Investigation of long term problems after obstetric epidural anaesthesia.

abstract：OBJECTIVE:To assess the effect of weight loss induced by a very low energy diet on moderate and severe obstructive sleep apnoea in obese men. Design Single centre, two arm, parallel, randomised, controlled, open label trial. Blocked randomisation procedure used for treatment allocation. Setting Outpatient obesity clini...

journal_title：BMJ (Clinical research ed.)

authors： Johansson K,Neovius M,Lagerros YT,Harlid R,Rössner S,Granath F,Hemmingsson E

更新日期：2009-12-03 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00

abstract：OBJECTIVE:To investigate the psychosocial factors associated with consultation for low back pain. DESIGN:Two phase cross sectional postal survey. SETTING:Bradford Metropolitan Health District. SUBJECTS:1813 adults responding to the phase 1 questionnaire. 540 of the 782 with an episode of low back pain in the past 12...

journal_title：BMJ (Clinical research ed.)

authors： Waxman R,Tennant A,Helliwell P

更新日期：1998-12-05 00:00:00

abstract：OBJECTIVE:To compare blood pressure control, satisfaction, and adherence to drug treatment in patients with treated hypertension followed up by their family physicians either every three months or every six months for three years. DESIGN:Randomised equivalence clinical trial. Settings 50 family practices in south east...

journal_title：BMJ (Clinical research ed.)

authors： Birtwhistle RV,Godwin MS,Delva MD,Casson RI,Lam M,MacDonald SE,Seguin R,Rühland L

更新日期：2004-01-24 00:00:00

abstract：OBJECTIVES:To investigate use of commodes and attitudes of users and carers to them. DESIGN:Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. SUBJECTS:140 users of a commode and 105 of their carers. RESULTS:Main reasons for being supplied with a co...

journal_title：BMJ (Clinical research ed.)

authors： Naylor JR,Mulley GP

更新日期：1993-11-13 00:00:00

abstract：OBJECTIVE:To explore the suitability of a screening based intervention for excessive alcohol use by describing the experiences of general practitioners who tried such an intervention in their everyday practice. DESIGN:Qualitative interviews with general practitioners who had participated in a pragmatic study of a comb...

journal_title：BMJ (Clinical research ed.)

authors： Beich A,Gannik D,Malterud K

更新日期：2002-10-19 00:00:00

abstract：:According to a London physician, women with epilepsy taking antiepileptic drugs can take combined oral contraceptives (OCs). It is usual to recommend a combined OC preparation containing at least 50 mcg of estrogen (Ovran) from patients taking enzyme-inducing antiepileptic drugs; this can be increased to 60 mcg by ta...

journal_title：BMJ (Clinical research ed.)

authors： O'Brien MD,Gilmour-White S

更新日期：1993-08-21 00:00:00

abstract：OBJECTIVE:To determine the prevalence of diabetes in relation to birth weight in Pima Indians. DESIGN:Follow up study of infants born during 1940-72 who had undergone a glucose tolerance test at ages 20-39 years. SETTING:Gila River Indian community, Arizona. SUBJECTS:1179 American Indians. MAIN OUTCOME MEASURE:Prev...

journal_title：BMJ (Clinical research ed.)

authors： McCance DR,Pettitt DJ,Hanson RL,Jacobsson LT,Knowler WC,Bennett PH

更新日期：1994-04-09 00:00:00

abstract：:The "four principles plus scope" approach provides a simple, accessible, and culturally neutral approach to thinking about ethical issues in health care. The approach, developed in the United States, is based on four common, basic prima facie moral commitments--respect for autonomy, beneficence, nonmaleficence, and ju...

journal_title：BMJ (Clinical research ed.)

authors： Gillon R

更新日期：1994-07-16 00:00:00

abstract：OBJECTIVE:To identify additional factors, such as maternal age or factors related to previous reproductive outcome or family history, and the corresponding probability of carrying a chromosome abnormality in couples with two or more miscarriages. DESIGN:Nested case-control study. SETTING:Six centres for clinical gene...

journal_title：BMJ (Clinical research ed.)

authors： Franssen MT,Korevaar JC,Leschot NJ,Bossuyt PM,Knegt AC,Gerssen-Schoorl KB,Wouters CH,Hansson KB,Hochstenbach R,Madan K,van der Veen F,Goddijn M

更新日期：2005-07-16 00:00:00

abstract：OBJECTIVE:To determine the association of resting echocardiography before elective intermediate to high risk non-cardiac surgery with survival and length of hospital stay. DESIGN:Population based retrospective cohort study. SETTING:Acute care hospitals in Ontario, Canada, between 1 April 1999 and 31 March 2008. PART...

journal_title：BMJ (Clinical research ed.)

authors： Wijeysundera DN,Beattie WS,Karkouti K,Neuman MD,Austin PC,Laupacis A

更新日期：2011-06-30 00:00:00

abstract：:I have attempted to adopt the perspective of a patient--albeit one with a rather atypical background--to explore what I want from health research and researchers. This has left me with the impression that health researchers could serve the interests of the public more effectively in a variety of ways, and that they wo...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I

更新日期：1995-05-20 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：OBJECTIVE:To determine which treatments for preventing coronary heart disease should be offered to which patients by assessing their incremental cost effectiveness. DESIGN:Modelling study. DATA SOURCES:Cost estimates (for NHS) and estimates of effectiveness obtained for aspirin, antihypertensive drugs, statins and cl...

journal_title：BMJ (Clinical research ed.)

authors： Marshall T

更新日期：2003-11-29 00:00:00

abstract：OBJECTIVE:To determine the risk of chronic kidney disease in patients with psoriasis. DESIGN:Population based cohort study and nested cross sectional study. SETTING:Electronic medical records database based in United Kingdom. PARTICIPANTS:Cohort study: patients with psoriasis aged 18-90 each matched to up to five pa...

journal_title：BMJ (Clinical research ed.)

authors： Wan J,Wang S,Haynes K,Denburg MR,Shin DB,Gelfand JM

更新日期：2013-10-15 00:00:00

abstract：:Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate. Hepatorenal syndrome is diagnosed when kidney function is reduced but evidence of intrinsic kidney disease, such as hematuria, proteinu...

journal_title：BMJ (Clinical research ed.)

authors： Simonetto DA,Gines P,Kamath PS

更新日期：2020-09-14 00:00:00

abstract：OBJECTIVE:To quantify the association between exposure to higher temperatures and the risk of myocardial infarction at an hourly temporal resolution. DESIGN:Case-crossover study. SETTING:England and Wales Myocardial Ischaemia National Audit Project (MINAP) database. PARTICIPANTS:24,861 hospital admissions for myocar...

journal_title：BMJ (Clinical research ed.)

authors： Bhaskaran K,Armstrong B,Hajat S,Haines A,Wilkinson P,Smeeth L

更新日期：2012-12-13 00:00:00

abstract：:Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome (HHS) are life threatening complications that occur in patients with diabetes. In addition to timely identification of the precipitating cause, the first step in acute management of these disorders includes aggressive administration of intravenous fluids wi...

journal_title：BMJ (Clinical research ed.)

authors： Karslioglu French E,Donihi AC,Korytkowski MT

更新日期：2019-05-29 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of different screening strategies for abdominal aortic aneurysm in men, from the perspective of a national health service. SETTING:Screening units at regional hospitals. PARTICIPANTS:Hypothetical cohort of 65 year old men from the general population. MAIN OUTCOME MEASURES:C...

journal_title：BMJ (Clinical research ed.)

authors： Søgaard R,Laustsen J,Lindholt JS

更新日期：2012-07-05 00:00:00

abstract：OBJECTIVE:To compare perinatal outcomes in births of women with versus without a history of bariatric surgery. DESIGN:Population based matched cohort study. SETTING:Swedish national health service. PARTICIPANTS:1,742,702 singleton births identified in the Swedish medical birth register between 1992 and 2009. For eac...

journal_title：BMJ (Clinical research ed.)

authors： Roos N,Neovius M,Cnattingius S,Trolle Lagerros Y,Sääf M,Granath F,Stephansson O

更新日期：2013-11-12 00:00:00

abstract：OBJECTIVE:To explore geographical and sociodemographic factors associated with variation in equity in access to total hip and knee replacement surgery. DESIGN:Combining small area estimates of need and provision to explore equity in access to care. SETTING:English census wards. SUBJECTS:Patients throughout England w...

journal_title：BMJ (Clinical research ed.)

authors： Judge A,Welton NJ,Sandhu J,Ben-Shlomo Y

更新日期：2010-08-11 00:00:00

abstract：OBJECTIVE:To determine if sufficient evidence exists to support the use of magnetic resonance angiography as a means of selecting patients with recently symptomatic high grade carotid stenosis for surgery. DESIGN:Systematic review of published research on the diagnostic performance of magnetic resonance angiography, 1...

journal_title：BMJ (Clinical research ed.)

authors： Westwood ME,Kelly S,Berry E,Bamford JM,Gough MJ,Airey CM,Meaney JF,Davies LM,Cullingworth J,Smith MA

更新日期：2002-01-26 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVE:To assess the potential effects of primary prevention with anticoagulants or aspirin in atrial fibrillation on Swedish population. DESIGN:Analysis of cost effectiveness based on the following assumptions: about 83,000 people have atrial fibrillation in Sweden, of whom 22,000 would be potential candidates for...

journal_title：BMJ (Clinical research ed.)

authors： Gustafsson C,Asplund K,Britton M,Norrving B,Olsson B,Marké LA

更新日期：1992-12-12 00:00:00

abstract：OBJECTIVE:To assess whether causal criteria can be used to find out whether there is support in published research for maintaining that menopause causes depression. DESIGN:Ninety four articles from 30 years of research examining the relation of natural menopause to depression were traced by using Medline and systemati...

journal_title：BMJ (Clinical research ed.)

authors： Nicol-Smith L

更新日期：1996-11-16 00:00:00

abstract：OBJECTIVE:To assess oesophageal Doppler ultrasonography as a convenient means of optimising positive end expiratory pressure for maximal delivery of oxygen to tissues. DESIGN:Measurements of blood flow, arterial oxygen saturation, and cardiac output by thermodilution (when available) at baseline and at 20-30 minutes a...

journal_title：BMJ (Clinical research ed.)

authors： Singer M,Bennett D

更新日期：1989-05-20 00:00:00

abstract：:The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funde...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,clinical adviser,.,Martin R,NIHR Dissemination Centre.

更新日期：2019-08-27 00:00:00

abstract：OBJECTIVES:To estimate life expectancy for people with HIV undergoing treatment compared with life expectancy in the general population and to assess the impact on life expectancy of late treatment, defined as CD4 count <200 cells/mm(3) at start of antiretroviral therapy. DESIGN:Cohort study. SETTING:Outpatient HIV c...

journal_title：BMJ (Clinical research ed.)

authors： May M,Gompels M,Delpech V,Porter K,Post F,Johnson M,Dunn D,Palfreeman A,Gilson R,Gazzard B,Hill T,Walsh J,Fisher M,Orkin C,Ainsworth J,Bansi L,Phillips A,Leen C,Nelson M,Anderson J,Sabin C

更新日期：2011-10-11 00:00:00

abstract：OBJECTIVE:To investigate the effect of overweight on premature mortality and work disability in young and middle aged Finns. DESIGN:Prospective cohort study based on data collected in the multiphasic health examinations by the Social Insurance Institution of Finland from 1966 to 1972 and follow up until 1982. SETTING...

journal_title：BMJ (Clinical research ed.)

authors： Rissanen A,Heliövaara M,Knekt P,Reunanen A,Aromaa A,Maatela J

更新日期：1990-10-13 00:00:00