Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality.

abstract：OBJECTIVES:To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN:Screening is offered on the basis of informed consent in response to an information sheet entitled "A new test for baby boys--Do you want it?" The programme includes a prospective long term evaluation of family res...

journal_title：BMJ (Clinical research ed.)

authors： Bradley DM,Parsons EP,Clarke AJ

更新日期：1993-02-06 00:00:00

abstract：OBJECTIVE:To do an indirect comparison analysis of apixaban against dabigatran etexilate (2 doses) and rivaroxaban (1 dose), as well as of rivaroxaban against dabigatranetexilate (2 doses), for their relative efficacy and safety against each other, with particular focus on the secondary prevention population for stroke...

journal_title：BMJ (Clinical research ed.)

authors： Rasmussen LH,Larsen TB,Graungaard T,Skjøth F,Lip GY

更新日期：2012-11-05 00:00:00

abstract：OBJECTIVES:(a) To investigate defensive medical practices among general practitioners; (b) to compare any such practices with general practitioners' understanding of certain aspects of the terms of service and medical negligence and practitioners' concerns about the risk of being sued or having a complaint lodged. DES...

journal_title：BMJ (Clinical research ed.)

authors： Summerton N

更新日期：1995-01-07 00:00:00

abstract：OBJECTIVES:To determine clinical correlates and outcome of hypoxaemia in children admitted to hospital with an acute lower respiratory tract infection. DESIGN:Prospective cohort study. SETTING:Paediatric wards of the Royal Victoria Hospital and the hospital of the Medical Research Council's hospital in Banjul, the Ga...

journal_title：BMJ (Clinical research ed.)

authors： Usen S,Weber M,Mulholland K,Jaffar S,Oparaugo A,Omosigho C,Adegbola R,Greenwood B

更新日期：1999-01-09 00:00:00

abstract：OBJECTIVE:To identify the number of patients who were misdiagnosed as being in the vegetative state and their characteristics. DESIGN:Retrospective study of the clinical records of the medical, occupational therapy, and clinical psychology departments. SETTING:20 bed unit specialising in the rehabilitation of patient...

journal_title：BMJ (Clinical research ed.)

authors： Andrews K,Murphy L,Munday R,Littlewood C

更新日期：1996-07-06 00:00:00

abstract：OBJECTIVE:To investigate the effects of spinal cord stimulation on myocardial ischaemia, coronary blood flow, and myocardial oxygen consumption in angina pectoris induced by atrial pacing. DESIGN:The heart was paced to angina during a control phase and treatment with spinal cord stimulation. Blood samples were drawn f...

journal_title：BMJ (Clinical research ed.)

authors： Mannheimer C,Eliasson T,Andersson B,Bergh CH,Augustinsson LE,Emanuelsson H,Waagstein F

更新日期：1993-08-21 00:00:00

abstract：OBJECTIVE:To examine the extent of uptake of medication for secondary prevention of coronary heart disease in older British men and women before (1998-2001) and after (2003) the implementation of the national service framework. DESIGN:Two population based, longitudinal studies of men and women aged 60-79 in 1998-2001,...

journal_title：BMJ (Clinical research ed.)

authors： Ramsay SE,Whincup PH,Lawlor DA,Papacosta O,Lennon LT,Thomas MC,Ebrahim S,Morris RW

更新日期：2006-01-21 00:00:00

abstract：OBJECTIVE:To develop an evidence base for recommendations on the use of atypical antipsychotics for patients with schizophrenia. DESIGN:Systematic overview and meta-regression analyses of randomised controlled trials, as a basis for formal development of guidelines. SUBJECTS:12 649 patients in 52 randomised trials co...

journal_title：BMJ (Clinical research ed.)

authors： Geddes J,Freemantle N,Harrison P,Bebbington P

更新日期：2000-12-02 00:00:00

abstract：:National allocation of resources to regional health authorities and by them to districts is now determined by a weighted capitation formula. The national formula was derived from regression analysis, with hospital utilisation as an index of need for health care--a method which has fundamental limitations. This paper a...

journal_title：BMJ (Clinical research ed.)

authors： Sheldon TA,Smith GD,Bevan G

更新日期：1993-03-27 00:00:00

abstract：OBJECTIVES:To determine whether fibrinogen and lipid concentrations are risk factors for ischaemic stroke. DESIGN:Case-control study with a population based comparison within the overall study. SETTING:Oxfordshire community stroke project and a neurology clinic. SUBJECTS:105 patients who had a transient ischaemic at...

journal_title：BMJ (Clinical research ed.)

authors： Qizilbash N,Jones L,Warlow C,Mann J

更新日期：1991-09-14 00:00:00

abstract：OBJECTIVE:To assess body shape trajectories in early and middle life in relation to risk of mortality. DESIGN:Prospective cohort study. SETTING:Nurses' Health Study and Health Professionals Follow-up Study. POPULATION:80 266 women and 36 622 men who recalled their body shape at ages 5, 10, 20, 30, and 40 years and p...

journal_title：BMJ (Clinical research ed.)

authors： Song M,Hu FB,Wu K,Must A,Chan AT,Willett WC,Giovannucci EL

更新日期：2016-05-04 00:00:00

abstract：:The International AIDS Vaccine Initiative, based in New York, US, was established in 1996 to develop a safe and affordable AIDS vaccine. It is funded by a number of large foundations and charities, the British government, and the World Bank. The Initiative's first 2 large projects, 2 research programs into a vaccine...

journal_title：BMJ (Clinical research ed.)

authors： Matthews H

更新日期：1998-12-05 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intensive geriatric rehabilitation on demented patients with hip fracture. DESIGN:Preplanned subanalysis of randomised intervention study. Settting: Jyväskylä Central Hospital, Finland. PARTICIPANTS:243 independently living patients aged 65 years or older admitted to hospital with ...

journal_title：BMJ (Clinical research ed.)

authors： Huusko TM,Karppi P,Avikainen V,Kautiainen H,Sulkava R

更新日期：2000-11-04 00:00:00

abstract：OBJECTIVE:To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the intervention or outcome. DESIGN:Combined analysis of data from three meta-epidemiological studies based on collections of meta-an...

journal_title：BMJ (Clinical research ed.)

authors： Wood L,Egger M,Gluud LL,Schulz KF,Jüni P,Altman DG,Gluud C,Martin RM,Wood AJ,Sterne JA

更新日期：2008-03-15 00:00:00

abstract：OBJECTIVE:To determine whether abnormal results for liver function tests are investigated in primary care and findings on full investigation. DESIGN:Retrospective audit and prospective clinical investigation. SETTING:University hospital and surrounding general practices serving around 330 000 people. SUBJECTS:Adults...

journal_title：BMJ (Clinical research ed.)

authors： Sherwood P,Lyburn I,Brown S,Ryder S

更新日期：2001-02-03 00:00:00

abstract：OBJECTIVE:To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. DESIGN:Cross sectional multicentre study. SETTING:49 public hospitals in major cities in Argentina, from September 2010 to May 2011. PARTICIPANTS:30,448 mothers (7293 vaccinated) and their 30,76...

journal_title：BMJ (Clinical research ed.)

authors： Rubinstein F,Micone P,Bonotti A,Wainer V,Schwarcz A,Augustovski F,Pichon Riviere A,Karolinski A,EVA Study Research Group Estudio Embarazo y Vacuna Antigripal.

更新日期：2013-02-04 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of day hospital attendance in prolonging independent living for elderly people. DESIGN:Systematic review of 12 controlled clinical trials (available by January 1997) comparing day hospital care with comprehensive care (five trials), domiciliary care (four trials), or no comprehen...

journal_title：BMJ (Clinical research ed.)

authors： Forster A,Young J,Langhorne P

更新日期：1999-03-27 00:00:00

abstract：OBJECTIVE:To explore the hypothesis that different methods of selecting and printing information for cancer patients could improve emotional support by affecting interaction with others, and so lead to improved psychological wellbeing. DESIGN:Randomised trial with eight groups (three factors, 2x2x2). Data collected at...

journal_title：BMJ (Clinical research ed.)

authors： Jones RB,Pearson J,Cawsey AJ,Bental D,Barrett A,White J,White CA,Gilmour WH

更新日期：2006-04-22 00:00:00

abstract：OBJECTIVE:To determine whether a booklet given to patients being discharged from hospital giving details of their admission and treatment increased their knowledge and recall when reviewed in outpatient clinics. DESIGN:Patients alternately allocated to receive a booklet or to serve as controls. Assessment by a questio...

journal_title：BMJ (Clinical research ed.)

authors： Sandler DA,Mitchell JR,Fellows A,Garner ST

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:To assess the effect of the timing of first postnatal home visit by community health workers on neonatal mortality. DESIGN:Analysis of prospectively collected data using time varying discrete hazard models to estimate hazard ratios for neonatal mortality according to day of first postnatal home visit. DATA ...

journal_title：BMJ (Clinical research ed.)

authors： Baqui AH,Ahmed S,El Arifeen S,Darmstadt GL,Rosecrans AM,Mannan I,Rahman SM,Begum N,Mahmud AB,Seraji HR,Williams EK,Winch PJ,Santosham M,Black RE,Projahnmo 1 Study Group.

更新日期：2009-08-14 00:00:00

abstract：OBJECTIVES:Analysis of incidence and characteristics of congenital abdominal wall defects, with special reference to the differences between the incidence of gastroschisis and exomphalos (omphalocele). DESIGN:Retrospective analysis using data from the Office of Population Censuses and Surveys (recoded to differentiate...

journal_title：BMJ (Clinical research ed.)

authors： Tan KH,Kilby MD,Whittle MJ,Beattie BR,Booth IW,Botting BJ

更新日期：1996-10-12 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVES:To examine the risk of atrial fibrillation in relation to the whole spectrum of thyroid function in a large cohort of patients. DESIGN:Population based cohort study of general practice patients identified by linkage of nationwide registries at the individual level. SETTING:Primary care patients in the city...

journal_title：BMJ (Clinical research ed.)

authors： Selmer C,Olesen JB,Hansen ML,Lindhardsen J,Olsen AM,Madsen JC,Faber J,Hansen PR,Pedersen OD,Torp-Pedersen C,Gislason GH

更新日期：2012-11-27 00:00:00

abstract：OBJECTIVE:To obtain information about the computerisation of general practice in Wales, and to enable more effective planning of educational provision for doctors and other primary health care workers. DESIGN:Postal questionnaire sent to all general practices in Wales. SUBJECTS:553 general practices, of which 401 (73...

journal_title：BMJ (Clinical research ed.)

authors： Goves JR,Davies T,Reilly T

更新日期：1991-07-13 00:00:00

abstract：OBJECTIVE:To examine whether the risk of breast cancer is increased by a recent term pregnancy. DESIGN:Population based case-control study. SETTING:Eight areas in the United States. SUBJECTS:Cases were 2279 multiparous women residents of the eight areas aged 25-49 who were diagnosed as having breast cancer during 19...

journal_title：BMJ (Clinical research ed.)

authors： Cummings P,Stanford JL,Daling JR,Weiss NS,McKnight B

更新日期：1994-06-25 00:00:00

abstract：:The aim of community care is to enable people with various types of disability to live in their own homes, rather than in institutions. This involves the provision of support and services at home by various agencies. After a critical report in 1986 identified problems with coordination and flexibility of community car...

journal_title：BMJ (Clinical research ed.)

authors： Renwick D

更新日期：1996-10-05 00:00:00

abstract：OBJECTIVE:To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. DESIGN:Randomised controlled trial. SETTING:30 vascular centres (29 UK, 1 Canadian), 2009-13. ...

journal_title：BMJ (Clinical research ed.)

authors： IMPROVE Trial Investigators.,Powell JT,Sweeting MJ,Thompson MM,Ashleigh R,Bell R,Gomes M,Greenhalgh RM,Grieve R,Heatley F,Hinchliffe RJ,Thompson SG,Ulug P

更新日期：2014-01-13 00:00:00

abstract：OBJECTIVES:To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children. DESIGN:Randomised controlled trial with cluster sampling by general practice. SETTING:General practices in the northern region of the Australian Capital Territory. PARTICIPANTS:174 childre...

journal_title：BMJ (Clinical research ed.)

authors： Glasgow NJ,Ponsonby AL,Yates R,Beilby J,Dugdale P

更新日期：2003-09-20 00:00:00

abstract：OBJECTIVE:To design and evaluate a computer advisory system for the treatment of gestational trophoblastic tumour. DESIGN:A comparison of clinicians' treatment decisions with those of the computer system. Two datasets were used: one to calibrate the system and one to independently evaluate it. SETTING:Department of m...

journal_title：BMJ (Clinical research ed.)

authors： Leaning MS,Gallivan S,Newlands ES,Dent J,Brampton M,Smith DB,Bagshawe KD

更新日期：1992-10-03 00:00:00

abstract：OBJECTIVE:To compare direct and indirect costs of day and inpatient treatment of acute psychiatric illness. DESIGN:Randomised controlled trial with outcome and costs assessed over 12 months after the date of admission. SETTING:Teaching hospital in an inner city area. SUBJECTS:179 patients with acute psychiatric illn...

journal_title：BMJ (Clinical research ed.)

authors： Creed F,Mbaya P,Lancashire S,Tomenson B,Williams B,Holme S

更新日期：1997-05-10 00:00:00