Udenafil for the treatment of erectile dysfunction.

abstract：:Background: To report our experience with retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys. Methods: We retrospectively reviewed the medical records of 7 patients who underwent retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy at our inst...

journal_title：Therapeutics and clinical risk management

authors： Qin J,Wang P,Jing T,Kong D,Ye S,Xia D,Wang S

更新日期：2019-06-11 00:00:00

abstract：:Glucocorticoids are commonly used in various fields within medicine. One of their most common and clinically significant side effects is glucocorticoid-induced osteoporosis (GIOP). GIOP is a disease leading to progressive decreases in bone mineral density, decreased bone strength, and increased risk of skeletal fractu...

journal_title：Therapeutics and clinical risk management

authors： Lau AN,Adachi JD

更新日期：2010-10-21 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a chronic disease that affects 14.2% of the US adult population. Despite being widespread, little is known about the etiology of CRS. Treatment has been symptomatic and focused on relieving symptoms. Recent investigations into causes of CRS have revealed that most CRS patients have an e...

journal_title：Therapeutics and clinical risk management

authors： Kern EB,Sherris D,Stergiou AM,Katz LM,Rosenblatt LC,Ponikau J

更新日期：2007-06-01 00:00:00

abstract：:Therapy of soft tissue sarcomas represents an area of significant unmet need in oncology. Angiogenesis has been explored as a potential target both preclinically and clinically, with suggestions of activity. Pazopanib is a multitargeted tyrosine kinase inhibitor with prominent antiangiogenic effects. In a Phase II stu...

journal_title：Therapeutics and clinical risk management

authors： Cranmer LD,Loggers ET,Pollack SM

更新日期：2016-06-09 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative, dopamine deficiency disorder. The main therapeutic strategies for PD treatment relies on dopamine precursors (levodopa), inhibition of dopamine metabolism (monoamine oxidase [MAO] B and catechol-O-methyl transferase inhibitors), and dopamine receptor agonist...

journal_title：Therapeutics and clinical risk management

authors： Lecht S,Haroutiunian S,Hoffman A,Lazarovici P

更新日期：2007-06-01 00:00:00

abstract：:The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the alpha(1a) and alpha(1d) adrenergic receptor subtypes. The oral-controlled absorption system (OCAS((R))) represents a drug delivery refinement that incorporates a matrix of gel-f...

journal_title：Therapeutics and clinical risk management

authors： Neill MG,Shahani R,Zlotta AR

更新日期：2008-02-01 00:00:00

abstract：:Hyperphosphatemia is an inevitable consequence of end stage chronic kidney disease and is present in the majority of dialysis patients. Recent observational data has associated hyperphosphatemia with increased cardiovascular mortality among dialysis patients. Dietary restriction of phosphate and current dialysis presc...

journal_title：Therapeutics and clinical risk management

authors： Mohammed IA,Hutchison AJ

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The outcome of decompressive craniectomy (DC) for severe traumatic brain injury (sTBI) patients with fixed dilated pupils (FDPs) is not clear. The objective of this study was to validate the outcome of DC in sTBI patients with FDPs. PATIENTS:We retrospectively collected data from 207 sTBI patients with FDPs ...

journal_title：Therapeutics and clinical risk management

authors： Mao X,Miao G,Hao S,Tao X,Hou Z,Li H,Tian R,Zhang H,Lu T,Ma J,Zhang X,Cheng H,Liu B

更新日期：2015-10-22 00:00:00

abstract：Background:Hydroxychloroquine (HCQ), one of the disease-modifying antirheumatic drugs, may lead to an inhibition of autophagy. Autophagy, an intracellular self-defense mechanism for the lysosomal degradation of cytoplasmic components such as damaged organelles, plays a role in protecting against neoplasm growth but is ...

journal_title：Therapeutics and clinical risk management

authors： Mao IC,Lin CY,Wu CL,Kor CT,Chang CC

更新日期：2018-08-20 00:00:00

abstract：:Treatment of HIV-1 infection has produced dramatic success for many patients. Nevertheless, viral resistance continues to limit the efficacy of currently available agents in many patients. The CCR5 antagonists are a new class of antiretroviral agents that target a necessary coreceptor for viral entry of many strains o...

journal_title：Therapeutics and clinical risk management

authors： Schlecht HP,Schellhorn S,Dezube BJ,Jacobson JM

更新日期：2008-04-01 00:00:00

abstract：:The management of acute episodes in schizophrenia is frequently initiated in the psychiatric emergency department and requires rapid intervention to relieve distress and psychiatric symptoms. Both non-pharmacological and pharmacological interventions are needed to calm the patient and prevent potential harm to the pat...

journal_title：Therapeutics and clinical risk management

authors： Nuss P,Hummer M,Tessier C

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Acute heart failure (AHF) is a serious condition that is associated with increased mortality in critically ill patients. Previous studies indicated that environmental exposure to cadmium increases mortality of general populations. However, the relationship of cadmium exposure and mortality is unclear for AHF...

journal_title：Therapeutics and clinical risk management

authors： Hsu CW,Weng CH,Lee CC,Lin-Tan DT,Chu PH,Chen KH,Yen TH,Huang WH

更新日期：2017-03-27 00:00:00

abstract：:Over recent decades, basic research has yielded a large volume of data on many potentially clinically relevant genetic determinants of drug efficacy and toxicity. Until recently, most examples involved genes encoding drug-metabolizing enzymes, particularly the cytochromes P450. More recently, rapid advances in genomic...

journal_title：Therapeutics and clinical risk management

authors： McKinnon RA,Ward MB,Sorich MJ

更新日期：2007-10-01 00:00:00

abstract：INTRODUCTION:Copeptin which is the C-terminal fragment of antidiuretic hormone (ADH), is a biomarker that has been reported to be increased in various cardiovascular disorders, cerebrovascular diseases and associated with prognosis. Patients with obstructive sleep apnea syndrome (OSAS) have a tendency to develop corona...

journal_title：Therapeutics and clinical risk management

authors： Çınarka H,Kayhan S,Karataş M,Yavuz A,Gümüş A,Özyurt S,Cüre MC,Şahin Ü

更新日期：2015-04-10 00:00:00

abstract：Background:Liver cirrhosis is an uncommon but not rare side effect of amiodarone-induced hepatotoxicity. Patients with hepatitis B virus and hepatitis C virus infections are at a high risk for developing liver cirrhosis. However, the relationship between this treatment and risk of liver cirrhosis in high-risk chronic h...

journal_title：Therapeutics and clinical risk management

authors： Huang CH,Lai YY,Kuo YJ,Yang SC,Chang YJ,Chang KK,Chen WK

更新日期：2019-01-10 00:00:00

abstract：:Soft tissue sarcomas (STSs) are a group of rare tumors accounting for less than 1% of all adult malignant tumors, a heterogeneous group of more than 50 histological subtypes. Five percent to 30% of STS patients experience local recurrence and 10%-38% present with clinically detectable metastases. Doxorubicin either al...

journal_title：Therapeutics and clinical risk management

authors： Nakamura T,Matsumine A,Sudo A

更新日期：2016-01-13 00:00:00

abstract：Purpose:We aimed to build a model to qualitatively and quantitatively evaluate publications of research of spinal cord injury rehabilitation from 1997 to 2016. Methods:Data were obtained from the Web of Science Core Collection on October 6, 2017. We conducted a qualitative and quantitative analysis of publication outp...

journal_title：Therapeutics and clinical risk management

authors： Liu X,Liu N,Zhou M,Lu Y,Li F

更新日期：2018-12-17 00:00:00

abstract：:We present here the case of a 33-year-old Chinese female patient with synchronous double primary malignant tumors (chronic myeloid leukemia [CML] and classic Hodgkin lymphoma). This patient was admitted to our hospital because of bilateral cervical lymph node enlargement and recurrent fever for 2 weeks. The complete b...

journal_title：Therapeutics and clinical risk management

authors： Liu Z,Li S,Bai O

更新日期：2017-09-05 00:00:00

abstract：:Angioid streaks are visible irregular crack-like dehiscences in Bruch's membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget's disease, sickle-cell anemia, acromegaly, Ehlers-Danlos syndrome, and di...

journal_title：Therapeutics and clinical risk management

authors： Georgalas I,Papaconstantinou D,Koutsandrea C,Kalantzis G,Karagiannis D,Georgopoulos G,Ladas I

更新日期：2009-02-01 00:00:00

abstract：:The C-MAC videolaryngoscope was evaluated for intubation in patients with predicted extremely difficult airway. The presented cases are patients with neoplasm tumors in larynx. In all cases, awake intubation using C-MAC videolaryngoscope was performed in patients breathing spontaneously, under local anaesthesia, with ...

journal_title：Therapeutics and clinical risk management

authors： Gaszyński T

更新日期：2018-03-14 00:00:00

abstract：BACKGROUND:The aim of this open-label, randomized, parallel-group pilot study was to evaluate the efficacy of cefditoren pivoxil and levofloxacin in terms of speed of reduction in inflammatory parameters, clinical recovery, and microbiological eradication. METHODS:Forty eligible patients with acute exacerbation of chr...

journal_title：Therapeutics and clinical risk management

authors： Blasi F,Tarsia P,Mantero M,Morlacchi LC,Piffer F

更新日期：2013-01-01 00:00:00

abstract：Background:Cardiovascular diseases (CVDs) are the main complication leading to morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). There is a large amount of evidence to support the use of lipid-lowering therapy (LLT) for the prevention of CVD. This study aimed to assess the effectiveness and p...

journal_title：Therapeutics and clinical risk management

authors： Elnaem MH,Mohamed MHN,Huri HZ,Shah ASM

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Developmental dysplasia of the hip joint is one of the most common congenital defects and often results in functional and structural disorders. Such cases particularly demand optimizing therapeutic effects and maximally reducing the duration of therapy. PURPOSE:The aim of this case report is to present the ...

journal_title：Therapeutics and clinical risk management

authors： Kiebzak W,Żurawski A,Dwornik M

更新日期：2016-08-19 00:00:00

abstract：BACKGROUND:Adverse drug reactions are important determinants of inpatient and outpatient morbidity. Thiocolchicoside is a semisynthetic derivate of naturally occurring colchicoside, which is largely used in humans as a centrally acting muscle relaxant. Epileptic seizures after thiocolchicoside intake have been reported...

journal_title：Therapeutics and clinical risk management

authors： Giavina-Bianchi P,Giavina-Bianchi M,Tanno LK,Ensina LF,Motta AA,Kalil J

更新日期：2009-06-01 00:00:00

abstract：:Angiogenesis is an essential process in the development, growth, and metastasis of malignant tumors including lung cancer. Several angiogenesis inhibitors have been developed as potential therapies for non-small-cell lung cancer (NSCLC). Nintedanib is a small-molecule tyrosine kinase inhibitor that targets receptors f...

journal_title：Therapeutics and clinical risk management

authors： Takeda M,Okamoto I,Nakagawa K

更新日期：2015-11-16 00:00:00

abstract：BACKGROUND:Multifactor cardiovascular disease is the leading cause of death; besides well-known cardiovascular risk factors, several emerging factors such as mental stress, diet type, and physical inactivity, have been associated to cardiovascular disease. To date, preventive strategies are based on the concept of abso...

journal_title：Therapeutics and clinical risk management

authors： Franchi D,Cini D,Iervasi G

更新日期：2011-01-01 00:00:00

abstract：:Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage. AKs have historically been characterized as being "precancerous"; however, now it is considered by many author...

journal_title：Therapeutics and clinical risk management

authors： Skroza N,Bernardini N,Proietti I,Potenza C

更新日期：2018-10-04 00:00:00

abstract：:The development of nonsteroidal anti-inflammatory drugs (NSAIDs) selective for cyclooxygenase (COX)-2 (named coxibs) has been driven by the aim of reducing the incidence of serious gastrointestinal (GI) adverse events associated with the administration of traditional (t) NSAIDs - mainly dependent on the inhibition of ...

journal_title：Therapeutics and clinical risk management

authors： Patrignani P,Tacconelli S,Capone ML

更新日期：2008-10-01 00:00:00

abstract：Purpose:Almost all of the publications regarding the treatment of biliary complications after liver transplantation are related to biliary complications after right lobe living donor liver transplantation (LDLT) and cadaveric liver transplantation (LT). The number of publications regarding endoscopic treatment of bilia...

journal_title：Therapeutics and clinical risk management

authors： Erdogan MA,Harputluoglu MM

更新日期：2018-10-17 00:00:00

abstract：:A "Meeting on Upstream Rotavirus Vaccines and Emerging Vaccine Producers" was held at the World Health Organization in Geneva, Switzerland on March 28-30, 2006. The purpose was to discuss, evaluate, and weigh the importance of additional rotavirus vaccine candidates following the successful international licensure of ...

journal_title：Therapeutics and clinical risk management

authors： Ward RL,McNeal MM,Steele AD

更新日期：2008-02-01 00:00:00