Abstract:
BACKGROUND:As inadequate pain communication contributes to difficulties in optimizing outcomes of outpatients, we investigated the effect of reinforced education using WeChat App to the opioid titration treatment of cancer-related pain in the outpatient setting. METHODS:We conducted a prospective study to compare reinforced education using Wechat with care as usual from February to December 2019. Patients in the reinforced education group received reinforced education via Wechat, while those in the control group received care as usual. Effect measurements for both groups are carried out with questionnaires at the baseline and 3 days later. Questionnaires include pain intensity (NRS), treatment-related adverse events, cancer-related quality of life (QOL), sleep (PSQI), satisfaction, anxiety (GAD-7) and depression (PHQ-9). Number of patients whose NRS reduced to less than three points in 24 h was the primary outcomes. Secondary outcomes included treatment-related adverse events, cancer-related quality of life, sleep, satisfaction, anxiety and depression. RESULTS:Although there was no significant difference regarding pain intensity (NRS) between the two groups at 72 h, the rate of NRS that reduced to less than three points in 24 h was significantly higher in the Wechat group than in the control group. Patients' satisfaction was significantly higher in the Wechat group than in the control group. There was no significant difference between the two groups regarding the other findings at 72 h, including pain intensity (NRS), cancer-related quality of life (QOL), anxiety (GAD-7), depression (PHQ-9), and sleep (PSQI). However, no significant difference was found between the two groups for constipation, nausea, vomiting, dizziness, somnolence, pruritus, loss of consciousness, and death. CONCLUSIONS:Our results indicated that receiving instructions delivered by Wechat resulted an increased number of patients with good pain control and better satisfaction. The study provided insight into the effectiveness of the reinforced education using a Wechat app delivered by a doctor to outpatients in the titration treatment of cancer-related pain. TRIAL REGISTRATION:This study was registered at chictr.org (Registration number: ChiCTR1900021150 , Date of Registration: January 30, 2019).
journal_name
BMC Cancerjournal_title
BMC cancerauthors
Peng Z,Li L,Chen Y,Feng Z,Fang Xdoi
10.1186/s12885-020-07270-wsubject
Has Abstractpub_date
2020-09-04 00:00:00pages
852issue
1issn
1471-2407pii
10.1186/s12885-020-07270-wjournal_volume
20pub_type
杂志文章相关文献
BMC CANCER文献大全abstract:BACKGROUND:Tumor resistance to chemotherapy may be present at the beginning of treatment, develop during treatment, or become apparent on re-treatment of the patient. The mechanisms involved are usually inferred from experiments with cell lines, as studies in tumor-derived cells are difficult. Studies of human tumors s...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-5-78
更新日期:2005-07-18 00:00:00
abstract:BACKGROUND:Golgi phosphoprotein 3 (GOLPH3) has been identified as an oncoprotein in various human cancers; however, its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. We examined GOLPH3 expression levels and relationship with survival in patients with PDAC to establish the significance of GOLPH3 in the dev...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-571
更新日期:2014-08-07 00:00:00
abstract:BACKGROUND:Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhibit distinct epidemiological, clinical, pathological, and molecular features depending on smoking sta...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-778
更新日期:2014-10-24 00:00:00
abstract:BACKGROUND:"Biomarker-driven targeted therapy," the practice of tailoring patients' treatment to the expression/activity levels of disease-specific genes/proteins, remains challenging. For example, while the anti-ERBB2 monoclonal antibody, trastuzumab, was first developed using well-characterized, diverse in vitro brea...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2232-2
更新日期:2016-03-09 00:00:00
abstract:BACKGROUND:To determine, in a meta-analysis, the diagnostic performance of quantitative diffusion-weighted (DW) MR imaging in patients with breast lesions. METHODS:English and Chinese studies published prior to June 2009 to assess the diagnostic performance of quantitative DWI in patients with breast lesions were revi...
journal_title:BMC cancer
pub_type: 杂志文章,meta分析
doi:10.1186/1471-2407-10-693
更新日期:2010-12-29 00:00:00
abstract:BACKGROUND:The neutrophil-to-lymphocyte ratio (NLR), a simple marker of the systemic inflammatory response in critical care patients, has been suggested as an independent prognostic factor for several solid malignancies. We investigated the utility of pretreatment NLR as a prognosticator in patients who presented with ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2134-3
更新日期:2016-02-16 00:00:00
abstract:BACKGROUND:Sunitinib and pazopanib are extensively used as first-line treatment of metastatic renal cell carcinoma (mRCC). We performed this meta-analysis to assess the anti-tumor effectiveness, toxicity, and total costs of the two drugs among patients with mRCC/advanced RCC (aRCC). MATERIALS AND METHODS:PubMed, Scien...
journal_title:BMC cancer
pub_type: 杂志文章,meta分析
doi:10.1186/s12885-019-5704-3
更新日期:2019-05-23 00:00:00
abstract:BACKGROUND:Ovarian carcinoma is a rarely curable disease, for which new treatment options are required. As agents that block HMG-CoA reductase and the mevalonate pathway, the statin family of drugs are used in the treatment of hypercholesterolemia and have been shown to trigger apoptosis in a tumor-specific manner. Rec...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-103
更新日期:2010-03-18 00:00:00
abstract:BACKGROUND:Computational intelligence methods, including non-linear classification algorithms, can be used in medical research and practice as a decision making tool. This study aimed to evaluate the usefulness of artificial intelligence models for 5-year overall survival prediction in patients with cervical cancer tre...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3806-3
更新日期:2017-12-12 00:00:00
abstract:BACKGROUND:While mathematical models are often used to predict progression of cancer and treatment outcomes, there is still uncertainty over how to best model tumor growth. Seven ordinary differential equation (ODE) models of tumor growth (exponential, Mendelsohn, logistic, linear, surface, Gompertz, and Bertalanffy) h...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2164-x
更新日期:2016-02-26 00:00:00
abstract:BACKGROUND:Human papillomaviruses (HPV) are the aetiological agents of certain benign and malignant tumours of skin and mucosae; the most important of which is cervical cancer. Also, the incidence of ano-genital warts, HPV-anal cancer and oropharyngeal cancers are rising. To help ascertain a useful PCR detection protoc...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-9-440
更新日期:2009-12-15 00:00:00
abstract:BACKGROUND:3,3'-diindolylmethane (DIM) is an acid-catalyzed dimer of idole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables that include broccoli, Brussels sprouts and cabbage. DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agent, namely for the treatment of breast cancer. ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-524
更新日期:2014-07-21 00:00:00
abstract:BACKGROUND:Aberrant spliced isoforms are specifically associated with cancer progression and metastasis. The cytoplasmic adaptor CRKL (v-crk avian sarcoma virus CT10 oncogene homolog-like) is a CRK like proto-oncogene, which encodes a SH2 and SH3 (src homology) domain-containing adaptor protein. CRKL is tightly linked ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5671-8
更新日期:2019-05-27 00:00:00
abstract:BACKGROUND:pressurized intraperitoneal aerosol chemotherapy (PIPAC), with or without electrostatic precipitation (ePIPAC), was recently introduced in the treatment of peritoneal metastases (PM) from ovarian cancer (OC). Preliminary clinical data are promising, but several methodological issues as well the anticancer ef...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5658-5
更新日期:2019-05-07 00:00:00
abstract:BACKGROUND:MicroRNAs (miRNAs) are short, non-coding RNAs (~22 nt) that play important roles in the pathogenesis of human diseases by negatively regulating gene expression. Although miR-196a has been implicated in several other cancers, its role in non-small cell lung cancer (NSCLC) is unknown. The aim of the present st...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-12-348
更新日期:2012-08-09 00:00:00
abstract:BACKGROUND:Alcohol consumption is associated with higher breast cancer risk. While studies suggest a modest association between alcohol intake and mammographic density, few studies have examined the association in racial/ethnic minority populations. METHODS:We assessed dense breast area and total breast area from digi...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1094-3
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The Ras-dependent ERK1/2 MAP kinase signaling pathway plays a central role in cell proliferation control and is frequently activated in human colorectal cancer. Small-molecule inhibitors of MEK1/MEK2 are therefore viewed as attractive drug candidates for the targeted therapy of this malignancy. However, the ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-8-337
更新日期:2008-11-17 00:00:00
abstract:BACKGROUND:To validate the robust predictive values of tumor vascularity and hand-foot-skin reaction (HFSR) in combination treatment of transarterial chemoembolization (TACE) and sorafenib for patients with intermediate hepatocellular carcinoma (HCC), and then select the potential candidates who would survive best from...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5570-z
更新日期:2019-04-30 00:00:00
abstract:BACKGROUND:Preclinical research indicate that vascular disrupting agent (VDA) treatment induces extensive tumor death but also a systemic mobilization of bone marrow derived cells including endothelial progenitor cells (EPC) leading to revascularization and renewed growth within the residual tumor. This study investiga...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2568-7
更新日期:2016-07-26 00:00:00
abstract:BACKGROUND:Limited studies examine the immune landscape in Esophageal Adenocarcinoma (EAC). We aim to identify novel associations, which may inform immunotherapy treatment stratification. METHODS:Three hundred twenty-nine EAC cases were available in Tissue Microarrays (TMA) format. A discovery cohort of 166 EAC cases ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-020-06987-y
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Renal cell carcinoma (RCC) is a seventh ranked malignancy with poor prognosis. RCC is lethal at metastatic stage as it does not respond to conventional systemic treatments, and there is an urgent need to find out promising novel biomarkers for effective treatment. The goal of this study was to evaluate the b...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2775-2
更新日期:2016-09-30 00:00:00
abstract:BACKGROUND:Antiangiogenic therapies are considered promising for the treatment of glioblastoma (GB). The non-collagenous C-terminal globular NC1 domain of type VIII collagen a1 chain, Vastatin, is an endogenous antiangiogenic polypeptide. Sustained enhanced expression of Vastatin was shown to inhibit tumour growth and ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3125-8
更新日期:2017-02-13 00:00:00
abstract::... ...
journal_title:BMC cancer
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12885-019-5669-2
更新日期:2019-05-13 00:00:00
abstract:BACKGROUND:For decades, planar bone scintigraphy has been the standard practice for detection of bone metastases in prostate cancer and has been endorsed by recent oncology/urology guidelines. It is a sensitive method with modest specificity. (18)F-fluoride positron emission tomography/computed tomography has shown imp...
journal_title:BMC cancer
pub_type: 临床试验,杂志文章
doi:10.1186/s12885-016-2047-1
更新日期:2016-01-11 00:00:00
abstract:BACKGROUND:The glycosylphosphatidylinositol-anchored extracellular membrane serine protease prostasin is expressed in normal bladder urothelial cells. Bladder inflammation reduces prostasin expression and a loss of prostasin expression is associated with epithelial-mesenchymal transition (EMT) in human bladder transiti...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-2039-6
更新日期:2015-12-29 00:00:00
abstract:BACKGROUND:Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence...
journal_title:BMC cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12885-017-3400-8
更新日期:2017-06-14 00:00:00
abstract:BACKGROUND:In a recent pilot report, we showed that Smac/DIABLO mRNA is expressed de novo in a subset of cervical cancer patients. We have now expanded this study and analyzed Smac/DIABLO expression in the primary lesions in 109 cervical cancer patients. METHODS:We used immunohistochemistry of formalin-fixed, paraffin...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-6-256
更新日期:2006-10-26 00:00:00
abstract:BACKGROUND:The platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), and neutrophil to lymphocyte ratio (NLR) reflect the systematic inflammatory response, with some evidence revealing that they are associated with poorer survival in patients with gastric cancer. However, the effect of the white blood...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-6213-0
更新日期:2019-11-21 00:00:00
abstract:BACKGROUND:Immune checkpoint inhibitors (ICIs) were approved to have a significant antitumor activity in various tumor types. In practice, some patients do not seem to benefit from ICIs but rather to have accelerating disease. The aim of this study was to evaluate hyperprogression in patients with malignant tumors of d...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5921-9
更新日期:2019-07-17 00:00:00
abstract:BACKGROUND:Previous study reported that resveratrol has anti-tumor activity. In this study, we investigated the involvement of autophagy in the resveratrol-induced apoptotic death of human U251 glioma cells. METHODS:The growth inhibition of U251 cells induced by resveratrol was assessed with methyl thiazolyl tetrazoli...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-9-215
更新日期:2009-06-30 00:00:00