Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality.

abstract：OBJECTIVE:To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. DESIGN:Meta-analysis of randomised trials of oral corticosteroids compared with placebo or a non-steroidal anti-inflammatory...

journal_title：BMJ (Clinical research ed.)

authors： Gøtzsche PC,Johansen HK

更新日期：1998-03-14 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of elective single embryo transfer versus double embryo transfer on the outcomes of live birth, multiple live birth, miscarriage, preterm birth, term singleton birth, and low birth weight after fresh embryo transfer, and on the outcomes of cumulative live birth and multiple live b...

journal_title：BMJ (Clinical research ed.)

authors： McLernon DJ,Harrild K,Bergh C,Davies MJ,de Neubourg D,Dumoulin JC,Gerris J,Kremer JA,Martikainen H,Mol BW,Norman RJ,Thurin-Kjellberg A,Tiitinen A,van Montfoort AP,van Peperstraten AM,Van Royen E,Bhattacharya S

更新日期：2010-12-21 00:00:00

abstract：OBJECTIVE:To establish whether there is evidence of the efficacy of homoeopathy from controlled trials in humans. DESIGN:Criteria based meta-analysis. Assessment of the methodological quality of 107 controlled trials in 96 published reports found after an extensive search. Trials were scored using a list of predefined...

journal_title：BMJ (Clinical research ed.)

authors： Kleijnen J,Knipschild P,ter Riet G

更新日期：1991-02-09 00:00:00

abstract：:The aim of community care is to enable people with various types of disability to live in their own homes, rather than in institutions. This involves the provision of support and services at home by various agencies. After a critical report in 1986 identified problems with coordination and flexibility of community car...

journal_title：BMJ (Clinical research ed.)

authors： Renwick D

更新日期：1996-10-05 00:00:00

abstract：OBJECTIVES:To determine clinical correlates and outcome of hypoxaemia in children admitted to hospital with an acute lower respiratory tract infection. DESIGN:Prospective cohort study. SETTING:Paediatric wards of the Royal Victoria Hospital and the hospital of the Medical Research Council's hospital in Banjul, the Ga...

journal_title：BMJ (Clinical research ed.)

authors： Usen S,Weber M,Mulholland K,Jaffar S,Oparaugo A,Omosigho C,Adegbola R,Greenwood B

更新日期：1999-01-09 00:00:00

abstract：OBJECTIVE:To evaluate the impact of the revised diagnostic criteria for diabetes mellitus adopted by the American Diabetes Association on prevalence of diabetes and on classification of patients. For epidemiological purposes the American criteria use a fasting plasma glucose concentration >=7.0 mmol/l in contrast with ...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1998-08-08 00:00:00

abstract：OBJECTIVE:To examine the predictors of long term outcome for patients with the chronic fatigue syndrome. DESIGN:Cohort study. SUBJECTS:139 subjects previously enrolled in two treatment trials; 103 (74%) were reassessed a mean of 3.2 years after start of the trials. SETTING:University hospital referral centre. MAIN ...

journal_title：BMJ (Clinical research ed.)

authors： Wilson A,Hickie I,Lloyd A,Hadzi-Pavlovic D,Boughton C,Dwyer J,Wakefield D

更新日期：1994-03-19 00:00:00

abstract：OBJECTIVE:To review the evidence for ethnic differences in susceptibility to adverse drug reactions (ADRs) to cardiovascular drugs. DESIGN:Systematic review and meta-analysis. DATA SOURCES:We searched Medline and Embase to March 2005. Reference lists of identified articles were hand searched for further relevant arti...

journal_title：BMJ (Clinical research ed.)

authors： McDowell SE,Coleman JJ,Ferner RE

更新日期：2006-05-20 00:00:00

abstract：OBJECTIVE:To systematically review the accuracy of physicians' clinical predictions of survival in terminally ill cancer patients. DATA SOURCES:Cochrane Library, Medline (1996-2000), Embase, Current Contents, and Cancerlit databases as well as hand searching. STUDY SELECTION:Studies were included if a physician's tem...

journal_title：BMJ (Clinical research ed.)

authors： Glare P,Virik K,Jones M,Hudson M,Eychmuller S,Simes J,Christakis N

更新日期：2003-07-26 00:00:00

abstract：OBJECTIVES:To compare outcome and costs of general practitioners, senior house officers, and registrars treating patients who attended accident and emergency department with problems assessed at triage as being of primary care type. DESIGN:Prospective intervention study which was later costed. SETTING:Inner city acci...

journal_title：BMJ (Clinical research ed.)

authors： Dale J,Lang H,Roberts JA,Green J,Glucksman E

更新日期：1996-05-25 00:00:00

abstract：OBJECTIVE:To investigate the differences between skeletal and chronological age and to assess the role of maturity status, anthropometric data, and football related variables in explaining injury statistics in elite schoolboy footballers. DESIGN:Prospective study of injuries in schoolboy footballers according to skele...

journal_title：BMJ (Clinical research ed.)

authors： Johnson A,Doherty PJ,Freemont A

更新日期：2009-02-26 00:00:00

abstract：OBJECTIVE:To assess the association between macrolide antibiotics prescribing during pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity disorder, and autism spectrum disorder in children. DESIGN:Population based cohort study. SETTING:The UK Clinical Practice Research Datalink...

journal_title：BMJ (Clinical research ed.)

authors： Fan H,Gilbert R,O'Callaghan F,Li L

更新日期：2020-02-19 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：OBJECTIVE:To compare neonatal mortality and morbidity in term infants presenting by the breech and delivered vaginally or by caesarean section. DESIGN:Population based comparison of outcomes. Data derived from the St Mary's maternity information system. SETTING:North West Thames Regional Health Authority, 1988-90. S...

journal_title：BMJ (Clinical research ed.)

authors： Thorpe-Beeston JG,Banfield PJ,Saunders NJ

更新日期：1992-09-26 00:00:00

abstract：OBJECTIVES: To provide contemporary estimates of the prevalence of microcephaly in Europe, determine if the diagnosis of microcephaly is consistent across Europe, and evaluate whether changes in prevalence would be detected using the current European surveillance performed by EUROCAT (the European Surveillance of Conge...

journal_title：BMJ (Clinical research ed.)

authors： Morris JK,Rankin J,Garne E,Loane M,Greenlees R,Addor MC,Arriola L,Barisic I,Bergman JE,Csaky-Szunyogh M,Dias C,Draper ES,Gatt M,Khoshnood B,Klungsoyr K,Kurinczuk JJ,Lynch C,McDonnell R,Nelen V,Neville AJ,O'Mahony

更新日期：2016-09-13 00:00:00

abstract：OBJECTIVE:To assess the education and workload of preregistration house officers in the four Thames regions. DESIGN:Postal questionnaire. SETTING:Teaching and non-teaching hospitals in the four Thames regions. PARTICIPANTS:1064 Preregistration house officers. RESULTS:Response rate was 70% (740 replies). Nine per ce...

journal_title：BMJ (Clinical research ed.)

authors： Dent TH,Gillard JH,Aarons EJ,Crimlisk HL,Smyth-Pigott PJ

更新日期：1990-03-17 00:00:00

abstract：OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

journal_title：BMJ (Clinical research ed.)

authors： van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

更新日期：2000-03-18 00:00:00

abstract：OBJECTIVE:To determine whether in a patient with spontaneous pneumothorax the presence or absence of a pleural leak can be shown at the time of manual aspiration by use of a marker gas. Also, to find out if the technique can predict whether manual aspiration will be successful, hence avoiding the need for intercostal t...

journal_title：BMJ (Clinical research ed.)

authors： Seaton D,Yoganathan K,Coady T,Barker R

更新日期：1991-02-02 00:00:00

abstract：OBJECTIVE:To document the relative importance of endogenous sex steroids in modulating the frequency of orgasms, the dominant aspect of sexual behaviour in healthy eugonadal men. DESIGN:Measurement of adrenal and testicular sex steroids in a sample of army recruits and study of their relation to frequency of orgasms a...

journal_title：BMJ (Clinical research ed.)

authors： Mantzoros CS,Georgiadis EI,Trichopoulos D

更新日期：1995-05-20 00:00:00

abstract：OBJECTIVE:To re-evaluate the causal effect of interpregnancy interval on adverse birth outcomes, on the basis that previous studies relying on between mother comparisons may have inadequately adjusted for confounding by maternal risk factors. DESIGN:Retrospective cohort study using conditional logistic regression (mat...

journal_title：BMJ (Clinical research ed.)

authors： Ball SJ,Pereira G,Jacoby P,de Klerk N,Stanley FJ

更新日期：2014-07-23 00:00:00

abstract：OBJECTIVES:To determine the impact on teenage pregnancy of interventions that address the social disadvantage associated with early parenthood and to assess the appropriateness of such interventions for young people in the United Kingdom. DESIGN:Systematic review, including a statistical meta-analysis of controlled tr...

journal_title：BMJ (Clinical research ed.)

authors： Harden A,Brunton G,Fletcher A,Oakley A

更新日期：2009-11-12 00:00:00

abstract：:Medical audit has its critics, who point to the large sums of NHS cash that seem to be disappearing down a medical plughole. These criticisms are recognised by medical audit advisory groups but there are many reasons why the work of these groups has not yet resulted in many publications in journals or bumped up health...

journal_title：BMJ (Clinical research ed.)

authors： Johnson R

更新日期：1994-07-09 00:00:00

abstract：OBJECTIVE:To assess the impact of a pay for performance incentive on quality of care and outcomes among UK patients with hypertension in primary care. DESIGN:Interrupted time series. SETTING:The Health Improvement Network (THIN) database, United Kingdom. PARTICIPANTS:470 725 patients with hypertension diagnosed betw...

journal_title：BMJ (Clinical research ed.)

authors： Serumaga B,Ross-Degnan D,Avery AJ,Elliott RA,Majumdar SR,Zhang F,Soumerai SB

更新日期：2011-01-25 00:00:00

abstract：OBJECTIVE:To investigate the association of enteroviruses with motor neurone disease, also known as amyotrophic lateral sclerosis. DESIGN:Analysis by enterovirus polymerase chain reaction of wax embedded material from spinal cords taken at necropsy from subjects with motor neurone disease and from age and sex matched ...

journal_title：BMJ (Clinical research ed.)

authors： Woodall CJ,Riding MH,Graham DI,Clements GB

更新日期：1994-06-11 00:00:00

abstract：:Accumulating data indicate that modifications in diet may reduce the risk of cancer by as much as one third and possibly by as much as two thirds. On the basis of the existing evidence, however, it is not possible to be certain which cancers are causally related to diet and what proportion of them are due to specific ...

journal_title：BMJ (Clinical research ed.)

authors： Austoker J

更新日期：1994-06-18 00:00:00

abstract：OBJECTIVE:To assess whether using intensive blood pressure targets leads to lower blood pressure in a community population of people with prevalent cerebrovascular disease. DESIGN:Open label randomised controlled trial. SETTING:99 general practices in England, with participants recruited in 2009-11. PARTICIPANTS:Peo...

journal_title：BMJ (Clinical research ed.)

authors： Mant J,McManus RJ,Roalfe A,Fletcher K,Taylor CJ,Martin U,Virdee S,Greenfield S,Hobbs FD

更新日期：2016-02-24 00:00:00

abstract：OBJECTIVE:To determine the risk of chronic kidney disease in patients with psoriasis. DESIGN:Population based cohort study and nested cross sectional study. SETTING:Electronic medical records database based in United Kingdom. PARTICIPANTS:Cohort study: patients with psoriasis aged 18-90 each matched to up to five pa...

journal_title：BMJ (Clinical research ed.)

authors： Wan J,Wang S,Haynes K,Denburg MR,Shin DB,Gelfand JM

更新日期：2013-10-15 00:00:00

abstract：OBJECTIVES:To determine whether fibrinogen and lipid concentrations are risk factors for ischaemic stroke. DESIGN:Case-control study with a population based comparison within the overall study. SETTING:Oxfordshire community stroke project and a neurology clinic. SUBJECTS:105 patients who had a transient ischaemic at...

journal_title：BMJ (Clinical research ed.)

authors： Qizilbash N,Jones L,Warlow C,Mann J

更新日期：1991-09-14 00:00:00

abstract：OBJECTIVES:To examine the concerns of singlehanded general practitioners working in an inner London area and to compare the views of general practitioners in partnerships. DESIGN:Qualitative analysis of semistructured interviews with a random sample of singlehanded general practitioners and a sample of general practit...

journal_title：BMJ (Clinical research ed.)

authors： Green JM

更新日期：1993-09-04 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00