Combined proximal tubulopathy, crystal-storing histiocytosis, and cast nephropathy in a patient with light chain multiple myeloma.

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account. METHODS:In this cross-sectional study, ...

journal_title：BMC nephrology

authors： Soares AA,Prates AB,Weinert LS,Veronese FV,de Azevedo MJ,Silveiro SP

更新日期：2013-02-28 00:00:00

abstract：BACKGROUND:Ongoing efforts are focused on shortening ischemia intervals as much as possible during partial nephrectomy to preserve renal function. Off-clamp partial nephrectomy (off-PN) has been a common strategy for to avoid ischemia in small renal tumors. Although studies comparing the advantages between off-PN with ...

journal_title：BMC nephrology

authors： Deng W,Liu X,Hu J,Chen L,Fu B

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Approximately 4-6% of incident end stage renal disease (ESRD) patients in the U.S. recover enough kidney function to discontinue dialysis but there is considerable geographic variation. We undertook this study to investigate whether state-level variations in renal recovery among incident ESRD patients correl...

journal_title：BMC nephrology

authors： Chen Z,Lee BJ,McCulloch CE,Burrows NR,Heung M,Hsu RK,Pavkov ME,Powe NR,Saran R,Shahinian V,Hsu CY,Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5. METHODS:Qualitative interviews were undertaken with parents, patients and professionals to explore their views on content of the proposed online parent information and support (OPIS) w...

journal_title：BMC nephrology

authors： Swallow VM,Hall AG,Carolan I,Santacroce S,Webb NJ,Smith T,Hanif N

更新日期：2014-02-18 00:00:00

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chronic lesions are absent and adequate anti-inflammatory therapy is immediately initiated. CASE PRESENT...

journal_title：BMC nephrology

authors： Ross S,Benz K,Sauerstein K,Amann K,Dötsch J,Dittrich K

更新日期：2012-08-06 00:00:00

abstract：BACKGROUND:Tissue derived biomarkers may offer utility as indicators of accumulated damage. Reduced thickness of retinal neuronal tissue and the vascular choroid have previously been associated with vascular damage and diabetes. We evaluated associations between retinal thickness, retinal microvascular and choroidal me...

journal_title：BMC nephrology

authors： Paterson EN,Ravindran ML,Griffiths K,Le Velly CA,Cardwell CC,McCarter RV,Nicol P,Chhablani JK,Rasheed MA,Vupparaboina KK,MacGillivray TJ,Harbinson M,Maxwell AP,Hogg RE,McKay GJ

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:Urinary albumin can be measured in 24 h or spot samples. The 24 h urinary albumin excretion rate is considered the gold standard, but is cumbersome to collect. Instead, often an overnight sample is collected, and adjusted for dilution. Proxies for 24 h excretion rate have been studied in diabetics, but seldo...

journal_title：BMC nephrology

authors： Fagerstrom P,Sallsten G,Akerstrom M,Haraldsson B,Barregard L

更新日期：2015-01-24 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Recently there has been a progressive loss of specialty related skills for nephrologists. Among the skills we find the kidney biopsy that has a central role in diagnosis of renal parenchymal disease. One of the causes might be the belief that the kidney biopsy should be performed only in larger Centers which...

journal_title：BMC nephrology

authors： Esposito V,Mazzon G,Baiardi P,Torreggiani M,Semeraro L,Catucci D,Colucci M,Mariotto A,Grosjean F,Bovio G,Esposito C

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...

journal_title：BMC nephrology

authors： Diena D,Messina M,De Biase C,Fop F,Scardino E,Rossetti MM,Barreca A,Verri A,Biancone L

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:Anemia is highly prevalent in chronic kidney disease (CKD). Elevated hepcidin concentrations are an important mediator of disordered iron metabolism, a key mechanism underlying anemia of CKD. Vitamin D was recently shown to reduce serum hepcidin concentrations in healthy individuals. We examined whether trea...

journal_title：BMC nephrology

authors： Panwar B,McCann D,Olbina G,Westerman M,Gutiérrez OM

更新日期：2018-02-09 00:00:00

abstract：BACKGROUND:Stage 5 chronic kidney disease (CKD-5) patients on haemodialysis (HD) are at high risk of accidental falls. Previous research has shown that frailty is one of the primary contributors to the increased risk of falling in this clinical population. However, HD patients often present with abnormalities of cardio...

journal_title：BMC nephrology

authors： Zanotto T,Mercer TH,van der Linden ML,Rush R,Traynor JP,Petrie CJ,Doyle A,Chalmers K,Allan N,Shilliday I,Koufaki P

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regulating cytoskeletal arc...

journal_title：BMC nephrology

authors： Huang Z,Zhang L,Chen Y,Zhang H,Yu C,Zhou F,Zhang Z,Jiang L,Li R,Ma J,Li Z,Lai Y,Lin T,Zhao X,Zhang Q,Zhang B,Ye Z,Liu S,Wang W,Liang X,Liao R,Shi W

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathophysiology of diabetic nephropathy and has expanded the potential available therapies. An increasing n...

journal_title：BMC nephrology

authors： De la Cruz-Cano E,Jiménez-González CDC,Morales-García V,Pineda-Pérez C,Tejas-Juárez JG,Rendón-Gandarilla FJ,Jiménez-Morales S,Díaz-Gandarilla JA

更新日期：2019-10-28 00:00:00

abstract：BACKGROUND:The objective of the study was to examine overall anemia management trends in non-dialysis patients with chronic kidney disease (CKD) from 2006 to 2015, and to evaluate the impact of Trial to Reduced Cardiovascular Events with Ananesp Therapy (TREAT)'s study results (October 2009) and the US Food and Drug Ad...

journal_title：BMC nephrology

authors： Park H,Liu X,Henry L,Harman J,Ross EA

更新日期：2018-11-09 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) has been established as a risk for cardiovascular diseases and mortality in hemodialysis patients. Energy intake (EI) is an important nutritional therapy for preventing MetS. We examined the association of self-reported dietary EI with metabolic abnormalities and MetS among hemodial...

journal_title：BMC nephrology

authors： Duong TV,Wong TC,Chen HH,Chen TW,Chen TH,Hsu YH,Peng SJ,Kuo KL,Liu HC,Lin ET,Wang CS,Tseng IH,Feng YW,Chang TY,Su CT,Yang SH

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:Klotho is a transmembrane protein acting as a co-receptor for FGF-23 and thus exerts clinical actions on mineral metabolism. The association of secreted Klotho with outcomes in CKD patients is unclear. This study examined the relation between plasma Klotho and cardiovascular events in dialysis patients, acco...

journal_title：BMC nephrology

authors： Memmos E,Sarafidis P,Pateinakis P,Tsiantoulas A,Faitatzidou D,Giamalis P,Vasilikos V,Papagianni A

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Adherence to phosphate binder treatment is important to prevent high serum phosphate level in chronic dialysis patients. We therefore wanted to investigate patient knowledge, beliefs about and adherence to phosphate binders among these patients and assess whether one-to-one pharmacist-led education and couns...

journal_title：BMC nephrology

authors： Hjemås BJ,Bøvre K,Mathiesen L,Lindstrøm JC,Bjerknes K

更新日期：2019-05-17 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Hypertensive nephropathy (HTN) is a kind of renal injury caused by chronic hypertension, which seriously affect people's life. The purpose of this study was to identify the potential biomarkers of HTN and understand its possible mechanisms. METHODS:The dataset numbered GSE28260 related to hypertensive and n...

journal_title：BMC nephrology

authors： Wang Z,Liu Z,Yang Y,Kang L

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...

journal_title：BMC nephrology

authors： Han M,Li Y,Liu M,Li Y,Cong B

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...

journal_title：BMC nephrology

authors： Kanda E,Ai M,Yoshida M,Kuriyama R,Shiigai T

更新日期：2013-01-09 00:00:00

abstract：BACKGROUND:Age and number of recipients in need of kidney re-transplantation are increasing. Re-transplantation practices and outcomes in elderly recipients are not previously explored. We aimed to retrospectively evaluate the outcomes of recipients 65 years and older receiving their second deceased donor allograft. M...

journal_title：BMC nephrology

authors： Heldal K,Hartmann A,Lønning K,Leivestad T,Reisæter AV,Line PD,Holdaas H,Midtvedt K

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:The predictive value of acute kidney injury (AKI) urinary biomarkers may depend on the time interval following tubular injury, thereby explaining in part the heterogeneous performance of these markers that has been reported in the literature. We studied the influence of timing on the predictive values of tub...

journal_title：BMC nephrology

authors： de Geus HR,Fortrie G,Betjes MG,van Schaik RH,Groeneveld AB

更新日期：2013-12-09 00:00:00

abstract：BACKGROUND:The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to ameliorate left ventricular hypertrophy in dialysis populations has become a research priority. Reduc...

journal_title：BMC nephrology

authors： Dunlop JL,Vandal AC,de Zoysa JR,Gabriel RS,Haloob IA,Hood CJ,Matheson PJ,McGregor DO,Rabindranath KS,Semple DJ,Marshall MR

更新日期：2013-07-15 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Efficient and safe delivery of care to dialysis patients is essential. Concerns have been raised regarding the ability of accountable care organizations to adequately serve this high-risk population. Little is known about primary care involvement in the care of dialysis patients. This study sought to describ...

journal_title：BMC nephrology

authors： Thorsteinsdottir B,Ramar P,Hickson LJ,Reinalda MS,Albright RC,Tilburt JC,Williams AW,Takahashi PY,Jeffery MM,Shah ND

更新日期：2017-10-25 00:00:00