Correction: Langeskov-Christensen, M., et al. Aerobic Capacity Is Not Associated with Most Cognitive Domains in Patients with Multiple Sclerosis-A Cross-Sectional Investigation. Journal of Clinical Medicine 2018, 7, 272.

abstract：:Von Hippel-Lindau (VHL), is a rare autosomal dominant inherited cancer in which the lack of VHL protein triggers the development of multisystemic tumors such us retinal hemangioblastomas (HB), CNS-HB, and clear cell renal cell carcinoma (ccRCC). ccRCC ranks third in terms of incidence and first in cause of death. Stan...

journal_title：Journal of clinical medicine

authors： Albiñana V,Gallardo-Vara E,de Rojas-P I,Recio-Poveda L,Aguado T,Canto-Cano A,Aguirre DT,Serra MM,González-Peramato P,Martínez-Piñeiro L,Cuesta AM,Botella LM

更新日期：2020-08-25 00:00:00

abstract：:Diabetic nephropathy patients traditionally show significant macroalbuminuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. Epidemiological surveys confirm that chronic kidney disease (CKD) diagnosed by a low glomerular filtration rate (GFR) is more common ...

journal_title：Journal of clinical medicine

authors： Robles NR,Villa J,Gallego RH

更新日期：2015-09-07 00:00:00

abstract：:Potentially malignant oral lesions, mainly leukoplakia, are common. Malignant transformation varies widely, even in the absence of histological features such as dysplasia. Hence, there is a need for novel biomarker-based systems to more accurately predict the risk of cancer progression. The pluripotency transcription ...

journal_title：Journal of clinical medicine

authors： de Vicente JC,Donate-Pérez Del Molino P,Rodrigo JP,Allonca E,Hermida-Prado F,Granda-Díaz R,Rodríguez Santamarta T,García-Pedrero JM

更新日期：2019-10-21 00:00:00

abstract：:Topical application of vascular endothelial growth factor A (VEGFA) inhibitors including Bevacizumab is used for antiangiogenic therapy at the ocular surface. While clinical studies have suggested that this approach is well-tolerated, the effect of the drug on limbal epithelial stem cells has not been studied. In this...

journal_title：Journal of clinical medicine

authors： Notara M,Lentzsch A,Clahsen T,Behboudifard S,Braun G,Cursiefen C

更新日期：2019-11-09 00:00:00

abstract：:Healthcare systems in the developed world are struggling with the demand of emergency room presentations; the study of the factors driving such demand is of fundamental importance. From a database of all emergency medical admissions (66,933 episodes in 36,271 patients) to St James' Hospital, Dublin, Ireland, over 12 y...

journal_title：Journal of clinical medicine

authors： Conway R,Byrne D,O'Riordan D,Silke B

更新日期：2014-10-29 00:00:00

abstract：:Patients with kidney transplantation often have a worse quality of life than the general population. One of the reasons for this, in male patients, is the high prevalence of erectile dysfunction. This is mainly due to the presence of comorbidities, surgery for kidney transplantation, adverse drug effects, psychologica...

journal_title：Journal of clinical medicine

authors： Perri A,Izzo G,Lofaro D,La Vignera S,Brunetti A,Calogero AE,Aversa A

更新日期：2020-06-25 00:00:00

abstract：:Elevated blood pressure (BP) is a major cause of death, yet hypertension commonly goes undetected. Owing to its nature, it is typically asymptomatic until later in its progression when the vessel or organ structure has already been compromised. Therefore, noninvasive and continuous BP measurement methods are needed to...

journal_title：Journal of clinical medicine

authors： Welykholowa K,Hosanee M,Chan G,Cooper R,Kyriacou PA,Zheng D,Allen J,Abbott D,Menon C,Lovell NH,Howard N,Chan WS,Lim K,Fletcher R,Ward R,Elgendi M

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND AND AIMS:Data from clinical trials suggest that biological drugs may improve the outcomes in Crohn's disease (CD) by reducing the need for surgery or hospitalization. The aim of this study is to evaluate the time-trends of the use of biological drugs and other treatments for CD, and its relationship with out...

journal_title：Journal of clinical medicine

authors： Brunet E,Vela E,Melcarne L,Clèries M,Pontes C,Llovet LP,García-Iglesias P,Gallach M,Villòria A,Vergara M,Calvet X

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:Both old age and institutionalization in aged care homes come with a significant risk of developing several long-term mental and neurological disorders, but there has been no definitive meta-analysis of data from studies to determine the pooled estimate of central nervous system (CNS) medicines use in aged c...

journal_title：Journal of clinical medicine

authors： Hasan SS,Zaidi STR,Nirwan JS,Ghori MU,Javid F,Ahmadi K,Babar ZU

更新日期：2019-08-23 00:00:00

abstract：:The abnormal activation of the tryptophan catabolites pathway (TRYCATs) is observed in patients suffering from cerebrovascular disease, including stroke. A previous study confirmed that lower bioavailability of tryptophan for serotonin synthesis was characterized in the patients during the acute stroke phase. Interest...

journal_title：Journal of clinical medicine

authors： Wigner P,Saluk-Bijak J,Synowiec E,Miller E,Sliwinski T,Cichon N,Bijak M

更新日期：2019-12-03 00:00:00

abstract：:Cardiovascular autonomic neuropathy (CAN) is a common complication of diabetes mellitus. Cardiovascular reflex tests (CARTs) are the gold standard in the diagnosis of CAN, but the handgrip test is no longer recommended to be performed. Previously, the inverse association between the presence of hypertension and handgr...

journal_title：Journal of clinical medicine

authors： Kempler M,Hajdú N,Putz Z,Istenes I,Vági O,Békeffy M,Schnabel K,Kempler P,Körei AE

更新日期：2020-10-16 00:00:00

abstract：:The lack of highly effective treatments for fibromyalgia (FM) represents a great challenge for public health. The objective of this parallel, pilot randomized controlled trial (RCT) was two-fold: (1) to analyze the clinical effects of mindfulness plus amygdala and insula retraining (MAIR) compared to a structurally eq...

journal_title：Journal of clinical medicine

authors： Sanabria-Mazo JP,Montero-Marin J,Feliu-Soler A,Gasión V,Navarro-Gil M,Morillo-Sarto H,Colomer-Carbonell A,Borràs X,Tops M,Luciano JV,García-Campayo J

更新日期：2020-10-11 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory disease which affects the body far beyond the skin. Whereas there is solid evidence that chronic skin inflammation in psoriasis drives cardiovascular disease, the impact on renal impairment and acute kidney injury (AKI) is still unclear. We aimed to analyze the impact of p...

journal_title：Journal of clinical medicine

authors： Wild J,Hobohm L,Münzel T,Wenzel P,Steinbrink K,Karbach S,Keller K

更新日期：2020-09-17 00:00:00

abstract：INTRODUCTION:Advances in the acute treatment of myocardial infarction (AMI) substantially reduced in-hospital mortality, but the post-discharge prognosis is still unacceptable. The Managed Care in Acute Myocardial Infarction (MC-AMI) is a program of Poland's National Health Fund that aims at comprehensive post-AMI care...

journal_title：Journal of clinical medicine

authors： Wita K,Kułach A,Sikora J,Fluder J,Nowalany-Kozielska E,Milewski K,Pączek P,Sobocik H,Olender J,Szela L,Kalarus Z,Buszman P,Jankowski P,Gąsior M

更新日期：2020-09-30 00:00:00

abstract：:The aim of this study was to evaluate the ability of a PIPS (photon-induced photoacoustic streaming) Er:YAG laser to reduce the root canal system bacterial count in vivo in comparison to the traditional irrigation technique. The post-operative patients' quality of life (QoL) after endodontic therapy was evaluated thro...

journal_title：Journal of clinical medicine

authors： Mandras N,Pasqualini D,Roana J,Tullio V,Banche G,Gianello E,Bonino F,Cuffini AM,Berutti E,Alovisi M

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Currently, proposed nomograms are mainly based on post-operative histopathology. The purpose of this study was to identify preoperative computed tomography (CT) and clinical information that allow prediction of disease-free (DFS) and overall survival (OS) of patients surgically treated for pancreatic head ca...

journal_title：Journal of clinical medicine

authors： Hwang SH,Kim HY,Lee EJ,Hwang HK,Park MS,Kim MJ,Lee WJ,Chung YE,Kang CM

更新日期：2019-10-21 00:00:00

abstract：:Sex differences among patients with complement-gene-variant-mediated thrombotic microangiopathy (cTMA) are not well established. We examined demographic and clinical data from female and male patients with a history of cTMA enrolled in the Vienna thrombotic microangiopathy (TMA) cohort. Follow-up was three years after...

journal_title：Journal of clinical medicine

authors： Aigner C,Gaggl M,Kain R,Prohászka Z,Garam N,Csuka D,Sunder-Plassmann R,Piggott LC,Haninger-Vacariu N,Schmidt A,Sunder-Plassmann G

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:There are limited data for non-vitamin K antagonist oral anticoagulants (NOACs) impact on outcomes for patients with atrial fibrillation (AF) and valvular heart diseases (VHDs). METHODS:We identified patients with AF and associated Evaluated Heartvalves, Rheumatic or Artificial (EHRA) type 2 VHDs, and who h...

journal_title：Journal of clinical medicine

authors： Moon I,Lee SR,Choi EK,Lee E,Jung JH,Han KD,Cha MJ,Oh S,Lip GYH

更新日期：2019-10-04 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentia...

journal_title：Journal of clinical medicine

authors： Actis GC,Pellicano R,Fagoonee S,Ribaldone DG

更新日期：2019-11-14 00:00:00

abstract：INTRODUCTION:The laparoscopic approach for TME is proven to be non-inferior in oncological outcome compared to open surgery. Anatomical limitations in the male and obese pelvis with resulting pathological shortcomings and high conversion rates were stimuli for alternative approaches. The transanal approach for TME (TaT...

journal_title：Journal of clinical medicine

authors： Dittrich L,Biebl M,Schmuck R,Gül S,Weiss S,Haase O,Knoop M,Alkatout I,Pratschke J,Aigner F

更新日期：2020-12-28 00:00:00

abstract：:Research examining associations between objectively-measured napping time and type 2 diabetes (T2D) is lacking. This study aimed to evaluate daytime napping in relation to T2D and adiposity measures in elderly individuals from the Mediterranean region. A cross-sectional analysis of baseline data from 2190 elderly part...

journal_title：Journal of clinical medicine

authors： Papandreou C,Díaz-López A,Babio N,Martínez-González MA,Bulló M,Corella D,Fitó M,Romaguera D,Vioque J,Alonso-Gómez ÁM,Wärnberg J,Martínez AJ,Serra-Majem L,Estruch R,Fernández-García JC,Lapetra J,Pintó X,Tur JA,Garcia-R

更新日期：2019-07-19 00:00:00

abstract：:Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Da...

journal_title：Journal of clinical medicine

authors： Amiri M,Schneider T,Oelke M,Murgas S,Michel MC

更新日期：2021-01-15 00:00:00

abstract：:Pulmonary hypertension (PH) in patients with heart failure (HF) contributes to a poorer prognosis. However, in those with dilated cardiomyopathy (DCM), the true prevalence and role of PH is unclear. Therefore, this study aimed to analyze the profile of DCM patients at various levels of PH risk, determined via echocard...

journal_title：Journal of clinical medicine

authors： Dziewięcka E,Wiśniowska-Śmiałek S,Karabinowska A,Holcman K,Gliniak M,Winiarczyk M,Karapetyan A,Kaciczak M,Podolec P,Kostkiewicz M,Hlawaty M,Leśniak-Sobelga A,Rubiś P

更新日期：2020-06-01 00:00:00

abstract：:This study aimed to develop a prognosis-predicting model based on [18F]fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and clinicopathologic factors in locally advanced cervical cancer patients treated with concurrent chemoradiotherapy (CCRT). The medical records of 270 locally adv...

journal_title：Journal of clinical medicine

authors： Lee WK,Chong GO,Jeong SY,Lee HJ,Park SH,Ryu JM,Choi YS,Kang S,Koo YJ,Lee DH,Kong E,Lee SW

更新日期：2020-02-05 00:00:00

abstract：:Infected elderly people often present with signs and symptoms that differ from those in younger adults, but data on the association between patient age and presentation of early Lyme borreliosis (LB) are limited. In this study, the association between patient age (18⁻44 years, young vs. 45⁻64 years, middle-aged vs. ≥ ...

journal_title：Journal of clinical medicine

authors： Boršič K,Blagus R,Cerar T,Strle F,Stupica D

更新日期：2018-12-02 00:00:00

abstract：:There is no treatment of choice for irritable bowel syndrome, which affects up to 20% of school-aged children. This cross-sectional study evaluated the difference in the average vitamin D level between subtypes of irritable bowel syndrome, and the relationship between the vitamin D level as well as the severity of irr...

journal_title：Journal of clinical medicine

authors： Cho Y,Lee Y,Choi Y,Jeong S

更新日期：2018-12-01 00:00:00

abstract：:Endoscopic resection has been the standard treatment for intramucosal esophageal cancers (ECs) because of the low risk of lymph node metastases in the lesions. In recent years, endoscopic submucosal dissection (ESD), which can resect large ECs, has been performed. However, the risk of esophageal stricture after ESD is...

journal_title：Journal of clinical medicine

authors： Hikichi T,Nakamura J,Takasumi M,Hashimoto M,Kato T,Kobashi R,Takagi T,Suzuki R,Sugimoto M,Sato Y,Irie H,Okubo Y,Kobayakawa M,Ohira H

更新日期：2020-12-23 00:00:00

abstract：:Background: Patients with pulmonary embolism (PE) may suffer from long-term consequences, including decreased functional capacity. Data on pulmonary rehabilitation (PR) in patients with PE are scarce, and no data on outpatient PR are available so far. Methods: We analyzed data of 22 PE patients who attended outpatient...

journal_title：Journal of clinical medicine

authors： Nopp S,Klok FA,Moik F,Petrovic M,Derka I,Ay C,Zwick RH

更新日期：2020-06-10 00:00:00

abstract：:Acute cardiovascular disease after community-acquired pneumonia is a well-accepted complication for which definitive treatment strategies are lacking. These complications share some common features but have distinct diagnostic and treatment approaches. We therefore undertook an updated systematic review and meta-analy...

journal_title：Journal of clinical medicine

authors： Tralhão A,Póvoa P

更新日期：2020-02-03 00:00:00

abstract：:Eosinophilic granulomatosis with polyangiitis (EGPA) is a type of systemic vasculitis with eosinophilia in the peripheral blood, which is preceded by bronchial asthma or allergic disease. EGPA is pathologically characterized by microangiopathy granulomatosis vasculitis. Vasculitis can be exacerbated and cause central ...

journal_title：Journal of clinical medicine

authors： Isozaki T,Homma T,Sagara H,Kasama T

更新日期：2020-11-30 00:00:00