Research priorities in environmental health.

abstract：OBJECTIVE:To determine whether the more intensive screening and treatment for prostate cancer in the Seattle-Puget Sound area in 1987-90 led to lower mortality from prostate cancer than in Connecticut. DESIGN:Natural experiment comparing two fixed cohorts from 1987 to 1997. SETTING:Seattle-Puget Sound and Connecticut...

journal_title：BMJ (Clinical research ed.)

authors： Lu-Yao G,Albertsen PC,Stanford JL,Stukel TA,Walker-Corkery ES,Barry MJ

更新日期：2002-10-05 00:00:00

abstract：OBJECTIVE:To increase understanding of how the prison environment influences the mental health of prisoners and prison staff. DESIGN:Qualitative study with focus groups. SETTING:A local prison in southern England. PARTICIPANTS:Prisoners and prison staff. RESULTS:Prisoners reported that long periods of isolation wit...

journal_title：BMJ (Clinical research ed.)

authors： Nurse J,Woodcock P,Ormsby J

更新日期：2003-08-30 00:00:00

abstract：:Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these t...

journal_title：BMJ (Clinical research ed.)

authors： Kay-Stacey M,Attarian H

更新日期：2016-07-06 00:00:00

abstract：PROBLEM:To reduce hospital inpatient mortality and thus increase public confidence in the quality of patient care in an urban acute hospital trust after adverse media coverage. DESIGN:Eight care bundles of treatments known to be effective in reducing in-hospital mortality were used in the intervention year; adjusted m...

journal_title：BMJ (Clinical research ed.)

authors： Robb E,Jarman B,Suntharalingam G,Higgens C,Tennant R,Elcock K

更新日期：2010-03-31 00:00:00

abstract：OBJECTIVE:To determine if any excess of childhood leukaemia was associated with the large and increasing numbers of national military servicemen in 1949 and 1950, particularly in rural districts. This would be a further test of the hypothesis that childhood leukaemia can originate in an infection, the transmission of w...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,Hudson C

更新日期：1991-11-30 00:00:00

abstract：OBJECTIVE:To assess the effect of high dose inhaled corticosteroids on skin. DESIGN:Cross sectional study of patients receiving treatment for chest diseases. SETTING:Outpatient chest clinic in a teaching hospital. PATIENTS:68 Patients divided into four groups of similar age--namely, 15 receiving long term oral predn...

journal_title：BMJ (Clinical research ed.)

authors： Capewell S,Reynolds S,Shuttleworth D,Edwards C,Finlay AY

更新日期：1990-06-16 00:00:00

abstract：AIM:To compare perinatal morbidity and mortality for babies delivered in water with rates for babies delivered conventionally (not in water). DESIGN:Surveillance study (of all consultant paediatricians) and postal survey (of all NHS maternity units). SETTING:British Isles (surveillance study); England and Wales (post...

journal_title：BMJ (Clinical research ed.)

authors： Gilbert RE,Tookey PA

更新日期：1999-08-21 00:00:00

abstract：OBJECTIVES:To examine the reporting characteristics and methodological details of randomised trials indexed in PubMed in 2000 and 2006 and assess whether the quality of reporting has improved after publication of the Consolidated Standards of Reporting Trials (CONSORT) Statement in 2001. DESIGN:Comparison of two cross...

journal_title：BMJ (Clinical research ed.)

authors： Hopewell S,Dutton S,Yu LM,Chan AW,Altman DG

更新日期：2010-03-23 00:00:00

abstract：OBJECTIVES:To identify risk factors predisposing to the development of flucloxacillin associated jaundice. DESIGN:Case-control study. Medical records of cases and controls were reviewed and information recorded on standard data collection forms. SETTING:Alfred Hospital recruiting subjects from Melbourne, Sydney, and ...

journal_title：BMJ (Clinical research ed.)

authors： Fairley CK,McNeil JJ,Desmond P,Smallwood R,Young H,Forbes A,Purcell P,Boyd I

更新日期：1993-01-23 00:00:00

abstract：OBJECTIVE:To study the long term risk of cervical and other cancers after treatment for cervical intraepithelial neoplasia. DESIGN:Retrospective cohort study. SETTING:University Hospital, Helsinki, Finland. PARTICIPANTS:7564 women treated for cervical intraepithelial neoplasia during 1974 and 2001 and followed up th...

journal_title：BMJ (Clinical research ed.)

authors： Kalliala I,Anttila A,Pukkala E,Nieminen P

更新日期：2005-11-19 00:00:00

abstract：OBJECTIVES:To examine how insurance companies assess proposals for life assurance from applicants with raised cholesterol concentrations and to determine the excess mortality rating applied. DESIGN:Survey of 49 companies underwriting term life assurance. SETTING:United Kingdom. SUBJECTS:Four fictional men aged 30 se...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D

更新日期：1991-04-13 00:00:00

abstract：OBJECTIVE:To determine whether the variation in unadjusted rates of caesarean section derived from routine data in NHS trusts in England can be explained by maternal characteristics and clinical risk factors. DESIGN:A cross sectional analysis using routinely collected hospital episode statistics was performed. A multi...

journal_title：BMJ (Clinical research ed.)

authors： Bragg F,Cromwell DA,Edozien LC,Gurol-Urganci I,Mahmood TA,Templeton A,van der Meulen JH

更新日期：2010-10-06 00:00:00

abstract：OBJECTIVES:To assess timeliness of carotid endarterectomy services in the United Kingdom. DESIGN:Observational study with follow-up to March 2008. SETTING:UK hospitals performing carotid endarterectomy. PARTICIPANTS:UK surgeons undertaking carotid endarterectomy from December 2005 to December 2007. MAIN OUTCOME MEA...

journal_title：BMJ (Clinical research ed.)

authors： Halliday AW,Lees T,Kamugasha D,Grant R,Hoffman A,Rothwell PM,Potter JF,Horrocks M,Naylor R,Rudd AG,Carotid Endarterectomy Steering Group.,Clinical Effectiveness and Evaluation Unit, Royal College of Physicians.,Vascular Society o

更新日期：2009-06-04 00:00:00

abstract：OBJECTIVE:To determine prevalence of HIV infection and drug injecting behaviour among inmates of Glenochil Prison on a specified date a year after an outbreak of hepatitis B and HIV infection. DESIGN:Cross sectional: voluntary, anonymous HIV salivary antibody surveillance and linked self completion questionnaire on ri...

journal_title：BMJ (Clinical research ed.)

authors： Gore SM,Bird AG,Burns SM,Goldberg DJ,Ross AJ,Macgregor J

更新日期：1995-02-04 00:00:00

abstract：:Fetomaternal haemorrhage was studied after 68 consecutive fetal intravascular transfusions performed in 20 patients with Rh isoimmunisation. alpha Fetoprotein concentration was assayed in maternal blood taken before, and immediately after each transfusion and three and 24 hours later. An increase of 50% or more in the...

journal_title：BMJ (Clinical research ed.)

authors： Nicolini U,Kochenour NK,Greco P,Letsky EA,Johnson RD,Contreras M,Rodeck CH

更新日期：1988-11-26 00:00:00

abstract：OBJECTIVE:To estimate the effectiveness of delivering an anthelmintic through a community child health programme on the weight gain of preschool children in Uganda. DESIGN:Cluster randomised controlled trial. SETTING:Eastern Uganda. PARTICIPANTS:48 parishes participating in a new programme for child health: 24 offer...

journal_title：BMJ (Clinical research ed.)

authors： Alderman H,Konde-Lule J,Sebuliba I,Bundy D,Hall A

更新日期：2006-07-15 00:00:00

abstract：OBJECTIVE:To determine whether the intervention of a physiotherapist improved mobility in patients seen more than one year after stroke. DESIGN:Randomised crossover trial comparing two groups offered intervention by a physiotherapist, one immediately after entry into the trial and the other after a delay of three mont...

journal_title：BMJ (Clinical research ed.)

authors： Wade DT,Collen FM,Robb GF,Warlow CP

更新日期：1992-03-07 00:00:00

abstract：OBJECTIVE:To determine whether the novel avian influenza H7N9 virus can transmit from person to person and its efficiency. DESIGN:Epidemiological investigations conducted after a family cluster of two patients with avian H7N9 in March 2013. SETTING:Wuxi, Eastern China. PARTICIPANTS:Two patients, their close contacts...

journal_title：BMJ (Clinical research ed.)

authors： Qi X,Qian YH,Bao CJ,Guo XL,Cui LB,Tang FY,Ji H,Huang Y,Cai PQ,Lu B,Xu K,Shi C,Zhu FC,Zhou MH,Wang H

更新日期：2013-08-06 00:00:00

abstract：OBJECTIVE:To determine the contribution of inheritance to the incidence of squamous cell carcinoma of the head and neck. DESIGN:Historical cohort study. First degree relatives of cases with squamous cell carcinoma of the head and neck made up the exposed cohort and first degree relatives of spouses of cases made up th...

journal_title：BMJ (Clinical research ed.)

authors： Foulkes WD,Brunet JS,Sieh W,Black MJ,Shenouda G,Narod SA

更新日期：1996-09-21 00:00:00

abstract：OBJECTIVE:To assess the association between macrolide antibiotics prescribing during pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity disorder, and autism spectrum disorder in children. DESIGN:Population based cohort study. SETTING:The UK Clinical Practice Research Datalink...

journal_title：BMJ (Clinical research ed.)

authors： Fan H,Gilbert R,O'Callaghan F,Li L

更新日期：2020-02-19 00:00:00

abstract：OBJECTIVE:To systematically review the accuracy of physicians' clinical predictions of survival in terminally ill cancer patients. DATA SOURCES:Cochrane Library, Medline (1996-2000), Embase, Current Contents, and Cancerlit databases as well as hand searching. STUDY SELECTION:Studies were included if a physician's tem...

journal_title：BMJ (Clinical research ed.)

authors： Glare P,Virik K,Jones M,Hudson M,Eychmuller S,Simes J,Christakis N

更新日期：2003-07-26 00:00:00

abstract：:Current services for those with mental disorders show two trends. Psychiatric services are becoming concentrated on the care of those with "severe mental illness," largely (but unjustifiably) synonymous with chronic psychosis. The retreat of psychiatry from the care of those with non-psychotic mental disorders has hel...

journal_title：BMJ (Clinical research ed.)

authors： Wessely S

更新日期：1996-07-20 00:00:00

abstract：OBJECTIVE:To evaluate the performance of a rapid test for chlamydia with first void male urine samples as a potential tool for diagnosis and screening of chlamydial infection in men. DESIGN:Evaluation of test performance in prospective cohort study. Settings A young people's sexual health centre (site 1) and a genitou...

journal_title：BMJ (Clinical research ed.)

authors： Nadala EC,Goh BT,Magbanua JP,Barber P,Swain A,Alexander S,Laitila V,Michel CE,Mahilum-Tapay L,Ushiro-Lumb I,Ison C,Lee HH

更新日期：2009-07-28 00:00:00

abstract：OBJECTIVES:To determine the number and geographical distribution of general practitioners in the NHS who qualified medically in South Asia and to project their numbers as they retire. DESIGN:Retrospective analysis of yearly data and projection of future trends. SETTING:England and Wales. SUBJECTS:General practitione...

journal_title：BMJ (Clinical research ed.)

authors： Taylor DH Jr,Esmail A

更新日期：1999-01-30 00:00:00

abstract：OBJECTIVE:To identify the factors associated with diabetic ketoacidosis at diagnosis of type 1 diabetes in children and young adults. DESIGN:Systematic review. DATA SOURCES:PubMed, EMBASE, Web of Science, Scopus, and Cinahl and article reference lists. STUDY SELECTION:Cohort studies including unselected groups of ch...

journal_title：BMJ (Clinical research ed.)

authors： Usher-Smith JA,Thompson MJ,Sharp SJ,Walter FM

更新日期：2011-07-07 00:00:00

abstract：OBJECTIVE:To find out whether enalapril or ramipril causes the sensitivity of the cough reflex to change or symptomatic cough to develop in patients with hypertension. DESIGN:Prospective, placebo controlled, double blind, randomised crossover study. SETTING:Academic units of clinical pharmacology and medicine. PATIE...

journal_title：BMJ (Clinical research ed.)

authors： McEwan JR,Choudry N,Street R,Fuller RW

更新日期：1989-07-01 00:00:00

abstract：:One hundred and two patients returned structured questionnaires sent to clinics for sickle cell disease in the United Kingdom in order to gain greater insight into the patients' perception of painful crises. Most patients who suffer pain crises experience a prodromal stage that should be investigated further to find o...

journal_title：BMJ (Clinical research ed.)

authors： Murray N,May A

更新日期：1988-08-13 00:00:00

abstract：OBJECTIVE:To determine whether in a patient with spontaneous pneumothorax the presence or absence of a pleural leak can be shown at the time of manual aspiration by use of a marker gas. Also, to find out if the technique can predict whether manual aspiration will be successful, hence avoiding the need for intercostal t...

journal_title：BMJ (Clinical research ed.)

authors： Seaton D,Yoganathan K,Coady T,Barker R

更新日期：1991-02-02 00:00:00

abstract：:The place of balloon dilatation of the aortic valve in the treatment of calcific aortic stenosis is controversial. Thirty two patients (mean age 76) in whom valve replacement was contraindicated were followed up for three to 24 months (mean 8); 25 were in functional class III or IV according to the New York Heart Asso...

journal_title：BMJ (Clinical research ed.)

authors： Sprigings DC,Jackson G,Chambers JB,Monaghan MJ,Thomas SD,Meany TB,Jewitt DE

更新日期：1988-10-22 00:00:00

abstract：OBJECTIVES:To determine the impact on teenage pregnancy of interventions that address the social disadvantage associated with early parenthood and to assess the appropriateness of such interventions for young people in the United Kingdom. DESIGN:Systematic review, including a statistical meta-analysis of controlled tr...

journal_title：BMJ (Clinical research ed.)

authors： Harden A,Brunton G,Fletcher A,Oakley A

更新日期：2009-11-12 00:00:00