Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial.

abstract：OBJECTIVE:To investigate a reported association between dental disease and risk of coronary heart disease. SETTING:National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN:Prospective cohort study in which participants underwent a standard dental examination at bas...

journal_title：BMJ (Clinical research ed.)

authors： DeStefano F,Anda RF,Kahn HS,Williamson DF,Russell CM

更新日期：1993-03-13 00:00:00

abstract：OBJECTIVE:To assess the extent to which the prevailing model of smoking cessation (that smokers typically prepare their attempts to stop smoking in advance and that doing so increases their chances of success) is correct. DESIGN:Cross sectional household survey. SETTING:England. PARTICIPANTS:918 smokers who reported...

journal_title：BMJ (Clinical research ed.)

authors： West R,Sohal T

更新日期：2006-02-25 00:00:00

abstract：OBJECTIVE:To study the comparative importance of environment and genes in the development of islet cell autoimmunity associated with insulin dependent diabetes mellitus. DESIGN:Population based study of diabetic twins. SETTING:Danish population. SUBJECTS:18 monozygotic and 36 dizygotic twin pairs with one or both pa...

journal_title：BMJ (Clinical research ed.)

authors： Petersen JS,Kyvik KO,Bingley PJ,Gale EA,Green A,Dyrberg T,Beck-Nielsen H

更新日期：1997-05-31 00:00:00

abstract：OBJECTIVE:To determine the relation between mothers' self reported drinking habits before, during, and after pregnancy and infants' mental and motor development at 18 months of age. DESIGN:Follow up study of all singleton live births born to primigravidas living in Dundee and booked into antenatal clinics from 1 May 1...

journal_title：BMJ (Clinical research ed.)

authors： Forrest F,Florey CD,Taylor D,McPherson F,Young JA

更新日期：1991-07-06 00:00:00

abstract：:Objective To determine the attributable risk of community acquired pneumonia on incidence of heart failure throughout the age range of affected patients and severity of the infection.Design Cohort study.Setting Six hospitals and seven emergency departments in Edmonton, Alberta, Canada, 2000-02.Participants 4988 adults...

journal_title：BMJ (Clinical research ed.)

authors： Eurich DT,Marrie TJ,Minhas-Sandhu JK,Majumdar SR

更新日期：2017-02-13 00:00:00

abstract：OBJECTIVE:To assess the association between genotype at the insertion or deletion polymorphism of the angiotensin converting enzyme gene and risk of coronary restenosis after percutaneous coronary intervention. DESIGN:Meta-analysis of studies before July 2001 that reported on these genotypes and risk of coronary reste...

journal_title：BMJ (Clinical research ed.)

authors： Bonnici F,Keavney B,Collins R,Danesh J

更新日期：2002-09-07 00:00:00

abstract：OBJECTIVE:To examine the relation between energy intake in childhood and adult mortality from cancer. STUDY DESIGN:Cohort study. SETTING:16 rural and urban centres in England and Scotland. SUBJECTS:3834 people who took part in Lord Boyd Orr's Carnegie survey of family diet and health in prewar Britain between 1937 a...

journal_title：BMJ (Clinical research ed.)

authors： Frankel S,Gunnell DJ,Peters TJ,Maynard M,Davey Smith G

更新日期：1998-02-14 00:00:00

abstract：:Several viral infections have been reported to result in more severe disease in pregnant than non-pregnant women, but the relative risks have not been well characterised. This has now been done for Lassa fever in a prospective study of 68 pregnant and 79 non-pregnant women who were admitted to hospital in Sierra Leone...

journal_title：BMJ (Clinical research ed.)

authors： Price ME,Fisher-Hoch SP,Craven RB,McCormick JB

更新日期：1988-09-03 00:00:00

abstract：OBJECTIVE:To determine the effects on independence in older people needing rehabilitation in a locality based community hospital compared with care on a ward for elderly people in a district general hospital. DESIGN:Randomised controlled trial. SETTING:Care in a community hospital and district general hospital in Bra...

journal_title：BMJ (Clinical research ed.)

authors： Green J,Young J,Forster A,Mallinder K,Bogle S,Lowson K,Small N

更新日期：2005-08-06 00:00:00

abstract：OBJECTIVE:To study the long term risk of cervical and other cancers after treatment for cervical intraepithelial neoplasia. DESIGN:Retrospective cohort study. SETTING:University Hospital, Helsinki, Finland. PARTICIPANTS:7564 women treated for cervical intraepithelial neoplasia during 1974 and 2001 and followed up th...

journal_title：BMJ (Clinical research ed.)

authors： Kalliala I,Anttila A,Pukkala E,Nieminen P

更新日期：2005-11-19 00:00:00

abstract：OBJECTIVE:To determine if trimethoprim use for urinary tract infection (UTI) is associated with an increased risk of acute kidney injury, hyperkalaemia, or sudden death in the general population. DESIGN:Cohort study. SETTING:UK electronic primary care records from practices contributing to the Clinical Practice Resea...

journal_title：BMJ (Clinical research ed.)

authors： Crellin E,Mansfield KE,Leyrat C,Nitsch D,Douglas IJ,Root A,Williamson E,Smeeth L,Tomlinson LA

更新日期：2018-02-09 00:00:00

abstract：OBJECTIVE:To compare the prevalence of antibody to and proviral DNA of the retrovirus HTLV-I in relatives of 11 British patients with tropical spastic paraparesis who had migrated from Jamaica before they developed symptoms, and to examine factors possibly related to transmission of HTLV-I. DESIGN:Migrant, family stud...

journal_title：BMJ (Clinical research ed.)

authors： Cruickshank JK,Richardson JH,Morgan OS,Porter J,Klenerman P,Knight J,Newell AL,Rudge P,Dalgleish AG

更新日期：1990-02-03 00:00:00

abstract：OBJECTIVES:To investigate the effect of Chlamydia pneumoniae infection on future development of ischaemic heart disease and mortality. DESIGN:Prospective longitudinal study. SETTING:Caerphilly, South Wales. SUBJECTS:Plasma specimens were collected during 1979-83 from 1773 men aged 45-59 years. These were tested for ...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP,Carrington D,Mendall MA,Ballam L,Morris J,Butland BK,Sweetnam PM,Elwood PC

更新日期：1999-04-17 00:00:00

abstract：:According to a London physician, women with epilepsy taking antiepileptic drugs can take combined oral contraceptives (OCs). It is usual to recommend a combined OC preparation containing at least 50 mcg of estrogen (Ovran) from patients taking enzyme-inducing antiepileptic drugs; this can be increased to 60 mcg by ta...

journal_title：BMJ (Clinical research ed.)

authors： O'Brien MD,Gilmour-White S

更新日期：1993-08-21 00:00:00

abstract：OBJECTIVE:To investigate whether breast feeding is related to subsequent risk of breast cancer. DESIGN:Population based case-control study designed primarily to investigate the relation between oral contraceptives and risk of breast cancer; data obtained from questionnaires administered by interviewers, general practi...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1993-07-03 00:00:00

abstract：OBJECTIVES:To assess incidence of and mortality from cancer in hypertensive patients taking atenolol, comparing the findings with two control populations and with hypertensive patients taking other drugs. DESIGN:Retrospective analysis of patients first seen in the Glasgow Blood Pressure Clinic between 1972 and 1990. P...

journal_title：BMJ (Clinical research ed.)

authors： Hole DJ,Hawthorne VM,Isles CG,McGhee SM,Robertson JW,Gillis CR,Wapshaw JA,Lever AF

更新日期：1993-03-06 00:00:00

abstract：OBJECTIVES:To estimate the prevalence and incidence of divorce among US physicians compared with other healthcare professionals, lawyers, and non-healthcare professionals, and to analyze factors associated with divorce among physicians. DESIGN:Retrospective analysis of nationally representative surveys conducted by th...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2015-02-18 00:00:00

abstract：:For the past 18 years there has been a proliferation of European committees, boards, associations, colleges, and working groups set up to promote the harmonisation of specialist training in Europe. It has been taken as read that this objective is desirable. The fact that these bodies have achieved remarkably little is...

journal_title：BMJ (Clinical research ed.)

authors： Brearley S

更新日期：1995-07-29 00:00:00

abstract：OBJECTIVE:To explore genetic and environmental contributions to the influence of parental social class and region of upbringing on adult human fatness. DESIGN:Survey of sample of adults who had been adopted in childhood to relate their body mass index to sociodemographic variables in a series of multiple linear regres...

journal_title：BMJ (Clinical research ed.)

authors： Teasdale TW,Sørensen TI,Stunkard AJ

更新日期：1990-06-23 00:00:00

abstract：OBJECTIVE:To compare ultrasonography with intravenous urography in the investigation of adults with haematuria. DESIGN:Prospective study entailing the examination of all patients with both investigations concurrently. The investigations were performed independently on routine lists by different duty radiologists. Each...

journal_title：BMJ (Clinical research ed.)

authors： Spencer J,Lindsell D,Mastorakou I

更新日期：1990-11-10 00:00:00

abstract：OBJECTIVE:To determine the prevalence of sexually transmitted diseases in patients with normal and abnormal cervical smears. DESIGN:A prospective study of asymptomatic women with normal cervical smears attending their general practitioner and newly referred patients with abnormal smears attending a colposcopy clinic. ...

journal_title：BMJ (Clinical research ed.)

authors： Smith JR,Murdoch J,Carrington D,Frew CE,Dougall AJ,MacKinnon H,Baillie D,Byford DM,Forrest CA,Davis JA

更新日期：1991-01-12 00:00:00

abstract：:To study a range of possible risk factors for HIV among injecting drug user patients attending a clinic in London were interviewed from November 1986 to November 1987. Serum samples were tested for viral markers. Of 116 patients, 101 had shared injecting equipment, 75 on the first occasion of injecting and 76 during t...

journal_title：BMJ (Clinical research ed.)

authors： Hart GJ,Sonnex C,Petherick A,Johnson AM,Feinmann C,Adler MW

更新日期：1989-04-22 00:00:00

abstract：OBJECTIVE:To examine the association between obstetric epidural anaesthesia and subsequent long term problems. DESIGN:Postal questionnaire on health problems after childbirth linked to maternity case note data. SETTING:Maternity hospital in Birmingham. SUBJECTS:11701 women who delivered their most recent child durin...

journal_title：BMJ (Clinical research ed.)

authors： MacArthur C,Lewis M,Knox EG

更新日期：1992-05-16 00:00:00

abstract：:This paper examines the impact of marital status on maternal mortality in the period before and the period after German reunification in the area covered by the former East Germany. Maternal mortality ratio prior to the reunification was stable and declined after reunification. This can be attributed to the adoption ...

journal_title：BMJ (Clinical research ed.)

authors： Razum O,Jahn A,Snow R

更新日期：1999-10-23 00:00:00

abstract：OBJECTIVES:To estimate life expectancy for people with HIV undergoing treatment compared with life expectancy in the general population and to assess the impact on life expectancy of late treatment, defined as CD4 count <200 cells/mm(3) at start of antiretroviral therapy. DESIGN:Cohort study. SETTING:Outpatient HIV c...

journal_title：BMJ (Clinical research ed.)

authors： May M,Gompels M,Delpech V,Porter K,Post F,Johnson M,Dunn D,Palfreeman A,Gilson R,Gazzard B,Hill T,Walsh J,Fisher M,Orkin C,Ainsworth J,Bansi L,Phillips A,Leen C,Nelson M,Anderson J,Sabin C

更新日期：2011-10-11 00:00:00

abstract：OBJECTIVES:To provide insight into factors that contribute to the anxiety reported in a quantitative study of the psychological effect of screening for type 2 diabetes. To explore expectations of and reactions to the screening experience of patients with positive, negative, and intermediate results. DESIGN:Prospective...

journal_title：BMJ (Clinical research ed.)

authors： Eborall H,Davies R,Kinmonth AL,Griffin S,Lawton J

更新日期：2007-09-08 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVE:To compare health behaviours during pregnancy (smoking and alcohol consumption) and after birth (initiation and duration of breast feeding) between British/Irish white mothers and mothers from ethnic minority groups; and, in mothers from ethnic minority groups, to examine whether indicators of acculturation (...

journal_title：BMJ (Clinical research ed.)

authors： Hawkins SS,Lamb K,Cole TJ,Law C,Millennium Cohort Study Child Health Group.

更新日期：2008-05-10 00:00:00

abstract：OBJECTIVE:To analyse the relation between treated blood pressure and concomitant risk factor and morbidity from acute myocardial infarction. DESIGN:Prospective longitudinal study. Treated blood pressures and other variables were used to predict acute myocardial infarction. SETTING:Primary health care in Skaraborg, Sw...

journal_title：BMJ (Clinical research ed.)

authors： Lindblad U,Råstam L,Rydén L,Ranstam J,Isacsson SO,Berglund G

更新日期：1994-03-12 00:00:00

abstract：:I have attempted to adopt the perspective of a patient--albeit one with a rather atypical background--to explore what I want from health research and researchers. This has left me with the impression that health researchers could serve the interests of the public more effectively in a variety of ways, and that they wo...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I

更新日期：1995-05-20 00:00:00