Abstract:
:Evidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response. Herein, we show that the promising HDVdb genotyping tool available online can lead to wrong genotyping results. The current HDVdb algorithm should be carefully considered as a "beta-version" and warrants algorithm core corrections, as soon as possible, for an optimal and beneficial use.
journal_name
Virusesjournal_title
Virusesauthors
Charre C,le Gal F,Dény P,Scholtès Cdoi
10.3390/v12101066subject
Has Abstractpub_date
2020-09-23 00:00:00issue
10issn
1999-4915pii
v12101066journal_volume
12pub_type
杂志文章相关文献
Viruses-Basel文献大全abstract::Andrias davidianus ranavirus (ADRV) is an emerging viral pathogen that causes severe systemic hemorrhagic disease in Chinese giant salamanders. There is an urgent need for developing an effective vaccine against this fatal disease. In this study, DNA vaccines containing the ADRV 2L gene (pcDNA-2L) and the 58L gene (pc...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10020052
更新日期:2018-01-24 00:00:00
abstract::An equine parvovirus-hepatitis (EqPV-H) has been recently identified in association with equine serum hepatitis, also known as Theiler's disease. This disease was first described by Arnold Theiler in 1918 and is often observed after applications with blood products in equines. So far, the virus has only been described...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11050461
更新日期:2019-05-21 00:00:00
abstract::Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by contin...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v12030285
更新日期:2020-03-05 00:00:00
abstract::The hypothesis is presented that bacteriophage DNA packaging motors have a cycle comprised of bind/release thermal ratcheting with release-associated DNA pushing via ATP-dependent protein folding. The proposed protein folding occurs in crystallographically observed peptide segments that project into an axial channel o...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v2091821
更新日期:2010-09-01 00:00:00
abstract::Influenza A viruses (IAV) have been a major public health threat worldwide, and options for antiviral therapy become increasingly limited with the emergence of drug-resisting virus strains. New and effective anti-IAV drugs, especially for highly pathogenic influenza, with different modes of action, are urgently needed...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12020225
更新日期:2020-02-18 00:00:00
abstract::Astroviral infection is considered to be one of the causes of mammalian diarrheal diseases. It has been shown that astrovirus infections cause varying degrees of diarrhea in turkeys and mice. However, the pathogenesis of porcine astrovirus is unknown. In this study, the virulence of a cytopathic porcine astrovirus (PA...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11121156
更新日期:2019-12-13 00:00:00
abstract::Many geometric forms are found in nature, some of them adhering to mathematical laws or amazing aesthetic rules. One of the best-known examples in microbiology is the icosahedral shape of certain viruses with 20 triangular facets and 12 edges. What is less known, however, is that a complementary object displaying 12 f...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v12070718
更新日期:2020-07-02 00:00:00
abstract::The HIV/AIDS epidemic remains a global health problem, especially in Sub-Saharan Africa. An effective HIV-1 vaccine is therefore badly required to mitigate this ever-expanding problem. Since HIV-1 infects its host through the mucosal surface, a vaccine for the virus needs to trigger mucosal as well as systemic immune ...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v5092062
更新日期:2013-08-28 00:00:00
abstract::Autophagy is an essential vacuolar process of the cell, leading to lysosomal degradation and recycling of proteins and organelles, which is extremely important in maintaining homeostasis. Multiple roles have been now associated with autophagy, in particular a pro-survival role in nutrient starvation or in stressful en...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v9120372
更新日期:2017-12-04 00:00:00
abstract::We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection p...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v6010201
更新日期:2014-01-14 00:00:00
abstract::Diagnostic electron microscopy for infectious diseases has the advantage that "everything" in the specimen can be observed, without a priori knowledge of the likely identity of the microorganisms present in the sample. The classical specimen preparation method used employs a droplet of sample, which allows particles t...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v6093458
更新日期:2014-09-19 00:00:00
abstract::H1N1 swine influenza viruses (SIV) are prevalent in pigs globally, and occasionally emerge in humans, which raises concern about their pandemic threats. To stimulate hemagglutination (HA) of A/Swine/Guangdong/LM/2004 (H1N1) (SW/GD/04) antibody response, eukaryotic expression plasmid pCI-neo-HA was constructed and used...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v9080209
更新日期:2017-08-08 00:00:00
abstract::Type-I interferons (IFN-I) play an important role in the innate immune response to several retroviruses. They seem to be effective in controlling the in vivo infection, though many of the clinical signs of retroviral infection may be due to their continual presence which over-stimulates the immune system and activates...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v1030545
更新日期:2009-12-01 00:00:00
abstract::RNA viruses are extraordinary evolution machines that efficiently ensure their replication by taking advantage of the association with viral and cellular components to form ribonucleic complexes (vRNPs) [...]. ...
journal_title:Viruses
pub_type: 社论
doi:10.3390/v12121355
更新日期:2020-11-26 00:00:00
abstract::Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates with lipid and lipoprotein metabolism disorders such as hepatic steatosis, hypobetalipoproteinemia, and hypocholesterolemia. Furthermore,...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v5051292
更新日期:2013-05-23 00:00:00
abstract::A Chikungunya virus (CHIKV) outbreak in Italy in 2007 spread to include the islands of the Caribbean and most of the Americas and still circulates in Europe and Africa. Florida being close in distance to the Caribbean islands experienced a CHIKV outbreak in 2014 and continues to have a few travel-related cases each ye...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12080823
更新日期:2020-07-29 00:00:00
abstract::Campylobacter jejuni is a frequent foodborne pathogen of humans. As C. jejuni infections commonly arise from contaminated poultry, phage treatments have been proposed to reduce the C. jejuni load on farms to prevent human infections. While a prior report documented the transcriptome of C. jejuni phages during the carr...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v10060332
更新日期:2018-06-16 00:00:00
abstract::An outbreak of winter dysentery, complicated by severe respiratory syndrome, occurred in January 2020 in a high production dairy cow herd located in a hilly area of the Calabria region. Of the 52 animals belonging to the farm, 5 (9.6%) died with severe respiratory distress, death occurring 3-4 days after the appearanc...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12111331
更新日期:2020-11-19 00:00:00
abstract::Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid selection of the v...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12050546
更新日期:2020-05-15 00:00:00
abstract::Environmental and agricultural pollination services by honey bees, Apis mellifera, and honey production are compromised by high levels of annual colony losses globally. The majority are associated with disease caused by deformed wing virus (DWV), a positive-strand RNA virus, exacerbated by the ectoparasitic mite Varro...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12050532
更新日期:2020-05-12 00:00:00
abstract::RNA virus invasion induces a cytosolic RIG-I-like receptor (RLR) signaling pathway by promoting assembly of the Mitochondrial antiviral-signaling protein (MAVS) signalosome and triggers the rapid production of type I interferons (IFNs) and proinflammatory cytokines. During this process, the pivotal kinase TANK binding...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11020158
更新日期:2019-02-15 00:00:00
abstract::Peste des Petits Ruminants (PPR) is a highly infectious disease caused by a virus of the Morbillivirus genus. The current PPR eradication effort relies mainly on the implementation of massive vaccination campaigns. One of the most widely used PPR vaccines is the Nigeria 75/1 strain obtained after attenuation by 75 ser...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11080724
更新日期:2019-08-07 00:00:00
abstract::Streptococcus thermophilus is considered one of the most important species for the dairy industry. Due to their diffusion in dairy environments, bacteriophages can represent a threat to this widely used bacterial species. Despite the presence of a CRISPR-Cas system in the S. thermophilus genome, some lysogenic strains...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11010007
更新日期:2018-12-22 00:00:00
abstract::With the inclusion of new members, understanding about evolutionary mechanisms and processes by which members of the proposed order, Megavirales, have evolved has become a key area of interest. The central role of gene acquisition has been shown in previous studies. However, the major drawback in gene acquisition stud...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v9040072
更新日期:2017-04-07 00:00:00
abstract::Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantaviru...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v6020524
更新日期:2014-02-05 00:00:00
abstract::Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral responses. Since bats experimentally infected with MERS-CoV do not develop ...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11020152
更新日期:2019-02-13 00:00:00
abstract::Bats are an important source of viral zoonoses, including paramyxoviruses. The paramyxoviral Pararubulavirus genus contains viruses mostly derived from bats that are common, diverse, distributed throughout the Old World, and known to be zoonotic. Here, we describe a new member of the genus Achimota pararubulavirus 3 (...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12111236
更新日期:2020-10-30 00:00:00
abstract::Viral outbreaks of varying frequencies and severities have caused panic and havoc across the globe throughout history. Influenza, small pox, measles, and yellow fever reverberated for centuries, causing huge burden for economies. The twenty-first century witnessed the most pathogenic and contagious virus outbreaks of ...
journal_title:Viruses
pub_type: 杂志文章,评审
doi:10.3390/v12040465
更新日期:2020-04-20 00:00:00
abstract::Hepatitis B surface antigen (HBsAg) promotes persistent hepatitis B virus (HBV) infection. It primarily corresponds to small (S) envelope protein secreted as subviral particles. We previously found that genotype D clones expressed less S protein than genotype A clones but showed higher extracellular/intracellular rati...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v12090967
更新日期:2020-09-01 00:00:00
abstract::A field study was undertaken to (i) measure the prevalence of feline leukaemia virus (FeLV) exposure and FeLV infection in a cross-section of healthy Australian pet cats; and (ii) investigate the outcomes following natural FeLV exposure in two Australian rescue facilities. Group 1 (n = 440) consisted of healthy client...
journal_title:Viruses
pub_type: 杂志文章
doi:10.3390/v11060503
更新日期:2019-05-31 00:00:00