Variation of Genes Encoding Tryptophan Catabolites Pathway Enzymes in Stroke.

abstract：:Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by isolated thrombocytopenia defined as platelet count in peripheral blood <100 × 109/L. Hypovitaminosis D is very common in children with autoimmune diseases. To analyze whether hypovitaminosis D is associated with the clinical presentatio...

journal_title：Journal of clinical medicine

authors： Petrovic D,Benzon B,Batinic M,Culic S,Roganovic J,Markic J

更新日期：2019-11-03 00:00:00

abstract：BACKGROUND:A hierarchical symptoms-based diagnostic strategy relying on the presence of five main symptoms (chest pain, acute dyspnea, neurological symptoms, headache, visual impairment) was recently proposed to diagnose patients with hypertensive emergency. However, poor scientific evidence is available about the role...

journal_title：Journal of clinical medicine

authors： Vallelonga F,Carbone F,Benedetto F,Airale L,Totaro S,Leone D,Astarita A,Avenatti E,Maule S,Veglio F,Lupia E,Milan A

更新日期：2020-07-12 00:00:00

abstract：:Tuberculosis (TB) remains a major health issue worldwide. In order to contain TB infections, improved vaccines as well as accurate and reliable diagnostic tools are desirable. Exosomes are employed for the diagnosis of various diseases. At present, research on exosomes in TB is still at the preliminary stage. Recent s...

journal_title：Journal of clinical medicine

authors： Biadglegne F,König B,Rodloff AC,Dorhoi A,Sack U

更新日期：2021-01-04 00:00:00

abstract：:Purpose: This study aimed to evaluate the effects of a child-centered exergaming program and a traditional teacher-led physical activity (PA) program on preschoolers' executive functions and perceived competence. Methods: Sixty children aged 4⁻5 years from an urban childcare center in China completed an 8-week exergam...

journal_title：Journal of clinical medicine

authors： Xiong S,Zhang P,Gao Z

更新日期：2019-04-06 00:00:00

abstract：BACKGROUND:Exocrine pancreatic insufficiency results from the destruction of the pancreatic parenchyma and is diagnosed by using direct or indirect tests, both of which have shortcomings. Chronic pancreatitis is the most frequent cause of this pathology in adults. METHODS:Patients meeting radiological or histological ...

journal_title：Journal of clinical medicine

authors： Diéguez-Castillo C,Jiménez-Luna C,Martín-Ruiz JL,Martínez-Galán J,Prados J,Torres C,González-Ramírez AR,Caba O

更新日期：2020-06-26 00:00:00

abstract：:We investigated the prognostic influence of androgen receptor (AR) on breast cancer. AR status was assessed using immunohistochemistry with tissue microarrays from 395 operable primary breast cancer patients who received curative surgery. The Kaplan-Meier estimator was used to analyze the survival rates and a log-rank...

journal_title：Journal of clinical medicine

authors： Hwang KT,Kim YA,Kim J,Park JH,Choi IS,Hwang KR,Chai YJ,Park JH

更新日期：2020-04-10 00:00:00

abstract：:The aim of this study was to evaluate the ability of a PIPS (photon-induced photoacoustic streaming) Er:YAG laser to reduce the root canal system bacterial count in vivo in comparison to the traditional irrigation technique. The post-operative patients' quality of life (QoL) after endodontic therapy was evaluated thro...

journal_title：Journal of clinical medicine

authors： Mandras N,Pasqualini D,Roana J,Tullio V,Banche G,Gianello E,Bonino F,Cuffini AM,Berutti E,Alovisi M

更新日期：2020-12-02 00:00:00

abstract：:The present Special Issue of Journal of Clinical Medicine includes a series of important papers that aim to further the evidence base of innovative technological advances in the screening and treatment of mental health, and to further our understanding of their implications for mental health care [...]. ...

journal_title：Journal of clinical medicine

authors： Donker T,Kleiboer A

更新日期：2020-09-24 00:00:00

abstract：:We aimed to develop a mathematical model to predict the progression of aortic stenosis (AS) and aortic dilatation (AD) in bicuspid aortic valve patients. Bicuspid AS patients who underwent at least two serial echocardiograms from 2005 to 2017 were enrolled. Mathematical modeling was undertaken to assess (1) the non-li...

journal_title：Journal of clinical medicine

authors： Kim D,Chae D,Shim CY,Cho IJ,Hong GR,Park K,Ha JW

更新日期：2019-08-24 00:00:00

abstract：BACKGROUND:Ghrelin is a 28-amino acid peptide with an orexigenic property, which is predominantly produced by the stomach. Acylated ghrelin is the active form of this hormone. Obestatin is a 23-amino acid peptide which is produced by post-translational modification of a protein precursor that also produces ghrelin. Obe...

journal_title：Journal of clinical medicine

authors： Razzaghy-Azar M,Nourbakhsh M,Pourmoteabed A,Nourbakhsh M,Ilbeigi D,Khosravi M

更新日期：2016-06-23 00:00:00

abstract：:In the last decade, it has been well-established that tumor-infiltrating myeloid cells fuel not only the process of carcinogenesis through cancer-related inflammation mechanisms, but also tumor progression, invasion, and metastasis. In particular, tumor-associated macrophages (TAMs) are the most abundant leucocyte sub...

journal_title：Journal of clinical medicine

authors： Belgiovine C,Digifico E,Anfray C,Ummarino A,Torres Andón F

更新日期：2020-10-08 00:00:00

abstract：:Objective: To determine blood transfusion practices, risk factors, and outcomes associated with the use of blood products in the setting of the acute management of burn patients at the Victorian Adult Burn Service. Background: Patients with burn injuries have variable transfusion requirements, based on a multitude of ...

journal_title：Journal of clinical medicine

authors： Tichil I,Rosenblum S,Paul E,Cleland H

更新日期：2021-01-27 00:00:00

abstract：:Mutations in the protein DJ-1 cause autosomal recessive forms of Parkinson's disease (PD) and oxidized DJ-1 is found in the brains of idiopathic PD individuals. While several functions have been ascribed to DJ-1 (most notably protection from oxidative stress), its contribution to PD pathogenesis is not yet clear. Here...

journal_title：Journal of clinical medicine

authors： Repici M,Giorgini F

更新日期：2019-09-03 00:00:00

abstract：:The diagnosis of hereditary hemorrhagic telangiectasia (HHT) is based on the Curaçao criteria: epistaxis, telangiectases, arteriovenous malformations in internal organs, and family history. Genetically speaking, more than 90% of HHT patients show mutations in ENG or ACVRL1/ALK1 genes, both belonging to the TGF-β/BMP9 ...

journal_title：Journal of clinical medicine

authors： Albiñana V,Cuesta AM,Rojas-P I,Gallardo-Vara E,Recio-Poveda L,Bernabéu C,Botella LM

更新日期：2020-06-06 00:00:00

abstract：:Post-transplant diabetes mellitus (PTDM) is a serious complication in renal transplant recipients. Branched-chain amino acids (BCAAs) are involved in the pathogenesis of insulin resistance. We determined the association of plasma BCAAs with PTDM and included adult renal transplant recipients (≥18 y) with a functioning...

journal_title：Journal of clinical medicine

authors： Osté MCJ,Flores-Guerrero JL,Gruppen EG,Kieneker LM,Connelly MA,Otvos JD,Dullaart RPF,Bakker SJL

更新日期：2020-02-13 00:00:00

abstract：:Limited information is available regarding interstitial lung disease (ILD) in Erdheim⁻Chester disease (ECD), a rare multisystemic non-Langerhans cell histiocytosis. Sixty-two biopsy-confirmed ECD patients were divided into those with no ILD (19.5%), minimal ILD (32%), mild ILD (29%), and moderate/severe ILD (19.5%), b...

journal_title：Journal of clinical medicine

authors： Haroutunian SG,O'Brien KJ,Estrada-Veras JI,Yao J,Boyd LC,Mathur K,Gahl WA,Mirmomen SM,Malayeri AA,Kleiner DE,Jaffe ES,Gochuico BR

更新日期：2018-08-28 00:00:00

abstract：:Surgery, including minimally invasive surgery, and radiotherapy are key modalities in the treatment of gynecological malignancies. The aim of this review is to offer the multidisciplinary care team a comprehensive summary of the intersections of surgery and radiotherapy in the local treatment of gynecological malignan...

journal_title：Journal of clinical medicine

authors： Fabian A,Krug D,Alkatout I

更新日期：2020-12-29 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic immune-mediated disease manifesting as joint inflammation with functional impairment associated with psoriasis. Recently, PsA has emerged as a systemic disease with several comorbidities, such as cardiovascular diseases and metabolic disorders. Apremilast is a targeted synthetic ...

journal_title：Journal of clinical medicine

authors： Gualtierotti R,De Lucia O

更新日期：2019-03-22 00:00:00

abstract：:This study evaluated whether inter-hospital transfer (IHT) after the return of spontaneous circulation (ROSC) was associated with poor neurological outcomes after 6 months in post-cardiac-arrest patients treated with targeted temperature management (TTM). We used data from the Korean Hypothermia Network prospective re...

journal_title：Journal of clinical medicine

authors： Choi YH,Lee DH,Oh JH,Min JH,Jang TC,Kim WY,Jeong WJ,You JS

更新日期：2020-06-24 00:00:00

abstract：:Background: Due to the higher frequency of ischemic stroke in men compared to women, we aimed to determine if gender differences exist regarding periodontal status and several plasma biomarkers in patients with a recent large artery atherosclerosis ischemic stroke (IS). Material and methods: Patients with their first ...

journal_title：Journal of clinical medicine

authors： Stănescu I,Bulboacă AE,Micu IC,Bolboacă SD,Feștilă DG,Bulboacă AC,Bodizs G,Dogaru G,Boarescu PM,Popa-Wagner A,Roman A

更新日期：2020-06-04 00:00:00

abstract：:Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal micr...

journal_title：Journal of clinical medicine

authors： Lupu M,Caruntu A,Boda D,Caruntu C

更新日期：2020-06-25 00:00:00

abstract：:Recurrent high-grade glioma (HGG) remains incurable with inevitable evolution of resistance and high inter-patient heterogeneity in time to progression (TTP). Here, we evaluate if early tumor volume response dynamics can calibrate a mathematical model to predict patient-specific resistance to develop opportunities for...

journal_title：Journal of clinical medicine

authors： Glazar DJ,Grass GD,Arrington JA,Forsyth PA,Raghunand N,Yu HM,Sahebjam S,Enderling H

更新日期：2020-06-27 00:00:00

abstract：INTRODUCTION:Obesity in pregnant women increases the incidence of pregnancy-induced comorbidities and the rate of operative deliveries. PURPOSE OF THE STUDY:As bariatric surgery is the reference method of treatment of obesity, we wanted to evaluate its influence on the course of pregnancy and perinatal outcomes. MATE...

journal_title：Journal of clinical medicine

authors： Różańska-Walędziak A,Walędziak M,Bartnik P,Kacperczyk-Bartnik J,Janik M,Kowalewski P,Kwiatkowski A,Czajkowski K

更新日期：2020-05-02 00:00:00

abstract：:The aim of this systematic review and meta-analysis was to evaluate the clinical performance of tooth-borne partial and full-coverage fixed dental prosthesis fabricated using hybrid polymer and ceramic CAD/CAM materials regarding their biologic, technical and esthetical outcomes. PICOS search strategy was applied usin...

journal_title：Journal of clinical medicine

authors： Al-Haj Husain N,Özcan M,Molinero-Mourelle P,Joda T

更新日期：2020-07-04 00:00:00

abstract：:Haemoglobinopathies are common monogenic disorders with diverse clinical manifestations, partly attributed to the influence of modifier genes. Recent years have seen enormous growth in the amount of genetic data, instigating the need for ranking methods to identify candidate genes with strong modifying effects. Here, ...

journal_title：Journal of clinical medicine

authors： Stephanou C,Tamana S,Minaidou A,Papasavva P,Kleanthous M,Kountouris P

更新日期：2019-11-09 00:00:00

abstract：:Diabetic nephropathy (DN) often develops in patients suffering from type 1 or type 2 diabetes mellitus. DN is characterized by renal injury resulting in proteinuria. Neuropilin-1 (NRP-1) is a single-pass transmembrane receptor protein devoid of enzymatic activity. Its large extracellular tail is structured in several ...

journal_title：Journal of clinical medicine

authors： Bondeva T,Wolf G

更新日期：2015-06-17 00:00:00

abstract：:An increasing number of patients with coronary artery disease are at high operative risk due to advanced age, severe comorbidities, complex coronary anatomy, and reduced ejection fraction. Consequently, these high-risk patients are often offered percutaneous coronary intervention (PCI) as an alternative to coronary ar...

journal_title：Journal of clinical medicine

authors： Johannsen L,Soldat J,Krueger A,Mahabadi AA,Dykun I,Totzeck M,Jánosi RA,Rassaf T,Al-Rashid F

更新日期：2020-10-25 00:00:00

abstract：:Propionibacterium are anaerobic/aero-tolerant rod Gram-positive bacteria, and numerous studies are associated with primary and secondary endodontic infections. The data in the literature on the prevalence of Propionibacterium are conflicting, and there are studies that report conflicting data on the prevalence in prim...

journal_title：Journal of clinical medicine

authors： Dioguardi M,Alovisi M,Crincoli V,Aiuto R,Malagnino G,Quarta C,Laneve E,Sovereto D,Lo Russo L,Troiano G,Lo Muzio L

更新日期：2020-03-09 00:00:00

abstract：OBJECTIVES:Non-alcoholic fatty liver disease (NAFLD) is considered a well-known pathology that is determined without using alcohol and has emerged as a growing public health problem. Lipotoxicity is known to promote hepatocyte death, which, in the context of NAFLD, is termed lipoapoptosis. The severity of NAFLD correla...

journal_title：Journal of clinical medicine

authors： Bourebaba L,Łyczko J,Alicka M,Bourebaba N,Szumny A,Fal AM,Marycz K

更新日期：2020-05-01 00:00:00

abstract：:Fetal exposure to particulate matter (PM) is associated with infant developmental delay likely via neuroinflammation and prefrontal cortex lesions; however, whether air-purifier usage, which can reduce indoor PM levels, is related to infant developmental delay remains unknown. We therefore examined the prospective rel...

journal_title：Journal of clinical medicine

authors： Matsumura K,Hamazaki K,Tsuchida A,Inadera H,The Japan Environment And Children's Study Jecs Group

更新日期：2020-06-19 00:00:00