Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype?

abstract：OBJECTIVE:To discover whether the wartime government evacuation of children from London and other population centres to rural districts was associated with any increase in childhood leukaemia. DESIGN:Observational study of mortality from leukaemia among the childhood population of England and Wales in relation to the ...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,John SM

更新日期：1994-11-05 00:00:00

abstract：:Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome (HHS) are life threatening complications that occur in patients with diabetes. In addition to timely identification of the precipitating cause, the first step in acute management of these disorders includes aggressive administration of intravenous fluids wi...

journal_title：BMJ (Clinical research ed.)

authors： Karslioglu French E,Donihi AC,Korytkowski MT

更新日期：2019-05-29 00:00:00

abstract：OBJECTIVE:To compare incidences of perinatal mortality and severe perinatal morbidity between low risk term pregnancies supervised in primary care by a midwife and high risk pregnancies supervised in secondary care by an obstetrician. DESIGN:Prospective cohort study using aggregated data from a national perinatal regi...

journal_title：BMJ (Clinical research ed.)

authors： Evers AC,Brouwers HA,Hukkelhoven CW,Nikkels PG,Boon J,van Egmond-Linden A,Hillegersberg J,Snuif YS,Sterken-Hooisma S,Bruinse HW,Kwee A

更新日期：2010-11-02 00:00:00

abstract：OBJECTIVE:To compare patient outcomes of restrictive versus liberal blood transfusion strategies in patients with cardiovascular disease not undergoing cardiac surgery. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Randomised controlled trials involving a threshold for red blood cell transfusion in hospita...

journal_title：BMJ (Clinical research ed.)

authors： Docherty AB,O'Donnell R,Brunskill S,Trivella M,Doree C,Holst L,Parker M,Gregersen M,Pinheiro de Almeida J,Walsh TS,Stanworth SJ

更新日期：2016-03-29 00:00:00

abstract：OBJECTIVES:To investigate the perspectives of patients with asthma on the use of an action plan and the implementation of this plan during an asthma attack that culminated in a visit to an emergency department. DESIGN:Qualitative study. SETTING:Tertiary teaching hospital, suburban hospital, and rural hospital. PARTI...

journal_title：BMJ (Clinical research ed.)

authors： Douglass J,Aroni R,Goeman D,Stewart K,Sawyer S,Thien F,Abramson M

更新日期：2002-04-27 00:00:00

abstract：:The results of a survey of 769 patients attending the St. James's University Fertility Control Clinic, England, for abortion services showed that patients seeing general practitioners were less knowledgeable than those attending specialist clinics. There was a demonstrated need for counseling on pill and condom use a...

journal_title：BMJ (Clinical research ed.)

authors： Bromham DR,Cartmill RS

更新日期：1993-02-27 00:00:00

abstract：OBJECTIVE:To investigate the effect of two different food supplements on body mass index (BMI) in wasted Malawian adults with HIV who were starting antiretroviral therapy. DESIGN:Randomised, investigator blinded, controlled trial. SETTING:Large, public clinic associated with a referral hospital in Blantyre, Malawi. ...

journal_title：BMJ (Clinical research ed.)

authors： Ndekha MJ,van Oosterhout JJ,Zijlstra EE,Manary M,Saloojee H,Manary MJ

更新日期：2009-05-22 00:00:00

abstract：OBJECTIVES:To examine the effects of physical work environment on long term sickness absence and to investigate interaction between physical and psychosocial risk factors. DESIGN AND SETTING:Prospective cohort study of long term sickness absence among employees in Denmark. PARTICIPANTS:5357 employees interviewed in 2...

journal_title：BMJ (Clinical research ed.)

authors： Lund T,Labriola M,Christensen KB,Bültmann U,Villadsen E

更新日期：2006-02-25 00:00:00

abstract：OBJECTIVE:To describe the progression of HIV disease in a haemophilic cohort and to show the influence of treatment. DESIGN:11 year longitudinal clinical and laboratory study. SETTING:A haemophilia centre. PATIENTS:111 patients infected with HIV during October 1979 to July 1985. MAIN OUTCOME MEASURES:Symptoms of HI...

journal_title：BMJ (Clinical research ed.)

authors： Lee CA,Phillips AN,Elford J,Janossy G,Griffiths P,Kernoff P

更新日期：1991-11-02 00:00:00

abstract：:Currently, clinicians have to make decisions about how to manage pulmonary embolism on the basis of imperfect tests and assessment of odds. Management protocols that inevitably result in large numbers of patients being referred for angiography are unhelpful. Management decisions based on assessment of odds and investi...

journal_title：BMJ (Clinical research ed.)

authors： Fennerty T

更新日期：1997-02-08 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVE:To determine the prevalence of HIV among pregnant women, in particular those whose behaviour or that of their partners put them at "low risk" of infection. DESIGN:Voluntary named or anonymous HIV testing of pregnant women during 21 months (November 1988 to July 1990). SUBJECTS AND SETTING:All women who plan...

journal_title：BMJ (Clinical research ed.)

authors： Goldberg DJ,MacKinnon H,Smith R,Patel NB,Scrimgeour JB,Inglis JM,Peutherer JF,Urquhart GE,Emslie JA,Covell RG

更新日期：1992-04-25 00:00:00

abstract：OBJECTIVE:To assess the waste of research related to inadequate methods in trials included in Cochrane reviews and to examine to what extent this waste could be avoided. A secondary objective was to perform a simulation study to re-estimate this avoidable waste if all trials were adequately reported. DESIGN:Methodolog...

journal_title：BMJ (Clinical research ed.)

authors： Yordanov Y,Dechartres A,Porcher R,Boutron I,Altman DG,Ravaud P

更新日期：2015-03-24 00:00:00

abstract：OBJECTIVE:To investigate the contribution of neuroleptic drugs to cognitive decline in dementia. DESIGN:Two year prospective, longitudinal study consisting of interviews every four months, with necropsy follow up. SETTING:Community settings in Oxfordshire. SUBJECTS:71 subjects with dementia, initially living at home...

journal_title：BMJ (Clinical research ed.)

authors： McShane R,Keene J,Gedling K,Fairburn C,Jacoby R,Hope T

更新日期：1997-01-25 00:00:00

abstract：OBJECTIVE:To investigate the association between several types of soy products and all cause and cause specific mortality. DESIGN:Population based cohort study. SETTING:Japan Public Health Centre-based Prospective Study, which includes 11 public health centre areas in Japan. PARTICIPANTS:92 915 participants (42 750 ...

journal_title：BMJ (Clinical research ed.)

authors： Katagiri R,Sawada N,Goto A,Yamaji T,Iwasaki M,Noda M,Iso H,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2020-01-29 00:00:00

abstract：OBJECTIVE:To establish the extent of prescribing injectable and oral methadone to opiate addicts and the practice characteristics and dispensing arrangements attached to these prescriptions. DESIGN:National survey of 25% random sample of community (high street) pharmacies through postal questionnaire, with four mailin...

journal_title：BMJ (Clinical research ed.)

authors： Strang J,Sheridan J,Barber N

更新日期：1996-08-03 00:00:00

abstract：:Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. Forces that helped this integration included the desire for change, national developments in education, financial support through funds se...

journal_title：BMJ (Clinical research ed.)

authors： Bain J,Scott R,Snadden D

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of interventions designed to improve outcomes in patients with multimorbidity in primary care and community settings. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled trials, the database of abstracts of review...

journal_title：BMJ (Clinical research ed.)

authors： Smith SM,Soubhi H,Fortin M,Hudon C,O'Dowd T

更新日期：2012-09-03 00:00:00

abstract：OBJECTIVES:To determine whether the dose of vitamin A currently recommended by the World Health Organization or half this dose gives better protection against childhood morbidity and mortality. DESIGN:Randomised study. SETTING:A combined oral polio vaccine and vitamin A supplementation campaign in Guinea-Bissau, Afri...

journal_title：BMJ (Clinical research ed.)

authors： Benn CS,Martins C,Rodrigues A,Jensen H,Lisse IM,Aaby P

更新日期：2005-12-17 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：OBJECTIVE:To investigate socioeconomic variation among young women in the risk of hospital admission for diseases (including neoplasms) of the female genital system and breast and for the common surgical procedures of dilatation and curettage and hysterectomy. DESIGN:Large nationally representative cohort study with i...

journal_title：BMJ (Clinical research ed.)

authors： Kuh D,Stirling S

更新日期：1995-09-30 00:00:00

abstract：:First aid, as a profession in its own right, has a history of only 120 years. It evolved from the teachings of the Royal Humane Society and military surgeons, who saw the wisdom of training in splinting and bandaging for battlefield wounds. In 1878 two Aberdeenshire military officers, Surgeon-Major Peter Shepherd of t...

journal_title：BMJ (Clinical research ed.)

authors： Pearn J

更新日期：1994-12-24 00:00:00

abstract：:For the past 18 years there has been a proliferation of European committees, boards, associations, colleges, and working groups set up to promote the harmonisation of specialist training in Europe. It has been taken as read that this objective is desirable. The fact that these bodies have achieved remarkably little is...

journal_title：BMJ (Clinical research ed.)

authors： Brearley S

更新日期：1995-07-29 00:00:00

abstract：:A study was performed to assess whether the existing differential capitation fees for general practitioners accurately assess differential workloads. Data from the third morbidity study in general practice were used to compare capitation fees with relative workload in differing age and sex groups. The population mix w...

journal_title：BMJ (Clinical research ed.)

authors： Fleming DM

更新日期：1988-10-15 00:00:00

abstract：:Managed care has entered the lexicon of healthcare reform, but confusion and ignorance surround its meaning and purpose. It seeks to cut the costs of health care while maintaining its quality, but the evidence that it is able to achieve these aims is mixed. As well as raising awareness and understanding of the issues ...

journal_title：BMJ (Clinical research ed.)

authors： Fairfield G,Hunter DJ,Mechanic D,Rosleff F

更新日期：1997-06-21 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy in the treatment of patients with fever and neutropenia. DATA SOURCES:Medline, Embase, Lilacs, the Cochrane Library, and conference proceedings to 2002. References of included studies and contact wit...

journal_title：BMJ (Clinical research ed.)

authors： Paul M,Soares-Weiser K,Leibovici L

更新日期：2003-05-24 00:00:00

abstract：OBJECTIVE:To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. DESIGN:Cross sectional multicentre study. SETTING:49 public hospitals in major cities in Argentina, from September 2010 to May 2011. PARTICIPANTS:30,448 mothers (7293 vaccinated) and their 30,76...

journal_title：BMJ (Clinical research ed.)

authors： Rubinstein F,Micone P,Bonotti A,Wainer V,Schwarcz A,Augustovski F,Pichon Riviere A,Karolinski A,EVA Study Research Group Estudio Embarazo y Vacuna Antigripal.

更新日期：2013-02-04 00:00:00

abstract：:Lung cancer, the most prevalent cancer in the Western world, is mainly caused by smoking. Nevertheless, only 20% of smokers develop lung cancer and while prevention is important, environmental factors are expected to contribute to the predicted rise in the incidence of lung cancer in the next 25 years. Survival of lun...

journal_title：BMJ (Clinical research ed.)

authors： Sethi T

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:To prospectively assess the diagnostic performance of simple ultrasound rules to predict benignity/malignancy in an adnexal mass and to test the performance of the risk of malignancy index, two logistic regression models, and subjective assessment of ultrasonic findings by an experienced ultrasound examiner ...

journal_title：BMJ (Clinical research ed.)

authors： Timmerman D,Ameye L,Fischerova D,Epstein E,Melis GB,Guerriero S,Van Holsbeke C,Savelli L,Fruscio R,Lissoni AA,Testa AC,Veldman J,Vergote I,Van Huffel S,Bourne T,Valentin L

更新日期：2010-12-14 00:00:00

abstract：OBJECTIVE:To systematically review the accuracy of physicians' clinical predictions of survival in terminally ill cancer patients. DATA SOURCES:Cochrane Library, Medline (1996-2000), Embase, Current Contents, and Cancerlit databases as well as hand searching. STUDY SELECTION:Studies were included if a physician's tem...

journal_title：BMJ (Clinical research ed.)

authors： Glare P,Virik K,Jones M,Hudson M,Eychmuller S,Simes J,Christakis N

更新日期：2003-07-26 00:00:00