Patients' experiences of screening for type 2 diabetes: prospective qualitative study embedded in the ADDITION (Cambridge) randomised controlled trial.

abstract：OBJECTIVE:To investigate whether users of oral contraceptives and in [corrected] carriers of a hereditary prothrombotic condition (factor V Leiden mutation, protein C, S, or antithrombin deficiency) have an increased risk of cerebral sinus thrombosis. DESIGN:Comparison of a prospective series of cases of cerebral sinu...

journal_title：BMJ (Clinical research ed.)

authors： de Bruijn SF,Stam J,Koopman MM,Vandenbroucke JP

更新日期：1998-02-21 00:00:00

abstract：OBJECTIVE:To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Medline, Embase, CINAHL, British Nursing Index (BNI), and the Cochrane library were searched for medical subject headings and keywords on diabete...

journal_title：BMJ (Clinical research ed.)

authors： Carter P,Gray LJ,Troughton J,Khunti K,Davies MJ

更新日期：2010-08-18 00:00:00

abstract：:Medical audit has its critics, who point to the large sums of NHS cash that seem to be disappearing down a medical plughole. These criticisms are recognised by medical audit advisory groups but there are many reasons why the work of these groups has not yet resulted in many publications in journals or bumped up health...

journal_title：BMJ (Clinical research ed.)

authors： Johnson R

更新日期：1994-07-09 00:00:00

abstract：OBJECTIVE:To evaluate the immunogenicity and reactogenicity of a new triple S recombinant hepatitis B vaccine in a cohort of healthy people in whom currently licensed hepatitis B vaccines had persistently not induced an immune response. DESIGN:Single centre, randomised, double blind, dose-response study. SETTING:Rese...

journal_title：BMJ (Clinical research ed.)

authors： Zuckerman JN,Sabin C,Craig FM,Williams A,Zuckerman AJ

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:To investigate the relations of maternal diet and smoking during pregnancy to placental and birth weights at term. DESIGN:Prospective cohort study. SETTING:District general hospital in the south of England. PARTICIPANTS:693 pregnant nulliparous white women with singleton pregnancies who were selected from ...

journal_title：BMJ (Clinical research ed.)

authors： Mathews F,Yudkin P,Neil A

更新日期：1999-08-07 00:00:00

abstract：OBJECTIVE:To describe and quantify the patients and clinical activities of independent short stay hospitals. DESIGN:Retrospective survey of hospital records for sampled periods of one financial year and comparison with data from 1981 to 1986. SETTING:217 independent hospitals in England and Wales, 1992-3. MAIN OUTCO...

journal_title：BMJ (Clinical research ed.)

authors： Williams BT,Nicholl JP

更新日期：1994-06-25 00:00:00

abstract：OBJECTIVES:To assess whether supplementation with antioxidants, folinic acid, or both improves the psychomotor and language development of children with Down's syndrome. DESIGN:Randomised controlled trial with two by two factorial design. SETTING:Children living in the Midlands, Greater London, and the south west of ...

journal_title：BMJ (Clinical research ed.)

authors： Ellis JM,Tan HK,Gilbert RE,Muller DP,Henley W,Moy R,Pumphrey R,Ani C,Davies S,Edwards V,Green H,Salt A,Logan S

更新日期：2008-03-15 00:00:00

abstract：OBJECTIVE:To find out what inpatients with advanced cancer who are receiving palliative care think about the effect of thromoprophylaxis on overall quality of life. DESIGN:Qualitative study using audiotaping of semistructured interviews. SETTING:Regional cancer centre in Wales. PARTICIPANTS:28 inpatients with advanc...

journal_title：BMJ (Clinical research ed.)

authors： Noble SI,Nelson A,Turner C,Finlay IG

更新日期：2006-03-11 00:00:00

abstract：:With the aim of promoting the informed choice of pregnant women, staff and pregnant women at two urban hospitals were offered leaflets summarising the best available evidence about the effectiveness of routine ultrasonography in early pregnancy. Ultrasonographers doubted the credibility of the evidence and were concer...

journal_title：BMJ (Clinical research ed.)

authors： Oliver S,Rajan L,Turner H,Oakley A,Entwistle V,Watt I,Sheldon TA,Rosser J

更新日期：1996-11-16 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVE:To examine whether, according to the conclusions of a 2000 systematic review with meta-analysis on interventions to prevent pain from propofol injection that provided a research agenda to guide further research on the topic, subsequently published trials were more often optimally blinded, reported on children...

journal_title：BMJ (Clinical research ed.)

authors： Habre C,Tramèr MR,Pöpping DM,Elia N

更新日期：2014-08-26 00:00:00

abstract：OBJECTIVE:To map and assess prognostic models for outcome prediction in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Systematic review. DATA SOURCES:PubMed until November 2018 and hand searched references from eligible articles. ELIGIBILITY CRITERIA FOR STUDY SELECTION:Studies developing, valid...

journal_title：BMJ (Clinical research ed.)

authors： Bellou V,Belbasis L,Konstantinidis AK,Tzoulaki I,Evangelou E

更新日期：2019-10-04 00:00:00

abstract：OBJECTIVE:To test whether a drug review and symptom self management and lifestyle advice intervention by community pharmacists could reduce hospital admissions or mortality in heart failure patients. DESIGN:Randomised controlled trial. SETTING:Home based intervention in heart failure patients. PARTICIPANTS:293 patie...

journal_title：BMJ (Clinical research ed.)

authors： Holland R,Brooksby I,Lenaghan E,Ashton K,Hay L,Smith R,Shepstone L,Lipp A,Daly C,Howe A,Hall R,Harvey I

更新日期：2007-05-26 00:00:00

abstract：:The studySheppard JP, Stevens S, Stevens R, Martin U, Mant J, Hobbs R, McManus R. Benefits and harms of antihypertensive treatment in low-risk patients with mild hypertension.Published on 1 December 2018 JAMA Intern Med 2018;178:1626-34.This project was funded by a grant from the National Institute for Health Research...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Lamont T,Martin R,NIHR Dissemination Centre.

更新日期：2019-02-15 00:00:00

abstract：OBJECTIVE:To describe the association between epithelial cell IgM, which has previously been associated with an increased incidence of loss of renal graft in children, with a novel cutaneous eruption and unexplained native renal disease. DESIGN:Observational study on children with epithelial cell antibody presenting w...

journal_title：BMJ (Clinical research ed.)

authors： Deal JE,Groves RW,Harmer AW,Welsh KI,MacDonald DM,Rigden SP

更新日期：1991-07-20 00:00:00

abstract：OBJECTIVE:To investigate the effects of the home environment on the risk of severe asthma during adolescence. DESIGN:A questionnaire based case-control study drawn from a cross sectional survey of allergic diseases among secondary school pupils in Sheffield in 1991. SUBJECTS:763 children whose parents had reported th...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP,Carey IM

更新日期：1995-10-21 00:00:00

abstract：OBJECTIVES:To compare the clinical and cost effectiveness of total hip arthroplasty with resurfacing arthroplasty in patients with severe arthritis of the hip. DESIGN:Single centre, two arm, parallel group, assessor blinded, randomised controlled trial with 1:1 treatment allocation. SETTING:One large teaching hospita...

journal_title：BMJ (Clinical research ed.)

authors： Costa ML,Achten J,Parsons NR,Edlin RP,Foguet P,Prakash U,Griffin DR,Young Adult Hip Arthroplasty Team.

更新日期：2012-04-19 00:00:00

abstract：OBJECTIVE:To investigate the association between cerebral palsy and direct evidence for perinatal exposure to neurotropic viruses. DESIGN:Population based case-control study. SETTING:Adelaide Women's and Children's Hospital Research Laboratory. PARTICIPANTS AND MAIN OUTCOME MEASURES:Newborn screening cards of 443 wh...

journal_title：BMJ (Clinical research ed.)

authors： Gibson CS,MacLennan AH,Goldwater PN,Haan EA,Priest K,Dekker GA,South Australian Cerebral Palsy Research Group.

更新日期：2006-01-14 00:00:00

abstract：OBJECTIVES:To identify risk factors predisposing to the development of flucloxacillin associated jaundice. DESIGN:Case-control study. Medical records of cases and controls were reviewed and information recorded on standard data collection forms. SETTING:Alfred Hospital recruiting subjects from Melbourne, Sydney, and ...

journal_title：BMJ (Clinical research ed.)

authors： Fairley CK,McNeil JJ,Desmond P,Smallwood R,Young H,Forbes A,Purcell P,Boyd I

更新日期：1993-01-23 00:00:00

abstract：OBJECTIVE:To independently evaluate the impact of the second phase of the Health Foundation's Safer Patients Initiative (SPI2) on a range of patient safety measures. Design A controlled before and after design. Five substudies: survey of staff attitudes; review of case notes from high risk (respiratory) patients in med...

journal_title：BMJ (Clinical research ed.)

authors： Benning A,Dixon-Woods M,Nwulu U,Ghaleb M,Dawson J,Barber N,Franklin BD,Girling A,Hemming K,Carmalt M,Rudge G,Naicker T,Kotecha A,Derrington MC,Lilford R

更新日期：2011-02-03 00:00:00

abstract：OBJECTIVES:To provide a contemporary account of the treatment and outcomes of acute coronary attacks in England and Wales and to identify strategies that might improve the outcome. DESIGN:Two year community and hospital based study in three British health districts. SETTING:Health districts of Brighton (population 28...

journal_title：BMJ (Clinical research ed.)

authors： Norris RM

更新日期：1998-04-04 00:00:00

abstract：:When oxygen concentrators became available on form FP10 in 1985 the Department of Health and Social Security issued clear guidelines for their prescription for long term treatment. Reassessment of those patients prescribed a concentrator in one district showed that 29 out of 61 patients did not fulfil these criteria. ...

journal_title：BMJ (Clinical research ed.)

authors： Walshaw MJ,Lim R,Evans CC,Hind CR

更新日期：1988-10-22 00:00:00

abstract：OBJECTIVES:To estimate the amount spent on specific hospital care by health agencies in 1993-4 and compare it with the resources allocated to patients registered with fundholding practices for the same type of care. To investigate whether fundholding practices and health agencies pay different amounts for inpatient car...

journal_title：BMJ (Clinical research ed.)

authors： Dixon J,Dinwoodie M,Hodson D,Dodd S,Poltorak T,Garrett C,Rice P,Doncaster I,Williams M

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVE:To investigate associations between Apgar scores of 7, 8, and 9 (versus 10) at 1, 5, and 10 minutes, and neonatal mortality and morbidity. DESIGN:Population based cohort study. SETTING:Sweden. PARTICIPANTS:1 551 436 non-malformed live singleton infants, born at term (≥37 weeks' gestation) between 1999 and ...

journal_title：BMJ (Clinical research ed.)

authors： Razaz N,Cnattingius S,Joseph KS

更新日期：2019-05-07 00:00:00

abstract：OBJECTIVES:To compare the effectiveness of an early switch to oral antibiotics with the standard 7 day course of intravenous antibiotics in severe community acquired pneumonia. DESIGN:Multicentre randomised controlled trial. SETTING:Five teaching hospitals and 2 university medical centres in the Netherlands. PARTICI...

journal_title：BMJ (Clinical research ed.)

authors： Oosterheert JJ,Bonten MJ,Schneider MM,Buskens E,Lammers JW,Hustinx WM,Kramer MH,Prins JM,Slee PH,Kaasjager K,Hoepelman AI

更新日期：2006-12-09 00:00:00

abstract：OBJECTIVES:To compare outcome and costs of general practitioners, senior house officers, and registrars treating patients who attended accident and emergency department with problems assessed at triage as being of primary care type. DESIGN:Prospective intervention study which was later costed. SETTING:Inner city acci...

journal_title：BMJ (Clinical research ed.)

authors： Dale J,Lang H,Roberts JA,Green J,Glucksman E

更新日期：1996-05-25 00:00:00

abstract：OBJECTIVE:To determine the prevalence of HIV among pregnant women, in particular those whose behaviour or that of their partners put them at "low risk" of infection. DESIGN:Voluntary named or anonymous HIV testing of pregnant women during 21 months (November 1988 to July 1990). SUBJECTS AND SETTING:All women who plan...

journal_title：BMJ (Clinical research ed.)

authors： Goldberg DJ,MacKinnon H,Smith R,Patel NB,Scrimgeour JB,Inglis JM,Peutherer JF,Urquhart GE,Emslie JA,Covell RG

更新日期：1992-04-25 00:00:00

abstract：OBJECTIVES:To investigate use of commodes and attitudes of users and carers to them. DESIGN:Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. SUBJECTS:140 users of a commode and 105 of their carers. RESULTS:Main reasons for being supplied with a co...

journal_title：BMJ (Clinical research ed.)

authors： Naylor JR,Mulley GP

更新日期：1993-11-13 00:00:00

abstract：:This review summarises the literature on shift work and its relation to insufficient sleep, chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic reviews, with additional narrative reviews and articles used for outlining possible mechanisms by which shift work may cause accidents and adver...

journal_title：BMJ (Clinical research ed.)

authors： Kecklund G,Axelsson J

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate the risks of adverse pregnancy and birth outcomes for treated and untreated bipolar disorder during pregnancy. DESIGN:Population based cohort study using data from national health registers. SETTING:Sweden. PARTICIPANTS:332,137 women with a last menstrual period anytime after 1 July 2005 and...

journal_title：BMJ (Clinical research ed.)

authors： Bodén R,Lundgren M,Brandt L,Reutfors J,Andersen M,Kieler H

更新日期：2012-11-08 00:00:00