Special Issue "Function and Structure of Viral Ribonucleoproteins Complexes".

abstract：:We are currently facing a pandemic of COVID-19, caused by a spillover from an animal-originating coronavirus to humans occurring in the Wuhan region of China in December 2019. From China, the virus has spread to 188 countries and regions worldwide, reaching the Sahel region on March 2, 2020. Since whole genome sequenc...

journal_title：Viruses

authors： Kouriba B,Dürr A,Rehn A,Sangaré AK,Traoré BY,Bestehorn-Willmann MS,Ouedraogo J,Heitzer A,Sogodogo E,Maiga A,Walter MC,Zimmermann F,Wölfel R,Antwerpen MH

更新日期：2020-11-02 00:00:00

abstract：:Rabies is a highly fatal zoonotic disease which is primarily caused by rabies virus (RABV) although other members of the genus Lyssavirus can cause rabies as well. As yet, 14 serologically and genetically diverse lyssaviruses have been identified, mostly in bats. To assess the quality of rabies vaccines and immunoglob...

journal_title：Viruses

authors： Moeschler S,Locher S,Conzelmann KK,Krämer B,Zimmer G

更新日期：2016-09-16 00:00:00

abstract：:Emerging evidence highlights a critical role for protein acetylation during herpesvirus infection. As prominent modulators of protein acetylation, histone deacetylases (HDACs) are essential transcriptional and epigenetic regulators. Not surprisingly, viruses have evolved a wide array of mechanisms to subvert HDAC func...

journal_title：Viruses

authors： Guise AJ,Budayeva HG,Diner BA,Cristea IM

更新日期：2013-06-27 00:00:00

abstract：:RNA virus invasion induces a cytosolic RIG-I-like receptor (RLR) signaling pathway by promoting assembly of the Mitochondrial antiviral-signaling protein (MAVS) signalosome and triggers the rapid production of type I interferons (IFNs) and proinflammatory cytokines. During this process, the pivotal kinase TANK binding...

journal_title：Viruses

authors： He TS,Xie T,Li J,Yang YX,Li C,Wang W,Cao L,Rao H,Ju C,Xu LG

更新日期：2019-02-15 00:00:00

abstract：:Via virome sequencing, six viruses were detected from Magnaporthe oryzae strains YC81-2, including one virus in the family Tombusviridae, one virus in the family Narnaviridae and four viruses in the family Botourmiaviridae. Since the RNA-dependent RNA polymerase (RdRp) of one botourmiavirus show the highest identity (...

journal_title：Viruses

authors： Liu Y,Zhang L,Esmael A,Duan J,Bian X,Jia J,Xie J,Cheng J,Fu Y,Jiang D,Lin Y

更新日期：2020-12-03 00:00:00

abstract：:A lytic bacteriophage PHB01 specific for Pasteurella multocida type D was isolated from the sewage water collected from a pig farm. This phage had the typical morphology of the family Podoviridae, order Caudovirales, presenting an isometric polyhedral head and a short noncontractile tail. PHB01 was able to infect most...

journal_title：Viruses

authors： Chen Y,Guo G,Sun E,Song J,Yang L,Zhu L,Liang W,Hua L,Peng Z,Tang X,Chen H,Wu B

更新日期：2019-01-21 00:00:00

abstract：BACKGROUND:Retroviruses rely on host factors for cell entry, replication, transcription, and other major steps during their life cycle. Human Immunodeficiency Virus-1 (HIV-1) is well known for utilizing a plethora of strategies to evade the host immune response, including the establishment of latent infection within a ...

journal_title：Viruses

authors： Vemula SV,Veerasamy R,Ragupathy V,Biswas S,Devadas K,Hewlett I

更新日期：2015-02-05 00:00:00

abstract：:With the availability of an increasing number of 3D structures of bacteriophage components, combined with powerful in silico predictive tools, it has become possible to decipher the structural assembly and functionality of phage adhesion devices. In the current study, we examined 113 members of the 936 group of lactoc...

journal_title：Viruses

authors： Hayes S,Mahony J,Vincentelli R,Ramond L,Nauta A,van Sinderen D,Cambillau C

更新日期：2019-07-09 00:00:00

abstract：:Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. HuNoV infections lead to substantial societal and economic burdens. There are currently no licensed vaccines or therapeutics for the prevention or treatment of HuNoVs. A lack of well-characterized in vitro and in vivo infection models h...

journal_title：Viruses

authors： Todd KV,Tripp RA

更新日期：2019-02-12 00:00:00

abstract：:Duck Tembusu virus (DTMUV) is a recently emerging pathogenic flavivirus that has resulted in a huge economic loss in the duck industry. However, no vaccine is currently available to control this pathogen. Consequently, a practical strategy to construct a vaccine against this pathogen should be determined. In this stud...

journal_title：Viruses

authors： Zou Z,Liu Z,Jin M

更新日期：2014-06-20 00:00:00

abstract：:An outbreak of winter dysentery, complicated by severe respiratory syndrome, occurred in January 2020 in a high production dairy cow herd located in a hilly area of the Calabria region. Of the 52 animals belonging to the farm, 5 (9.6%) died with severe respiratory distress, death occurring 3-4 days after the appearanc...

journal_title：Viruses

authors： Amoroso MG,Lucifora G,Degli Uberti B,Serra F,De Luca G,Borriello G,De Domenico A,Brandi S,Cuomo MC,Bove F,Riccardi MG,Galiero G,Fusco G

更新日期：2020-11-19 00:00:00

abstract：:Since 2015, severe hydropericardium-hepatitis syndrome (HHS), caused by a highly pathogenic fowl adenovirus 4 (FAdV-4), emerged in China. In our previous study, the FAdV-4 has been identified as a novel genotype with a unique 1966-bp nucleotide deletion (1966Del) between open reading frame 42 and 43. In this study, th...

journal_title：Viruses

authors： Pan Q,Wang J,Gao Y,Cui H,Liu C,Qi X,Zhang Y,Wang Y,Wang X

更新日期：2018-09-13 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is a major cause of pediatric infection and also causes disease in the elderly and those with underlying respiratory problems. There is no vaccine for HRSV and anti-viral therapeutics are not broadly applicable. To investigate the effect of HRSV biology in children, nasopharyng...

journal_title：Viruses

authors： Aljabr W,Armstrong S,Rickett NY,Pollakis G,Touzelet O,Cloutman-Green E,Matthews DA,Hiscox JA

更新日期：2019-10-10 00:00:00

abstract：:Internal ribosome entry is a key mechanism for viral protein synthesis in a subset of RNA viruses. Cricket paralysis virus (CrPV), a member of Dicistroviridae, has a positive-sense single strand RNA genome that contains two internal ribosome entry sites (IRES), a 5'untranslated region (5'UTR) and intergenic region (IG...

journal_title：Viruses

authors： Khong A,Bonderoff JM,Spriggs RV,Tammpere E,Kerr CH,Jackson TJ,Willis AE,Jan E

更新日期：2016-01-19 00:00:00

abstract：:The subgroup A through E avian sarcoma and leukosis viruses (ASLV(A) through ASLV(E)) are a group of highly related alpharetroviruses that have evolved their envelope glycoproteins to use different receptors to enable efficient virus entry due to host resistance and/or to expand host range. Previously, we demonstrated...

journal_title：Viruses

authors： Munguia A,Federspiel MJ

更新日期：2019-06-05 00:00:00

abstract：:The South African national treatment programme includes nucleoside reverse transcriptase inhibitors (NRTIs) in both first and second line highly active antiretroviral therapy regimens. Mutations in the RNase H domain have been associated with resistance to NRTIs but primarily in HIV-1 subtype B studies. Here, we inves...

journal_title：Viruses

authors： Ngcapu S,Theys K,Libin P,Marconi VC,Sunpath H,Ndung'u T,Gordon ML

更新日期：2017-11-08 00:00:00

abstract：:The Bunyaviridae is a family of arboviruses including both plant- and vertebrate-infecting representatives. The Tospovirus genus accommodates plant-infecting bunyaviruses, which not only replicate in their plant host, but also in their insect thrips vector during persistent propagative transmission. For this reason, t...

journal_title：Viruses

authors： Hedil M,Kormelink R

更新日期：2016-07-23 00:00:00

abstract：:Infectious bursal disease (IBD) is an immunosuppressive, highly contagious, and lethal disease of young chickens caused by IBD virus (IBDV). It results in huge economic loss to the poultry industry worldwide. Infection caused by very virulent IBDV (vvIBDV) strains results in high mortality in young chicken flocks. How...

journal_title：Viruses

authors： Yang B,Yan N,Liu A,Li Y,Chen Z,Gao L,Qi X,Gao Y,Liu C,Zhang Y,Cui H,Li K,Pan Q,Wang Y,Wang X

更新日期：2020-02-23 00:00:00

abstract：:Effects of elevated pCO₂ on Emiliania huxleyi genetic diversity and the viruses that infect E. huxleyi (EhVs) have been investigated in large volume enclosures in a Norwegian fjord. Triplicate enclosures were bubbled with air enriched with CO₂ to 760 ppmv whilst the other three enclosures were bubbled with air at ambi...

journal_title：Viruses

authors： Highfield A,Joint I,Gilbert JA,Crawfurd KJ,Schroeder DC

更新日期：2017-03-08 00:00:00

abstract：:The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. The antigenic volume imposed by persistent and latent viruses exposes the immune ...

journal_title：Viruses

authors： Bellon M,Nicot C

更新日期：2017-10-05 00:00:00

abstract：:Feline immunodeficiency virus (FIV) is a naturally occurring T-cell tropic lentiviral disease of felids with many similarities to HIV/AIDS in humans. Similar to primate lentiviral-host interactions, feline APOBEC3 (A3) has been shown to inhibit FIV infection in a host-specific manner and feline A3 degradation is media...

journal_title：Viruses

authors： Troyer RM,Malmberg JL,Zheng X,Miller C,MacMillan M,Sprague WS,Wood BA,VandeWoude S

更新日期：2019-09-07 00:00:00

abstract：:It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and c...

journal_title：Viruses

authors： Grove J

更新日期：2014-03-19 00:00:00

abstract：:Deoxynucleoside triphosphate (dNTP) molecules are essential for the replication and maintenance of genomic information in both cells and a variety of viral pathogens. While the process of dNTP biosynthesis by cellular enzymes, such as ribonucleotide reductase (RNR) and thymidine kinase (TK), has been extensively inves...

journal_title：Viruses

authors： Coggins SA,Mahboubi B,Schinazi RF,Kim B

更新日期：2020-03-31 00:00:00

abstract：:Viral CD8 T-cell epitopes, represented by viral peptides bound to major histocompatibility complex class-I (MHC-I) glycoproteins, are often identified by "reverse immunology", a strategy not requiring biochemical and structural knowledge of the actual viral protein from which they are derived by antigen processing. In...

journal_title：Viruses

authors： Fink A,Büttner JK,Thomas D,Holtappels R,Reddehase MJ,Lemmermann NA

更新日期：2014-02-14 00:00:00

abstract：:H1N1 swine influenza viruses (SIV) are prevalent in pigs globally, and occasionally emerge in humans, which raises concern about their pandemic threats. To stimulate hemagglutination (HA) of A/Swine/Guangdong/LM/2004 (H1N1) (SW/GD/04) antibody response, eukaryotic expression plasmid pCI-neo-HA was constructed and used...

journal_title：Viruses

authors： Liu Y,Li H,Xue Y,Zhao S,Li C,Qu L,Zhang Y,Liu M

更新日期：2017-08-08 00:00:00

abstract：:Environmental and agricultural pollination services by honey bees, Apis mellifera, and honey production are compromised by high levels of annual colony losses globally. The majority are associated with disease caused by deformed wing virus (DWV), a positive-strand RNA virus, exacerbated by the ectoparasitic mite Varro...

journal_title：Viruses

authors： Gusachenko ON,Woodford L,Balbirnie-Cumming K,Campbell EM,Christie CR,Bowman AS,Evans DJ

更新日期：2020-05-12 00:00:00

abstract：:Autophagy is an essential vacuolar process of the cell, leading to lysosomal degradation and recycling of proteins and organelles, which is extremely important in maintaining homeostasis. Multiple roles have been now associated with autophagy, in particular a pro-survival role in nutrient starvation or in stressful en...

journal_title：Viruses

authors： Lussignol M,Esclatine A

更新日期：2017-12-04 00:00:00

abstract：:Cyclophilins are peptidyl-prolyl cis/trans isomerases important in the proper folding of certain proteins. Mounting evidence supports varied roles of cyclophilins, either positive or negative, in the life cycles of diverse viruses, but the nature and mechanisms of these roles are yet to be defined. The potential for c...

journal_title：Viruses

authors： Frausto SD,Lee E,Tang H

更新日期：2013-07-11 00:00:00

abstract：:The environmental factors that lead to the reactivation of human T cell leukemia virus type-1 (HTLV-I) in latently infected T cells in vivo remain unknown. It has been previously shown that heat shock (HS) is a potent inducer of HTLV-I viral protein expression in long-term cultured cell lines. However, the precise HTL...

journal_title：Viruses

authors： Kunihiro M,Fujii H,Miyagi T,Takahashi Y,Tanaka R,Fukushima T,Ansari AA,Tanaka Y

更新日期：2016-07-11 00:00:00