Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation.

abstract：BACKGROUND:Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one's residence to dialysis centre at time of dialysis initiation, and whether region or duration of pre-dialysis care are important eff...

journal_title：BMC nephrology

authors： Miller LM,Vercaigne LM,Moist L,Lok CE,Tangri N,Komenda P,Rigatto C,Mojica J,Sood MM

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a common comorbid condition in coronary heart disease (CHD). CKD predisposes the patient to acute kidney injury (AKI) during hospitalization. Data on awareness of kidney dysfunction among CHD patients and their treating physicians are lacking. In the current cross-sectional an...

journal_title：BMC nephrology

authors： Wagner M,Wanner C,Schich M,Kotseva K,Wood D,Hartmann K,Fette G,Rücker V,Oezkur M,Störk S,Heuschmann PU

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been proposed recently and adding laser microdissection followed by mass spectrometry (LMD/MS) to conventiona...

journal_title：BMC nephrology

authors： Adachi M,Kitamura M,Muta K,Maekawa A,Uramatsu T,Tadokoro M,Funakoshi S,Hisano S,Kuwahara N,Shimizu A,Mukae H,Nishino T

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Little is known about the changes in disease makers and risk factors in patients with chronic kidney disease (CKD) under nephrological care in Africa. This study aimed to evaluate the baseline level of markers of CKD and their 12-month time-trend in newly referred patients in a tertiary hospital in Cameroon....

journal_title：BMC nephrology

authors： Patrice HM,Pascal KA,François KF,Hilaire D,Solange DM,Gloria AE,Pierre CS

更新日期：2020-03-18 00:00:00

abstract：BACKGROUND:Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that measures core body temperature, current practice is to use peripheral thermometers. A better understandi...

journal_title：BMC nephrology

authors： Lunney M,Tonelli B,Lewis R,Wiebe N,Thomas C,MacRae J,Tonelli M

更新日期：2018-06-14 00:00:00

abstract：BACKGROUND:Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a "cruel alliance", with CVD responsible for about half of all deaths among CKD patients. Chronic kidney disease patients are more likely to die from CVD than progress to end stage kidney disease (ES...

journal_title：BMC nephrology

authors： Oguntola SO,Hassan MO,Duarte R,Vachiat A,Manga P,Naicker S

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regulating cytoskeletal arc...

journal_title：BMC nephrology

authors： Huang Z,Zhang L,Chen Y,Zhang H,Yu C,Zhou F,Zhang Z,Jiang L,Li R,Ma J,Li Z,Lai Y,Lin T,Zhao X,Zhang Q,Zhang B,Ye Z,Liu S,Wang W,Liang X,Liao R,Shi W

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:A positive pregnancy test in acute or chronically ill patients has implications for the use of potentially mutagenic or teratogenic products in urgent medical therapies such as the use of chemotherapies or therapies with immunosuppressants, for anesthesia, and for time-sensitive indications like urgent surge...

journal_title：BMC nephrology

authors： Haninger-Vacariu N,Herkner H,Lorenz M,Säemann M,Vychytil A,Jansen M,Marculescu R,Kramar R,Sunder-Plassmann G,Schmidt A

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients. We examined which definition of body weight is most effective in establishing a urinary diagnosis of AKI in septic...

journal_title：BMC nephrology

authors： Katayama S,Koyama K,Goto Y,Koinuma T,Tonai K,Shima J,Wada M,Nunomiya S

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS:We examined the role of type I collagen (collagen I) and membrane...

journal_title：BMC nephrology

authors： Liu B,Li C,Liu Z,Dai Z,Tao Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...

journal_title：BMC nephrology

authors： Pellegrino AM,Annicchiarico Petruzzelli L,Riccio E,Pisani A

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables (blood flow rate, dialysate flow rate, and type of filter) in the hemodialysis procedure on the c...

journal_title：BMC nephrology

authors： Jang SM,Cardone KE,Nolin TD,Mason DL,Grabe DW

更新日期：2014-12-20 00:00:00

abstract：BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...

journal_title：BMC nephrology

authors： Shiotsu Y,Mori Y,Nishimura M,Hatta T,Imada N,Maki N,Iida K,Iwamoto N,Matsuoka E,Tamagaki K,Kosaki A

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and have been linked to acute kidney injury (AKI), chronic kidney disease (CKD) and cardiovascular disease (CVD). Patients who survive an AKI episode are at risk for future adverse kidney and cardiovascular outcomes. The objective of our study wa...

journal_title：BMC nephrology

authors： Lipworth L,Abdel-Kader K,Morse J,Stewart TG,Kabagambe EK,Parr SK,Birdwell KA,Matheny ME,Hung AM,Blot WJ,Ikizler TA,Siew ED

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatemia and renal outcome in non-CKD patients has not been studied. Furthermore, the clinical implication...

journal_title：BMC nephrology

authors： Moon H,Chin HJ,Na KY,Joo KW,Kim YS,Kim S,Han SS

更新日期：2019-09-18 00:00:00

abstract：BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

journal_title：BMC nephrology

authors： Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...

journal_title：BMC nephrology

authors： Gillion V,Jadoul M,Aydin S,Godefroid N

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:The diagnosis of myeloma, a plasma dyscrasia, often results from the workup of unexplained renal disease. Persistent renal failure in myeloma is commonly caused by tubular nephropathy due to circulating immunoglobulins and free light chains. Myeloma cast nephropathy is characterized by crystalline precipitat...

journal_title：BMC nephrology

authors： Wu CK,Yang AH,Lai HC,Lin BS

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...

journal_title：BMC nephrology

authors： Yatabe MS,Yatabe J,Takano K,Murakami Y,Sakuta R,Abe S,Sanada H,Kimura J,Watanabe T

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate immunity, an excessive formation of NETs has adverse effects, e.g., induction of anti-neutrophil cy...

journal_title：BMC nephrology

authors： Shida H,Hashimoto N,Kusunoki Y,Hattanda F,Ogawa Y,Hayashi T,Nakazawa D,Masuda S,Tomaru U,Ishizu A

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Concentration of the urine is primarily regulated via vasopressin dependent aquaporin-2 water channels in the apical membrane of kidney principal cells. It is unclear whether urine concentration ability in ADPKD differs from other patients with similar degree of impaired renal function (non-ADPKD patients). ...

journal_title：BMC nephrology

authors： Malmberg MH,Mose FH,Pedersen EB,Bech JN

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:To identify patient and health system characteristics associated with late referral of patients with chronic kidney disease to nephrologists. METHODS:MEDLINE, CENTRAL, and CINAHL were searched using the appropriate MESH terms in March 2007. Two reviewers individually and in duplicate reviewed the abstracts ...

journal_title：BMC nephrology

authors： Navaneethan SD,Aloudat S,Singh S

更新日期：2008-02-25 00:00:00

abstract：BACKGROUND:The aim of the study was to assess the association between chronic kidney disease (CKD) and obesity in predicting CKD among Chinese adults, distinguishing between 5 different adiposity indices: visceral fat index (VFI), percentage body fat (PBF), body mass index (BMI), waist circumference (WC) and waist-to-h...

journal_title：BMC nephrology

authors： Dong Y,Wang Z,Chen Z,Wang X,Zhang L,Nie J,Zheng C,Wang J,Shao L,Tian Y,Gao R

更新日期：2018-02-17 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality of hospitalized HIV-infected patients. METHODS:Retrospective analysis of a cohort of 433 hospitali...

journal_title：BMC nephrology

authors： Lopes JA,Melo MJ,Raimundo M,Fragoso A,Antunes F

更新日期：2013-02-11 00:00:00

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Transplant tourism entails movement of recipient, donor or both to a transplant centre outside their country of residence. This has been reported in many countries; and has variously been associated with organ trade. The objective of this study is to determine the frequency and pattern of transplant tourism ...

journal_title：BMC nephrology

authors： Okafor UH

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:A marked reduction in serum levels of bioactive insulin-like growth factor-I (IGF-I) has been observed in fasting hemodialysis (HD) patients during a 4-h HD session. The aim of the present study was to investigate the beneficial effect of hyperinsulinemia during HD on bioactive IGF-I and inflammatory biomark...

journal_title：BMC nephrology

authors： Reinhard M,Frystyk J,Jespersen B,Bjerre M,Christiansen JS,Flyvbjerg A,Ivarsen P

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Sustained low efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. SLED may reduce the hemodynamic perturbations of intermittent hemodialysis, while obviating the resource demands of CRRT. Althou...

journal_title：BMC nephrology

authors： Kitchlu A,Adhikari N,Burns KE,Friedrich JO,Garg AX,Klein D,Richardson RM,Wald R

更新日期：2015-08-04 00:00:00