Clinical Features and Pathogenic Mechanisms of Gastrointestinal Injury in COVID-19.

Abstract:

:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global coronavirus disease 2019 (COVID-19) outbreak. Along with the respiratory tract, the gastrointestinal (GI) tract is one of the main extra-pulmonary targets of SARS-CoV-2 with respect to symptom occurrence and is a potential route for virus transmission, most likely due to the presence of angiotensin-converting enzyme 2. Therefore, understanding the mechanisms of GI injury is crucial for a harmonized therapeutic strategy against COVID-19. This review summarizes the current evidence for the clinical features of and possible pathogenic mechanisms leading to GI injury in COVID-19.

journal_name

J Clin Med

authors

Mitsuyama K,Tsuruta K,Takedatsu H,Yoshioka S,Morita M,Niwa M,Matsumoto S

doi

10.3390/jcm9113630

subject

Has Abstract

pub_date

2020-11-11 00:00:00

issue

11

issn

2077-0383

pii

jcm9113630

journal_volume

9

pub_type

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