Role of molecular cell biology in understanding disease.

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE:To evaluate the cost effectiveness of acupuncture in the management of chronic headache. DESIGN:Cost effectiveness analysis of a randomised controlled trial. SETTING:General practices in England and Wales. PARTICIPANTS:401 patients with chronic headache, predominantly migraine. Interventions Patients were ...

journal_title：BMJ (Clinical research ed.)

authors： Wonderling D,Vickers AJ,Grieve R,McCarney R

更新日期：2004-03-27 00:00:00

abstract：OBJECTIVE:To investigate differences between hospitals in clinical management of patients admitted with fractured hip and to relate these to mortality at 90 days. DESIGN:A prospective audit of process and outcome of care based on interviews with patients, abstraction from records with standard proforma, and follow up ...

journal_title：BMJ (Clinical research ed.)

authors： Todd CJ,Freeman CJ,Camilleri-Ferrante C,Palmer CR,Hyder A,Laxton CE,Parker MJ,Payne BV,Rushton N

更新日期：1995-04-08 00:00:00

abstract：OBJECTIVE:To determine whether total hip arthroplasty is associated with lower reoperation rates, mortality, and complications, and better function and quality of life than hemiarthroplasty for displaced fractures of the femoral neck in older patients. DESIGN:Systematic review and meta-analysis of randomised trials, q...

journal_title：BMJ (Clinical research ed.)

authors： Hopley C,Stengel D,Ekkernkamp A,Wich M

更新日期：2010-06-11 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. DESIGN:Randomised controlled equivalence trial. SETTING:Community, with home visits. PARTICIPANTS:214 young people aged 4 to 18 years and 39 adults with active head louse infestation. INTERVENTIONS:Two app...

journal_title：BMJ (Clinical research ed.)

authors： Burgess IF,Brown CM,Lee PN

更新日期：2005-06-18 00:00:00

abstract：OBJECTIVE:To determine whether a booklet given to patients being discharged from hospital giving details of their admission and treatment increased their knowledge and recall when reviewed in outpatient clinics. DESIGN:Patients alternately allocated to receive a booklet or to serve as controls. Assessment by a questio...

journal_title：BMJ (Clinical research ed.)

authors： Sandler DA,Mitchell JR,Fellows A,Garner ST

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:To examine the association between accidental dural puncture and long term headache and related symptoms. DESIGN:Postal questionnaire survey to elucidate new symptoms occurring after childbirth, and linking of these to data in obstetric and anaesthetic case notes. Women were surveyed between 13 months and ni...

journal_title：BMJ (Clinical research ed.)

authors： MacArthur C,Lewis M,Knox EG

更新日期：1993-04-03 00:00:00

abstract：:Managed care has entered the lexicon of healthcare reform, but confusion and ignorance surround its meaning and purpose. It seeks to cut the costs of health care while maintaining its quality, but the evidence that it is able to achieve these aims is mixed. As well as raising awareness and understanding of the issues ...

journal_title：BMJ (Clinical research ed.)

authors： Fairfield G,Hunter DJ,Mechanic D,Rosleff F

更新日期：1997-06-21 00:00:00

abstract：OBJECTIVE:To estimate the risk of acute hepatotoxicity associated with nimesulide compared with other non-steroidal anti-inflammatory drugs. DESIGN:Retrospective cohort and nested case-control study. SETTING:Umbria region, Italy. PARTICIPANTS:400 000 current, recent, and past users (almost 2 million prescriptions) o...

journal_title：BMJ (Clinical research ed.)

authors： Traversa G,Bianchi C,Da Cas R,Abraha I,Menniti-Ippolito F,Venegoni M

更新日期：2003-07-05 00:00:00

abstract：OBJECTIVES:To determine whether an aid to the diagnosis of pigmented skin lesions reduces the ratio of benign lesions to melanomas excised in general practice. DESIGN:Controlled trial randomised by practice. SETTING:General practices in Perth, Western Australia. PARTICIPANTS:468 general practitioners in 223 practice...

journal_title：BMJ (Clinical research ed.)

authors： English DR,Burton RC,del Mar CB,Donovan RJ,Ireland PD,Emery G

更新日期：2003-08-16 00:00:00

abstract：OBJECTIVE:To determine the appropriateness of referrals from general practice to hospital outpatient departments. DESIGN:Prospective audit of referrals from a group practice over one year. SETTING:Six handed practice in a southern coastal town. SUBJECTS:All patients referred during the study period for whom a copy o...

journal_title：BMJ (Clinical research ed.)

authors： Emmanuel J,Walter N

更新日期：1989-09-16 00:00:00

abstract：OBJECTIVE:To estimate changes in the risk of autism and assess the relation of autism to the mumps, measles, and rubella (MMR) vaccine. DESIGN:Time trend analysis of data from the UK general practice research database (GPRD). SETTING:General practices in the United Kingdom. SUBJECTS:Children aged 12 years or younger...

journal_title：BMJ (Clinical research ed.)

authors： Kaye JA,del Mar Melero-Montes M,Jick H

更新日期：2001-02-24 00:00:00

abstract：OBJECTIVE:To investigate the effect of watching different types of video on energy expenditure. DESIGN:Randomised study assessing a "pleasant," an "amusing," an "exciting," and no video film clips. SUBJECTS:12 volunteers who did not know the purpose of the study. MAIN OUTCOME MEASURES:Changes in energy expenditure, ...

journal_title：BMJ (Clinical research ed.)

authors： Cooper BG,Matthews JN,Alberti KG

更新日期：1995-12-23 00:00:00

abstract：OBJECTIVE:To compare health behaviours during pregnancy (smoking and alcohol consumption) and after birth (initiation and duration of breast feeding) between British/Irish white mothers and mothers from ethnic minority groups; and, in mothers from ethnic minority groups, to examine whether indicators of acculturation (...

journal_title：BMJ (Clinical research ed.)

authors： Hawkins SS,Lamb K,Cole TJ,Law C,Millennium Cohort Study Child Health Group.

更新日期：2008-05-10 00:00:00

abstract：OBJECTIVE:To examine changes in representation of women among first authors of original research published in high impact general medical journals from 1994 to 2014 and investigate differences between journals. DESIGN:Observational study. STUDY SAMPLE:All original research articles published in Annals of Internal Med...

journal_title：BMJ (Clinical research ed.)

authors： Filardo G,da Graca B,Sass DM,Pollock BD,Smith EB,Martinez MA

更新日期：2016-03-02 00:00:00

abstract：:Objective To examine off-label indications for antidepressants in primary care and determine the level of scientific support for off-label prescribing.Design Descriptive study of antidepressant prescriptions written by primary care physicians using an indication based electronic prescribing system.Setting Primary care...

journal_title：BMJ (Clinical research ed.)

authors： Wong J,Motulsky A,Abrahamowicz M,Eguale T,Buckeridge DL,Tamblyn R

更新日期：2017-02-21 00:00:00

abstract：:Organs for donation are in short supply in the United Kingdom, resulting in allegations that relatives of potential donors are not being asked for consent. Legislation on "required request" has been proposed to overcome this. The incidence, causes, complications, and patterns of organ donation in brain stem dead patie...

journal_title：BMJ (Clinical research ed.)

authors： Bodenham A,Berridge JC,Park GR

更新日期：1989-10-21 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：:The meaning of the GP contract has changed since the last major upheaval in the mid-1960s. The government has always dealt with general practitioners as independent contractors, but the way in which it treated them in 1990 was entirely different from the way in which they were treated in 1966. In 1966, the profession'...

journal_title：BMJ (Clinical research ed.)

authors： Lewis J

更新日期：1997-03-22 00:00:00

abstract：OBJECTIVES: To determine whether late mortality after sepsis is driven predominantly by pre-existing comorbid disease or is the result of sepsis itself. DEIGN: Observational cohort study. SETTING: US Health and Retirement Study. PARTICIPANTS: 960 patients aged ≥65 (1998-2010) with fee-for-service Medicare coverage w...

journal_title：BMJ (Clinical research ed.)

authors： Prescott HC,Osterholzer JJ,Langa KM,Angus DC,Iwashyna TJ

更新日期：2016-05-17 00:00:00

abstract：OBJECTIVE:To assess the efficacy of arthroscopic subacromial decompression (ASD) by comparing it with diagnostic arthroscopy, a placebo surgical intervention, and with a non-operative alternative, exercise therapy, in a more pragmatic setting. DESIGN:Multicentre, three group, randomised, double blind, sham controlled ...

journal_title：BMJ (Clinical research ed.)

authors： Paavola M,Malmivaara A,Taimela S,Kanto K,Inkinen J,Kalske J,Sinisaari I,Savolainen V,Ranstam J,Järvinen TLN,Finnish Subacromial Impingement Arthroscopy Controlled Trial (FIMPACT) Investigators.

更新日期：2018-07-19 00:00:00

abstract：OBJECTIVE:To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the intervention or outcome. DESIGN:Combined analysis of data from three meta-epidemiological studies based on collections of meta-an...

journal_title：BMJ (Clinical research ed.)

authors： Wood L,Egger M,Gluud LL,Schulz KF,Jüni P,Altman DG,Gluud C,Martin RM,Wood AJ,Sterne JA

更新日期：2008-03-15 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVE:To determine the effects on independence in older people needing rehabilitation in a locality based community hospital compared with care on a ward for elderly people in a district general hospital. DESIGN:Randomised controlled trial. SETTING:Care in a community hospital and district general hospital in Bra...

journal_title：BMJ (Clinical research ed.)

authors： Green J,Young J,Forster A,Mallinder K,Bogle S,Lowson K,Small N

更新日期：2005-08-06 00:00:00

abstract：:For the past 18 years there has been a proliferation of European committees, boards, associations, colleges, and working groups set up to promote the harmonisation of specialist training in Europe. It has been taken as read that this objective is desirable. The fact that these bodies have achieved remarkably little is...

journal_title：BMJ (Clinical research ed.)

authors： Brearley S

更新日期：1995-07-29 00:00:00

abstract：PROBLEM:To reduce hospital inpatient mortality and thus increase public confidence in the quality of patient care in an urban acute hospital trust after adverse media coverage. DESIGN:Eight care bundles of treatments known to be effective in reducing in-hospital mortality were used in the intervention year; adjusted m...

journal_title：BMJ (Clinical research ed.)

authors： Robb E,Jarman B,Suntharalingam G,Higgens C,Tennant R,Elcock K

更新日期：2010-03-31 00:00:00

abstract：OBJECTIVE:To assess the cost-effectiveness of low dose statins for primary prevention of vascular disease, incorporating current prices, non-adherence (reduced clinical efficacy while maintaining healthcare costs), and the results of the recently published JUPITER trial. DESIGN:Cost-effectiveness analysis using a Mark...

journal_title：BMJ (Clinical research ed.)

authors： Greving JP,Visseren FL,de Wit GA,Algra A

更新日期：2011-03-30 00:00:00

abstract：OBJECTIVE:To determine whether poor reporting of methods in randomised controlled trials reflects on poor methods. DESIGN:Observational study. SETTING:Reports of randomised controlled trials conducted by the Radiation Therapy Oncology Group since its establishment in 1968. PARTICIPANTS:The Radiation Therapy Oncology...

journal_title：BMJ (Clinical research ed.)

authors： Soares HP,Daniels S,Kumar A,Clarke M,Scott C,Swann S,Djulbegovic B,Radiation Therapy Oncology Group.

更新日期：2004-01-03 00:00:00

abstract：OBJECTIVE:To determine the effect of home blood pressure monitoring on blood pressure levels and proportion of people with essential hypertension achieving targets. DESIGN:Meta-analysis of 18 randomised controlled trials. PARTICIPANTS:1359 people with essential hypertension allocated to home blood pressure monitoring...

journal_title：BMJ (Clinical research ed.)

authors： Cappuccio FP,Kerry SM,Forbes L,Donald A

更新日期：2004-07-17 00:00:00