Results of the "GER-e-TEC" Experiment Involving the Use of an Automated Platform to Detect the Exacerbation of Geriatric Syndromes.

Abstract:

INTRODUCTION:Telemedicine is believed to be helpful in managing patients suffering from chronic diseases, in particular elderly patients with numerous accompanying conditions. This was the basis for the "GERIATRICS and e-Technology (GER-e-TEC) study", which was an experiment involving the use of the smart MyPredi™ e-platform to automatically detect the exacerbation of geriatric syndromes. METHODS:The MyPredi™ platform is connected to a medical analysis system that receives physiological data from medical sensors in real time and analyzes this data to generate (when necessary) alerts. These alerts are issued in the event that the health of a patient deteriorates due to an exacerbation of their chronic diseases. An experiment was conducted between 24 September 2019 and 24 November 2019 to test this alert system. During this time, the platform was used on patients being monitored in an internal medicine unit at the University Hospital of Strasbourg. The alerts were compiled and analyzed in terms of sensitivity, specificity, and positive and negative predictive values with respect to clinical data. The results of the experiment are provided below. RESULTS:A total of 36 patients were monitored remotely, 21 of whom were male. The mean age of the patients was 81.4 years. The patients used the telemedicine solution for an average of 22.1 days. The telemedicine solution took a total of 147,703 measurements while monitoring the geriatric risks of the entire patient group. An average of 226 measurements were taken per patient per day. The telemedicine solution generated a total of 1611 alerts while assessing the geriatric risks of the entire patient group. For each geriatric risk, an average of 45 alerts were emitted per patient, with 16 of these alerts classified as "low", 12 classified as "medium", and 20 classified as "critical". In terms of sensitivity, the results were 100% for all geriatric risks and extremely satisfactory in terms of positive and negative predictive values. In terms of survival analysis, the number of alerts had an impact on the duration of hospitalization due to decompensated heart failure, a deterioration in the general condition, and other reasons. CONCLUSION:The MyPredi™ telemedicine system allows the generation of automatic, non-intrusive alerts when the health of a patient deteriorates due to risks associated with geriatric syndromes.

journal_name

J Clin Med

authors

Zulfiqar AA,Vaudelle O,Hajjam M,Geny B,Talha S,Letourneau D,Hajjam J,Erve S,Hajjam El Hassani A,Andrès E

doi

10.3390/jcm9123836

subject

Has Abstract

pub_date

2020-11-26 00:00:00

issue

12

issn

2077-0383

pii

jcm9123836

journal_volume

9

pub_type

杂志文章
  • Affected Ovary Relative Volume: A Novel Sonographic Predictor of Ovarian Reserve in Patients with Unilateral Endometrioma-A Pilot Study.

    abstract:BACKGROUND:The assessment of ovarian reserve in the case of endometrioma is of pivotal importance for planning a tailored management. However, both the antral follicle count (AFC) and the antimüllerian hormone (AMH) dosage are subject to a fair degree of variability in ovarian endometriosis. This study aimed to identif...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9124076

    authors: Cosma S,Carosso AR,Moretto M,Borella F,Ferraioli D,Bovetti M,Gervasoni F,Filippini C,Revelli A,Ferrero S,Benedetto C

    更新日期:2020-12-17 00:00:00

  • Decision Support for the Optimization of Provider Staffing for Hospital Emergency Departments with a Queue-Based Approach.

    abstract::: Deployment or distribution of valuable medical resources has emerged as an increasing challenge to hospital administrators and health policy makers. The hospital emergency department (HED) census and workload can be highly variable. Improvement of emergency services is an important stage in the development of the he...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8122154

    authors: Jiang FC,Shih CM,Wang YM,Yang CT,Chiang YJ,Lee CH

    更新日期:2019-12-05 00:00:00

  • DJ-1 in Parkinson's Disease: Clinical Insights and Therapeutic Perspectives.

    abstract::Mutations in the protein DJ-1 cause autosomal recessive forms of Parkinson's disease (PD) and oxidized DJ-1 is found in the brains of idiopathic PD individuals. While several functions have been ascribed to DJ-1 (most notably protection from oxidative stress), its contribution to PD pathogenesis is not yet clear. Here...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm8091377

    authors: Repici M,Giorgini F

    更新日期:2019-09-03 00:00:00

  • A New Method of Measuring the Volumetric Change of Alveolar Bone Around Dental Implants Using Computed Tomography.

    abstract::This study proposes a method for measuring the volumetric change of alveolar bone after dental implant surgery using computed tomography (CT). A total of 40 implants in 20 patients (15 males and 5 females) were selected. The types of implants used were group 1: 24 CMI IS-II Active implants (Neobiotech Co., Seoul, Repu...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9041238

    authors: Lim YW,Lim YJ,Kim B,Lee SP

    更新日期:2020-04-24 00:00:00

  • Investigation of Meibomian Gland Function and Dry Eye Disease in Patients with Graves' Ophthalmopathy.

    abstract::We prospectively evaluated the relationship between meibomian gland dysfunction (MGD) and Graves' ophthalmopathy (GO) in 19 patients (38 eyes) with subjective dry eye symptoms, compared to 14 age-matched normal participants (14 eyes). Extraocular muscle and lacrimal gland enlargement were evaluated by magnetic resonan...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9092814

    authors: Inoue S,Kawashima M,Arita R,Kozaki A,Tsubota K

    更新日期:2020-08-31 00:00:00

  • Cellular Proliferation, Dermal Repair, and Microbiological Effectiveness of Ultrasound-Assisted Wound Debridement (UAW) Versus Standard Wound Treatment in Complicated Diabetic Foot Ulcers (DFU): An Open-Label Randomized Controlled Trial.

    abstract::We aimed to evaluate the effects of ultrasound-assisted wound (UAW) debridement on cellular proliferation and dermal repair in complicated diabetic foot ulcers as compared to diabetic foot ulcers receiving surgical/sharp wound debridement. A randomized controlled trial was performed involving 51 outpatients with compl...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9124032

    authors: Lázaro-Martínez JL,Álvaro-Afonso FJ,Sevillano-Fernández D,García-Álvarez Y,Sanz-Corbalan I,García-Morales E

    更新日期:2020-12-13 00:00:00

  • Platelet Depletion is Effective in Ameliorating Anxiety-Like Behavior and Reducing the Pro-Inflammatory Environment in the Hippocampus in Murine Experimental Autoimmune Encephalomyelitis.

    abstract::The neuropsychiatric symptoms of multiple sclerosis (MS), such as anxiety and depression, can result from disease activity itself as well as psychological reaction to an unfavorable diagnosis. Accordingly, the literature reports evidence of increased anxiety-like behavior in experimental autoimmune encephalomyelitis (...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8020162

    authors: Kocovski P,Jiang X,D'Souza CS,Li Z,Dang PT,Wang X,Chen W,Peter K,Hale MW,Orian JM

    更新日期:2019-02-01 00:00:00

  • Validation of the Liver Disease Quality of Life Instrument 1.0 in Patients with Chronic Hepatitis B: A Prospective Study.

    abstract::The purpose of this study was to report on the clinical usefulness of the Liver Disease Quality of Life Instrument (LDQOL) 1.0, which was prospectively measured in chronic hepatitis B patients. We regularly followed up with patients with chronic hepatitis B between 2008 and 2010 who were enrolled in the study, and the...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8050656

    authors: Ha Y,Hwang S,Chon YE,Kim MN,Lee JH,Hwang SG

    更新日期:2019-05-10 00:00:00

  • Tricyclic Antidepressant Use and Risk of Fractures: A Meta-Analysis of Cohort Studies through the Use of Both Frequentist and Bayesian Approaches.

    abstract:BACKGROUND:Research findings regarding the association between tricyclic antidepressant (TCA) treatment and the risk of fracture are not consistent; we aimed to assess whether people who take TCAs are at an increased fracture risk. METHODS:Relevant studies published through June 2020 were identified through database s...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm9082584

    authors: Wu Q,Xu Y,Bao Y,Alvarez J,Gonzales ML

    更新日期:2020-08-10 00:00:00

  • Impact of Diabetes Mellitus on Outcomes after High-Risk Interventional Coronary Procedures.

    abstract::An increasing number of patients with coronary artery disease are at high operative risk due to advanced age, severe comorbidities, complex coronary anatomy, and reduced ejection fraction. Consequently, these high-risk patients are often offered percutaneous coronary intervention (PCI) as an alternative to coronary ar...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9113414

    authors: Johannsen L,Soldat J,Krueger A,Mahabadi AA,Dykun I,Totzeck M,Jánosi RA,Rassaf T,Al-Rashid F

    更新日期:2020-10-25 00:00:00

  • Non-Pharmacological Interventions for Post-Stroke Fatigue: Systematic Review and Network Meta-Analysis.

    abstract::Post-stroke fatigue (PSF) is one of the most serious sequelae, which often interferes with the rehabilitation process and impairs the functional recovery of patients. Due to insufficient evidence, it is unclear which specific pharmacological interventions should be recommended. Therefore, in this paper, we compare the...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm9030621

    authors: Su Y,Yuki M,Otsuki M

    更新日期:2020-02-25 00:00:00

  • Long-Term Effects of Spironolactone on Kidney Function and Hyperkalemia-Associated Hospitalization in Patients with Chronic Kidney Disease.

    abstract:BACKGROUND:Spironolactone, a non-selective mineralocorticoid receptor antagonist, can protect against cardiac fibrosis and left ventricular dysfunction, and improve endothelial dysfunction and proteinuria. However, the safety and effects of spironolactone on patient-centered cardiovascular and renal endpoints remain un...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm7110459

    authors: Yang CT,Kor CT,Hsieh YP

    更新日期:2018-11-21 00:00:00

  • High Molecular Weight Hyaluronan Promotes Corneal Nerve Growth in Severe Dry Eyes.

    abstract::The purpose of this study was to investigate the effect of high molecular weight hyaluronan (HMWHA) eye drops on subbasal corneal nerves in patients suffering from severe dry eye disease (DED) and to evaluate the damage of subbasal corneal nerves associated with severe DED. Designed as an international, multicenter st...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9123799

    authors: van Setten GB,Stachs O,Dupas B,Turhan SA,Seitz B,Reitsamer H,Winter K,Horwath-Winter J,Guthoff RF,Müller-Lierheim WGK

    更新日期:2020-11-24 00:00:00

  • APEX1 Expression as a Potential Diagnostic Biomarker of Clear Cell Renal Cell Carcinoma and Hepatobiliary Carcinomas.

    abstract::Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APEX1) has been known to play key roles in DNA repair, the regulation of diverse transcriptional activity, and cellular responses to redox activity. This study aimed to examine serum APEX1 (s-APEX1) expression as a possible screening biomarker for clear cel...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8081151

    authors: Kim JM,Yeo MK,Lim JS,Song IS,Chun K,Kim KH

    更新日期:2019-08-01 00:00:00

  • Genes and Variants Underlying Human Congenital Lactic Acidosis-From Genetics to Personalized Treatment.

    abstract::Congenital lactic acidosis (CLA) is a rare condition in most instances due to a range of inborn errors of metabolism that result in defective mitochondrial function. Even though the implementation of next generation sequencing has been rapid, the diagnosis rate for this highly heterogeneous allelic condition remains l...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8111811

    authors: Bravo-Alonso I,Navarrete R,Vega AI,Ruíz-Sala P,García Silva MT,Martín-Hernández E,Quijada-Fraile P,Belanger-Quintana A,Stanescu S,Bueno M,Vitoria I,Toledo L,Couce ML,García-Jiménez I,Ramos-Ruiz R,Martín MÁ,Desviat LR,Ug

    更新日期:2019-11-01 00:00:00

  • Intraosseous Bioplasty for a Subchondral Cyst in the Lateral Condyle of Femur.

    abstract::Several conditions can lead to the development of a subchondral cyst. The mechanism by which the cysts form, their location, and their severity depend on the underlying pathology, although the exact pathogenesis is not fully elucidated. Treatment options vary according to the location of the cyst, with less invasive p...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9051358

    authors: Potty AGR,Gupta A,Rodriguez HC,Stone IW,Maffulli N

    更新日期:2020-05-06 00:00:00

  • Surgical Treatment of Paediatric Chronic Rhinosinusitis.

    abstract::Rhinosinusitis (RS) is a common disease in children, significantly affecting their quality of life. Chronic rhinosinusitis (CRS) is frequently linked to other respiratory diseases, including asthma. Children affected by CRS may be candidates for surgery in the case of failure of maximal medical therapy comprising thre...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm8050684

    authors: Torretta S,Guastella C,Ibba T,Gaffuri M,Pignataro L

    更新日期:2019-05-15 00:00:00

  • Risk Factors of Intervertebral Disc Pathology-A Point of View Formerly and Today-A Review.

    abstract::Intervertebral disc pathology is a common disorder that can be caused by genetic, mechanical, and behavioral factors; however, it is possible to slow its progression. Although environmental and behavioral factors were previously considered to be the sole causes of intervertebral disc pathologies such as disc herniatio...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm10030409

    authors: Zielinska N,Podgórski M,Haładaj R,Polguj M,Olewnik Ł

    更新日期:2021-01-21 00:00:00

  • Prognosis-Predicting Model Based on [18F]fluorodeoxyglucose PET Metabolic Parameters in Locally Advanced Cervical Cancer Patients Treated with Concurrent Chemoradiotherapy: Multi-Center Retrospective Study.

    abstract::This study aimed to develop a prognosis-predicting model based on [18F]fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and clinicopathologic factors in locally advanced cervical cancer patients treated with concurrent chemoradiotherapy (CCRT). The medical records of 270 locally adv...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9020427

    authors: Lee WK,Chong GO,Jeong SY,Lee HJ,Park SH,Ryu JM,Choi YS,Kang S,Koo YJ,Lee DH,Kong E,Lee SW

    更新日期:2020-02-05 00:00:00

  • Diabetic Cardiovascular Autonomic Neuropathy, the Handgrip Test and Ambulatory Blood Pressure Monitoring Parameters: Are There Any Diagnostic Implications?

    abstract::Cardiovascular autonomic neuropathy (CAN) is a common complication of diabetes mellitus. Cardiovascular reflex tests (CARTs) are the gold standard in the diagnosis of CAN, but the handgrip test is no longer recommended to be performed. Previously, the inverse association between the presence of hypertension and handgr...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9103322

    authors: Kempler M,Hajdú N,Putz Z,Istenes I,Vági O,Békeffy M,Schnabel K,Kempler P,Körei AE

    更新日期:2020-10-16 00:00:00

  • Reliability of the Scapula Reposition Test in Subjects with Rotator Cuff Tendinopathy and Scapular Dyskinesis.

    abstract::The Scapula Reposition Test (SRT) is proposed to determine if a relationship exists between scapular dyskinesis and shoulder pathology. The purpose of this study was to evaluate intra-rater and inter-rater reliability of the SRT in subjects with rotator cuff tendinopathy and scapular dyskinesis. In addition, we compar...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9010080

    authors: Fernandez-Matias R,Gallardo-Zamora P,Sanchez-Aguilera CL,Mardones-Varela H,Gallego-Izquierdo T,Pecos-Martin D

    更新日期:2019-12-28 00:00:00

  • Association between Primary Perioperative CEA Ratio, Tumor Site, and Overall Survival in Patients with Colorectal Cancer.

    abstract::There are differences in the incidence, clinical presentation, molecular pathogenesis, and outcome of colorectal cancer (CRC) based on tumor location. Emerging research suggests that the perioperative carcinoembryonic antigen (CEA) ratio (post-op/pre-op CEA) is a prognostic factor for CRC patients. We aimed to determi...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9123848

    authors: Odeny TA,Farha N,Hildebrandand H,Allen J,Vazquez W,Martinez M,Paluri RK,Kasi A

    更新日期:2020-11-27 00:00:00

  • Invasive Fungal Diseases in Kidney Transplant Recipients: Risk Factors for Mortality.

    abstract:BACKGROUND:Invasive fungal disease (IFD) is common in solid organ transplant (SOT) recipients and contributes to high morbidity and mortality. Although kidney transplantation (KT) is a commonly performed SOT, data on the risk factors for IFD-related mortality are limited. METHODS:A 1:2 retrospective case-control study...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9061824

    authors: Seok H,Huh K,Cho SY,Kang CI,Chung DR,Huh WS,Park JB,Peck KR

    更新日期:2020-06-11 00:00:00

  • Circulating Lactonase Activity but Not Protein Level of PON-1 Predicts Adverse Outcomes in Subjects with Chronic Kidney Disease.

    abstract::The burden of cardiovascular disease and death in chronic kidney disease (CKD) outpaces that of the other diseases and is not adequately described by traditional risk factors alone. Diminished activity of paraoxonase (PON)-1 is associated with increased oxidant stress, a common feature underlying the pathogenesis of C...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8071034

    authors: Mohammed CJ,Xie Y,Brewster PS,Ghosh S,Dube P,Sarsour T,Kleinhenz AL,Crawford EL,Malhotra D,James RW,Kalra PA,Haller ST,Kennedy DJ

    更新日期:2019-07-15 00:00:00

  • Associations among Bruxism, Gastroesophageal Reflux Disease, and Tooth Wear.

    abstract::The relationship between bruxism and tooth wear is contentious in the literature. The pathophysiological processes of tooth wear may be complicated by the relationship between bruxism and gastroesophageal reflux disease (GERD). The objective of this study was to evaluate the associations among bruxism, GERD, and tooth...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm7110417

    authors: Li Y,Yu F,Niu L,Hu W,Long Y,Tay FR,Chen J

    更新日期:2018-11-06 00:00:00

  • Factors Associated with Decisions for Initial Dosing, Up-Titration of Propiverine and Treatment Outcomes in Overactive Bladder Syndrome Patients in a Non-Interventional Setting.

    abstract::Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Da...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm10020311

    authors: Amiri M,Schneider T,Oelke M,Murgas S,Michel MC

    更新日期:2021-01-15 00:00:00

  • Circulating Endometrial Cells: A New Source of Information on Endometriosis Dynamics.

    abstract::The focus of the presented work was to isolate and characterize circulating endometrial cells (CECs) enriched from peripheral blood (PB) of patients with diagnosed endometriosis. The molecular characteristics of CECs could be supportive for an understanding of endometriosis pathogenesis and treatment decisions in the ...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8111938

    authors: Pospisilova E,Kiss I,Souckova H,Tomes P,Spicka J,Matkowski R,Jedryka M,Ferrero S,Bobek V,Kolostova K

    更新日期:2019-11-11 00:00:00

  • Sjögren's Syndrome: The Clinical Spectrum of Male Patients.

    abstract:BACKGROUND:To compare the clinical, serological and histologic features between male and female patients with Sjögren's syndrome (SS) and explore the potential effect of gender on lymphoma development. METHODS:From a multicenter population (Universities of Udine, Pisa and Athens, Harokopion and Ioannina (UPAHI)) consi...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9082620

    authors: Chatzis L,Pezoulas VC,Ferro F,Gandolfo S,Donati V,Binutti M,Callegher SZ,Venetsanopoulou A,Zampeli E,Mavrommati M,Argyropoulou OD,Michalopoulos G,Voulgari PV,Exarchos T,Baldini C,Skopouli FN,Fotiadis DI,De Vita S,Mout

    更新日期:2020-08-12 00:00:00

  • An Evaluation of Acylated Ghrelin and Obestatin Levels in Childhood Obesity and Their Association with Insulin Resistance, Metabolic Syndrome, and Oxidative Stress.

    abstract:BACKGROUND:Ghrelin is a 28-amino acid peptide with an orexigenic property, which is predominantly produced by the stomach. Acylated ghrelin is the active form of this hormone. Obestatin is a 23-amino acid peptide which is produced by post-translational modification of a protein precursor that also produces ghrelin. Obe...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm5070061

    authors: Razzaghy-Azar M,Nourbakhsh M,Pourmoteabed A,Nourbakhsh M,Ilbeigi D,Khosravi M

    更新日期:2016-06-23 00:00:00

  • Differential Expression and Clinicopathological Significance of HER2, Indoleamine 2,3-Dioxygenase and PD-L1 in Urothelial Carcinoma of the Bladder.

    abstract:PURPOSE:Evasion of the immune system by cancer cells allows for the progression of tumors. Antitumor immunotherapy has shown remarkable effects in a diverse range of cancers. The aim of this study was to determine the clinicopathological significance of human epidermal growth factor receptor 2 (HER2), indoleamine 2,3-d...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9051265

    authors: Kim D,Kim JM,Kim JS,Kim S,Kim KH

    更新日期:2020-04-27 00:00:00