Abstract:
:Dilated Cardiomyopathy (DCM) has a straightforward and apparently "simple" definition: a heart muscle disease characterized by left ventricular (LV) or biventricular dilation and systolic dysfunction in the absence of either pressure or volume overload or coronary artery disease sufficient enough to explain the dysfunction [...].
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Merlo M,Cannatà A,Sinagra Gdoi
10.3390/jcm9113385subject
Has Abstractpub_date
2020-10-22 00:00:00issue
11issn
2077-0383pii
jcm9113385journal_volume
9pub_type
社论abstract::The discovery of microbial, immunological or molecular markers in saliva offers unique opportunities, and has caused our view of saliva to change drastically in recent years [...]. ...
journal_title:Journal of clinical medicine
pub_type: 社论
doi:10.3390/jcm9061955
更新日期:2020-06-23 00:00:00
abstract::Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global coronavirus disease 2019 (COVID-19) outbreak. Along with the respiratory tract, the gastrointestinal (GI) tract is one of the main extra-pulmonary targets of SARS-CoV-2 with respect to symptom occurrence and is a potential route fo...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9113630
更新日期:2020-11-11 00:00:00
abstract::The relationship between obesity and asthma exacerbations is still under debate. The aim of our work is to analyse the relationship between obesity and hospital re-admissions in asthmatics. A review was retrospectively performed on all hospital admissions of adult patients due to asthma exacerbation occurring in our h...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010221
更新日期:2020-01-14 00:00:00
abstract::This study aimed to assess the efficacy of canal filling material removal using three different techniques after filling with a Gutta-Percha (GP) cone and calcium silicate-based sealer, by measuring the percentage of volume debris of GP and sealer remaining intracanal with micro computed tomography (micro-CT). The fil...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8070984
更新日期:2019-07-07 00:00:00
abstract::Age-related macular degeneration is the leading cause of blindness in the developed world. Since advanced glycation end products (AGEs) are implicated in the pathogenesis of AMD through various lines of evidence, we investigated the potential of fructosamine-3-kinase (FN3K) in the disruption of retinal AGEs, drusenoid...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9092869
更新日期:2020-09-04 00:00:00
abstract::Noninvasive ventilation (NIV) during exercise has been suggested to sustain higher training intensity but the type of NIV interface, patient-ventilator asynchronies (PVA) or technological limitation of the ventilator may interfere with exercise. We assessed whether these parameters affect endurance exercise capacity i...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041054
更新日期:2020-04-08 00:00:00
abstract::Objective: To determine blood transfusion practices, risk factors, and outcomes associated with the use of blood products in the setting of the acute management of burn patients at the Victorian Adult Burn Service. Background: Patients with burn injuries have variable transfusion requirements, based on a multitude of ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030476
更新日期:2021-01-27 00:00:00
abstract::Nitric oxide (NO) synthesis markers, comprising L-homoarginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), are significantly associated with cardiovascular events and mortality. Being involved in NO pathways, they may be of high importance regulating vascular tone and arterial hypertensi...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9123895
更新日期:2020-11-30 00:00:00
abstract::Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentia...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm8111970
更新日期:2019-11-14 00:00:00
abstract::In the statin era, the incidence of atherosclerotic cardiovascular diseases (ASCVD) in patients with familial hypercholesterolemia (FH) has not been updated. We aimed to determine the incidence of ASCVD in patients with FH-phenotype (FH-P) and to compare it with that of normal low-density lipoprotein cholesterol (LDL-...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8071080
更新日期:2019-07-23 00:00:00
abstract:BACKGROUND:Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month mortality in patients undergoing TAVI. METHODS:We performed a prospecti...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010160
更新日期:2020-01-07 00:00:00
abstract::Community-acquired pneumonia (CAP) remains the first cause of morbidity and mortality worldwide due to infection. Several aspects such as severity and host response are related to its clinical course and outcome. Beyond the acute implications that the infection provokes in the host, pneumonia also has long-term negati...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9020549
更新日期:2020-02-18 00:00:00
abstract::Haemoglobinopathies are common monogenic disorders with diverse clinical manifestations, partly attributed to the influence of modifier genes. Recent years have seen enormous growth in the amount of genetic data, instigating the need for ranking methods to identify candidate genes with strong modifying effects. Here, ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8111927
更新日期:2019-11-09 00:00:00
abstract::Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE-MTDPS1) is a devastating autosomal recessive disorder due to mutations in TYMP, which cause a loss of function of thymidine phosphorylase (TP), nucleoside accumulation in plasma and tissues, and mitochondrial dysfunction. The clinical picture includes progre...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm7110389
更新日期:2018-10-26 00:00:00
abstract::Lung cancer is the second most common malignancy. Unfortunately, despite advances in multimodality therapeutics for the disease, the overall five-year survival rate among newly diagnosed lung cancer patients remains in the range region of 15%. In addition, although immune checkpoint inhibitors are increasingly being i...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm7100303
更新日期:2018-09-25 00:00:00
abstract::Obstructive sleep apnea (OSA) is a chronic and prevalent disorder, strongly associated with cardiovascular disease (CVD). The apnea-hypopnea index (AHI), or respiratory event index (REI), and the oxygen desaturation index (ODI) are the clinical metrics of sleep apnea in terms of diagnosis and severity. However, AHI, o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9082475
更新日期:2020-08-01 00:00:00
abstract::Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of coronavirus disease 2019 (COVID-19), first emerged in Wuhan, China. The clinical manifestations of patients infected with COVID-19 include fever, cough, and dyspnea, up to acute respiratory distress syndrome (ARDS) and acute cardiac inju...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9124057
更新日期:2020-12-15 00:00:00
abstract::The authors wish to make the following corrections to this paper [...]. ...
journal_title:Journal of clinical medicine
pub_type: 已发布勘误
doi:10.3390/jcm8050574
更新日期:2019-04-26 00:00:00
abstract::The aim of this systematic review and meta-analysis was to evaluate the clinical performance of tooth-borne partial and full-coverage fixed dental prosthesis fabricated using hybrid polymer and ceramic CAD/CAM materials regarding their biologic, technical and esthetical outcomes. PICOS search strategy was applied usin...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9072107
更新日期:2020-07-04 00:00:00
abstract::Air composition influences Dry Eye (DE) symptoms as demonstrated by studies that have linked the outdoor environment to DE. However, there is insufficient data on the effect of short-term exposure to indoor environments on DE symptoms. We conducted a prospective experimental research, in which an older building served...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9051316
更新日期:2020-05-02 00:00:00
abstract::Hemophilia is the most common of the severe bleeding disorders and if not properly managed since early infancy can lead to chronic disease and lifelong disabilities. However, it enjoys the most efficacious and safe treatment among the most prevalent monogenic disorders. Hemophilia should be considered in the neonatal ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm6050054
更新日期:2017-05-19 00:00:00
abstract::To analyse the predictive ability and incremental value of left ventricular longitudinal axis strain (LAS) and late gadolinium enhancement (LGE) using standard cardiovascular magnetic resonance (CMR) imaging for the diagnosis and prognosis of severe aortic stenosis (AS) in patients with an indication for aortic valve ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8020165
更新日期:2019-02-01 00:00:00
abstract::Limited information on the effect of antiretroviral treatment (ART) on vascular function in South Africans of African descent living with human immunodeficiency virus (HIV) is available. The relationship between ART, vascular function and cardiovascular risk factors in South Africans of African ancestry with HIV was t...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030392
更新日期:2021-01-20 00:00:00
abstract::C-reactive protein (CRP) and myxovirus resistance protein A (MxA) are associated with bacterial and viral infections, respectively. We conducted a prospective, multicenter, cross-sectional study of adults and children with febrile upper respiratory tract infections (URIs) to evaluate the diagnostic accuracy of a rapid...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm6100094
更新日期:2017-10-07 00:00:00
abstract::A 37 year-old man presented to the Emergency Department (ED) with new onset seizure and fall from standing.[...]. ...
journal_title:Journal of clinical medicine
pub_type:
doi:10.3390/jcm5040046
更新日期:2016-04-12 00:00:00
abstract::Human papillomavirus (HPV) is the most common sexually transmitted disease. Via infection of the basal epithelial cells, HPV causes numerous malignancies and noncancerous cutaneous manifestations. Noncancerous cutaneous manifestations of HPV, including common, plantar, plane, and anogenital warts, are among the most c...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm4050832
更新日期:2015-04-24 00:00:00
abstract::Epistaxis is a common debilitating manifestation in hereditary hemorrhagic telangiectasia (HHT), due to mucocutaneous telangiectases. The epistaxis can be difficult to control despite available treatments. Dysregulated angiogenesis has been shown to be associated with telangiectases formation. Topical propranolol has ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103130
更新日期:2020-09-28 00:00:00
abstract::Thyroid follicular cells, as well as adrenocortical cells, are endowed by an intrinsic heterogeneity regarding their growth potential, in response to various stimuli. This heterogeneity appears to constitute the underlying cause for the focal cell hyperplasia and eventually the formation of thyroid and adrenal nodules...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm7030037
更新日期:2018-02-26 00:00:00
abstract::The purpose of this study was to compare the thickness of all inner and outer macular layers between ocular hypertension (OHT) and early primary open-angle glaucoma (POAG) using spectral domain optical coherence tomography (SD-OCT) 8 × 8 posterior pole algorithm (8 × 8 PPA). Fifty-seven eyes of 57 OHT individuals and ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9051503
更新日期:2020-05-16 00:00:00
abstract::Effective behavior change approaches are necessary to help individuals avoid or mitigate risk factors, engage in behavioral patterns that lead to better health, and consequently, prevent several chronic diseases. Physical inactivity is considered one of the most harmful risk factors for chronic medical conditions, and...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8030295
更新日期:2019-03-01 00:00:00