Primary care--opportunities and threats. The changing meaning of the GP contract.

abstract：:A total of 22,552 workers employed by the Atomic Weapons Establishment between 1951 and 1982 were followed up for an average of 18.6 years. Of the 3115 who died, 865 (28%) died of cancer. Mortality was 23% lower than the national average for all causes of death and 18% lower for cancer. These low rates were consistent...

journal_title：BMJ (Clinical research ed.)

authors： Beral V,Fraser P,Carpenter L,Booth M,Brown A,Rose G

更新日期：1988-09-24 00:00:00

abstract：OBJECTIVE:To determine the efficacy of high dose folic acid supplementation for prevention of pre-eclampsia in women with at least one risk factor: pre-existing hypertension, prepregnancy diabetes (type 1 or 2), twin pregnancy, pre-eclampsia in a previous pregnancy, or body mass index ≥35. DESIGN:Randomised, phase III...

journal_title：BMJ (Clinical research ed.)

authors： Wen SW,White RR,Rybak N,Gaudet LM,Robson S,Hague W,Simms-Stewart D,Carroli G,Smith G,Fraser WD,Wells G,Davidge ST,Kingdom J,Coyle D,Fergusson D,Corsi DJ,Champagne J,Sabri E,Ramsay T,Mol BWJ,Oudijk MA,Walker MC,

更新日期：2018-09-12 00:00:00

abstract：OBJECTIVE:Rapid diagnostic tests for malaria seem cost effective in standard analyses, but these do not take account of clinicians' response to test results. This study tested the impact of clinicians' response to rapid diagnostic test or microscopy results on the costs and benefits of testing at different levels of ma...

journal_title：BMJ (Clinical research ed.)

authors： Lubell Y,Reyburn H,Mbakilwa H,Mwangi R,Chonya S,Whitty CJ,Mills A

更新日期：2008-01-26 00:00:00

abstract：OBJECTIVES:To audit services for prenatal diagnosis for haemoglobin disorders in the United Kingdom. DESIGN:Comparison of the annual number of cases recorded in a United Kingdom register of prenatal diagnoses for haemoglobin disorders, with the annual number of pregnancies at risk of these disorders, by ethnic group a...

journal_title：BMJ (Clinical research ed.)

authors： Modell B,Petrou M,Layton M,Varnavides L,Slater C,Ward RH,Rodeck C,Nicolaides K,Gibbons S,Fitches A,Old J

更新日期：1997-09-27 00:00:00

abstract：OBJECTIVE:To examine the absolute risks or benefits on cancer associated with oral contraception, using incident data. DESIGN:Inception cohort study. SETTING:Royal College of General Practitioners' oral contraception study. PARTICIPANTS:Directly standardised data from the Royal College of General Practitioners' oral...

journal_title：BMJ (Clinical research ed.)

authors： Hannaford PC,Selvaraj S,Elliott AM,Angus V,Iversen L,Lee AJ

更新日期：2007-09-29 00:00:00

abstract：OBJECTIVE:To compare the clinical effectiveness of local corticosteroid injection, standard non-steroidal anti-inflammatory drugs, and simple analgesics for the early treatment of lateral epicondylitis in primary care. DESIGN:Multicentre pragmatic randomised controlled trial. SETTING:23 general practices in North Sta...

journal_title：BMJ (Clinical research ed.)

authors： Hay EM,Paterson SM,Lewis M,Hosie G,Croft P

更新日期：1999-10-09 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism. DESIGN:Double blind randomised placebo controlled trial. SETTING:35 centres in eight countries. PARTICIPANTS:849 medical patients aged 60 or more admi...

journal_title：BMJ (Clinical research ed.)

authors： Cohen AT,Davidson BL,Gallus AS,Lassen MR,Prins MH,Tomkowski W,Turpie AG,Egberts JF,Lensing AW,ARTEMIS Investigators.

更新日期：2006-02-11 00:00:00

abstract：OBJECTIVES:To investigate whether routinely collected data from hospital episode statistics could be used to identify the gynaecologist Rodney Ledward, who was suspended in 1966 and was the subject of the Ritchie inquiry into quality and practice within the NHS. DESIGN:A mixed scanning approach was used to identify se...

journal_title：BMJ (Clinical research ed.)

authors： Harley M,Mohammed MA,Hussain S,Yates J,Almasri A

更新日期：2005-04-23 00:00:00

abstract：OBJECTIVES:To clarify the type of fetal growth impairment associated with increased blood pressure in adult life, and to establish whether this association is influenced by obesity and is mediated through impairment of insulin action. DESIGN:Cross sectional survey with retrospective ascertainment of size at birth from...

journal_title：BMJ (Clinical research ed.)

authors： Leon DA,Koupilova I,Lithell HO,Berglund L,Mohsen R,Vagero D,Lithell UB,McKeigue PM

更新日期：1996-02-17 00:00:00

abstract：OBJECTIVES:To gain insight into people's thoughts on stroke and to inform the development of educational strategies in the community. DESIGN:Focus group discussions: two groups of people who had a stroke and their carers, and two groups of members of the general public. SETTING:New South Wales, Australia. PARTICIPAN...

journal_title：BMJ (Clinical research ed.)

authors： Yoon SS,Byles J

更新日期：2002-05-04 00:00:00

abstract：OBJECTIVE:To evaluate the association between use of hormone replacement therapy and the risk of idiopathic venous thromboembolism. DESIGN:Population based case-control study. SETTING:Population enrolled in the General Practice Research Database, United Kingdom. SUBJECTS:A cohort of 347,253 women aged 50 to 79 witho...

journal_title：BMJ (Clinical research ed.)

authors： Pérez Gutthann S,García Rodríguez LA,Castellsague J,Duque Oliart A

更新日期：1997-03-15 00:00:00

abstract：OBJECTIVES:To determine the prevalence of drug and alcohol use among newly remanded prisoners, assess the effectiveness of prison reception screening, and examine the clinical management of substance misusers among remand prisoners. DESIGN:A consecutive case study of remand prisoners screened at reception for substanc...

journal_title：BMJ (Clinical research ed.)

authors： Mason D,Birmingham L,Grubin D

更新日期：1997-07-05 00:00:00

abstract：OBJECTIVE:To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. DESIGN:Meta-analysis of randomised trials of oral corticosteroids compared with placebo or a non-steroidal anti-inflammatory...

journal_title：BMJ (Clinical research ed.)

authors： Gøtzsche PC,Johansen HK

更新日期：1998-03-14 00:00:00

abstract：OBJECTIVE:To examine changes in immunisation performance in Grampian region after the introduction of the 1990 contract for general practitioners. DESIGN:Retrospective descriptive study using data held on the Grampian immunisation record system's computer. SETTING:All 95 general practices in Grampian region (313 gene...

journal_title：BMJ (Clinical research ed.)

authors： Ritchie LD,Bisset AF,Russell D,Leslie V,Thomson I

更新日期：1992-03-28 00:00:00

abstract：:Aside from email and the world wide web, there are several other systems for distributing information on the Internet. Telnet is a system that allows you to log on to a remote computer from anywhere on the Internet and affords access to many useful biomedical sites on the Internet. File transfer protocol (FTP) is a me...

journal_title：BMJ (Clinical research ed.)

authors： Pallen M

更新日期：1995-12-16 00:00:00

abstract：OBJECTIVE:To evaluate the association between migraine and cognitive decline among women. DESIGN:Prospective cohort study. SETTING:Women's Health Study, United States. PARTICIPANTS:6349 women aged 65 or older enrolled in the Women's Health Study who provided information about migraine status at baseline and particip...

journal_title：BMJ (Clinical research ed.)

authors： Rist PM,Kang JH,Buring JE,Glymour MM,Grodstein F,Kurth T

更新日期：2012-08-08 00:00:00

abstract：OBJECTIVES:To identify the need for reproductive health care among a community affected by conflict, and to ascertain the priority given by the community to reproductive health issues. DESIGN:Rapid appraisal. This comprised interviews with key informants, in-depth interviews, and group discussions. Secondary data were...

journal_title：BMJ (Clinical research ed.)

authors： Palmer CA

更新日期：1999-09-18 00:00:00

abstract：:To assess whether calcitonin is important in maintaining the integrity of bone the calcitonin gene of a young male patient with osteoporosis and no detectable plasma concentrations of calcitonin was studied. Genomic Southern blots with various restriction enzymes showed no large abnormalities in his calcitonin gene. G...

journal_title：BMJ (Clinical research ed.)

authors： Alevizaki M,Stevenson JC,Girgis SI,MacIntyre I,Legon S

更新日期：1989-05-06 00:00:00

abstract：OBJECTIVE:To discover if there is an association between respiratory tract infections and pericoronitis of erupting third molars in young adults. DESIGN:Data from male military conscripts' medical records were collected over five years and the incidence of respiratory tract infection before and after acute pericoronit...

journal_title：BMJ (Clinical research ed.)

authors： Meurman JH,Rajasuo A,Murtomaa H,Savolainen S

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of oral rehydration in children with moderate dehydration caused by gastroenteritis, and to compare the complications of oral and intravenous treatment. DESIGN:Randomised controlled trial. SETTING:Emergency department and infectious diseases ward in a large urban teaching hosp...

journal_title：BMJ (Clinical research ed.)

authors： Mackenzie A,Barnes G

更新日期：1991-08-17 00:00:00

abstract：:In the absence of any systematic evaluation of the changes it has made to the NHS, the government cites three "indicators of success." These are record numbers of patients treated, shorter waiting times for hospital treatment, and more children being immunised against the main childhood diseases. Closer inspection of ...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1995-04-22 00:00:00

abstract：OBJECTIVE:To investigate the association between tea drinking habits in Golestan province, northern Iran, and risk of oesophageal squamous cell carcinoma. DESIGN:Population based case-control study. In addition, patterns of tea drinking and temperature at which tea was drunk were measured among healthy participants in...

journal_title：BMJ (Clinical research ed.)

authors： Islami F,Pourshams A,Nasrollahzadeh D,Kamangar F,Fahimi S,Shakeri R,Abedi-Ardekani B,Merat S,Vahedi H,Semnani S,Abnet CC,Brennan P,Møller H,Saidi F,Dawsey SM,Malekzadeh R,Boffetta P

更新日期：2009-03-26 00:00:00

abstract：OBJECTIVE:To determine whether failure to adequately adjust for a reported 40% misclassification of use of in vitro fertilisation (IVF) as reported in a Swedish study could have led to a false finding that folic acid increases dizygotic twinning. DESIGN:Modelling with population based data. SETTING:Swedish vital reco...

journal_title：BMJ (Clinical research ed.)

authors： Berry RJ,Kihlberg R,Devine O

更新日期：2005-04-09 00:00:00

abstract：OBJECTIVES:To investigate the effectiveness of non-benzodiazepine hypnotics (Z drugs) and associated placebo responses in adults and to evaluate potential moderators of effectiveness in a dataset used to approve these drugs. DESIGN:Systematic review and meta-analysis. DATA SOURCE:US Food and Drug Administration (FDA)...

journal_title：BMJ (Clinical research ed.)

authors： Huedo-Medina TB,Kirsch I,Middlemass J,Klonizakis M,Siriwardena AN

更新日期：2012-12-17 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a monovalent rotavirus vaccine against severe rotavirus disease and to assess its impact on diarrhoea in children aged less than 2 years after national introduction in El Salvador, a low-middle income country in Central America. DESIGN:Matched case-control study. SETTING:Sev...

journal_title：BMJ (Clinical research ed.)

authors： de Palma O,Cruz L,Ramos H,de Baires A,Villatoro N,Pastor D,de Oliveira LH,Kerin T,Bowen M,Gentsch J,Esposito DH,Parashar U,Tate J,Patel M

更新日期：2010-06-15 00:00:00

abstract：OBJECTIVES:To determine the effectiveness of tai chi interventions compared with aerobic exercise, a current core standard treatment in patients with fibromyalgia, and to test whether the effectiveness of tai chi depends on its dosage or duration. DESIGN:Prospective, randomized, 52 week, single blind comparative effec...

journal_title：BMJ (Clinical research ed.)

authors： Wang C,Schmid CH,Fielding RA,Harvey WF,Reid KF,Price LL,Driban JB,Kalish R,Rones R,McAlindon T

更新日期：2018-03-21 00:00:00

abstract：:In the existing WHO guidelines, complementary feeding at 4-6 months is advocated. However, many nutrition specialists believe that these guidelines lead to complementary foods being offered from the age of 3 months, or even earlier, subsequently suggesting that the WHO should change its recommendations to about 6 mon...

journal_title：BMJ (Clinical research ed.)

authors： Yamey G

更新日期：2000-09-09 00:00:00

abstract：OBJECTIVES:To assess the compliance of Asian intensive care units and hospitals to the Surviving Sepsis Campaign's resuscitation and management bundles. Secondary objectives were to evaluate the impact of compliance on mortality and the organisational characteristics of hospitals that were associated with higher compli...

journal_title：BMJ (Clinical research ed.)

authors： Phua J,Koh Y,Du B,Tang YQ,Divatia JV,Tan CC,Gomersall CD,Faruq MO,Shrestha BR,Gia Binh N,Arabi YM,Salahuddin N,Wahyuprajitno B,Tu ML,Wahab AY,Hameed AA,Nishimura M,Procyshyn M,Chan YH,MOSAICS Study Group.

更新日期：2011-06-13 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVE:To test the effectiveness of an evidence based model for management of depression in primary care with support from quality improvement resources. DESIGN:Cluster randomised controlled trial. SETTING:Five healthcare organisations in the United States and 60 affiliated practices. PATIENTS:405 patients, aged ...

journal_title：BMJ (Clinical research ed.)

authors： Dietrich AJ,Oxman TE,Williams JW Jr,Schulberg HC,Bruce ML,Lee PW,Barry S,Raue PJ,Lefever JJ,Heo M,Rost K,Kroenke K,Gerrity M,Nutting PA

更新日期：2004-09-11 00:00:00