Human cellular immune responses against human papillomaviruses in cervical neoplasia.

Abstract:

:Human papillomaviruses (HPVs) are ubiquitous DNA viruses that infect cutaneous and mucosal epithelia. A subset of HPVs infects the female genital tract, to induce cervical lesions that can progress to malignancy in some women. DNA from HPVs can be found in >94% of cervical carcinomas (CaCx) worldwide; this strong association suggests that it might be possible to develop either prophylaxis or therapies for cervical neoplasia, based on the manipulation of human immune responses against HPVs. This review examines the current research into human immune responses against HPVs in CaCx and the potential impact of this research on human health.

journal_name

Expert Rev Mol Med

authors

Man S

doi

10.1017/S1462399498000210

keywords:

subject

Has Abstract

pub_date

1998-07-03 00:00:00

pages

1-19

issn

1462-3994

pii

S1462399498000210

journal_volume

1998

pub_type

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