

  • Severe complications after negative pressure wound therapy in burned wounds: two case reports.

    abstract::We present two typical cases of severe complications (sepsis and hemorrhage) after negative pressure wound therapy (NPWT) in burned patients. Necrotic tissues in some deep burn wounds are difficult to judge correctly and remove thoroughly. An electrically burned blood vessel looks "intact" but can easily break. Necrot...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S66117

    authors: Ren H,Li Y

    更新日期:2014-07-01 00:00:00