Comparative study on drug safety surveillance between medical students of Malaysia and Nigeria.

abstract：:Purpose: This study aimed to assess the effect of intravenous dexmedetomidine (DEX) on sevoflurane EC50 for supraglottic airway device (SAD) insertion in spontaneously breathing morbidly obese patients. Patients and methods: Thirty-eight morbidly obese patients with a body mass index 40-57 kg/m2 who were scheduled for...

journal_title：Therapeutics and clinical risk management

authors： Wan L,Shao LJ,Liu Y,Wang HX,Xue FS,Tian M

更新日期：2019-05-03 00:00:00

abstract：:Erectile dysfunction (ED) is often perceived by both patients and sexual partners as a serious problem that can jeopardize quality of life, psychosocial or emotional well-being, and the partnership in the long term. Since their introduction, oral phosphodiesterase type 5 inhibitors (PDE5Is) have been found to be highl...

journal_title：Therapeutics and clinical risk management

authors： Cho MC,Paick JS

更新日期：2014-05-14 00:00:00

abstract：Purpose:Pharmacological errors are among the most common in the healthcare system. This study aimed to determine the level of safety of the pharmacotherapy process at the stage performed by nurses and midwives by indicating the key risk factors affecting patients' safety. Methods:A group of 1276 nurses and 136 midwive...

journal_title：Therapeutics and clinical risk management

authors： Witczak I,Uchmanowicz I,Tartaglia R,Rypicz Ł

更新日期：2020-11-04 00:00:00

abstract：:Chronic cancer and nonmalignant pain (CNMP) is a common and major health problem afflicting approximately 40 million persons in the US. Most cancer patients, and many patients with CNMP, require opioid analgesics to obtain adequate pain relief. Oral oxymorphone is a new formulation of an existing parenteral opioid tha...

journal_title：Therapeutics and clinical risk management

authors： Sloan P

更新日期：2008-08-01 00:00:00

abstract：Background:Wells and Geneva scores are widely used in the assessment of pretest probability of pulmonary embolism (PE). Objective:The objective of this study was to examine the hypothesis that mean platelet volume (MPV) may better predict PE than the clinical prediction rules. Methods:A study was performed among pati...

journal_title：Therapeutics and clinical risk management

authors： Lipinska A,Ledakowicz-Polak A,Krauza G,Przybylak K,Zielinska M

更新日期：2018-11-09 00:00:00

abstract：Background:Hyperparathyroidism is a frequent endocrine disorder with variable clinical manifestations and outcomes. We aimed to evaluate clinical presentations, management and outcomes of hyperparathyroidism. Methods:A retrospective study was conducted to include all patients presented with hyperparathyroidism between...

journal_title：Therapeutics and clinical risk management

authors： Al-Thani H,El-Matbouly M,Al-Sulaiti M,Asim M,Majzoub A,Tabeb A,El-Menyar A

更新日期：2018-07-31 00:00:00

abstract：:The most frequent causes of leg ulcers are chronic venous disease (CVD) related mainly to venous hypertension and peripheral arterial disease (PAD) related to disseminated atheromatous lesions in lower limb arteries. In 15%-21% of patients, ulcers of mixed venous-arterial etiology occur, which are usually more resista...

journal_title：Therapeutics and clinical risk management

authors： Pasek J,Cieślar G,Sieroń A

更新日期：2018-10-08 00:00:00

abstract：BACKGROUND:Multifactor cardiovascular disease is the leading cause of death; besides well-known cardiovascular risk factors, several emerging factors such as mental stress, diet type, and physical inactivity, have been associated to cardiovascular disease. To date, preventive strategies are based on the concept of abso...

journal_title：Therapeutics and clinical risk management

authors： Franchi D,Cini D,Iervasi G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:This retrospective cohort study evaluated whether manual lymphatic drainage (MLD) therapy increases the risk of recurrence of breast cancer. METHODS:We analyzed 1,106 women who were diagnosed with stage 0-3 breast cancer between 2007 and 2011 and experienced remission after surgery and adjuvant therapy. The...

journal_title：Therapeutics and clinical risk management

authors： Hsiao PC,Liu JT,Lin CL,Chou W,Lu SR

更新日期：2015-02-27 00:00:00

abstract：BACKGROUND:This study aims to investigate differences between continuous epidural infusion (CEI) and programmed intermittent epidural bolus (IEB) analgesia for the Chinese parturients undergoing spontaneous delivery and to approach their safety to parturients and neonates. METHODS:Two hundred healthy American Society ...

journal_title：Therapeutics and clinical risk management

authors： Lin Y,Li Q,Liu J,Yang R,Liu J

更新日期：2016-07-14 00:00:00

abstract：:The topoisomerase I inhibitor topotecan is the only single-agent therapy approved for the treatment of recurrent small cell lung cancer (SCLC). Many patients with recurrent SCLC may be predisposed to treatment-related adverse events because of the presence of comorbidities such as advanced age, renal impairment, or ex...

journal_title：Therapeutics and clinical risk management

authors： Garst J

更新日期：2007-12-01 00:00:00

abstract：Background:Anesthesia and surgery may deteriorate liver function in patients with elevated liver enzyme levels; therefore, in these patients, choosing anesthetics with less hepatotoxicity is important. Methods:This retrospective study investigated the effect of total intravenous anesthesia (TIVA) versus inhalation ane...

journal_title：Therapeutics and clinical risk management

authors： Oh SK,Lim BG,Kim YS,Kim SS

更新日期：2020-04-05 00:00:00

abstract：:Daptomycin is a novel bactericidal antibiotic with excellent activity against gram-positive organisms. It is a large cyclic lipopeptide with a unique mechanism of action. Daptomycin is given once a day and is renally cleared, requiring dose adjustment in patients with impaired renal function. Unfortunately, there have...

journal_title：Therapeutics and clinical risk management

authors： Shoemaker DM,Simou J,Roland WE

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The aims of this study were to explore the correlation between chronic hepatitis B virus (HBV) drug-resistant mutation profiles and the efficacy of nucleoside analog rescue therapy in patients with initial antiviral treatment failure. PATIENTS AND METHODS:Patients with initial antiviral therapy fai...

journal_title：Therapeutics and clinical risk management

authors： Liang LB,Chen LL,Chen EQ,Liao J,Tang H

更新日期：2015-03-12 00:00:00

abstract：:Allergic rhinitis and urticaria are common allergic diseases that may have a major negative impact on patients' quality of life. Bilastine, a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. This agent does not interact with ...

journal_title：Therapeutics and clinical risk management

authors： Wang XY,Lim-Jurado M,Prepageran N,Tantilipikorn P,Wang de Y

更新日期：2016-04-13 00:00:00

abstract：BACKGROUND:Acute heart failure (AHF) is a serious condition that is associated with increased mortality in critically ill patients. Previous studies indicated that environmental exposure to cadmium increases mortality of general populations. However, the relationship of cadmium exposure and mortality is unclear for AHF...

journal_title：Therapeutics and clinical risk management

authors： Hsu CW,Weng CH,Lee CC,Lin-Tan DT,Chu PH,Chen KH,Yen TH,Huang WH

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Hypertension is a highly prevalent risk factor for cardiovascular disease in patients with type 1 diabetes mellitus. Elevated blood pressure (BP) promotes the development and progression of microvascular complications, eg, nephropathy and retinopathy. The purpose of this study was to identify and detect earl...

journal_title：Therapeutics and clinical risk management

authors： Shalaby NM,Shalaby NM

更新日期：2015-10-05 00:00:00

abstract：:There are a number of oral agents emerging as potential disease-modifying agents in multiple sclerosis (MS). Among these investigational agents, teriflunomide has shown promise in large, multicenter, phase III clinical trials with respect to safety and efficacy in relapsing MS patients, and is the latest disease-modif...

journal_title：Therapeutics and clinical risk management

authors： Oh J,O'Connor PW

更新日期：2013-01-01 00:00:00

abstract：:Trichosporon asahii is an emerging opportunistic pathogen that is life-threatening particularly for immunosuppressed patients. Only a few studies have described Trichosporon infection in kidney transplant recipients. This study reports a 67-year-old male kidney transplant recipient who developed fatal fungemia and pne...

journal_title：Therapeutics and clinical risk management

authors： Yang MF,Gao HN,Li LJ

更新日期：2014-09-30 00:00:00

abstract：:A "Meeting on Upstream Rotavirus Vaccines and Emerging Vaccine Producers" was held at the World Health Organization in Geneva, Switzerland on March 28-30, 2006. The purpose was to discuss, evaluate, and weigh the importance of additional rotavirus vaccine candidates following the successful international licensure of ...

journal_title：Therapeutics and clinical risk management

authors： Ward RL,McNeal MM,Steele AD

更新日期：2008-02-01 00:00:00

abstract：:Lobomycosis is a subcutaneous mycosis of chronic evolution caused by the Lacazia loboi fungus. Its distribution is almost exclusive in the Americas, and it has a particularly high prevalence in the Amazon basin. Cases of lobomycosis have been reported only in dolphins and humans. Its prevalence is higher among men who...

journal_title：Therapeutics and clinical risk management

authors： Francesconi VA,Klein AP,Santos AP,Ramasawmy R,Francesconi F

更新日期：2014-10-09 00:00:00

abstract：:COVID-19 pandemic is inducing acute respiratory distress syndrome, multi-organ failure, and eventual death. Respiratory failure is the leading cause of mortality in the elderly population with pre-existing medical conditions. This group is particularly vulnerable to infections due to a declined immune system, comorbid...

journal_title：Therapeutics and clinical risk management

authors： Rahman S,Singh K,Dhingra S,Charan J,Sharma P,Islam S,Jahan D,Iskandar K,Samad N,Haque M

更新日期：2020-10-20 00:00:00

abstract：:A number of drugs rely on the kidney for excretion and thus require their dose to be modified in any patients where there is renal impairment. Others are nephrotoxic and should be avoided completely in patients with renal disease. Traditionally clinicians have had to rely on serum creatinine to assess renal function b...

journal_title：Therapeutics and clinical risk management

authors： Harris K,Stribling B

更新日期：2007-10-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is highly endemic in certain regions including the People's Republic of China and Southeast Asia. Its etiology is unique and multifactorial, involving genetic background, epigenetic, and environment factors, including Epstein-Barr virus (EBV) infection. The presence of EBV in all tumor c...

journal_title：Therapeutics and clinical risk management

authors： Hutajulu SH,Kurnianda J,Tan IB,Middeldorp JM

更新日期：2014-09-05 00:00:00

abstract：Purpose:To analyze the treatment patterns of psoriatic arthritis (PSA) or ankylosing spondylitis (AS) patients under biological therapies and to evaluate in this population the health-care resource consumption and related costs. Patients and Methods:A retrospective analysis was performed on administrative databases of...

journal_title：Therapeutics and clinical risk management

authors： Perrone V,Giacomini E,Sangiorgi D,Andretta M,Menti AM,Naclerio M,Ritrovato D,Degli Esposti L

更新日期：2020-06-09 00:00:00

abstract：Background:Treatment-related problems (TRPs) may pose risks for patients if unaddressed. With the increased complexity of health care, it is important to target pharmacists' efforts to patients that are at high risk for TRPs. Objectives:The present study aimed to identify medications most commonly associated with TRPs...

journal_title：Therapeutics and clinical risk management

authors： Al-Taani GM,Al-Azzam SI,Alzoubi KH,Aldeyab MA

更新日期：2018-11-16 00:00:00

abstract：:Cetuximab is a monoclonal antibody able to inhibit and to degrade the transmembrane receptor Her-1, also known as epidermal growth factor receptor (EGFR). The inhibition of EGFR is of major importance since the receptor influences many important tumor cell activities including tumor growth, neo-angiogenesis, inhibitio...

journal_title：Therapeutics and clinical risk management

authors： Merlano M,Occelli M

更新日期：2007-10-01 00:00:00

abstract：:Japanese encephalitis (JE) is one of severe viral encephalitis that affects individuals in Asia, western Pacific countries, and northern Australia. Although 67,900 JE cases have been estimated among 24 JE epidemic countries annually, only 10,426 have been reported in 2011. With the establishment of JE surveillance and...

journal_title：Therapeutics and clinical risk management

authors： Wang H,Liang G

更新日期：2015-03-19 00:00:00

abstract：OBJECTIVE:To determine the influence of various patient-specific factors, use of concomitant medications, and weekly vitamin K intake on total weekly warfarin maintenance dose (TWD). METHODS:Information collected, via retrospective chart review, included TWD, general demographics, vitamin K consumption, target INR ran...

journal_title：Therapeutics and clinical risk management

authors： Whitley HP,Fermo JD,Chumney EC,Brzezinski WA

更新日期：2007-06-01 00:00:00

abstract：Objective:Retrospective studies and a meta-analysis were performed to evaluate the safety and effectiveness of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP) during cardiac surgery under extracorporeal circulation. Methods:Computerized literature searches were performed in Medl...

journal_title：Therapeutics and clinical risk management

authors： Hua P,Liu J,Tao J,Lin X,Zou R,Zhang D,Yang S

更新日期：2018-02-20 00:00:00