Unexpected recovery from longterm renal failure in severe diffuse proliferative lupus nephritis.

abstract：BACKGROUND:The presence of glutathione transferase (GST) M1 null genotype (GSTM1-null) in end-stage renal disease (ESRD) patients is associated with lower overall survival rate in comparison to those with GSTM1-active variants. We examined association between GSTM1 and GSTT1 deletion polymorphisms as well as SNPs in GS...

journal_title：BMC nephrology

authors： Suvakov S,Damjanovic T,Pekmezovic T,Jakovljevic J,Savic-Radojevic A,Pljesa-Ercegovac M,Radovanovic S,Simic DV,Pljesa S,Zarkovic M,Mimic-Oka J,Dimkovic N,Simic T

更新日期：2014-01-14 00:00:00

abstract：BACKGROUND:The pathogenesis of falling is complex, and identification of risk factors may be essential for prevention. The relationship between renal disease and falls is unclear, and the goal of this study was to collect the available evidence and investigate the relationship between accidental falls and renal dysfunc...

journal_title：BMC nephrology

authors： López-Soto PJ,De Giorgi A,Senno E,Tiseo R,Ferraresi A,Canella C,Rodríguez-Borrego MA,Manfredini R,Fabbian F

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community-wide CKD management system has led to a decline in the incident rate of RRT and the lowest percenta...

journal_title：BMC nephrology

authors： Gallagher H,Methven S,Casula A,Thomas N,Tomson CR,Caskey FJ,Rose T,Walters SJ,Kennedy D,Dawnay A,Cassidy M,Fluck R,Rayner HC,Nation M

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of renal and cardiovascular (CV) disease progression in patients with chronic kidney disease (CKD). The...

journal_title：BMC nephrology

authors： Levin A,Rigatto C,Brendan B,Madore F,Muirhead N,Holmes D,Clase CM,Tang M,Djurdjev O,CanPREDDICT investigators.

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

journal_title：BMC nephrology

authors： Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chronic CsA-induced renal interstitial volume increase, tubule loss, and functional impairment in a rat mo...

journal_title：BMC nephrology

authors： Nielsen FT,Jensen BL,Hansen PB,Marcussen N,Bie P

更新日期：2013-02-20 00:00:00

abstract：BACKGROUND:Hypertensive nephropathy (HTN) is a kind of renal injury caused by chronic hypertension, which seriously affect people's life. The purpose of this study was to identify the potential biomarkers of HTN and understand its possible mechanisms. METHODS:The dataset numbered GSE28260 related to hypertensive and n...

journal_title：BMC nephrology

authors： Wang Z,Liu Z,Yang Y,Kang L

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Tissue derived biomarkers may offer utility as indicators of accumulated damage. Reduced thickness of retinal neuronal tissue and the vascular choroid have previously been associated with vascular damage and diabetes. We evaluated associations between retinal thickness, retinal microvascular and choroidal me...

journal_title：BMC nephrology

authors： Paterson EN,Ravindran ML,Griffiths K,Le Velly CA,Cardwell CC,McCarter RV,Nicol P,Chhablani JK,Rasheed MA,Vupparaboina KK,MacGillivray TJ,Harbinson M,Maxwell AP,Hogg RE,McKay GJ

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:FGF23 controls serum l,25(OH)2D3 levels and phosphate homeostasis. This study evaluates the effects of ferritin on intact PTH, FGF23, and l,25(OH)2D3 in patients with major thalassemia. It also evaluates FGF23 changes in patients with hypoparathyroidism to clarify the interaction between FGF23 and PTH in the...

journal_title：BMC nephrology

authors： Saki F,Salehifar A,Kassaee SR,Omrani GR

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Concentration of the urine is primarily regulated via vasopressin dependent aquaporin-2 water channels in the apical membrane of kidney principal cells. It is unclear whether urine concentration ability in ADPKD differs from other patients with similar degree of impaired renal function (non-ADPKD patients). ...

journal_title：BMC nephrology

authors： Malmberg MH,Mose FH,Pedersen EB,Bech JN

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (...

journal_title：BMC nephrology

authors： Bernardo AP,Oliveira JC,Santos O,Carvalho MJ,Cabrita A,Rodrigues A

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:This study describes chronic kidney disease of uncertain aetiology (CKDu), which cannot be attributed to diabetes, hypertension or other known aetiologies, that has emerged in the North Central region of Sri Lanka. METHODS:A cross-sectional study was conducted, to determine the prevalence of and risk factor...

journal_title：BMC nephrology

authors： Jayatilake N,Mendis S,Maheepala P,Mehta FR,CKDu National Research Project Team.

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...

journal_title：BMC nephrology

authors： Pellegrino AM,Annicchiarico Petruzzelli L,Riccio E,Pisani A

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to ameliorate left ventricular hypertrophy in dialysis populations has become a research priority. Reduc...

journal_title：BMC nephrology

authors： Dunlop JL,Vandal AC,de Zoysa JR,Gabriel RS,Haloob IA,Hood CJ,Matheson PJ,McGregor DO,Rabindranath KS,Semple DJ,Marshall MR

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality of hospitalized HIV-infected patients. METHODS:Retrospective analysis of a cohort of 433 hospitali...

journal_title：BMC nephrology

authors： Lopes JA,Melo MJ,Raimundo M,Fragoso A,Antunes F

更新日期：2013-02-11 00:00:00

abstract：BACKGROUND:The Reducing Disparities in Access to kidNey Transplantation Community Study (RaDIANT) was an End-Stage Renal Disease (ESRD) Network 6-developed, dialysis facility-level randomized trial testing the effectiveness of a 1-year multicomponent education and quality improvement intervention in increasing referral...

journal_title：BMC nephrology

authors： Hamoda RE,Gander JC,McPherson LJ,Arriola KJ,Cobb L,Pastan SO,Plantinga L,Browne T,Hartmann E,Mulloy L,Zayas C,Krisher J,Patzer RE

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in people living with CKD. This study's aim was to evaluate the relationship between frailty and sympto...

journal_title：BMC nephrology

authors： Nixon AC,Wilkinson TJ,Young HML,Taal MW,Pendleton N,Mitra S,Brady ME,Dhaygude AP,Smith AC

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:Patients undergoing haemodialysis (HD) are at higher risk of developing worse outcomes if they contract COVID-19. In our renal service we reduced HD frequency from thrice to twice-weekly in selected patients with the primary aim of reducing COVID 19 exposure and transmission between HD patients. METHODS:Dia...

journal_title：BMC nephrology

authors： Lodge MDS,Abeygunaratne T,Alderson H,Ali I,Brown N,Chrysochou C,Donne R,Erekosima I,Evans P,Flanagan E,Gray S,Green D,Hegarty J,Hyde A,Kalra PA,Lamerton E,Lewis D,Middleton R,New D,Nipah R,O'Donoghue D,O'Riordan

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:Current guidelines regarding plasma-sampling techniques for glomerular filtration rate (GFR) determination are inconsistent. Single-sample methods are commonly believed not to be precise enough to meet clinical demands. The present study compared the agreement between single- and dual- plasma sampling method...

journal_title：BMC nephrology

authors： Zhang Y,Sui Z,Yu Z,Li TF,Feng WY,Zuo L

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Approximately 4-6% of incident end stage renal disease (ESRD) patients in the U.S. recover enough kidney function to discontinue dialysis but there is considerable geographic variation. We undertook this study to investigate whether state-level variations in renal recovery among incident ESRD patients correl...

journal_title：BMC nephrology

authors： Chen Z,Lee BJ,McCulloch CE,Burrows NR,Heung M,Hsu RK,Pavkov ME,Powe NR,Saran R,Shahinian V,Hsu CY,Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. METHODS:Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. Serum OPG and fetuin-A levels...

journal_title：BMC nephrology

authors： Collado S,Coll E,Nicolau C,Azqueta M,Pons M,Cruzado JM,de la Torre B,Deulofeu R,Mojal S,Pascual J,Cases A

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:Bioimpedance analysis (BIA) has been reported as helpful in identifying hypervolemia. Observation data showed that hypervolemic maintenance hemodialysis (MHD) patients identified using BIA methods have higher mortality risk. However, it is not known if BIA-guided fluid management can improve MHD patients' su...

journal_title：BMC nephrology

authors： Liu L,Long G,Ren J,Li J,Xu J,Lei J,Li M,Qiu M,Yuan P,Sun W,Lin S,Liu W,Sun Y,Ma Y,Mao Y,Shen Y,Zuo L

更新日期：2012-09-25 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exer...

journal_title：BMC nephrology

authors： Kontos P,Alibhai SM,Miller KL,Brooks D,Colobong R,Parsons T,Jassal SV,Thomas A,Binns M,Naglie G

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Patients undergoing liver transplantation with preexisting renal dysfunction are prone to further renal impairment with the early postoperative use of Calcineurin-inhibitors. However, there is only little scientific evidence for the safety and efficacy of de novo CNI free "bottom-up" regimens in patients wit...

journal_title：BMC nephrology

authors： Schnitzbauer AA,Scherer MN,Rochon J,Sothmann J,Farkas SA,Loss M,Geissler EK,Obed A,Schlitt HJ

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:Post transplantation diabetes mellitus (PTDM) is a common and serious complication after renal transplantation with significant morbidity and mortality. Metformin has proven benefits in the general population and might be advantageous in the prevention and management of PTDM. METHODS:Transplantation and Dia...

journal_title：BMC nephrology

authors： Alnasrallah B,Goh TL,Chan LW,Manley P,Pilmore H

更新日期：2019-04-29 00:00:00

abstract：BACKGROUND:The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serology status and incident CKD in a large cohort of men and women. METHODS:Cohort study of 299,913 adult...

journal_title：BMC nephrology

authors： Hong YS,Ryu S,Chang Y,Caínzos-Achirica M,Kwon MJ,Zhao D,Shafi T,Lazo M,Pastor-Barriuso R,Shin H,Cho J,Guallar E

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables (blood flow rate, dialysate flow rate, and type of filter) in the hemodialysis procedure on the c...

journal_title：BMC nephrology

authors： Jang SM,Cardone KE,Nolin TD,Mason DL,Grabe DW

更新日期：2014-12-20 00:00:00