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History of Inflammatory Bowel Diseases.

Abstract：

:Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentiate the new entity from intestinal tuberculosis. In the 20th century, an intense and prolific therapeutic research prevailed, culminating in the introduction of biological drugs in the clinical setting. Since the beginning of the 21st century, traditional definition criteria have been challenged by holistic criteria in an effort to seek a still unattained cure. Centuries of worldwide efforts on IBD etiology and therapy search have culminated in this novel strategy.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Actis GC,Pellicano R,Fagoonee S,Ribaldone DG

doi

10.3390/jcm8111970

subject

Has Abstract

pub_date

2019-11-14 00:00:00

issue

11

issn

2077-0383

pii

jcm8111970

journal_volume

8

pub_type

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