Abstract:
:Fetal exposure to particulate matter (PM) is associated with infant developmental delay likely via neuroinflammation and prefrontal cortex lesions; however, whether air-purifier usage, which can reduce indoor PM levels, is related to infant developmental delay remains unknown. We therefore examined the prospective relationship between air-purifier usage during pregnancy and infant developmental delay by analyzing 82,441 mother-infant pairs using a simple yes/no questionnaire. Developmental delays at 6 and 12 months were assessed in five areas using the Ages and Stages Questionnaire, Third Edition. A generalized linear mixed model analysis was used to derive adjusted odds ratios (AORs) and 95% confidence intervals (95% CIs) while controlling for 20 covariates. The analysis revealed that air-purifier usage was associated with developmental delays in fine motor (AOR: 0.91, 95% CI: 0.83-0.99) and problem solving (AOR: 0.83, 95% CI: 0.77-0.90) at 6 months and in communication (AOR: 0.86, 95% CI: 0.79-0.93), fine motor (AOR: 0.87, 95% CI: 0.82-0.92), problem solving (AOR: 0.83, 95% CI: 0.77-0.88), and personal-social (AOR: 0.79, 95% CI: 0.72-0.86) at 12 months. In conclusion, a negative association exists between air-purifier usage during pregnancy and infant neurodevelopmental delay that strengthens with time. Our results outline the potential role of air purifiers in inhibiting infant neurodevelopmental delay.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Matsumura K,Hamazaki K,Tsuchida A,Inadera H,The Japan Environment And Children's Study Jecs Groupdoi
10.3390/jcm9061924subject
Has Abstractpub_date
2020-06-19 00:00:00issue
6issn
2077-0383pii
jcm9061924journal_volume
9pub_type
杂志文章abstract:OBJECTIVE:Clinical presentation of patients with mitral paravalvular leakage (PVL) varies from asymptomatic to heart failure related with hemolytic anemia or pulmonary hypertension. We aimed to investigate the structural and functional characteristics of mitral PVL by multimodal imaging and their association with the s...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2021-01-10 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
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journal_title:Journal of clinical medicine
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abstract::Improving transgender people's quality of life (QoL) is the most important goal of gender-affirming care. Prospective changes in affect can influence QoL. We aim to assess the impact of initiating gender-affirming hormonal treatment (HT) on affect. In the European Network for the Investigation of Gender Incongruence (...
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abstract:BACKGROUND:Profiles of amino acid metabolites (AAMs) have been linked to obesity and energy homeostasis. We investigated whether baseline obesity-related AAMs were associated with weight status in the early postoperative period after sleeve gastrectomy. METHODS:In this prospective, single-arm, longitudinal study, 27 b...
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pub_type: 杂志文章
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journal_title:Journal of clinical medicine
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journal_title:Journal of clinical medicine
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doi:10.3390/jcm8010034
更新日期:2019-01-01 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9040964
更新日期:2020-03-31 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-06-08 00:00:00
abstract::The present Special Issue of Journal of Clinical Medicine includes a series of important papers that aim to further the evidence base of innovative technological advances in the screening and treatment of mental health, and to further our understanding of their implications for mental health care [...]. ...
journal_title:Journal of clinical medicine
pub_type: 社论
doi:10.3390/jcm9103075
更新日期:2020-09-24 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9061744
更新日期:2020-06-04 00:00:00
abstract:INTRODUCTION:Arterial hypertension is the most frequent cause for spontaneous intracerebral hemorrhage (sICH) and may also cause left ventricular hypertrophy (LVH). We sought to analyze whether hypertensive sICH etiology is associated with LVH. METHODS:We analyzed consecutive patients with sICH who were admitted to ou...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072148
更新日期:2020-07-08 00:00:00
abstract::Hypothermic machine perfusion (HMP) has been introduced as an alternative to static cold storage (SCS) in kidney transplantation, but its true benefit in the clinical routine remains incompletely understood. The aim of this study was to assess the effect of HMP vs. SCS in kidney transplantation. All kidney transplants...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072311
更新日期:2020-07-21 00:00:00
abstract::Congenital lactic acidosis (CLA) is a rare condition in most instances due to a range of inborn errors of metabolism that result in defective mitochondrial function. Even though the implementation of next generation sequencing has been rapid, the diagnosis rate for this highly heterogeneous allelic condition remains l...
journal_title:Journal of clinical medicine
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更新日期:2019-11-01 00:00:00
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更新日期:2020-09-15 00:00:00
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