Determination of vancomycin and gentamicin clearance in an in vitro, closed loop dialysis system.

abstract：BACKGROUND:Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment decisions has not been evaluated. We sought to define the variability of these measurements and to d...

journal_title：BMC nephrology

authors： Patel R,Paredes W,Hall CB,Nader MA,Sapkota D,Folkert VW,Abramowitz MK

更新日期：2015-12-21 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage caused by its filtration. The existence of the so-called High Cut-Off (HCO) filters, possessing pores...

journal_title：BMC nephrology

authors： Cucchiari D,Reverter E,Blasco M,Molina-Andujar A,Carpio A,Sanz M,Escorsell A,Fernández J,Poch E

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of renal and cardiovascular (CV) disease progression in patients with chronic kidney disease (CKD). The...

journal_title：BMC nephrology

authors： Levin A,Rigatto C,Brendan B,Madore F,Muirhead N,Holmes D,Clase CM,Tang M,Djurdjev O,CanPREDDICT investigators.

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medica...

journal_title：BMC nephrology

authors： Scheel J,Reber S,Stoessel L,Waldmann E,Jank S,Eckardt KU,Grundmann F,Vitinius F,de Zwaan M,Bertram A,Erim Y

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and is an important cause of end-stage renal disease (ESRD). Exploring novel biomarkers is necessary for predicting the disease activity and progression of IgAN patients. The present study sought to investigate the value of serum C4 for p...

journal_title：BMC nephrology

authors： Bi TD,Zheng JN,Zhang JX,Yang LS,Liu N,Yao L,Liu LL

更新日期：2019-07-04 00:00:00

abstract：BACKGROUND:Depression and frailty contribute to the adverse clinical outcome of peritoneal dialysis (PD) patients. However, the interaction between depression and frailty in PD patients remains uncertain. We determined the prevalence of depression and frailty in prevalent Chinese PD patients, dissected the internal rel...

journal_title：BMC nephrology

authors： Chan GC,Ng JK,Chow KM,Kwan BC,Kwong VW,Pang WF,Cheng PM,Law MC,Leung CB,Li PK,Szeto CC

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND:A classification tree model (CT-PIRP) was developed in 2013 to predict the annual renal function decline of patients with chronic kidney disease (CKD) participating in the PIRP (Progetto Insufficienza Renale Progressiva) project, which involves thirteen Nephrology Hospital Units in Emilia-Romagna (Italy). Th...

journal_title：BMC nephrology

authors： Gibertoni D,Rucci P,Mandreoli M,Corradini M,Martelli D,Russo G,Mancini E,Santoro A

更新日期：2019-05-17 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:The Reducing Disparities in Access to kidNey Transplantation Community Study (RaDIANT) was an End-Stage Renal Disease (ESRD) Network 6-developed, dialysis facility-level randomized trial testing the effectiveness of a 1-year multicomponent education and quality improvement intervention in increasing referral...

journal_title：BMC nephrology

authors： Hamoda RE,Gander JC,McPherson LJ,Arriola KJ,Cobb L,Pastan SO,Plantinga L,Browne T,Hartmann E,Mulloy L,Zayas C,Krisher J,Patzer RE

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete remission rates in LN ...

journal_title：BMC nephrology

authors： Wright RD,Bannerman F,Beresford MW,Oni L

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:To identify patient and health system characteristics associated with late referral of patients with chronic kidney disease to nephrologists. METHODS:MEDLINE, CENTRAL, and CINAHL were searched using the appropriate MESH terms in March 2007. Two reviewers individually and in duplicate reviewed the abstracts ...

journal_title：BMC nephrology

authors： Navaneethan SD,Aloudat S,Singh S

更新日期：2008-02-25 00:00:00

abstract：BACKGROUND:High water hardness associated with high water fluoride and the geographical distribution of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka are well correlated. We undertook this study to observe the effects of high water hardness with high fluoride on kidney and liver in rats and efficacy of...

journal_title：BMC nephrology

authors： Perera T,Ranasinghe S,Alles N,Waduge R

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) has been established as a risk for cardiovascular diseases and mortality in hemodialysis patients. Energy intake (EI) is an important nutritional therapy for preventing MetS. We examined the association of self-reported dietary EI with metabolic abnormalities and MetS among hemodial...

journal_title：BMC nephrology

authors： Duong TV,Wong TC,Chen HH,Chen TW,Chen TH,Hsu YH,Peng SJ,Kuo KL,Liu HC,Lin ET,Wang CS,Tseng IH,Feng YW,Chang TY,Su CT,Yang SH

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:Concentration of the urine is primarily regulated via vasopressin dependent aquaporin-2 water channels in the apical membrane of kidney principal cells. It is unclear whether urine concentration ability in ADPKD differs from other patients with similar degree of impaired renal function (non-ADPKD patients). ...

journal_title：BMC nephrology

authors： Malmberg MH,Mose FH,Pedersen EB,Bech JN

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one's residence to dialysis centre at time of dialysis initiation, and whether region or duration of pre-dialysis care are important eff...

journal_title：BMC nephrology

authors： Miller LM,Vercaigne LM,Moist L,Lok CE,Tangri N,Komenda P,Rigatto C,Mojica J,Sood MM

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Peripheral arterial disease (PAD) is common in patients with end-stage renal disease on hemodialysis, but is frequently underdiagnosed. The risk factors for PAD are well known within the general population, but they differ somewhat in hemodialysis patients. This study aimed to determine the prevalence of PAD...

journal_title：BMC nephrology

authors： Ašćerić RR,Dimković NB,Trajković GŽ,Ristić BS,Janković AN,Durić PS,Ilijevski NS

更新日期：2019-07-26 00:00:00

abstract：BACKGROUND:Anaemia is a known risk factor for cardiovascular disease and treating anaemia in chronic kidney disease (CKD) may improve outcomes. However, little is known about the scope to improve primary care management of anaemia in CKD. METHODS:An observational study (N = 1,099,292) with a nationally representative ...

journal_title：BMC nephrology

authors： Dmitrieva O,de Lusignan S,Macdougall IC,Gallagher H,Tomson C,Harris K,Desombre T,Goldsmith D

更新日期：2013-01-25 00:00:00

abstract：BACKGROUND:Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in people living with CKD. This study's aim was to evaluate the relationship between frailty and sympto...

journal_title：BMC nephrology

authors： Nixon AC,Wilkinson TJ,Young HML,Taal MW,Pendleton N,Mitra S,Brady ME,Dhaygude AP,Smith AC

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:Primary nephrotic syndrome (PNS) is a common glomerular disease in children. T cell dysfunction plays a crucial role in the pathogenesis of PNS. Moreover, dysbiosis of gut microbiota contributes to immunological disorders. Whether the initial therapy of PNS affects gut microbiota remains an important questio...

journal_title：BMC nephrology

authors： Kang Y,Feng D,Law HK,Qu W,Wu Y,Zhu GH,Huang WY

更新日期：2019-11-26 00:00:00

abstract：BACKGROUND:HS219 (40 mg chitosan-loaded chewing gum) is designed to bind salivary phosphorus as an add-on to available phosphorus binders. We performed a randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of HS219 in hemodialysis (HD) patients with hyperphosphatemia as an add-on to p...

journal_title：BMC nephrology

authors： Akizawa T,Tsuruta Y,Okada Y,Miyauchi Y,Suda A,Kasahara H,Sasaki N,Maeda Y,Suzuki T,Matsui N,Niwayama J,Suzuki T,Hara H,Asano Y,Komemushi S,Fukagawa M

更新日期：2014-06-25 00:00:00

abstract：BACKGROUND:TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organomegaly. TAFRO syndrome has only recently been described, and many clinicians are unaware of this disea...

journal_title：BMC nephrology

authors： Zhou Q,Zhang Y,Zhou G,Zhu J

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:In a previous study we showed that troponin I (TnI) > 0.42 ng/mL predicted the need of dialysis in a group of 29 septic patients admitted to the intensive care unit (ICU). We aimed to confirm such finding in a larger independent sample. METHODS:All septic patients admitted to an ICU from March 2016 to Febru...

journal_title：BMC nephrology

authors： de Almeida Thiengo D,Strogoff-de-Matos JP,Lugon JR,Graciano ML

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to ameliorate left ventricular hypertrophy in dialysis populations has become a research priority. Reduc...

journal_title：BMC nephrology

authors： Dunlop JL,Vandal AC,de Zoysa JR,Gabriel RS,Haloob IA,Hood CJ,Matheson PJ,McGregor DO,Rabindranath KS,Semple DJ,Marshall MR

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study was conducted to evaluate the relationship between central arterial stiffness and serum OPG levels ...

journal_title：BMC nephrology

authors： Hou JS,Lin YL,Wang CH,Lai YH,Kuo CH,Subeq YM,Hsu BG

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND:Sustained low efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. SLED may reduce the hemodynamic perturbations of intermittent hemodialysis, while obviating the resource demands of CRRT. Althou...

journal_title：BMC nephrology

authors： Kitchlu A,Adhikari N,Burns KE,Friedrich JO,Garg AX,Klein D,Richardson RM,Wald R

更新日期：2015-08-04 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00