Swollen lymph nodes may not be clinical manifestations of chronic myeloid leukemia: case report and revision of literature.

abstract：:Staphylococcus aureus bacteremia is a common disease with a high risk of mortality and complications. An increasing proportion of cases are methicillin-resistant S.aureus (MRSA), and methicillin-resistance is being observed from both community-acquired bacteremias and in healthcare-associated infections. The duration ...

journal_title：Therapeutics and clinical risk management

authors： Bamberger DM

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The aims of this study were to explore the correlation between chronic hepatitis B virus (HBV) drug-resistant mutation profiles and the efficacy of nucleoside analog rescue therapy in patients with initial antiviral treatment failure. PATIENTS AND METHODS:Patients with initial antiviral therapy fai...

journal_title：Therapeutics and clinical risk management

authors： Liang LB,Chen LL,Chen EQ,Liao J,Tang H

更新日期：2015-03-12 00:00:00

abstract：:The treatment of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) positively changed since the introduction of anti-TNFα drugs. These treatments were shown to reduce the symptoms and signs of the diseases and improve the quality of life. However, a variable percentage of patients do not respond to anti-TNFα o...

journal_title：Therapeutics and clinical risk management

authors： Lubrano E,Perrotta FM

更新日期：2016-10-21 00:00:00

abstract：AIM:The aim of this study was to evaluate the efficacy of, and patients' subjective responses to, periodontal ligament (PDL) anesthetic injection compared to traditional local-anesthetic infiltration injection for the nonsurgical extraction of one posterior maxillary permanent tooth. MATERIALS AND METHODS:All patients...

journal_title：Therapeutics and clinical risk management

authors： Al-Shayyab MH

更新日期：2017-10-06 00:00:00

abstract：Purpose:We aimed to present our experience with total hip arthroplasty in patients with previous hip arthrodesis. Patients and methods:This was a retrospective study, in which clinical and radiological outcomes of total hip arthroplasty performed in 17 patients (mean age 54.2±8.5 years; age range 33-68 years; female t...

journal_title：Therapeutics and clinical risk management

authors： Çalbıyık M

更新日期：2018-04-11 00:00:00

abstract：INTRODUCTION:Copeptin which is the C-terminal fragment of antidiuretic hormone (ADH), is a biomarker that has been reported to be increased in various cardiovascular disorders, cerebrovascular diseases and associated with prognosis. Patients with obstructive sleep apnea syndrome (OSAS) have a tendency to develop corona...

journal_title：Therapeutics and clinical risk management

authors： Çınarka H,Kayhan S,Karataş M,Yavuz A,Gümüş A,Özyurt S,Cüre MC,Şahin Ü

更新日期：2015-04-10 00:00:00

abstract：Purpose:To determine the early effects of intravitreal anti-VEGF and dexamethasone application on blood flow velocities in patients with retinal vein occlusions. Methods:The ophthalmic (OA) and the central retinal arteries (CRAs) of the affected and unaffected eyes of 21 patients with central retinal vein occlusion (C...

journal_title：Therapeutics and clinical risk management

authors： Ciloglu E,Yıldırım Celikdemir A

更新日期：2019-07-04 00:00:00

abstract：Purpose:To investigate the influence and possible pathophysiological mechanism of pulsatile cardiopulmonary bypass (CPB) in various frequencies in pediatric patients undergoing congenital cardiac surgery. Patients and methods:Clinical data and hemodynamic parameters were collected in 80 patients who underwent congenit...

journal_title：Therapeutics and clinical risk management

authors： Li G,Jiang W,Zhang Y,Zhang X,Chen J,Zhuang J,Zhou C

更新日期：2018-09-03 00:00:00

abstract：:Angiogenesis is an essential process in the development, growth, and metastasis of malignant tumors including lung cancer. Several angiogenesis inhibitors have been developed as potential therapies for non-small-cell lung cancer (NSCLC). Nintedanib is a small-molecule tyrosine kinase inhibitor that targets receptors f...

journal_title：Therapeutics and clinical risk management

authors： Takeda M,Okamoto I,Nakagawa K

更新日期：2015-11-16 00:00:00

abstract：:Therapy of soft tissue sarcomas represents an area of significant unmet need in oncology. Angiogenesis has been explored as a potential target both preclinically and clinically, with suggestions of activity. Pazopanib is a multitargeted tyrosine kinase inhibitor with prominent antiangiogenic effects. In a Phase II stu...

journal_title：Therapeutics and clinical risk management

authors： Cranmer LD,Loggers ET,Pollack SM

更新日期：2016-06-09 00:00:00

abstract：AIM:To compare the long-term survival outcomes of radiofrequency ablation and liver resection for single very early/early stage hepatocellular carcinoma (HCC). METHODS:The Cochrane Library (Issue 3, 2015), Embase (1974 to March 15, 2015), PubMed (1950 to March 15, 2015), Web of Science (1900 to March 15, 2015), and Ch...

journal_title：Therapeutics and clinical risk management

authors： He ZX,Xiang P,Gong JP,Cheng NS,Zhang W

更新日期：2016-02-23 00:00:00

abstract：Background:Our aim was to investigate the postoperative analgesic effect of ultrasound (US)-guided bilateral transversus abdominis plane (TAP) blocks combined with rectus sheath blocks (RSBs) in laparoscopic hepatectomy. Patients and Methods:A total of 126 patients were allocated into two groups for analysis. Group 1 ...

journal_title：Therapeutics and clinical risk management

authors： Lu X,Yu P,Ou C,Wang J,Zhou Z,Lai R

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Artemether-lumefantrine (AL) has been used as a first-line treatment for uncomplicated Plasmodium falciparum malaria in Ethiopia since 2004. Antimalarial drug resistance is one of the major obstacles for malaria control and curtails the lifespan of several drugs. Thus, continued monitoring of the efficacy of...

journal_title：Therapeutics and clinical risk management

authors： Deressa T,Seid ME,Birhan W,Aleka Y,Tebeje BM

更新日期：2017-02-16 00:00:00

abstract：BACKGROUND:Iron-deficiency anemia is the most common nutritional cause of anemia in pregnancy and is often responsible for puerperal anemia. Puerperal anemia can impair postpartum maternal and neonatal well-being. OBJECTIVE:To determine the effect of treatment of moderate puerperal iron-deficiency anemia using a singl...

journal_title：Therapeutics and clinical risk management

authors： Iyoke CA,Emegoakor FC,Ezugwu EC,Lawani LO,Ajah LO,Madu JA,Ezegwui HU,Ezugwu FO

更新日期：2017-05-17 00:00:00

abstract：:Allergic rhinitis and urticaria are common allergic diseases that may have a major negative impact on patients' quality of life. Bilastine, a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. This agent does not interact with ...

journal_title：Therapeutics and clinical risk management

authors： Wang XY,Lim-Jurado M,Prepageran N,Tantilipikorn P,Wang de Y

更新日期：2016-04-13 00:00:00

abstract：:Paclitaxel is an anticancer agent effective for the treatment of breast, ovarian, lung, and head and neck cancer. Because of water insolubility, paclitaxel is formulated with the micelle-forming vehicle Cremophor EL to enhance drug solubility. However, the addition of Cremophor EL results in hypersensitivity reactions...

journal_title：Therapeutics and clinical risk management

authors： Scripture CD,Figg WD,Sparreboom A

更新日期：2005-06-01 00:00:00

abstract：:Over recent decades, basic research has yielded a large volume of data on many potentially clinically relevant genetic determinants of drug efficacy and toxicity. Until recently, most examples involved genes encoding drug-metabolizing enzymes, particularly the cytochromes P450. More recently, rapid advances in genomic...

journal_title：Therapeutics and clinical risk management

authors： McKinnon RA,Ward MB,Sorich MJ

更新日期：2007-10-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative, dopamine deficiency disorder. The main therapeutic strategies for PD treatment relies on dopamine precursors (levodopa), inhibition of dopamine metabolism (monoamine oxidase [MAO] B and catechol-O-methyl transferase inhibitors), and dopamine receptor agonist...

journal_title：Therapeutics and clinical risk management

authors： Lecht S,Haroutiunian S,Hoffman A,Lazarovici P

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:We carried out an economic analysis to assess the cost-effectiveness of highly active antiretroviral therapy (HAART) regimens in Italy for the management of human immunodeficiency virus (HIV)-infected patients according to clinical practice in the Infectious Diseases Department of "L. Sacco" Hospital, Mila...

journal_title：Therapeutics and clinical risk management

authors： Rizzardini G,Bonfanti P,Carenzi L,Coen M,Orlando G,Di Matteo S,Colombo GL

更新日期：2012-01-01 00:00:00

abstract：:A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act) cycle was used for continuous quality improvement. The proportio...

journal_title：Therapeutics and clinical risk management

authors： Zhu LL,Xu LC,Wang HQ,Jin JF,Wang HF,Zhou Q

更新日期：2012-01-01 00:00:00

abstract：:Poorly controlled asthma is currently treated by adding or removing asthma medication in a stepwise fashion to try and improve symptoms and maintain lung function. It is becoming apparent that asthma exacerbations are independent of asthma control and severity, and that the simple method of using rescue courses of cor...

journal_title：Therapeutics and clinical risk management

authors： Shaw DE,Green RH,Bradding P

更新日期：2005-12-01 00:00:00

abstract：:Prostacyclin is an endogenous eicosanoid produced by endothelial cells; through actions on vascular smooth-muscle cells, it promotes vasodilation. Pulmonary arterial hypertension (PAH) is characterized by elevated mean pulmonary artery pressure due to a high pulmonary vascular resistance state. A relative decrease in ...

journal_title：Therapeutics and clinical risk management

authors： LeVarge BL

更新日期：2015-03-31 00:00:00

abstract：Background:Although complications have been associated with head clamp systems, few reports have described head slippage. The present study aimed to determine risk factors for head slippage and speculated that the position of head holder pins might be associated. Patients and Methods:We reviewed medical records and co...

journal_title：Therapeutics and clinical risk management

authors： Sakakura K,Fujimoto A,Ichikawa N,Ishikawa E,Matsumura A,Enoki H,Okanishi T

更新日期：2020-03-25 00:00:00

abstract：:Trichosporon asahii is an emerging opportunistic pathogen that is life-threatening particularly for immunosuppressed patients. Only a few studies have described Trichosporon infection in kidney transplant recipients. This study reports a 67-year-old male kidney transplant recipient who developed fatal fungemia and pne...

journal_title：Therapeutics and clinical risk management

authors： Yang MF,Gao HN,Li LJ

更新日期：2014-09-30 00:00:00

abstract：:Patients with cancer have a 6-7-fold higher risk of venous thromboembolism (VTE) as compared with non-cancer patients. Effective and safe anticoagulation for the prevention and treatment of VTE is the cornerstone of the management of patients with cancer, aiming to decrease morbidity and mortality and to improve quali...

journal_title：Therapeutics and clinical risk management

authors： Gerotziafas GT,Mahé I,Elalamy I

更新日期：2014-06-13 00:00:00

abstract：:Antimicrobial agents are the most valuable means available for treating bacterial infections. However, the administration of therapeutic doses of antimicrobial agents to patients is a leading cause of disturbance of the normal gastrointestinal microflora. This disturbance results in diminishing the natural defense mec...

journal_title：Therapeutics and clinical risk management

authors： Rafii F,Sutherland JB,Cerniglia CE

更新日期：2008-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) management in the transplant setting is still an open issue. The therapeutic strategies being addressed include: (a) pre-transplant prophylaxis (to prevent the infection of the transplanted organ); (b) post-transplant prophylaxis (to reduce the possibility of developing acute hepatitis); (c) ma...

journal_title：Therapeutics and clinical risk management

authors： Picciotto A

更新日期：2006-03-01 00:00:00

abstract：:The management of acute episodes in schizophrenia is frequently initiated in the psychiatric emergency department and requires rapid intervention to relieve distress and psychiatric symptoms. Both non-pharmacological and pharmacological interventions are needed to calm the patient and prevent potential harm to the pat...

journal_title：Therapeutics and clinical risk management

authors： Nuss P,Hummer M,Tessier C

更新日期：2007-03-01 00:00:00

abstract：:Bazedoxifene acetate is a novel, chemically distinct selective estrogen receptor modulator (SERM) that has been specifically developed after a stringent preclinical screening in order to obtain favorable effects on the skeleton and lipid metabolism with the additional improvement of a neutral effect on hot flushes and...

journal_title：Therapeutics and clinical risk management

authors： Gennari L,Merlotti D,De Paola V,Martini G,Nuti R

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND/PURPOSE:In-hospital mortality rate of acute ischemic stroke patients remains between 3% and 18%. For improving the quality of stroke care, we investigated the factors that contribute to the risk of in-hospital mortality in acute ischemic stroke patients. MATERIALS AND METHODS:Between January 1, 2007, and De...

journal_title：Therapeutics and clinical risk management

authors： Ong CT,Wong YS,Wu CS,Su YH

更新日期：2016-06-29 00:00:00