Complex calculation or quick glance? Mean platelet volume - new predictive marker for pulmonary embolism.

abstract：:The application of anthracyclines in anticancer therapy may result in accidental extravasation injury and can be a serious complication of their use. Tissue necrosis with skin ulceration is a possible outcome in the inadvertent extravasation of anthracyclines during intravenous administration. Until recently, there ha...

journal_title：Therapeutics and clinical risk management

authors： Jordan K,Behlendorf T,Mueller F,Schmoll HJ

更新日期：2009-04-01 00:00:00

abstract：:Soft tissue sarcomas (STSs) are a group of rare tumors accounting for less than 1% of all adult malignant tumors, a heterogeneous group of more than 50 histological subtypes. Five percent to 30% of STS patients experience local recurrence and 10%-38% present with clinically detectable metastases. Doxorubicin either al...

journal_title：Therapeutics and clinical risk management

authors： Nakamura T,Matsumine A,Sudo A

更新日期：2016-01-13 00:00:00

abstract：OBJECTIVES:The objective of this study is to mathematically evaluate the influence of multiple factors on implant stability quotient values in clinical practice. PATIENTS AND METHODS:Resonance frequency analysis was performed at T1 (measured immediately at the time of implant placement) and at T2 (measured before dent...

journal_title：Therapeutics and clinical risk management

authors： Huang H,Wismeijer D,Shao X,Wu G

更新日期：2016-10-11 00:00:00

abstract：BACKGROUND:Traditional Chinese medicine (TCM) and Western medicine are both popular in Taiwan. Approximately 14.1% of Taiwanese residents use Western drugs and Chinese herbs concurrently; therefore, drug-herb interaction is critical to patient safety. This paper presents a new procedure for reducing the risk of drug in...

journal_title：Therapeutics and clinical risk management

authors： Lin SS,Tsai CL,Tu CY,Hsieh CL

更新日期：2015-02-16 00:00:00

abstract：Purpose:To compare running suture (RS) and interrupted suture (IS) of vesicourethral anastomosis (VUA) during open retropubic radical prostatectomy (RRP) on early urinary continence and extravasation. Patients and Methods:Single center analysis of 211 patients who underwent RRP performed by a single surgeon during 200...

journal_title：Therapeutics and clinical risk management

authors： Köhler N,El-Bandar N,Maxeiner A,Ralla B,Miller K,Busch J,Friedersdorff F

更新日期：2020-12-23 00:00:00

abstract：Background:Anesthesia and surgery may deteriorate liver function in patients with elevated liver enzyme levels; therefore, in these patients, choosing anesthetics with less hepatotoxicity is important. Methods:This retrospective study investigated the effect of total intravenous anesthesia (TIVA) versus inhalation ane...

journal_title：Therapeutics and clinical risk management

authors： Oh SK,Lim BG,Kim YS,Kim SS

更新日期：2020-04-05 00:00:00

abstract：INTRODUCTION:Copeptin which is the C-terminal fragment of antidiuretic hormone (ADH), is a biomarker that has been reported to be increased in various cardiovascular disorders, cerebrovascular diseases and associated with prognosis. Patients with obstructive sleep apnea syndrome (OSAS) have a tendency to develop corona...

journal_title：Therapeutics and clinical risk management

authors： Çınarka H,Kayhan S,Karataş M,Yavuz A,Gümüş A,Özyurt S,Cüre MC,Şahin Ü

更新日期：2015-04-10 00:00:00

abstract：:Treatment of advanced, recurrent or persistent cervical cancer includes radiotherapy and chemotherapy. Radiation has been the primary treatment modality for locoregionally advanced cervical cancer. Concomitant systemic cisplatin chemotherapy and radiation have shown high response rates with improvements in durable rem...

journal_title：Therapeutics and clinical risk management

authors： Robati M,Holtz D,Dunton CJ

更新日期：2008-02-01 00:00:00

abstract：:Sodium disorders are the most common and most poorly understood electrolyte disorders in neurological patients. The aim of this study was to determine the incidence of sodium disorders and its association with different traumatic brain injuries. This prospective study was conducted in 80 patients diagnosed with modera...

journal_title：Therapeutics and clinical risk management

authors： Paiva WS,Bezerra DA,Amorim RL,Figueiredo EG,Tavares WM,De Andrade AF,Teixeira MJ

更新日期：2011-01-01 00:00:00

abstract：:Cariprazine is a recently developed antipsychotic drug with a partial agonism for the D2 and D3 receptors. It shows a tenfold greater affinity for the D3 receptor. In clinical trials, its therapeutic effect has been tested in patients with an acute exacerbation of schizophrenia and in patients with acute mania in bipo...

journal_title：Therapeutics and clinical risk management

authors： Werner FM,Coveñas R

更新日期：2015-11-02 00:00:00

abstract：INTRODUCTION:Sepsis and septic shock are important causes of mortality in intensive care unit patients, hence early diagnosis and therapy are important in management of their treatment. The available information on sepsis patients is not enough to recommend or to discard the routine evaluation of triglyceride (TG) leve...

journal_title：Therapeutics and clinical risk management

authors： Cetinkaya A,Erden A,Avci D,Karagoz H,Karahan S,Basak M,Bulut K,Gencer V,Mutlu H

更新日期：2014-02-27 00:00:00

abstract：:Eslicarbazepine is a new dibenzazepine antiepileptic agent. It is a high affinity antagonist of the voltage-gated sodium channel. It is closely related to both carbamazepine and oxcarbazepine. Eslicarbazepine has similar affinity to inactivated sodium channels (channels in just activated neurons) as carbamazepine, and...

journal_title：Therapeutics and clinical risk management

authors： Brown ME,El-Mallakh RS

更新日期：2010-04-15 00:00:00

abstract：:The myelodysplastic syndromes (MDS) are a heterogeneous group of disorders that manifest as bone marrow failure with the risk of life threatening infections and bleeding. A third of these patients may transform to acute leukemia. Age and co-morbidities have limited treatment in the majority to supportive care with a m...

journal_title：Therapeutics and clinical risk management

authors： Raj K,Mufti GJ

更新日期：2006-12-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory skin disease that can have a significant impact on the quality of life of those who are afflicted. Recent advances in the understanding of the pathophysiology of psoriasis have led to the development of new, genetically engineered, targeted therapies for this disease. Among...

journal_title：Therapeutics and clinical risk management

authors： Alwawi EA,Mehlis SL,Gordon KB

更新日期：2008-04-01 00:00:00

abstract：:Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduc...

journal_title：Therapeutics and clinical risk management

authors： Ly T,Gulia J,Pyrgos V,Waga M,Shoham S

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Adverse drug reactions are important determinants of inpatient and outpatient morbidity. Thiocolchicoside is a semisynthetic derivate of naturally occurring colchicoside, which is largely used in humans as a centrally acting muscle relaxant. Epileptic seizures after thiocolchicoside intake have been reported...

journal_title：Therapeutics and clinical risk management

authors： Giavina-Bianchi P,Giavina-Bianchi M,Tanno LK,Ensina LF,Motta AA,Kalil J

更新日期：2009-06-01 00:00:00

abstract：:Some specific features of the 24 h blood pressure (BP) pattern are linked to the progressive injury of target tissues and the triggering of cardiac and cerebrovascular events. In particular, many studies show the extent of the nocturnal BP decline relative to the diurnal BP mean (the diurnal/nocturnal ratio, an index ...

journal_title：Therapeutics and clinical risk management

authors： Hermida RC,Ayala DE,Calvo C

更新日期：2007-03-01 00:00:00

abstract：:The introduction of TNFα blockers has revolutionized the treatment of ankylosing spondylitis (AS). The objectives of this review are to summarize the most up-to-date data on long-term efficacy and safety of infliximab in AS, with special emphasis on axial and extra-articular disease, predictors of response, and radiol...

journal_title：Therapeutics and clinical risk management

authors： Elalouf O,Elkayam O

更新日期：2015-11-19 00:00:00

abstract：:We report the case of a 30-year-old Japanese woman with anorexia nervosa and vertebral fractures who was treated with etidronate. She had a history of anorexia nervosa, chronic back pain, osteoporosis, and multiple vertebral fractures (morphometric fractures) that responded poorly to treatment with alfacalcidol (1 μg ...

journal_title：Therapeutics and clinical risk management

authors： Iwamoto J,Sato Y,Uzawa M,Takeda T,Matsumoto H

更新日期：2011-01-01 00:00:00

abstract：:Behçet's disease is an autoinflammatory vasculitis of unknown origin characterized by recurrent oral and genital ulcers, uveitis, arthritis and skin lesions. Additionally, involvement of the gastrointestinal tract, central nervous system and large vessels may occur. The disease is prevalent in countries along the anci...

journal_title：Therapeutics and clinical risk management

authors： van Daele PL,Kappen JH,van Hagen PM,van Laar JA

更新日期：2009-04-01 00:00:00

abstract：:[This corrects the article on p. 19 in vol. 12, PMID: 26730198.]. ...

journal_title：Therapeutics and clinical risk management

authors：

更新日期：2016-03-10 00:00:00

abstract：:The advent of exponential growth of novel agents tested and approved for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) has brought about a need for understanding of the mechanism of action, side-effects, and clinical efficacy of these drugs as they relate to these patients. Thi...

journal_title：Therapeutics and clinical risk management

authors： Patel NK,Finianos A,Whitaker KD,Aragon-Ching JB

更新日期：2014-08-16 00:00:00

abstract：BACKGROUND:Hypertension is a highly prevalent risk factor for cardiovascular disease in patients with type 1 diabetes mellitus. Elevated blood pressure (BP) promotes the development and progression of microvascular complications, eg, nephropathy and retinopathy. The purpose of this study was to identify and detect earl...

journal_title：Therapeutics and clinical risk management

authors： Shalaby NM,Shalaby NM

更新日期：2015-10-05 00:00:00

abstract：:A "Meeting on Upstream Rotavirus Vaccines and Emerging Vaccine Producers" was held at the World Health Organization in Geneva, Switzerland on March 28-30, 2006. The purpose was to discuss, evaluate, and weigh the importance of additional rotavirus vaccine candidates following the successful international licensure of ...

journal_title：Therapeutics and clinical risk management

authors： Ward RL,McNeal MM,Steele AD

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Renal cell carcinoma (RCC) represents 2%-3% of all cancers in adults, and its pathogenesis is mainly related to altered cellular response to hypoxia. Lenvatinib, a novel multitarget tyrosine kinase inhibitor (TKI), represents a therapeutic option, in combination with mammalian target of rapamycin (mTOR) in...

journal_title：Therapeutics and clinical risk management

authors： Leonetti A,Leonardi F,Bersanelli M,Buti S

更新日期：2017-06-30 00:00:00

abstract：:Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS). Pharmacologic options studied for treating severe PMS and PMDD may include selective serotonin reuptake inhibitors, anxiolytic agents, gonadotropin-releasing hormone agonists and the diuretic spironolactone. However, the use of com...

journal_title：Therapeutics and clinical risk management

authors： De Berardis D,Serroni N,Salerno RM,Ferro FM

更新日期：2007-08-01 00:00:00

abstract：:In January 2012, glucarpidase (Voraxaze(®)) received approval from the US Food and Drug Administration for intravenous treatment of toxic plasma methotrexate concentrations due to impaired renal clearance. Methotrexate, an antifolate agent, has been used for over 60 years in the treatment of various cancers. High-dose...

journal_title：Therapeutics and clinical risk management

authors： Green JM

更新日期：2012-01-01 00:00:00

abstract：:A formal risk assessment for identifying high-risk patients is essential in clinical practice and promoted in guidelines for the management of anterior acute myocardial infarction. In this study, we sought to evaluate the performance of different machine learning models in predicting the 1-year mortality rate of anter...

journal_title：Therapeutics and clinical risk management

authors： Li YM,Jiang LC,He JJ,Jia KY,Peng Y,Chen M

更新日期：2020-01-09 00:00:00

abstract：Purpose:Almost all of the publications regarding the treatment of biliary complications after liver transplantation are related to biliary complications after right lobe living donor liver transplantation (LDLT) and cadaveric liver transplantation (LT). The number of publications regarding endoscopic treatment of bilia...

journal_title：Therapeutics and clinical risk management

authors： Erdogan MA,Harputluoglu MM

更新日期：2018-10-17 00:00:00

abstract：Background:Despite the considerable experience gained thus far using endoscopic technologies, the role of total endoscopic thyroidectomy (ET) for papillary thyroid cancer (PTC) remains controversial. We conducted a systematic review and meta-analysis to investigate the safety and effectiveness of total ET compared with...

journal_title：Therapeutics and clinical risk management

authors： Chen C,Huang S,Huang A,Jia Y,Wang J,Mao M,Zhou J,Wang L

更新日期：2018-12-05 00:00:00