Cohort study of hepatotoxicity associated with nimesulide and other non-steroidal anti-inflammatory drugs.

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：OBJECTIVE:To determine the risk factors for neonatal encephalopathy among term infants in a developing country. DESIGN:Unmatched case-control study. SETTING:Principal maternity hospital of Kathmandu, Nepal. SUBJECTS:All 131 infants with neonatal encephalopathy from a population of 21 609 infants born over an 18 mont...

journal_title：BMJ (Clinical research ed.)

authors： Ellis M,Manandhar N,Manandhar DS,Costello AM

更新日期：2000-05-06 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of different screening strategies for abdominal aortic aneurysm in men, from the perspective of a national health service. SETTING:Screening units at regional hospitals. PARTICIPANTS:Hypothetical cohort of 65 year old men from the general population. MAIN OUTCOME MEASURES:C...

journal_title：BMJ (Clinical research ed.)

authors： Søgaard R,Laustsen J,Lindholt JS

更新日期：2012-07-05 00:00:00

abstract：OBJECTIVE:To report the percentage of graduates from British medical schools who eventually practise medicine in the British NHS. DESIGN:Cohort studies using postal questionnaires, employment data, and capture-recapture analysis. SETTING:Great Britain. SUBJECTS:32 430 graduates from all British medical schools in ni...

journal_title：BMJ (Clinical research ed.)

authors： Goldacre MJ,Davidson JM,Lambert TW

更新日期：2009-06-03 00:00:00

abstract：OBJECTIVE:To investigate the risk factors for HIV infection in patients attending clinics for sexually transmitted diseases in India. DESIGN:Descriptive study of HIV serology, risk behaviour, and findings on physical examination. SUBJECTS:2800 patients presenting to outpatient clinics between 13 May 1993 and 15 July ...

journal_title：BMJ (Clinical research ed.)

authors： Rodrigues JJ,Mehendale SM,Shepherd ME,Divekar AD,Gangakhedkar RR,Quinn TC,Paranjape RS,Risbud AR,Brookmeyer RS,Gadkari DA

更新日期：1995-07-29 00:00:00

abstract：OBJECTIVE:To synthesise the views of patients and carers in decision making regarding treatment for chronic kidney disease, and to determine which factors influence those decisions. DESIGN:Systematic review of qualitative studies of decision making and choice for dialysis, transplantation, or palliative care, and them...

journal_title：BMJ (Clinical research ed.)

authors： Morton RL,Tong A,Howard K,Snelling P,Webster AC

更新日期：2010-01-19 00:00:00

abstract：OBJECTIVE:To investigate the association between several types of soy products and all cause and cause specific mortality. DESIGN:Population based cohort study. SETTING:Japan Public Health Centre-based Prospective Study, which includes 11 public health centre areas in Japan. PARTICIPANTS:92 915 participants (42 750 ...

journal_title：BMJ (Clinical research ed.)

authors： Katagiri R,Sawada N,Goto A,Yamaji T,Iwasaki M,Noda M,Iso H,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2020-01-29 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of teaching general practitioners skills in brief cognitive behaviour therapy. DESIGN:Parallel group, cluster randomised, controlled trial of an educational package on cognitive behaviour therapy. SETTING:General practices in north London. PARTICIPANTS:84 general practitioner pr...

journal_title：BMJ (Clinical research ed.)

authors： King M,Davidson O,Taylor F,Haines A,Sharp D,Turner R

更新日期：2002-04-20 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of classroom based cognitive behavioural therapy with attention control and usual school provision for adolescents at high risk of depression. DESIGN:Three arm parallel cluster randomised controlled trial. SETTING:Eight UK secondary schools. PARTICIPANTS:Adolescents (n=5030) ag...

journal_title：BMJ (Clinical research ed.)

authors： Stallard P,Sayal K,Phillips R,Taylor JA,Spears M,Anderson R,Araya R,Lewis G,Millings A,Montgomery AA

更新日期：2012-10-05 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of two peritendinous autologous blood injections in addition to a standardised eccentric calf strengthening programme in improving pain and function in patients with mid-portion Achilles tendinopathy. DESIGN:Single centre, participant and single assessor blinded, parallel group, r...

journal_title：BMJ (Clinical research ed.)

authors： Bell KJ,Fulcher ML,Rowlands DS,Kerse N

更新日期：2013-04-18 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVE:This study updates work published in 1998, which found that of 47 rating instruments appearing on websites offering health information, 14 described how they were developed, five provided instructions for use, and none reported the interobserver reliability and construct validity of the measurements. DESIGN:...

journal_title：BMJ (Clinical research ed.)

authors： Gagliardi A,Jadad AR

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVE:To determine which treatments for preventing coronary heart disease should be offered to which patients by assessing their incremental cost effectiveness. DESIGN:Modelling study. DATA SOURCES:Cost estimates (for NHS) and estimates of effectiveness obtained for aspirin, antihypertensive drugs, statins and cl...

journal_title：BMJ (Clinical research ed.)

authors： Marshall T

更新日期：2003-11-29 00:00:00

abstract：:The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funde...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,clinical adviser,.,Martin R,NIHR Dissemination Centre.

更新日期：2019-08-27 00:00:00

abstract：OBJECTIVE:To characterise the complete case series of influenza A/H7N9 infections as of 27 May 2013, detected by China's national sentinel surveillance system for influenza-like illness. DESIGN:Case series. SETTING:Outpatient clinics and emergency departments of 554 sentinel hospitals across 31 provinces in mainland ...

journal_title：BMJ (Clinical research ed.)

authors： Ip DK,Liao Q,Wu P,Gao Z,Cao B,Feng L,Xu X,Jiang H,Li M,Bao J,Zheng J,Zhang Q,Chang Z,Li Y,Yu J,Liu F,Ni MY,Wu JT,Cowling BJ,Yang W,Leung GM,Yu H

更新日期：2013-06-24 00:00:00

abstract：OBJECTIVE:To identify the attitudes of general practitioners towards the use of thermometers in general practice. DESIGN:Postal questionnaire survey. SETTING:All general practitioners in the catchment area of Frimley Park Hospital, Surrey. SUBJECTS:145 general practitioners. MAIN OUTCOME MEASURES:Answers to questio...

journal_title：BMJ (Clinical research ed.)

authors： Clarke S

更新日期：1992-04-11 00:00:00

abstract：OBJECTIVE:To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. DESIGN:Two epidemiological surveys 20 years apart. Identical questions were asked about asthma, hay fever, and respiratory symptoms at each survey. SETTING:Renfrew and Paisley, two towns in the west of Scotland....

journal_title：BMJ (Clinical research ed.)

authors： Upton MN,McConnachie A,McSharry C,Hart CL,Smith GD,Gillis CR,Watt GC

更新日期：2000-07-08 00:00:00

abstract：:The instrument through which a commissioner purchases health services from a provider is, as in other walks of life, a contract, so considerable importance has been attached by the NHS Executive to the contracting mechanism. A contract should in theory influence the quality of the service provided, but they are in man...

journal_title：BMJ (Clinical research ed.)

authors： Hopkins A,Solomon JK

更新日期：1996-08-24 00:00:00

abstract：:To assess the prevalence of both diagnosed and undiagnosed diabetes mellitus in an area of predominantly Asian population the Coventry diabetes study is carrying out house to house screening for diabetes in people aged 20 and over in Foleshill, Coventry. In the first five of 12 areas to be studied 2130 of 2283 Asian (...

journal_title：BMJ (Clinical research ed.)

authors： Simmons D,Williams DR,Powell MJ

更新日期：1989-01-07 00:00:00

abstract：:The "four principles plus scope" approach provides a simple, accessible, and culturally neutral approach to thinking about ethical issues in health care. The approach, developed in the United States, is based on four common, basic prima facie moral commitments--respect for autonomy, beneficence, nonmaleficence, and ju...

journal_title：BMJ (Clinical research ed.)

authors： Gillon R

更新日期：1994-07-16 00:00:00

abstract：:With the aim of promoting the informed choice of pregnant women, staff and pregnant women at two urban hospitals were offered leaflets summarising the best available evidence about the effectiveness of routine ultrasonography in early pregnancy. Ultrasonographers doubted the credibility of the evidence and were concer...

journal_title：BMJ (Clinical research ed.)

authors： Oliver S,Rajan L,Turner H,Oakley A,Entwistle V,Watt I,Sheldon TA,Rosser J

更新日期：1996-11-16 00:00:00

abstract：OBJECTIVE:To quantify the association between stressful life events and exacerbations of multiple sclerosis. DATA SOURCES:PubMed, PsychInfo, and Psychological Abstracts searched for empirical papers from 1965 to February 2003 with terms "stress", "trauma", and "multiple sclerosis". REVIEW METHODS:Three investigators ...

journal_title：BMJ (Clinical research ed.)

authors： Mohr DC,Hart SL,Julian L,Cox D,Pelletier D

更新日期：2004-03-27 00:00:00

abstract：OBJECTIVES:To estimate survival after a diagnosis of dementia in primary care, compared with people without dementia, and to determine incidence of dementia. DESIGN:Cohort study using data from The Health Improvement Network (THIN), a primary care database. SETTING:353 general practices in the United Kingdom providin...

journal_title：BMJ (Clinical research ed.)

authors： Rait G,Walters K,Bottomley C,Petersen I,Iliffe S,Nazareth I

更新日期：2010-08-05 00:00:00

abstract：:Medical audit has its critics, who point to the large sums of NHS cash that seem to be disappearing down a medical plughole. These criticisms are recognised by medical audit advisory groups but there are many reasons why the work of these groups has not yet resulted in many publications in journals or bumped up health...

journal_title：BMJ (Clinical research ed.)

authors： Johnson R

更新日期：1994-07-09 00:00:00

abstract：OBJECTIVE:To use funnel plots and cumulative funnel plots to compare in-hospital outcome data for operators undertaking percutaneous coronary interventions with predicted results derived from a validated risk score to allow for early detection of variation in performance. DESIGN:Analysis of prospectively collected dat...

journal_title：BMJ (Clinical research ed.)

authors： Kunadian B,Dunning J,Roberts AP,Morley R,Twomey D,Hall JA,Sutton AG,Wright RA,Muir DF,de Belder MA

更新日期：2008-04-26 00:00:00

abstract：:The meaning of the GP contract has changed since the last major upheaval in the mid-1960s. The government has always dealt with general practitioners as independent contractors, but the way in which it treated them in 1990 was entirely different from the way in which they were treated in 1966. In 1966, the profession'...

journal_title：BMJ (Clinical research ed.)

authors： Lewis J

更新日期：1997-03-22 00:00:00

abstract：OBJECTIVE:To compare the effects of treatments for coronavirus disease 2019 (covid-19). DESIGN:Living systematic review and network meta-analysis. DATA SOURCES:WHO covid-19 database, a comprehensive multilingual source of global covid-19 literature, up to 3 December 2020 and six additional Chinese databases up to 12 ...

journal_title：BMJ (Clinical research ed.)

authors： Siemieniuk RA,Bartoszko JJ,Ge L,Zeraatkar D,Izcovich A,Kum E,Pardo-Hernandez H,Rochwerg B,Lamontagne F,Han MA,Liu Q,Agarwal A,Agoritsas T,Chu DK,Couban R,Darzi A,Devji T,Fang B,Fang C,Flottorp SA,Foroutan F,Ghad

更新日期：2020-07-30 00:00:00

abstract：:The studySheppard JP, Stevens S, Stevens R, Martin U, Mant J, Hobbs R, McManus R. Benefits and harms of antihypertensive treatment in low-risk patients with mild hypertension.Published on 1 December 2018 JAMA Intern Med 2018;178:1626-34.This project was funded by a grant from the National Institute for Health Research...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Lamont T,Martin R,NIHR Dissemination Centre.

更新日期：2019-02-15 00:00:00

abstract：OBJECTIVE:To evaluate the effect of financial incentives on four clinical quality indicators common to pay for performance plans in the United Kingdom and at Kaiser Permanente in California. DESIGN:Longitudinal analysis. SETTING:35 medical facilities of Kaiser Permanente Northern California, 1997-2007. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Lester H,Schmittdiel J,Selby J,Fireman B,Campbell S,Lee J,Whippy A,Madvig P

更新日期：2010-05-11 00:00:00

abstract：OBJECTIVES:To determine whether there are important differences in performance between group practices and singlehanded general practitioners and the extent to which any differences are explained by practice characteristics such as deprivation. DESIGN:Cross sectional survey. SETTING:206 singlehanded practices and 606...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Pringle M,Coupland C,Hammersley V,Wilson A

更新日期：2001-08-11 00:00:00