RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal.

abstract：BACKGROUND:Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal safety of anabolic-androgenic steroids and growth hormone (GH). METHODS:The search strategy was in ...

journal_title：BMC nephrology

authors： Davani-Davari D,Karimzadeh I,Khalili H

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:The clinical consequences of starting chronic peritoneal dialysis (PD) after emergent dialysis via a temporary hemodialysis (HD) catheter has rarely been evaluated within a full spectrum of treated end-stage renal disease (ESRD). We investigated the longer-term outcomes of patients undergoing emergent-start ...

journal_title：BMC nephrology

authors： Li WY,Wang YC,Hwang SJ,Lin SH,Wu KD,Chen YM

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion o...

journal_title：BMC nephrology

authors： Karmarkar MG,Hule GP,Hase NK,Mehta PR,Walter SR,Sriprakash KS

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) has been established as a risk for cardiovascular diseases and mortality in hemodialysis patients. Energy intake (EI) is an important nutritional therapy for preventing MetS. We examined the association of self-reported dietary EI with metabolic abnormalities and MetS among hemodial...

journal_title：BMC nephrology

authors： Duong TV,Wong TC,Chen HH,Chen TW,Chen TH,Hsu YH,Peng SJ,Kuo KL,Liu HC,Lin ET,Wang CS,Tseng IH,Feng YW,Chang TY,Su CT,Yang SH

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:Increased leucine-rich α2-glycoprotein-1 (LRG1) has been observed in various inflammatory and autoimmune diseases. We aimed to explore the expression and role of LRG1 in lupus nephritis (LN). METHODS:Plasma LRG1 (pLRG1) was measured by enzyme-linked immunosorbent assay in 101 patients with renal biopsy-prov...

journal_title：BMC nephrology

authors： Yang Y,Luo R,Cheng Y,Liu T,Dai W,Li Y,Ge S,Xu G

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:A previous cohort study indicated a significant association of lower baseline level of physical activity in hemodialysis patients with elevated risks of mortality. However, there have been no reports regarding the association between changes in physical activity over time and mortality in hemodialysis patien...

journal_title：BMC nephrology

authors： Shimoda T,Matsuzawa R,Yoneki K,Harada M,Watanabe T,Matsumoto M,Yoshida A,Takeuchi Y,Matsunaga A

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD) events, and a number of reports have shown a relationship between CKD and CVD in pre-dialysis or maintenance dialysis patients. However, few studies have reported serial observations during dialysis initiation and mai...

journal_title：BMC nephrology

authors： Inaguma D,Koide S,Takahashi K,Hayashi H,Hasegawa M,Yuzawa Y

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations ar...

journal_title：BMC nephrology

authors： Kumar V,Yadav AK,Yasuda Y,Horio M,Kumar V,Sahni N,Gupta KL,Matsuo S,Kohli HS,Jha V

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) is a well defined risk factor for subsequent bacteremia and death in various groups of patients, but its impact on outcome in patients receiving long-term hemodialysis (HD) is under debate. METHODS:This prospective interventional coh...

journal_title：BMC nephrology

authors： Schmid H,Romanos A,Schiffl H,Lederer SR

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:HS219 (40 mg chitosan-loaded chewing gum) is designed to bind salivary phosphorus as an add-on to available phosphorus binders. We performed a randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of HS219 in hemodialysis (HD) patients with hyperphosphatemia as an add-on to p...

journal_title：BMC nephrology

authors： Akizawa T,Tsuruta Y,Okada Y,Miyauchi Y,Suda A,Kasahara H,Sasaki N,Maeda Y,Suzuki T,Matsui N,Niwayama J,Suzuki T,Hara H,Asano Y,Komemushi S,Fukagawa M

更新日期：2014-06-25 00:00:00

abstract：BACKGROUND:Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%. CASE PRESENTATION:A 35-year-old non-smoking African man experienced a 2-week history of painless, profuse and persisten...

journal_title：BMC nephrology

authors： Le Joncour A,Mesnard L,Hertig A,Robert T

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:Although hemodialysis (HD) adequacy, single-pool Kt/Vurea (spKt/V), is inversely correlated with body size, each is known to affect patient survival in the same direction. Therefore, we sought to examine the relationship between HD adequacy and mortality according to body mass index (BMI) in HD patients and ...

journal_title：BMC nephrology

authors： Hong WP,Lee YJ

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chronic lesions are absent and adequate anti-inflammatory therapy is immediately initiated. CASE PRESENT...

journal_title：BMC nephrology

authors： Ross S,Benz K,Sauerstein K,Amann K,Dötsch J,Dittrich K

更新日期：2012-08-06 00:00:00

abstract：BACKGROUND:Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment decisions has not been evaluated. We sought to define the variability of these measurements and to d...

journal_title：BMC nephrology

authors： Patel R,Paredes W,Hall CB,Nader MA,Sapkota D,Folkert VW,Abramowitz MK

更新日期：2015-12-21 00:00:00

abstract：BACKGROUND:Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exer...

journal_title：BMC nephrology

authors： Kontos P,Alibhai SM,Miller KL,Brooks D,Colobong R,Parsons T,Jassal SV,Thomas A,Binns M,Naglie G

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent worldwide health problems with an epidemic extent. Therefore, attention must be given to the optimisation of patient care, as gaps in the care of CKD and ESRD patients are well documented. As part of a multidisciplinary patient care st...

journal_title：BMC nephrology

authors： Stemer G,Lemmens-Gruber R

更新日期：2011-07-22 00:00:00

abstract：BACKGROUND:Poor physical performance and protein-energy wasting (PEW) are health issues of major concern in haemodialysis patients. The conventional haemodialysis (CHD) regime, three times per week 3-5 h, is subject of discussion because of high morbidity and mortality rates. When patients switch from CHD to longer dia...

journal_title：BMC nephrology

authors： Dam M,Neelemaat F,Struijk-Wielinga T,Weijs PJ,van Jaarsveld BC

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...

journal_title：BMC nephrology

authors： Diena D,Messina M,De Biase C,Fop F,Scardino E,Rossetti MM,Barreca A,Verri A,Biancone L

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:The poorly differentiated renal cell carcinoma (RCC) with rhabdomyosarcomatous sarcomatoid differentiation shows a severely aggressive biological behavior characterized by rapid disease progression. Preoperative identification of the subtype with the prognostic factors and imaging features of sarcomatoid ren...

journal_title：BMC nephrology

authors： Liang X,Liu Y,Ran P,Tang M,Xu C,Zhu Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:As a result of difficulties related to their illness, diagnosis and treatment, patients with end-stage renal disease experience significant emotional and psychological problems, which untreated can have considerable negative impact on their health and wellbeing. Despite evidence that patients desire improved...

journal_title：BMC nephrology

authors： Taylor F,Taylor C,Baharani J,Nicholas J,Combes G

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Previous studies have not described the relationship between reducing radial artery diameter as well as increasing age and functional maturation of the radio-cephalic arteriovenous fistula (RCAVF) and no data identify these as linear relationship. The objective of this study was to perform trend analysis to ...

journal_title：BMC nephrology

authors： Wan ZM,Hu B,Lai QQ,Gao XJ,Tu B,Zhou Y,Zhao WB

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Parents' adaptation affects the health outcomes of children with chronic kidney diseases (CKD). Identifying factors that affect parents' adaptation is necessary to understand their adaptation status. This study aims to explore factors related to the adaptation of parents who have children with CKD. METHODS:...

journal_title：BMC nephrology

authors： Khorsandi F,Parizad N,Feizi A,Hemmati MaslakPak M

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

journal_title：BMC nephrology

authors： Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. METHODS:In a Taiwan nati...

journal_title：BMC nephrology

authors： Lin TH,Hsin HT,Wang CL,Lai WT,Li AH,Kuo CT,Hwang JJ,Chiang FT,Chang SC,Chang CJ,Taiwan ACS Full Spectrum Registry Investigators.

更新日期：2014-04-23 00:00:00

abstract：BACKGROUND:Patients with an impaired renal function show a high incidence of bone and mineral disturbances. These 'chronic kidney disease - mineral and bone disorders' (CKD-MBD) range from high turnover osteoporosis to adynamic bone disease. Currently, the histomorphometric analysis of a bone biopsy taken from the ilia...

journal_title：BMC nephrology

authors： Hiller RG,Patecki M,Neunaber C,Reifenrath J,Kielstein JT,Kielstein H

更新日期：2017-04-13 00:00:00

abstract：BACKGROUND:Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictive biomarker of acute kidney injury and may increase after cardiopulmonary bypass (C...

journal_title：BMC nephrology

authors： Friedrich MG,Bougioukas I,Kolle J,Bireta C,Jebran FA,Placzek M,Tirilomis T

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly related to cardiovascular diseases. We explored the potential association of ScysC with arterial stiffness...

journal_title：BMC nephrology

authors： Dinic M,Maillard N,Thibaudin D,Jannot M,Masson I,Alamartine E,Mariat C

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. METHODS:The ALIMAR-C2 study is a case-control study to assess the association between metformin and l...

journal_title：BMC nephrology

authors： Pedrós C,Ávila M,Gómez-Lumbreras A,Manríquez M,Morros R,ALIMAR-C2 Study Group.

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the GLA gene, followed by deficiency in α-galactosidase A (α-gal) activity. Nephrotic syndrome, as the renal phenotype of FD, is unusual. Here, we report the rare case of a patient with FD with nephrotic syndrome whose protei...

journal_title：BMC nephrology

authors： Fujisawa H,Nakayama Y,Nakao S,Yamamoto R,Kurokawa Y,Nakamura N,Nagata A,Tsukimura T,Togawa T,Sakuraba H,Fukami K

更新日期：2019-12-17 00:00:00