The Postoperative Analgesic Effect of Ultrasound-Guided Bilateral Transversus Abdominis Plane Combined with Rectus Sheath Blocks in Laparoscopic Hepatectomy: A Randomized Controlled Study.

Abstract:

Background:Our aim was to investigate the postoperative analgesic effect of ultrasound (US)-guided bilateral transversus abdominis plane (TAP) blocks combined with rectus sheath blocks (RSBs) in laparoscopic hepatectomy. Patients and Methods:A total of 126 patients were allocated into two groups for analysis. Group 1 (n = 63) did not receive any local anesthetics. Group 2 (n = 63) received US-guided bilateral TAP blocks and RSBs using 20 mL 0.25% ropivacaine in each block. Postoperative pain scores, the dose of intraoperative remifentanil, 24 h consumption of oxycodone, adverse events such as postoperative dizziness, nausea and vomiting, and the length of postoperative hospital stay were recorded. Results:In the postanesthesia care unit, patients in group 2 had significantly lower pain visual analog scale (VAS) scores at rest than those in group 1 (P < 0.001). The VAS scores both at rest and during movement were significantly lower in group 2 than in group 1 at 2, 4 and 6 h postoperatively (all P < 0.001). There was no difference in VAS scores between the two groups at rest 24 h postoperatively (P = 0.477). However, the VAS score during movement at 24 h in group 2 was significantly lower than that in group 1 (P < 0.001). No significant differences in the incidence of adverse events or the dose of intraoperative remifentanil were observed between the two groups (all P > 0.05). Patients in group 2 had a significantly lower 24 h consumption of oxycodone than patients in group 1 (P < 0.001). The mean length of postoperative hospital stay of group 2 was shorter than that of group 1 (P = 0.032). Conclusion:US-guided bilateral TAP blocks combined with RSBs provide effective postoperative analgesia for laparoscopic hepatectomy, and they could shorten the postoperative hospital stay without increasing the incidence of adverse events from opioids.

journal_name

Ther Clin Risk Manag

authors

Lu X,Yu P,Ou C,Wang J,Zhou Z,Lai R

doi

10.2147/TCRM.S267735

subject

Has Abstract

pub_date

2020-09-18 00:00:00

pages

881-888

eissn

1176-6336

issn

1178-203X

pii

267735

journal_volume

16

pub_type

杂志文章
  • Evaluation of external pressure to the sacral region in the lithotomy position using the noninvasive pressure distribution measurement system.

    abstract:BACKGROUND:Pressure ulcers (PUs) in the sacral region can be a complication of surgical procedures performed in the lithotomy position. Previous reports have noted a difference between men and women in PU development related to the supine position, and body weight and body mass index (BMI) have been also described as k...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S122489

    authors: Mizuno J,Takahashi T

    更新日期:2017-02-17 00:00:00

  • Axicabtagene ciloleucel (KTE-C19), an anti-CD19 CAR T therapy for the treatment of relapsed/refractory aggressive B-cell non-Hodgkin's lymphoma.

    abstract::Adoptive T-cell immunotherapy is a rapidly growing field and is shifting the paradigm of clinical cancer treatment. Axicabtagene ciloleucel (axi-cel) is an anti-CD19 chimeric antigen receptor T-cell therapy that was initially developed at the National Cancer Institute and has recently been commercially approved by the...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S145039

    authors: Jain MD,Bachmeier CA,Phuoc VH,Chavez JC

    更新日期:2018-05-31 00:00:00

  • Treatment of premenstrual dysphoric disorder (PMDD) with a novel formulation of drospirenone and ethinyl estradiol.

    abstract::Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS). Pharmacologic options studied for treating severe PMS and PMDD may include selective serotonin reuptake inhibitors, anxiolytic agents, gonadotropin-releasing hormone agonists and the diuretic spironolactone. However, the use of com...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:

    authors: De Berardis D,Serroni N,Salerno RM,Ferro FM

    更新日期:2007-08-01 00:00:00

  • Therapeutic Approaches to Gastric Hepatoid Adenocarcinoma: Current Perspectives.

    abstract::Hepatoid adenocarcinoma of the stomach (HAS) is a rare subgroup of gastric cancer (GC). Morphologically, this tumor exhibits both adenocarcinomatous and hepatocellular differentiation, and most tumors show immunohistochemical staining for alpha-fetoprotein (AFP) or elevated AFP serum levels. The diagnosis of HAS is fr...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S204303

    authors: Søreide JA

    更新日期:2019-12-23 00:00:00

  • Total hip arthroplasty following arthrodesis: a single-center experience of 17 patients.

    abstract:Purpose:We aimed to present our experience with total hip arthroplasty in patients with previous hip arthrodesis. Patients and methods:This was a retrospective study, in which clinical and radiological outcomes of total hip arthroplasty performed in 17 patients (mean age 54.2±8.5 years; age range 33-68 years; female t...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S163569

    authors: Çalbıyık M

    更新日期:2018-04-11 00:00:00

  • Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors.

    abstract::Procarbazine HCl is a 'nonclassical' oral alkylating anticancer agent that was first synthesized in the late 1950s. It has been used in the treatment of many cancers, but its main use is in the treatment of Hodgkin's lymphoma and brain tumors and, to a lesser extent, Non-Hodgkin's lymphoma and primary central nervous ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2007.3.2.213

    authors: Armand JP,Ribrag V,Harrousseau JL,Abrey L

    更新日期:2007-06-01 00:00:00

  • Therapeutic implications of Epstein-Barr virus infection for the treatment of nasopharyngeal carcinoma.

    abstract::Nasopharyngeal carcinoma (NPC) is highly endemic in certain regions including the People's Republic of China and Southeast Asia. Its etiology is unique and multifactorial, involving genetic background, epigenetic, and environment factors, including Epstein-Barr virus (EBV) infection. The presence of EBV in all tumor c...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S47434

    authors: Hutajulu SH,Kurnianda J,Tan IB,Middeldorp JM

    更新日期:2014-09-05 00:00:00

  • The Double Burden of the COVID-19 Pandemic and Polypharmacy on Geriatric Population - Public Health Implications.

    abstract::COVID-19 pandemic is inducing acute respiratory distress syndrome, multi-organ failure, and eventual death. Respiratory failure is the leading cause of mortality in the elderly population with pre-existing medical conditions. This group is particularly vulnerable to infections due to a declined immune system, comorbid...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S272908

    authors: Rahman S,Singh K,Dhingra S,Charan J,Sharma P,Islam S,Jahan D,Iskandar K,Samad N,Haque M

    更新日期:2020-10-20 00:00:00

  • Effectiveness and prescription pattern of lipid-lowering therapy and its associated factors among patients with type 2 diabetes mellitus in Malaysian primary care settings.

    abstract:Background:Cardiovascular diseases (CVDs) are the main complication leading to morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). There is a large amount of evidence to support the use of lipid-lowering therapy (LLT) for the prevention of CVD. This study aimed to assess the effectiveness and p...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S182716

    authors: Elnaem MH,Mohamed MHN,Huri HZ,Shah ASM

    更新日期:2019-01-18 00:00:00

  • Radiofrequency ablation versus resection for Barcelona clinic liver cancer very early/early stage hepatocellular carcinoma: a systematic review.

    abstract:AIM:To compare the long-term survival outcomes of radiofrequency ablation and liver resection for single very early/early stage hepatocellular carcinoma (HCC). METHODS:The Cochrane Library (Issue 3, 2015), Embase (1974 to March 15, 2015), PubMed (1950 to March 15, 2015), Web of Science (1900 to March 15, 2015), and Ch...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S96760

    authors: He ZX,Xiang P,Gong JP,Cheng NS,Zhang W

    更新日期:2016-02-23 00:00:00

  • Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy.

    abstract::Paclitaxel is an anticancer agent effective for the treatment of breast, ovarian, lung, and head and neck cancer. Because of water insolubility, paclitaxel is formulated with the micelle-forming vehicle Cremophor EL to enhance drug solubility. However, the addition of Cremophor EL results in hypersensitivity reactions...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.1.2.107.62910

    authors: Scripture CD,Figg WD,Sparreboom A

    更新日期:2005-06-01 00:00:00

  • Survival Rates of Endodontically Treated Teeth After Placement of Definitive Coronal Restoration: 8-Year Retrospective Study.

    abstract:Introduction:Preservation of endodontically treated teeth (ETT) depends upon several patient-related and operator-related factors. The objectives of this study were to assess the effects of different types of coronal restoration and delayed placement on ETT survival. Methods:Data on dates of root canal treatment (RCT)...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S223233

    authors: Sadaf D

    更新日期:2020-02-21 00:00:00

  • Clinical differences between H3N2 and H1N1 influenza 2012 and lower respiratory tract infection found using a statistical classification approach.

    abstract:BACKGROUND:Influenza A H1N1 and H3N2 are two influenza waves that have been identified in past years. METHODS:Data from 77 inpatients from three tertiary hospitals were included and statistical analysis was performed in three different clusters. RESULTS:Thirty-four patients (44.2%) had respiratory distress upon admis...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S57429

    authors: Petridis D,Zarogoulidis P,Kallianos A,Kioumis I,Trakada G,Spyratos D,Papaiwannou A,Porpodis K,Huang H,Rapti A,Hohenforst-Schmidt W,Zarogoulidis K

    更新日期:2014-02-07 00:00:00

  • Effects of short-term combined treatment with alendronate and elcatonin on bone mineral density and bone turnover in postmenopausal women with osteoporosis.

    abstract::The antiresorptive drug elcatonin (ECT) is known to relieve pain in postmenopausal women with osteoporosis. A prospective open-labeled trial was conducted to compare the effects of short-term combined treatment with alendronate (ALN) and ECT on bone mineral density (BMD) and bone turnover with those of single treatmen...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s5982

    authors: Iwamoto J,Uzawa M,Sato Y,Takeda T,Matsumoto H

    更新日期:2009-06-01 00:00:00

  • Cancer treatment-induced mucositis pain: strategies for assessment and management.

    abstract::Mucositis pain is a major clinical problem associated with cancer treatment. Mucosal tissue injury is a dose-limiting side effect and also limits nutritional intake and oral function, resulting in weight loss and nutritional deficits for many patients. The pathophysiology of mucositis is thought to be a complex array ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.2006.2.3.251

    authors: Harris DJ

    更新日期:2006-09-01 00:00:00

  • Angioid streaks, clinical course, complications, and current therapeutic management.

    abstract::Angioid streaks are visible irregular crack-like dehiscences in Bruch's membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget's disease, sickle-cell anemia, acromegaly, Ehlers-Danlos syndrome, and di...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:

    authors: Georgalas I,Papaconstantinou D,Koutsandrea C,Kalantzis G,Karagiannis D,Georgopoulos G,Ladas I

    更新日期:2009-02-01 00:00:00

  • Udenafil for the treatment of erectile dysfunction.

    abstract::Erectile dysfunction (ED) is often perceived by both patients and sexual partners as a serious problem that can jeopardize quality of life, psychosocial or emotional well-being, and the partnership in the long term. Since their introduction, oral phosphodiesterase type 5 inhibitors (PDE5Is) have been found to be highl...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S39727

    authors: Cho MC,Paick JS

    更新日期:2014-05-14 00:00:00

  • Management and outcomes of hyperparathyroidism: a case series from a single institution over two decades.

    abstract:Background:Hyperparathyroidism is a frequent endocrine disorder with variable clinical manifestations and outcomes. We aimed to evaluate clinical presentations, management and outcomes of hyperparathyroidism. Methods:A retrospective study was conducted to include all patients presented with hyperparathyroidism between...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S160896

    authors: Al-Thani H,El-Matbouly M,Al-Sulaiti M,Asim M,Majzoub A,Tabeb A,El-Menyar A

    更新日期:2018-07-31 00:00:00

  • The use of the C-MAC videolaryngoscope for awake intubation in patients with a predicted extremely difficult airway: case series.

    abstract::The C-MAC videolaryngoscope was evaluated for intubation in patients with predicted extremely difficult airway. The presented cases are patients with neoplasm tumors in larynx. In all cases, awake intubation using C-MAC videolaryngoscope was performed in patients breathing spontaneously, under local anaesthesia, with ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S150536

    authors: Gaszyński T

    更新日期:2018-03-14 00:00:00

  • New approaches in the treatment of HIV/AIDS - focus on maraviroc and other CCR5 antagonists.

    abstract::Treatment of HIV-1 infection has produced dramatic success for many patients. Nevertheless, viral resistance continues to limit the efficacy of currently available agents in many patients. The CCR5 antagonists are a new class of antiretroviral agents that target a necessary coreceptor for viral entry of many strains o...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s1997

    authors: Schlecht HP,Schellhorn S,Dezube BJ,Jacobson JM

    更新日期:2008-04-01 00:00:00

  • Combined therapy in the treatment of mixed etiology leg ulcer - case report.

    abstract::The most frequent causes of leg ulcers are chronic venous disease (CVD) related mainly to venous hypertension and peripheral arterial disease (PAD) related to disseminated atheromatous lesions in lower limb arteries. In 15%-21% of patients, ulcers of mixed venous-arterial etiology occur, which are usually more resista...

    journal_title:Therapeutics and clinical risk management

    pub_type:

    doi:10.2147/TCRM.S176321

    authors: Pasek J,Cieślar G,Sieroń A

    更新日期:2018-10-08 00:00:00

  • Early ischemic CT changes before thrombolysis: The influence of age and diabetes mellitus.

    abstract:OBJECTIVES:The significance of early ischemic changes (EIC) on computed tomography (CT) within 3 hours after stroke onset remains controversial. The semi-quantitative Alberta Stroke Program Early CT Score (ASPECTS) is found to have prognostic value in early stroke. This study assesses factors associated with the presen...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/tcrm.s2812

    authors: Thomassen L,Waje-Andreassen U,Naess H

    更新日期:2008-08-01 00:00:00

  • Retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys.

    abstract::Background: To report our experience with retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy in adult patients with duplex kidneys. Methods: We retrospectively reviewed the medical records of 7 patients who underwent retroperitoneal robot-assisted laparoscopic upper pole heminephrectomy at our inst...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S202454

    authors: Qin J,Wang P,Jing T,Kong D,Ye S,Xia D,Wang S

    更新日期:2019-06-11 00:00:00

  • The short-term effects of intravitreal aflibercept injections and dexamethasone implant on ocular hemodynamics in retinal vein occlusions.

    abstract:Purpose:To determine the early effects of intravitreal anti-VEGF and dexamethasone application on blood flow velocities in patients with retinal vein occlusions. Methods:The ophthalmic (OA) and the central retinal arteries (CRAs) of the affected and unaffected eyes of 21 patients with central retinal vein occlusion (C...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S200658

    authors: Ciloglu E,Yıldırım Celikdemir A

    更新日期:2019-07-04 00:00:00

  • Effect of patient-specific factors on weekly warfarin dose.

    abstract:OBJECTIVE:To determine the influence of various patient-specific factors, use of concomitant medications, and weekly vitamin K intake on total weekly warfarin maintenance dose (TWD). METHODS:Information collected, via retrospective chart review, included TWD, general demographics, vitamin K consumption, target INR ran...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:

    authors: Whitley HP,Fermo JD,Chumney EC,Brzezinski WA

    更新日期:2007-06-01 00:00:00

  • Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Predicting Death Risk in Patients with Severe Hand, Foot and Mouth Disease.

    abstract:Introduction:Severe hand, foot, and mouth disease (HFMD) may lead to serious complications, which cause child mortality during outbreaks. The aim of this study was to determine whether neutrophil-to-lymphocyte ratio (NLR) can predict death risk in severe HFMD. Methods:Medical records for 664 severe HFMD patients were ...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S268130

    authors: Li Y,Wang M,Wang W,Feng D,Deng H,Zhang Y,Dang S,Zhai S

    更新日期:2020-10-23 00:00:00

  • Recovery of a 10-year-old girl from methicillin-resistant Staphylococcus aureus sepsis in response to low-dose ceftaroline treatment.

    abstract::A 9-year-old girl was severely injured in a car accident in Afghanistan, in which both her lower legs were badly damaged. She was treated at the Hospital of Ingolstadt (Klinikum Ingolstadt) after she had undergone initial surgery at an Indian hospital. Various bacterial species were isolated from multiple wounds, and ...

    journal_title:Therapeutics and clinical risk management

    pub_type:

    doi:10.2147/TCRM.S99987

    authors: Borgmann S,Rieß B,von Wernitz-Keibel T,Bühler M,Layer F,Strommenger B

    更新日期:2016-05-11 00:00:00

  • Outcomes of Adding Induction Chemotherapy to Concurrent Chemotherapy for Nasopharyngeal Carcinoma Patients with Moderate-Risk in the Intensity-Modulated Radiotherapy Era.

    abstract:Background:The aim of this study was to evaluate the efficacy of induction chemotherapy (IC) in nasopharyngeal carcinoma (NPC) patients with moderate-risk treated with intensity-modulated radiotherapy (IMRT). Methods:We retrospectively assessed 506 patients with T1-2N1M0 or T3-4N0-1M0 NPC (according to the 2010 UICC/A...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S241216

    authors: Su Z,Zou GR,Tang J,Li XY,Xie FY

    更新日期:2020-03-26 00:00:00

  • Safety and efficacy of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP): a systematic review and meta-analysis.

    abstract:Objective:Retrospective studies and a meta-analysis were performed to evaluate the safety and effectiveness of the perioperative administration of recombinant human brain natriuretic peptide (rhBNP) during cardiac surgery under extracorporeal circulation. Methods:Computerized literature searches were performed in Medl...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章

    doi:10.2147/TCRM.S143247

    authors: Hua P,Liu J,Tao J,Lin X,Zou R,Zhang D,Yang S

    更新日期:2018-02-20 00:00:00

  • Secukinumab for ankylosing spondylitis and psoriatic arthritis.

    abstract::The treatment of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) positively changed since the introduction of anti-TNFα drugs. These treatments were shown to reduce the symptoms and signs of the diseases and improve the quality of life. However, a variable percentage of patients do not respond to anti-TNFα o...

    journal_title:Therapeutics and clinical risk management

    pub_type: 杂志文章,评审

    doi:10.2147/TCRM.S100091

    authors: Lubrano E,Perrotta FM

    更新日期:2016-10-21 00:00:00